Publications

1. Kara F, Joers JM, Przybelski SA, Algeciras-Schimnich A, Gunter JL, Jack CR Jr, Petersen RC, Oz G, Kantarci K. (1)H-MR spectroscopy biomarkers are associated with plasma-derived biomarkers of amyloid-beta and tau in the early phase of AD continuum. Neurobiol Aging. 2026 Feb; 158:18-27 Epub 2025 Nov 10
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2. Kantarci K, Kara F, Tosakulwong N, Fought AJ, Schwarz CG, Senjem ML, Kendall-Thomas J, Min P, Lowe VJ, Jack CR, Kapoor E, Fields JA, Bailey KR, James TT, Faubion L, Lobo RA, Manson JE, Pal L, Hammers DB, Brinton EA, Malek-Ahmadi M, Cedars MI, Naftolin FN, Santoro N, Miller VM, Harman SM, Dowling NM, Gleason CE. Long-term amyloid PET and MRI outcomes in a menopausal hormone therapy trial. Alzheimers Dement. 2026 Feb; 22 (2):e71067
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3. James TT, Dowling NM, Ferrer Simo C, Salazar H, Van Hulle CA, Ennis G, Johnson AL, Wyman MF, McLester-Davis LWY, Gooding DC, Fischer B, Bouges S, Umucu E, Kara F, Kling JM, Manson JE, Brinton EA, Cedars MI, Lobo RA, Neal-Perry G, Santoro NF, Naftolin F, Harman SM, Pal L, Miller VM, Kantarci K, Gleason CE. Association between central adiposity and cognitive domain function in recently postmenopausal women: an analysis from the KEEPS-Cog substudy of the Kronos Early Estrogen Preventive Study. Menopause. 2026 Feb 1; 33 (2):151-160 Epub 2026 Feb 01
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4. Kara F, Neyal N, Kamykowski MG, Schwarz CG, Kendall-Thomas J, Morrison HA, Senjem ML, Przybelski SA, Fought AJ, Port JD, Deelchand DK, Lowe VJ, Oz G, Kantarci K, Kantarci OH, Zeydan B. Decoding Thalamic Glial Interplay in Multiple Sclerosis Through Proton Magnetic Resonance Spectroscopy and Positron Emission Tomography. Int J Mol Sci. 2025 Sep 5; 26 (17) Epub 2025 Sept 05
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5. Faubion LL, Mak E, Kara F, Tosakulwong N, Lesnick TG, Fought AJ, Reid RI, Schwarz CG, Kendall-Thomas J, Kapoor E, Fields JA, Bailey KR, James TT, Lobo RA, Manson JE, Pal L, Hammers DB, Brinton EA, Malek-Ahmadi M, Cedars M, Naftolin FN, Santoro N, Miller VM, Harman SM, Dowling NM, Gleason CE, Kantarci K. Long-term effects of 4 years of menopausal hormone therapy on white matter integrity. Menopause. 2025 Jul 22; 32 (9):818-28 Epub 2025 July 22
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6. Kara F, Tosakulwong N, Lesnick TG, Fought AJ, Kendell-Thomas J, Kapoor E, Faubion LL, Schwarz CG, Senjem ML, Fields JA, Min PH, Lowe VJ, Jack CR Jr, Bailey KR, James TT, Lobo RA, Manson JE, Pal L, Hammers DB, Malek-Ahmadi M, Cedars MI, Naftolin FN, Santoro N, Miller VM, Harman SM, Dowling NM, Gleason CE, Kantarci K. Associations of blood pressure with white matter hyperintensities later in life; influence of short-term menopausal hormone therapy. Menopause. 2025 Jan 1; 32 (1):12-22
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7. Kantarci K, Kapoor E, Geske JR, Castillo A, Fields JA, Kara F, Knyazhanskaya EE, Schwarz CG, Senjem ML, Bailey KR, Lowe V, LeBrasseur NK, Rocca WA, Mielke MM. Premenopausal bilateral oophorectomy and Alzheimer's disease imaging biomarkers later in life. Alzheimers Dement. 2024 Dec 23 [Epub ahead of print]
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8. Gleason CE, Dowling NM, Kara F, James TT, Salazar H, Ferrer Simo CA, Harman SM, Manson JE, Hammers DB, Naftolin FN, Pal L, Miller VM, Cedars MI, Lobo RA, Malek-Ahmadi M, Kantarci K. Long-term cognitive effects of menopausal hormone therapy: Findings from the KEEPS Continuation Study. PLoS Med. 2024 Nov; 21 (11):e1004435 Epub 2024 Nov 21
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9. Kara F, Kantarci K. Understanding Proton Magnetic Resonance Spectroscopy Neurochemical Changes Using Alzheimer's Disease Biofluid, PET, Postmortem Pathology Biomarkers, and APOE Genotype. Int J Mol Sci. 2024 Sep 19; 25 (18) Epub 2024 Sept 19
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10. Mielke MM, Frank RD, Christenson LR, Reid RI, Fields JA, Knyazhanskaya ZE, Kara F, Vemuri P, Rocca WA, Kantarci K. Premenopausal bilateral oophorectomy and brain white matter brain integrity in later-life. Alzheimers Dement. 2024 Jul; 20 (7):5054-5061 Epub 2024 June 20
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11. Warner NS, Hanson AC, Schulte PJ, Kara F, Reid RI, Schwarz CG, Benarroch EE, Graff-Radford J, Vemuri P, Jack CR, Petersen RC, Warner DO, Mielke MM, Kantarci K. Prescription Opioids and Brain Structure in Community-Dwelling Older Adults. Mayo Clin Proc. 2024 May; 99 (5):716-726
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12. Kantarci K, Tosakulwong N, Lesnick TG, Kara F, Kendall-Thomas J, Kapoor E, Fields JA, James TT, Lobo RA, Manson JE, Pal L, Hammers DB, Malek-Ahmadi M, Cedars MI, Naftolin FN, Santoro N, Miller VM, Harman SM, Dowling NM, Gleason CE. Cardiometabolic outcomes in Kronos Early Estrogen Prevention Study continuation: 14-year follow-up of a hormone therapy trial. Menopause. 2024 Jan 1; 31 (1):10-17 Epub 2023 Nov 21
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13. Beyer J, Couch R, Ruddy KJ, Zeydan B, Tosakulwong N, Lesnick TG, Novotny PJ, Kohli S, Cerhan JH, Pruthi S, Kantarci K, Kara F. Longitudinal cognitive function and brain metabolites in women receiving chemotherapy for stage 1 to 3 breast cancer: Observational study. Medicine (Baltimore). 2023 Oct 20; 102 (42):e35524
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14. Kara F, Lohse CM, Castillo AM, Tosakulwong N, Lesnick TG, Jack CR Jr, Petersen RC, Olson JE, Couch FJ, Ruddy KJ, Kantarci K, Mielke MM. Association of raloxifene and tamoxifen therapy with cognitive performance, odds of mild cognitive impairment, and brain MRI markers of neurodegeneration. Cancer Med. 2023 Feb; 12 (3):2805-2817 Epub 2022 Aug 30
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15. Deelchand DK, Henry PG, Joers JM, Auerbach EJ, Park YW, Kara F, Ratai EM, Kantarci K, Oz G. Plug-and-play advanced magnetic resonance spectroscopy. Magn Reson Med. 2022 Jun; 87 (6):2613-2620 Epub 2022 Jan 28
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16. Kara F, Joers JM, Deelchand DK, Park YW, Przybelski SA, Lesnick TG, Senjem ML, Zeydan B, Knopman DS, Lowe VJ, Vemuri P, Mielke MM, Machulda MM, Jack CR, Petersen RC, Oz G, Kantarci K. (1)H MR spectroscopy biomarkers of neuronal and synaptic function are associated with tau deposition in cognitively unimpaired older adults. Neurobiol Aging. 2022 Apr; 112:16-26 Epub 2022 Jan 05
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17. Kara F, Belloy ME, Voncken R, Sarwari Z, Garima Y, Anckaerts C, Langbeen A, Leysen V, Shah D, Jacobs J, Hamaide J, Bols P, Van Audekerke J, Daans J, Guglielmetti C, Kantarci K, Prevot V, Rossner S, Ponsaerts P, Van der Linden A, Verhoye M. Long-term ovarian hormone deprivation alters functional connectivity, brain neurochemical profile and white matter integrity in the Tg2576 amyloid mouse model of Alzheimer's disease. Neurobiol Aging. 2021 Jun; 102:139-150 Epub 2021 Feb 22
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18. Lanz B, Abaei A, Braissant O, Choi IY, Cudalbu C, Henry PG, Gruetter R, Kara F, Kantarci K, Lee P, Lutz NW, Marjanska M, Mlynarik V, Rasche V, Xin L, Valette J, Experts' Working Group on Magnetic resonance spectroscopy in the rodent brain//Experts' Working Group on Magnetic resonance spectroscopy in the rodent brain. Magnetic resonance spectroscopy in the rodent brain: Experts' consensus recommendations. NMR Biomed. 2020 Aug 26; e4325 [Epub ahead of print]
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19. Servaes S, Kara F, Glorie D, Stroobants S, Van Der Linden A, Staelens S. In Vivo Preclinical Molecular Imaging of Repeated Exposure to an N-methyl-d-aspartate Antagonist and a Glutaminase Inhibitor as Potential Glutamatergic Modulators. J Pharmacol Exp Ther. 2019 Mar; 368 (3):382-390 Epub 2018 Dec 14
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20. Mannheim JG, Kara F, Doorduin J, Fuchs K, Reischl G, Liang S, Verhoye M, Gremse F, Mezzanotte L, Huisman MC. Standardization of Small Animal Imaging-Current Status and Future Prospects. Mol Imaging Biol. 2018 Oct; 20 (5):716-731
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21. Guglielmetti C, Le Blon D, Santermans E, Salas-Perdomo A, Daans J, De Vocht N, Shah D, Hoornaert C, Praet J, Peerlings J, Kara F, Bigot C, Mai Z, Goossens H, Hens N, Hendrix S, Verhoye M, Planas AM, Berneman Z, van der Linden A, Ponsaerts P. Interleukin-13 immune gene therapy prevents CNS inflammation and demyelination via alternative activation of microglia and macrophages. Glia. 2016 Dec; 64 (12):2181-2200 Epub 2016 Sept 29
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22. Shah D, Blockx I, Keliris GA, Kara F, Jonckers E, Verhoye M, Van der Linden A. Cholinergic and serotonergic modulations differentially affect large-scale functional networks in the mouse brain. Brain Struct Funct. 2016 Jul; 221 (6):3067-79 Epub 2015 July 21
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23. Orije J, Kara F, Guglielmetti C, Praet J, Van der Linden A, Ponsaerts P, Verhoye M. Longitudinal monitoring of metabolic alterations in cuprizone mouse model of multiple sclerosis using 1H-magnetic resonance spectroscopy. Neuroimage. 2015 Jul 1; 114:128-35 Epub 2015 Apr 11
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24. Praet J, Orije J, Kara F, Guglielmetti C, Santermans E, Daans J, Hens N, Verhoye M, Berneman Z, Ponsaerts P, Van der Linden A. Cuprizone-induced demyelination and demyelination-associated inflammation result in different proton magnetic resonance metabolite spectra. NMR Biomed. 2015 Apr; 28 (4):505-13
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25. Kara F, Hofling C, Rossner S, Schliebs R, Van der Linden A, Groot HJ, Alia A. In Vivo Longitudinal Monitoring of Changes in the Corpus Callosum Integrity During Disease Progression in a Mouse Model of Alzheimer's Disease. Curr Alzheimer Res. 2015; 12 (10):941-50
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26. Kara F, Chen F, Ronen I, de Groot HJ, Matysik J, Alia A. In vivo measurement of transverse relaxation time in the mouse brain at 17.6 T. Magn Reson Med. 2013 Oct; 70 (4):985-93 Epub 2012 Nov 14
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27. Kara F, Dongen ES, Schliebs R, Buchem MA, Groot HJ, Alia A. Monitoring blood flow alterations in the Tg2576 mouse model of Alzheimer's disease by in vivo magnetic resonance angiography at 17.6 T. Neuroimage. 2012 Apr 2; 60 (2):958-66 Epub 2011 Dec 29
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28. Haud N, Kara F, Diekmann S, Henneke M, Willer JR, Hillwig MS, Gregg RG, Macintosh GC, Gartner J, Alia A, Hurlstone AF. rnaset2 mutant zebrafish model familial cystic leukoencephalopathy and reveal a role for RNase T2 in degrading ribosomal RNA. Proc Natl Acad Sci U S A. 2011 Jan 18; 108 (3):1099-103 Epub 2011 Jan 03
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29. Jakubowska-Dogru E, Gumusbas U, Kara F. Individual variation in the spatial reference and working memory assessed under allothetic and idiothetic orientation cues in rat. Acta Neurobiol Exp (Wars). 2003; 63 (1):17-23
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