Participating labs

Mayo Clinic researchers and laboratories participating in the Celebration of Research:

Researcher name Lab name/focus area Description
Peter Amadio, M.D. Motion capture/friction
Tendon and Soft Tissue Biology Lab
Researches injuries to tendons and soft tissues by studying orthopedics, biomechanics, biochemistry, dynamic ultrasound, and molecular and cell biology.
Daniel D. Billadeau, Ph.D. Confocal imaging Researchers use wet lab technology to stain and visualize intracellular proteins and organelles using organelle-specific fluorescent proteins and fluorescent antibodies.
Eduardo N. Chini, M.D., Ph.D. Anesthesia
Anesthesiology and Perioperative Medicine Research
Researchers are studying anesthetic effects on subcellular function to reduce the need for perioperative transfusions, improve chronic pain management and the use of gene therapy to treat cardiovascular disease in the perioperative period.
Doo-Sup Choi, Ph.D. PCR/ Western Blot / microscope observation
Neurobiology of Alcoholism and Drug Addiction Lab
Investigates, identifies and validates the roles of genetic components in alcoholism and drug addiction.
Peter J. Dyck, M.D. Neurology – peripheral nerve fibers Researchers are studying methodologies to discover the neuropathological basis of the various neuropathies, such as diabetic polyneuropathy, amyloid polyneuropathy, hereditary sensorimotor polyneuropathy and uremic neuropathies.
Martin E. Fernandez-Zapico, M.D. Cancer cell cultures and epigenetic assays
Cell Biology Program
Defines the molecular and cellular basis of neoplastic transformation, growth and metastasis, and provides insights into normal and aberrant functions of genetic lesions.
Michael P. Fautsch, Ph.D. Ophthalmology
Ophthalmology Research
Researchers seek to understand the physiology of intraocular pressure regulation related to the development of glaucoma to prevent and treat the disease by regulating pressure and preserving the function of the optic nerve.
Martin E. Fernandez-Zapico Oncology
Gastrointestinal Cancer Program
Focuses on the cellular and molecular characterization of epigenetic pathways regulating pancreatic carcinogenesis, studying the modulation of chromatin and nuclear dynamics by oncogenic cascades and its impact in gene expression regulation, a critical step during pancreatic neoplastic transformation.
Evanthia Galanis, M.D. Molecular Medicine
Molecular Medicine
Researchers are developing and optimizing novel virotherapy approaches with special emphasis on paramyxoviruses ─ testing a number of different strategies, including use of therapeutic transgenes; trackable markers; combinations with small molecules, cytotoxic agents and radiation therapy; re-targeting of viral strains against tumor-specific antigens; development of novel viral delivery approaches; and exploration of immunomodulatory methods to modify humoral and innate immunity as a means of optimizing virotherapy efficacy.
James F. Greenleaf, Ph.D. Ultrasound plexiglass
Ultrasound Imaging Lab
Advanced ultrasound and acoustic sciences with a primary focus on developing new applications in medical and biological areas.
Susan Hallbeck, Ph.D.
Renaldo C. Blocker, Ph.D.
Melissa (Missy) Morrow, Ph.D.
Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery
Human Factors Engineering
In human factors engineering and systems integration, scientists use ergonomics and organization science to identify and correct incompatibilities among people, technology and work environments. Research focuses on improving technologies and systems to be as effective as possible within the physical and psychological limitations of humans.
Timothy Hewett, Ph.D. Orthopedic Biomechanics Team scientists focus on the development and application of techniques to prevent and treat sports-related injuries by working to make scientific, data-supported advancements that lead to efficacious changes in practice relative to joint injury risk screening, injury risk prevention and post-injury rehabilitation.
David R. Holmes, III, Ph.D. Biomedical Imaging
Physiology and Biomedical Engineering
Scientists, engineers and physicians work together to translate basic discoveries in medicine and engineering into enhanced patient care by studying how the body works normally, investigating processes that contribute to a variety of diseases and conditions, and developing approaches to cure them.
Michael J. Joyner, M.D. Metabolic exercise testing
Human and Integrative Physiology and Clinical Pharmacology Lab
Studies how the peripheral circulation and autonomic reflexes adapt to physical stresses, and how gender and age influence these factors.
Jeong-Heon Lee, Ph.D. Epigenetic methodologies
Epigenomics Development Laboratory in the Center for Individualized Medicine
Researchers are deciphering epigenetic mechanisms in the etiology and progression of human diseases using next-generation sequencing (NGS)-based epigenetic technologies to identify disease-specific epigenetic features for early detection, prognosis and treatment stratification.
Lilach O. Lerman, M.D., Ph.D. 2D and 3D visualizations and renderings of kidneys
Renovascular Disease Lab
Studies renal and cardiovascular physiology and pathophysiology to develop novel diagnostic and therapeutic techniques.
Hongfang Liu, Ph.D. Medical Informatics, natural language processing
Medical Informatics
Health Sciences Research
The team collects, organizes and provides access to clinical information, using that information to develop and test hypotheses, validating those hypotheses against real-world health problems, and incorporating the outcomes of those tests back into the knowledge base.
Louis (Jim) J. Maher III, Ph.D. Polymer chemistry/DNA structure
Nucleic Acid Structure and Recognition Lab
Develops new approaches to study DNA flexibility in cells, novel DNA- and RNA-based drug therapies, and rare cancers caused by errors in metabolism.
Georges Mer, Ph.D. NMR and chromatography
Metabolomics Nuclear Magnetic Resonance Spectroscopy Core
Provides an NMRS-based dynamic metabolomic platform for untargeted and targeted quantification of metabolite levels and measurement of fluxes within metabolic networks in human and transgenic animal biofluids.
Sanjay Misra, M.D. Tour of mouse surgical area
Vascular and Interventional Radiology Lab
Studies multiple different animal models in order to improve outcomes in patients with end-stage renal disease by developing novel therapies that can be delivered by image-guided intervention.
Tamas Ordog, M.D. Gastroenterology Researchers are studying the molecular, cellular and translational biology of the gastrointestinal neuromuscular system, with particular focus on interstitial cells of Cajal (ICC).
Kaylan S. Pasupathy, Ph.D. Clinical engineering
Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery
Researchers are focused on increasing the understanding of complex systems at the intersection of people, processes and information to improve patient care experience and population health. The team leads clinical engineering learning laboratories and directs studies to improve quality of care delivery though operations research, informatics and human factors.
Y.S. Prakash, M.D., Ph.D. Lung physiology and asthma
Pulmonary Cell Biology
Researchers and clinicians from multiple disciplines (anesthesiology, physiology, pulmonary medicine and neonatology) study mechanisms that regulate the structure and function of airways and pulmonary arteries, focusing on mechanisms that trigger and regulate physiological and pathological processes in the lung.
Stephen J. Riederer, Ph.D. MRI demonstration
Magnetic Resonance Lab
Development of new image acquisition methods based on MRI physics. Human studies are done in collaboration with radiologists and other medical specialists in the areas of cardiovascular, neurological and cancer imaging.
Lindsey R. Sangaralingham, M.P.H. Data visualization
OptumLabs
OptumLabs provides a research environment — including technology, tools, collaboration space and operating processes — and a translation network to assist in translating knowledge to changes in practice and policy. Core linked data assets include de-identified claims data for privately insured and Medicare Advantage enrollees and de-identified electronic health record (EHR) data from a nationwide network of provider groups.
Gary C. Sieck, Ph.D. Confocal imaging and ventilation
Cell and Regenerative Physiology Lab
Investigates the neural control and adaptation of breathing muscles. Focus areas include research on the diaphragm muscle, aging and respiratory muscle sarcopenia, spinal cord injury, and airway smooth muscle.
Ravinder J. Singh, Ph.D. Dilution and pipetting
Immunochemical Core
Provides immunochemical, chemistry and immune testing at an affordable cost to clinical and basic science researchers.
David I. Smith, Ph.D. Next Gen. Seq. Facility Lab/DNA "necklace"
Medical Genome Facility
Gives clinicians and researchers detailed information about the genetic makeup of their samples, allowing them to identify and characterize the role of genetics in disease and treatment.
George Vasmatzis, Ph.D. Biomarkers
Biomarker Discovery Program in the Center for Individualized Medicine
Researchers are focused on discovery and translation of several biomarkers and developing evidence-based models to help clinicians stratify patients with cancer in order to provide each individual with the appropriate care. With the recent advances in next-generation sequencing technologies, researchers have become engaged in massive sequencing to scan the genome of cancer cells for abnormalities that can be used for clinical purposes such as diagnosis and stratification of patients for optimal treatment.
Liewei Wang, M.D., Ph.D. Pharmacogenomics
Pharmacogenomics and Drug Targets
The team studies the role of inheritance in variation in drug response using various high-throughput "omics" tools, including genomics, transcriptomics and metabolomics, to identify biomarkers that can help predict clinical response. Researchers also use models, including cells, patient-derived xenografts and patient samples, to validate and understand the biology underlying these biomarkers.
Anthony J. Windebank, M.D. Chemo-induced peripheral neuropathy
Regenerative Neurobiology Lab
Research strives to understand the cellular mechanisms underlying injury and repair in the nervous system.