no_english_version
no_arabic_version
Mayo Clinic
  • Request an Appointment
  • Find a Doctor
  • Find a Job
  • Give Now
  • Log in to Patient Account
  • English
    • Español
    • العربية
    • 简体中文
  • Twitter
  • Facebook
  • Pinterest
  • YouTube
  • English
    • Español
    • العربية
    • 简体中文
mayo-mobile-logo-image
  • Menu
  • Search
All Mayo Clinic Topics
  • Care at Mayo Clinic
    • Overview
    • Appointments
    • Locations
    • Patient & Visitor Guide
    • International Services
    • Medical Departments & Centers
    • Doctors & Medical Staff
    • Patient Online Services
    • Billing & Insurance
    • Clinical Trials
    • International Business Collaborations
    • About Mayo Clinic
    • Contact Us
  • Health Information
    • Overview
    • Diseases & Conditions A-Z
    • Symptoms A-Z
    • Tests & Procedures A-Z
    • Drugs & Supplements A-Z
    • Health Books
    • Healthy Living Program
    • Mayo Clinic Health Letter
    • Mayo Clinic Voice Apps
    • Healthy Lifestyle

    Featured conditions

    Brain tumor, breast cancer, colon cancer, congenital heart disease, heart arrhythmia. See more conditions.
  • For Medical Professionals
    • Overview
    • Provider Relations
    • CareLink Online Referrals
    • Continuing Medical Education
    • Mayo Clinic Laboratories
    • AskMayoExpert
    • Video Center
    • Journals and Publications
  • Research
    • Overview
    • Research Faculty
    • Laboratories
    • Core Facilities
    • Centers & Programs
    • Departments & Divisions
    • Clinical Trials
    • Institutional Review Board
    • Postdoctoral Fellowships
    • Training Grant Programs
  • College of Medicine and Science
    • Overview
    • Mayo Clinic Graduate School of Biomedical Sciences
    • Mayo Clinic Alix School of Medicine
    • Mayo Clinic School of Continuous Professional Development
    • Mayo Clinic School of Graduate Medical Education
    • Mayo Clinic School of Health Sciences
  • Giving to Mayo Clinic
    • Overview
    • Give Now
    • Philanthropy in Action
    • Frequently Asked Questions
    • Contact Us to Give
Centers and Programs

Center for Biomedical Discovery

  • About
    • About
    • Overview
    • Leadership
    • Center Advisory Members
  • Research Platforms
    • Research Platforms
    • Cancer and Cell Aging
    • Immunity and Fibrosis
    • Metabolism and Molecular Nutrition
  • News and Events
    • News and Events
    • Past Events
  • Publications
  • Career Development
    • Career Development
    • Verline Justilien, Ph.D.
    • Ian R. Lanza, Ph.D.
    • Jian Yuan, Ph.D.
  • Connect
    • Connect
    • Collaborations
    • Contact
  • Metabolism and molecular nutrition platform

    The Metabolism and Diabetes biomedical research platform studies the processes of obesity, fat storage and utilization, cancer metabolism, insulin regulation, and related diseases.
    More

  • Metabolism and molecular nutrition platform

    The Metabolism and Diabetes biomedical research platform studies the processes of obesity, fat storage and utilization, cancer metabolism, insulin regulation, and related diseases.
    More

  • Metabolism and molecular nutrition platform

    The Metabolism and Diabetes biomedical research platform studies the processes of obesity, fat storage and utilization, cancer metabolism, insulin regulation, and related diseases.
    More

  • Metabolism and molecular nutrition platform

    The Metabolism and Diabetes biomedical research platform studies the processes of obesity, fat storage and utilization, cancer metabolism, insulin regulation, and related diseases.
    More

  • Metabolism and molecular nutrition platform

    The Metabolism and Diabetes biomedical research platform studies the processes of obesity, fat storage and utilization, cancer metabolism, insulin regulation, and related diseases.
    More

Diseases related to defects in metabolism cause significant health care burden and impact the quality of life of those affected. Many of these diseases — such as obesity, type 2 diabetes mellitus, cardiovascular disease, age-related diseases and some forms of cancer — are increasing in epidemic proportion.

The Center for Biomedical Discovery's metabolism and molecular nutrition biomedical research platform provides new mechanistic insights into metabolic-based diseases and how they might be treated by:

  • Improving understanding of the basic regulatory mechanisms underlying systems that supply energy to the cell, organs and whole body
  • Determining how these regulatory systems fail or produce detrimental side effects, leading to disease
  • Identifying therapies and treatments to prevent dysregulation of these systems and ameliorate the adverse effects of system failure

Most bodily processes and cells need energy, which is provided by complex, highly controlled systems that convert fuel (food) to various chemical forms of stored energy.

The liver, muscle and fat store most of the body's energy needs. These stored supplies in organs lie at the core of many metabolic-related diseases and conditions. On a cellular level, when these organs retain an overabundance of stored fat or starch — or are placed under additional conditions of stress or inflammation — they can become damaged or diseased. This is especially pronounced when fat in the abdominal cavity (omentum) becomes inflamed.

Grants

Team science grants foster new collaborations of scientists from diverse fields to drive innovative, cutting-edge research focused on understanding biological processes that contribute to human disease.

  • Active Grants — Metabolism and Molecular Nutrition Platform - GrantsActive Grants — Metabolism and Molecular Nutrition Platform
  • Grant Archives — Metabolism and Molecular Nutrition Platform - GrantsGrant Archives — Metabolism and Molecular Nutrition Platform

More About This Platform

  • News and articles - More About This PlatformNews and articles
  • View platform publications - More About This PlatformView platform publications

Contact

The platform director welcomes your input and feedback.

Contact us
.

Mayo Clinic Footer

  • Request Appointment
  • Give Now
  • Contact Us
  • About Mayo Clinic
  • Employees
  • Site Map
  • About This Site

Legal Conditions and Terms

Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below.

  • Terms and Conditions
  • Privacy Policy
  • Notice of Privacy Practices
  • Notice of Nondiscrimination
  • Manage Cookies

Advertising

Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. Mayo Clinic does not endorse any of the third party products and services advertised.

  • Advertising and sponsorship policy
  • Advertising and sponsorship opportunities

Reprint Permissions

A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

© 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved.