Biospecimens and Clinical Database Core
The Biospecimens and Clinical Database Core supports all four research projects in the Mayo Clinic Multiple Myeloma SPORE and is responsible for sample collection, processing, tracking and allocation.
The core also provides services that include integration of gene expression profiling (GEP), next-generation sequencing, fluorescence in situ hybridization (FISH) and flow cytometry, all of which further enrich the data associated with each patient.
The core coordinates data collection, database development and maintenance, and data quality control. It provides a mechanism of consistent and compatible data handling, facilitating management of collected data and integration with data from existing Mayo Clinic resources.
The core also generates and completes data-mining projects using existing clinical data, including exploration of flow cytometry, FISH and GEP. Amassing a large volume of clinical data in one system allows for the proliferation of ideas for data-mining projects.
The focus during the current five-year SPORE grant period includes exploring the roles of six-color peripheral blood flow cytometry and eight-color bone marrow flow cytometry in the biological and genomic characteristics of multiple myeloma.
Co-leaders of the Biospecimens and Clinical Database Core are: