Biospecimens and Clinical Database Core

To achieve the overall goal of the Mayo Clinic Multiple Myeloma SPORE of advancing the understanding of the mechanisms of myeloma pathogenesis, risk factors and therapy outcomes, we have developed a highly functioning, state-of-the-art Biospecimens and Clinical Database Core to support the SPORE investigative team.

The core provides a coordinated, centralized and dedicated mechanism for the procurement, processing and annotation of biospecimens from patients with plasma cell disorders, including multiple myeloma, smoldering multiple myeloma, monoclonal gammopathy of undetermined significance, immunoglobulin light chain amyloidosis and Waldenstrom macroglobulinemia.

The core's goal is to procure, process and accurately classify a variety of biological specimens on all patients involved in SPORE protocols and all patients with plasma cell disorders seen at Mayo Clinic in Arizona, Florida and Minnesota.

Core leaders

Co-directors of the Biospecimens and Clinical Database Core are:

• Angela Dispenzieri, M.D.
• Rafael Fonseca, M.D.
• Dragan Jevremovic, M.D., Ph.D.
• Aneel Paulus, M.D., M.S.