Publications

  1. Rabinowitz LG, Grinspan LT, Zylberberg HM, Dixon R, David YN, Aroniadis OC, Chiang A, Christie J, Fayad NF, Ha C, Harris LA, Ko CW, Kolb J, Kwah J, Lee L, Lieberman D, Raffals LE, Rex DK, Shah SC, Siddiqui UD, Smith MS, Wallace M, Williams R, Woods K, Crowe SE, Kumta NA, Kim MK, Greenwald DA. Survey Finds Gender Disparities Impact Both Women Mentors and Mentees in Gastroenterology. Am J Gastroenterol. 2021 Jun 18 Epub 2021 June 18
    View PubMed
  2. Braga Neto MB, Ramos GP, Loftus EV Jr, Faubion WA, Raffals LE. Use of Immune Checkpoint Inhibitors in Patients With Pre-established Inflammatory Bowel Diseases: Retrospective Case Series. Clin Gastroenterol Hepatol. 2021 Jun; 19 (6):1285-1287.e1 Epub 2020 June 19
    View PubMed
  3. Lui J, Ramos GP, Codipilly DC, Katzka D, Raffals LE. The Use of Biologics for the Treatment of Esophageal Crohn Disease. Inflamm Bowel Dis. 2021 May 29 [Epub ahead of print]
    View PubMed
  4. Kamboj AK, Chandrasekhara V, Simonetto DA, Raffals LE. How We Did It: Virtual Interviews With an Eye Toward the Future. Am J Gastroenterol. 2021 May 19 [Epub ahead of print]
    View PubMed
  5. Coelho-Prabhu N, Bruining DH, Faubion WA, Kane SV, Kisiel JB, Papadakis KA, Pardi DS, Raffals LE, Schroeder KW, Tremaine WJ, Fruth K, Harmsen WS, Loftus EV. A 1-Year Cross-sectional Inflammatory Bowel Disease Surveillance Colonoscopy Cohort Comparing High-definition White Light Endoscopy and Chromoendoscopy. Inflamm Bowel Dis. 2021 Apr 15; 27 (5):594-602
    View PubMed
  6. Abd El Aziz MA, Perry WRG, Grass F, Merchea A, Raffals LE, Mathis KL, Behm KT. The extent of colorectal resection and short-term outcomes in patients with ulcerative colitis. Updates Surg. 2021 Mar 30 [Epub ahead of print]
    View PubMed
  7. Wang MH, Friton JJ, Raffals LE, Leighton JA, Pasha SF, Picco MF, Monroe K, Nix BD, Newberry RD, Faubion WA. Novel Genetic Variant Predicts Surgical Recurrence Risk in Crohn's Disease Patients. Inflamm Bowel Dis. 2021 Mar 16 [Epub ahead of print]
    View PubMed
  8. Kwapisz L, Raffals LE, Bruining DH, Pardi DS, Tremaine WJ, Kane SV, Papadakis KA, Coelho-Prabhu N, Kisiel JB, Heron V, Faubion WA, Loftus EV Jr. Combination Biologic Therapy in Inflammatory Bowel Disease: Experience From a Tertiary Care Center. Clin Gastroenterol Hepatol. 2021 Mar; 19 (3):616-617 Epub 2020 Feb 14
    View PubMed
  9. Quinn KP, Urquhart SA, Janssens LP, Lennon RJ, Chedid VG, Raffals LE. Primary Sclerosing Cholangitis-Associated Pouchitis: A Distinct Clinical Phenotype. Clin Gastroenterol Hepatol. 2021 Feb 4 Epub 2021 Feb 04
    View PubMed
  10. Ramos GP, Dimopoulos C, McDonald NM, Janssens LP, Hung KW, Proctor D, Ruggiero E, Kane S, Bruining DH, Faubion WA, Raffals LE, Loftus EV, Al-Bawardy B. The Impact of Vedolizumab on Pre-Existing Extraintestinal Manifestations of Inflammatory Bowel Disease: A Multicenter Study. Inflamm Bowel Dis. 2020 Nov 9 Epub 2020 Nov 09
    View PubMed
  11. Dulai PS, Raffals LE, Hudesman D, Chiorean M, Cross R, Ahmed T, Winter M, Chang S, Fudman D, Sadler C, Chiu EL, Ross FL, Toups G, Murad MH, Sethuraman K, Holm JR, Guilliod R, Levine B, Buckey JC Jr, Siegel CA. A phase 2B randomised trial of hyperbaric oxygen therapy for ulcerative colitis patients hospitalised for moderate to severe flares. Aliment Pharmacol Ther. 2020 Sep; 52 (6):955-963 Epub 2020 Aug 03
    View PubMed
  12. Quinn KP, Raffals LE. An Update on the Medical Management of Inflammatory Pouch Complications. Am J Gastroenterol. 2020 Sep; 115 (9):1439-1450
    View PubMed
  13. Cohen BL, Gallinger ZR, Ha C, Holubar SD, Hou JK, Kinnucan J, Mahadevan U, Moss AC, Raffals LE, Regueiro M, Szigethy E, Wolf D, Dubinsky MC, Patel A, Shah BJ, Ehrlich OG, Hanauer SB. Development of Entrustable Professional Activities for Advanced Inflammatory Bowel Disease Fellowship Training in the United States. Inflamm Bowel Dis. 2020 Aug 20; 26 (9):1291-1305
    View PubMed
  14. Bies M, Vijayvargiya P, Raffals L. Submucosal Vascular Malformation as the Cause of Recurrent Obscure Bleed. Clin Gastroenterol Hepatol. 2020 Aug; 18 (9):e106 Epub 2019 May 14
    View PubMed
  15. Barnes EL, Raffals L, Long MD, Syal G, Kayal M, Ananthakrishnan A, Cohen B, Pekow J, Deepak P, Colombel JF, Herfarth HH, Sandler RS. Disease and Treatment Patterns Among Patients With Pouch-related Conditions in a Cohort of Large Tertiary Care Inflammatory Bowel Disease Centers in the United States. Crohns Colitis 360. 2020 Jul; 2 (3):otaa039 Epub 2020 July 24
    View PubMed
  16. Braga Neto MB, Gregory MH, Ramos GP, Bazerbachi F, Bruining DH, Abu Dayyeh BK, Kushnir VM, Raffals LE, Ciorba MA, Loftus EV, Deepak P. Impact of Bariatric Surgery on the Long-term Disease Course of Inflammatory Bowel Disease. Inflamm Bowel Dis. 2020 Jun 18; 26 (7):1089-1097
    View PubMed
  17. Rajan E, Martinez M, Gorospe E, Al Bawardy B, Dobashi A, Mara KC, Hansel SL, Bruining DH, Murray JA, Leggett CL, Nehra V, Iyer PG, Pasha SF, Leighton JA, Shiff AD, Gurudu SR, Raffals LE, Lavey C, Katzka DA, Chen CH. Prospective multicenter study to evaluate capsule endoscopy competency using a validated assessment tool. Gastrointest Endosc. 2020 May; 91 (5):1140-1145 Epub 2019 Dec 26
    View PubMed
  18. Wang MH, Mousa OY, Friton JJ, Raffals LE, Leighton JA, Pasha SF, Picco MF, Cushing KC, Monroe K, Nix BD, Newberry RD, Faubion WA. Unique Phenotypic Characteristics and Clinical Course in Patients With Ulcerative Colitis and Primary Sclerosing Cholangitis: A Multicenter US Experience. Inflamm Bowel Dis. 2020 Apr 11; 26 (5):774-779
    View PubMed
  19. Eckmann JD, Chedid V, Quinn KP, Bonthu N, Nehra V, Raffals LE. De Novo Colitis Associated With Rituximab in 21 Patients at a Tertiary Center. Clin Gastroenterol Hepatol 2020 Jan; 18 (1):252-253 Epub 2019 Mar 21
    View PubMed
  20. Jawoosh M, Haffar S, Deepak P, Meyers A, Lightner AL, Larson DW, Raffals LH, Murad MH, Buttar N, Bazerbachi F. Volvulus of the ileal pouch-anal anastomosis: a meta-narrative systematic review of frequency, diagnosis, and treatment outcomes. Gastroenterol Rep (Oxf). 2019 Dec; 7 (6):403-410 Epub 2019 Sept 17
    View PubMed
  21. Park SH, Al-Bawardy B, Aniwan S, Kane SV, Coelho-Prabhu N, Papadakis KA, Kisiel JB, Bruining DH, Faubion WA, Raffals LE, Pardi DS, Tremaine WJ, Stephens MC, Tung J, Khanna S, Willrich, Loftus EV. Distinct cutoff values of adalimumab trough levels are associated with different therapeutic outcomes in patients with inflammatory bowel disease. Crohn's & Colitis 360. 2019; 1(3):otz047.
  22. Lightner AL, McKenna NP, Alsughayer A, Harmsen WS, Taparra K, Parker ME, Raffals LE, Loftus EV Jr. Biologics and 30-Day Postoperative Complications After Abdominal Operations for Crohn's Disease: Are There Differences in the Safety Profiles? Dis Colon Rectum. 2019 Nov; 62 (11):1352-1362
    View PubMed
  23. Lightner AL, McKenna NP, Alsughayer A, Loftus EV Jr, Raffals LE, Faubion WA, Moir C. Anti-TNF biologic therapy does not increase postoperative morbidity in pediatric Crohn's patients. J Pediatr Surg. 2019 Oct; 54 (10):2162-2165 Epub 2019 Jan 18
    View PubMed
  24. Wang , Mousa OY, Friton JJ, Raffals LE, Leighton JA, Pasha SF, Picco MF, Cushing KC, Monroe K, Nix BD, Newberry RD, Faubion WA. Unique Phenotypic Characteristics and Clinical Course in Patients With Ulcerative Colitis and Primary Inflamm Bowel Dis. 2019.
  25. Gregory M, Weaver KN, Hoversten P, Hicks SB, Patel D, Ciorba MA, Gutierrez AM, Beniwal-Patel P, Palam S, Syal G, Herfarth HH, Christophi G, Raffals L, Barnes EL, Deepak P. Efficacy of Vedolizumab for Refractory Pouchitis of the Ileo-anal Pouch: Results From a Multicenter US Cohort. Inflamm Bowel Dis. 2019 Aug 20; 25 (9):1569-1576
    View PubMed
  26. Quinn KP, Prothero BL, Russell JM, Hegge RJ, von AG, Larson PA, Christofferson SN, Smyrk TC, Mathis KL, Goenka AH, Sheedy SP, Bruining DH, Fletcher JG, Loftus EV, Raffals LE. Impact of multidisciplinary eBoard on the management of patients with complex inflammatory bowel disease. Crohn's & Colitis 360. 2019; 1(2):otz013.
  27. Lightner AL, Grass F, Alsughayer A, Petersen MM, Raffals LE, Loftus EV. Postoperative outcomes in ustekinumab-treated patients undergoing abdominal operations for Crohn's disease: single-center series. Crohn's & Colitis 360. 2019; 1(2):otz018.
  28. Wang MH, Friton JJ, Raffals LE, Leighton JA, Pasha SF, Picco MF, Cushing KC, Monroe K, Nix BD, Newberry RD, Faubion WA. Novel Genetic Risk Variants Can Predict Anti-TNF Agent Response in Patients With Inflammatory Bowel Disease. J Crohns Colitis. 2019 Aug 14; 13 (8):1036-1043
    View PubMed
  29. Aniwan S, Bruining DH, Park SH, Al-Bawardy B, Kane SV, Coelho Prabhu N, Kisiel JB, Raffals LE, Papadakis KA, Pardi DS, Tremaine WJ, Loftus EV Jr. The Combination of Patient-Reported Clinical Symptoms and an Endoscopic Score Correlates Well with Health-Related Quality of Life in Patients with Ulcerative Colitis. J Clin Med. 2019 Aug 5; 8 (8) Epub 2019 Aug 05
    View PubMed
  30. Papamichael K, Cheifetz AS, Melmed GY, Irving PM, Vande Casteele N, Kozuch PL, Raffals LE, Baidoo L, Bressler B, Devlin SM, Jones J, Kaplan GG, Sparrow MP, Velayos FS, Ullman T, Siegel CA. Appropriate Therapeutic Drug Monitoring of Biologic Agents for Patients With Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol 2019 Aug; 17 (9):1655-1668.e3 Epub 2019 Mar 27
    View PubMed
  31. Sparrow MP, Melmed GY, Devlin S, Kozuch P, Raffals L, Loftus EV Jr, Rubin DT, Spiegel B, Baidoo L, Bressler B, Cheifetz A, Irving P, Jones J, Kaplan GG, Velayos F, Siegel CA. De-escalating medical therapy in Crohn's disease patients who are in deep remission: a RAND appropriateness panel GastroHep. 2019; 1(3):108-117.
  32. Muniz Pedrogo DA, Chen J, Hillmann B, Jeraldo P, Al-Ghalith G, Taneja V, Davis JM 3rd, Knights D, Nelson H, Faubion WA, Raffals L, Kashyap PC. An Increased Abundance of Clostridiaceae Characterizes Arthritis in Inflammatory Bowel Disease and Rheumatoid Arthritis: A Cross-sectional Study. Inflamm Bowel Dis. 2019 Apr 11; 25 (5):902-913
    View PubMed
  33. Raffals LE, Nguyen GC, Rubin DT. Switching Between Biologics and Biosimilars in Inflammatory Bowel Disease. Clin Gastroenterol Hepatol. 2019 Apr; 17 (5):818-823 Epub 2018 Sept 07
    View PubMed
  34. Weaver KN, Gregory M, Syal G, Hoversten P, Hicks SB, Patel D, Christophi G, Beniwal-Patel P, Isaacs KL, Raffals L, Deepak P, Herfarth HH, Barnes EL. Ustekinumab Is Effective for the Treatment of Crohn's Disease of the Pouch in a Multicenter Cohort. Inflamm Bowel Dis. 2019 Mar 14; 25 (4):767-774
    View PubMed
  35. Al-Bawardy B, Ramos GP, Willrich MAV, Jenkins SM, Park SH, Aniwan S, Schoenoff SA, Bruining DH, Papadakis KA, Raffals L, Tremaine WJ, Loftus EV. Vedolizumab Drug Level Correlation With Clinical Remission, Biomarker Normalization, and Mucosal Healing in Inflammatory Bowel Disease. Inflamm Bowel Dis. 2019 Feb 21; 25 (3):580-586
    View PubMed
  36. Quinn KP, Lightner AL, Faubion WA, Raffals LE. A Comprehensive Approach to Pouch Disorders. Inflamm Bowel Dis. 2019 Feb 21; 25 (3):460-471
    View PubMed
  37. Lightner AL, Edward V Loftus Jr Loftus, Loftus EV, McKenna NP, Raffals LE. Vedolizumab in the Perioperative Management of Inflammatory Bowel Disease. Curr Drug Targets. 2019; 20 (13):1317-1322
    View PubMed
  38. Ichikawa R, Lamb CA, Eastham-Anderson J, Scherl A, Raffals L, Faubion WA, Bennett MR, Long AK, Mansfield JC, Kirby JA, Keir ME. AlphaE Integrin Expression Is Increased in the Ileum Relative to the Colon and Unaffected by Inflammation. J Crohns Colitis. 2018 Nov 9; 12 (10):1191-1199
    View PubMed
  39. Melmed GY, Kaplan GG, Sparrow MP, Velayos FS, Baidoo L, Bressler B, Cheifetz AS, Devlin SM, Irving PM, Jones J, Kozuch PL, Raffals LE, Siegel CA. Appropriateness of Combination Therapy for Patients With Inflammatory Bowel Diseases: One Size Still Does Not Fit All. Clin Gastroenterol Hepatol. 2018 Nov; 16 (11):1829-1831 Epub 2018 Mar 02
    View PubMed
  40. Dulai PS, Buckey JC Jr, Raffals LE, Swoger JM, Claus PL, O'Toole K, Ptak JA, Gleeson MW, Widjaja CE, Chang JT, Adler JM, Patel N, Skinner LA, Haren SP, Goldby-Reffner K, Thompson KD, Siegel CA. Hyperbaric oxygen therapy is well tolerated and effective for ulcerative colitis patients hospitalized for moderate-severe flares: a phase 2A pilot multi-center, randomized, double-blind, sham-controlled trial. Am J Gastroenterol. 2018 Oct; 113 (10):1516-1523 Epub 2018 Feb 16
    View PubMed
  41. Malikowski T, Mahmood M, Smyrk T, Raffals L, Nehra V. Tuberculosis of the gastrointestinal tract and associated viscera. J Clin Tuberc Other Mycobact Dis. 2018 Aug; 12:1-8 Epub 2018 Apr 14
    View PubMed
  42. Tse CS, Loftus EV Jr, Raffals LE, Gossard AA, Lightner AL. Effects of vedolizumab, adalimumab and infliximab on biliary inflammation in individuals with primary sclerosing cholangitis and inflammatory bowel disease. Aliment Pharmacol Ther. 2018 Jul; 48 (2):190-195 Epub 2018 May 28
    View PubMed
  43. Hansel SL, McCurdy JD, Barlow JM, Fidler J, Fletcher JG, Becker B, Prabhu NC, Faubion WA, Hanson KA, Kane SV, Kisiel JB, Loftus EV Jr, Papadakis KA, Pardi DS, Raffals LE, Schoenoff S, Tremaine WJ, Bruining DH. Clinical Benefit of Capsule Endoscopy in Crohn's Disease: Impact on Patient Management and Prevalence of Proximal Small Bowel Involvement. Inflamm Bowel Dis. 2018 Jun 8; 24 (7):1582-1588
    View PubMed
  44. Patel P, Yarur A, Dalal S, Sakuraba A, Rubin DT, Hanauer SB, Hanan I, Raffals LH, Cohen RD, Pekow J. Clinical Response and Complications are not Associated with Drug Levels in Patients with Severe Ulcerative Colitis on IV Cyclosporine Induction Therapy. Inflamm Bowel Dis. 2018 May 18; 24 (6):1291-1297
    View PubMed
  45. Mouchli MA, Singh S, Boardman L, Bruining DH, Lightner AL, Rosen CB, Heimbach JK, Hasan B, Poterucha JJ, Watt KD, Kane SV, Raffals LE, Loftus EV. Natural History of Established and De Novo Inflammatory Bowel Disease After Liver Transplantation for Primary Sclerosing Cholangitis. Inflamm Bowel Dis. 2018 Apr 23; 24 (5):1074-1081
    View PubMed
  46. Hanada Y, Khanna S, Loftus EV Jr, Raffals LE, Pardi DS. Non-Clostridium difficile Bacterial Infections Are Rare in Patients With Flares of Inflammatory Bowel Disease. Clin Gastroenterol Hepatol. 2018 Apr; 16 (4):528-533 Epub 2017 Oct 14
    View PubMed
  47. Lightner AL, McKenna NP, Tse CS, Hyman N, Smith R, Ovsepyan G, Fleshner P, Crowell K, Koltun W, Ferrante M, D'Hoore A, Lauwers N, Verstockt B, Spinelli A, DiCandido F, Raffals LE, Mathis KL, Loftus EV Jr. Postoperative Outcomes in Ustekinumab-Treated Patients Undergoing Abdominal Operations for Crohn's Disease. J Crohns Colitis. 2018 Mar 28; 12 (4):402-407
    View PubMed
  48. Braga Neto MB, Gregory M, Ramos GP, Piovezani Ramos G, Loftus EV Jr, Ciorba MA, Bruining DH, Bazerbachi F, Abu Dayyeh BK, Kushnir VM, Shah M, Collazo-Clavell ML, Raffals LE, Deepak P. De-novo Inflammatory Bowel Disease After Bariatric Surgery: A Large Case Series. J Crohns Colitis. 2018 Mar 28; 12 (4):452-457
    View PubMed
  49. Lightner AL, McKenna NP, Tse CS, Raffals LE, Loftus EV Jr, Mathis KL. Postoperative outcomes in vedolizumab-treated Crohn's disease patients undergoing major abdominal operations. Aliment Pharmacol Ther. 2018 Mar; 47 (5):573-580 Epub 2017 Dec 18
    View PubMed
  50. Aniwan S, Tremaine WJ, Raffals LE, Kane SV, Loftus EV. Antibiotic Use and New-Onset Inflammatory Bowel Disease in Olmsted County, Minnesota: A Population-Based Case-Control Study. J Crohns Colitis. 2018 Jan 24; 12 (2):137-144
    View PubMed
  51. Kotze PG, Ma C, Mckenna N, Almutairdi A, Kaplan GG, Raffals LE, Loftus EV Jr, Panaccione R, Lightner AL. Vedolizumab and early postoperative complications in nonintestinal surgery: a case-matched analysis. Therap Adv Gastroenterol. 2018; 11:1756284818783614 Epub 2018 June 21
    View PubMed
  52. Kochar B, Barnes EL, Long MD, Cushing KC, Galanko J, Martin CF, Raffals LE, Sandler RS. Depression Is Associated With More Aggressive Inflammatory Bowel Disease. Am J Gastroenterol. 2018 Jan; 113 (1):80-85 Epub 2017 Nov 14
    View PubMed
  53. Tse CS, Deepak P, Smyrk TC, Raffals LE. Isolated Acute Terminal Ileitis Without Preexisting Inflammatory Bowel Disease Rarely Progresses to Crohn's Disease. Dig Dis Sci. 2017 Dec; 62 (12):3557-3562 Epub 2017 Oct 24
    View PubMed
  54. Lightner AL, McKenna NP, Moncrief S, Pemberton JH, Raffals LE, Mathis KL. Surgical Outcomes in Vedolizumab-Treated Patients with Ulcerative Colitis. Inflamm Bowel Dis. 2017 Dec; 23 (12):2197-2201
    View PubMed
  55. Lightner AL, Fletcher JG, Pemberton JH, Mathis KL, Raffals LE, Smyrk T. Crohn's Disease of the Pouch: A True Diagnosis or an Oversubscribed Diagnosis of Exclusion? Dis Colon Rectum. 2017 Nov; 60 (11):1201-1208
    View PubMed
  56. Khanna S, Raffals LE. The Microbiome in Crohn's Disease: Role in Pathogenesis and Role of Microbiome Replacement Therapies. Gastroenterol Clin North Am. 2017 Sep; 46 (3):481-492 Epub 2017 July 19
    View PubMed
  57. Quinn KP, Tse CS, Lightner AL, Pendegraft RS, Enders FT, Raffals LE. Nonrelaxing Pelvic Floor Dysfunction Is an Underestimated Complication of Ileal Pouch-Anal Anastomosis. Clin Gastroenterol Hepatol. 2017 Aug; 15 (8):1242-1247 Epub 2017 Mar 01
    View PubMed
  58. Kochar B, Long MD, Galanko J, Raffals LE, Ananthakrishnan A, Sandler RS. Inflammatory Bowel Disease is Similar in Patients with Older Onset and Younger Onset. Inflamm Bowel Dis. 2017 Jul; 23 (7):1187-1194
    View PubMed
  59. Lightner AL, Tse CS, Quinn K, Bergquist JR, Enders F, Pendegraft R, Khanna S, Raffals L. Preoperative Clostridium difficile Infection Does Not Affect Pouch Outcomes in Patients with Ulcerative Colitis Who Undergo Ileal Pouch-anal Anastomosis. Inflamm Bowel Dis. 2017 Jul; 23 (7):1195-1201
    View PubMed
  60. Ananthakrishnan AN, Sakuraba A, Barnes EL, Pekow J, Raffals L, Long MD, Sandler RS. The benefit of combination therapy depends on disease phenotype and duration in Crohn's disease. Aliment Pharmacol Ther. 2017 Jul; 46 (2):162-168 Epub 2017 May 03
    View PubMed
  61. Lightner AL, Mathis KL, Dozois EJ, Hahnsloser D, Loftus EV Jr, Raffals LE, Pemberton JH. Results at Up to 30 Years After Ileal Pouch-Anal Anastomosis for Chronic Ulcerative Colitis. Inflamm Bowel Dis. 2017 May; 23 (5):781-790
    View PubMed
  62. Huang Y, Dalal S, Antonopoulos D, Hubert N, Raffals LH, Dolan K, Weber C, Messer JS, Jabri B, Bendelac A, Eren AM, Rubin DT, Sogin M, Chang EB. Early Transcriptomic Changes in the Ileal Pouch Provide Insight into the Molecular Pathogenesis of Pouchitis and Ulcerative Colitis. Inflamm Bowel Dis. 2017 Mar; 23 (3):366-378
    View PubMed
  63. Lightner AL, Raffals LE, Mathis KL, Cima RR, Tse CS, Pemberton JH, Dozois EJ, Loftus EV. Postoperative Outcomes in Vedolizumab-Treated Patients Undergoing Abdominal Operations for Inflammatory Bowel Disease. J Crohns Colitis.2017 Feb;11:(2):185-190.
  64. Vineis JH, Ringus DL, Morrison HG, Delmont TO, Dalal S, Raffals LH, Antonopoulos DA, Rubin DT, Eren AM, Chang EB, Sogin ML. Patient-Specific Bacteroides Genome Variants in Pouchitis. mBio. 2016 Nov 15; 7 (6)
    View PubMed
  65. Kottschade L, Brys A, Peikert T, Ryder M, Raffals L, Brewer J, Mosca P, Markovic S, Midwest Melanoma Partnership. A multidisciplinary approach to toxicity management of modern immune checkpoint inhibitors in cancer therapy. Melanoma Res. 2016 Oct; 26 (5):469-80
    View PubMed
  66. Quinn KP, Lightner AL, Pendegraft RS, Enders FT, Boardman LA, Raffals LE. Pouchitis Is a Common Complication in Patients With Familial Adenomatous Polyposis Following Ileal Pouch-Anal Anastomosis. Clin Gastroenterol Hepatol. 2016 Sep; 14 (9):1296-301 Epub 2016 Apr 13
    View PubMed
  67. Melmed GY, Irving PM, Jones J, Kaplan GG, Kozuch PL, Velayos FS, Baidoo L, Sparrow MP, Bressler B, Cheifetz AS, Devlin SM, Raffals LE, Vande Casteele N, Mould DR, Colombel JF, Dubinsky M, Sandborn WJ, Siegel CA. Appropriateness of Testing for Anti-Tumor Necrosis Factor Agent and Antibody Concentrations, and Interpretation of Results. Clin Gastroenterol Hepatol. 2016 Sep; 14 (9):1302-9 Epub 2016 May 14
    View PubMed
  68. Raffals LE, Chang EB. Navigating the Microbial Basis of Inflammatory Bowel Diseases: Seeing the Light at the End of the Tunnel. Gut Liver. 2016 Jul 15; 10 (4):502-8
    View PubMed
  69. Devlin SM, Melmed GY, Irving PM, Rubin DT, Kornbluth A, Kozuch PL, Raffals LE, Velayos FS, Sparrow MP, Baidoo L, Bressler B, Cheifetz AS, Jones J, Kaplan GG, Siegel CA. Recommendations for Quality Colonoscopy Reporting for Patients with Inflammatory Bowel Disease: Results from a RAND Appropriateness Panel. Inflamm Bowel Dis 2016 Jun; 22 (6):1418-24
    View PubMed
  70. Ward MA, Pierre JF, Leal RF, Huang Y, Shogan B, Dalal SR, Weber CR, Leone VA, Musch MW, An GC, Rao MC, Rubin DT, Raffals LE, Antonopoulos DA, Sogin ML, Hyman NH, Alverdy JC, Chang EB. Insights into the pathogenesis of ulcerative colitis from a murine model of stasis-induced dysbiosis, colonic metaplasia, and genetic susceptibility. Am J Physiol Gastrointest Liver Physiol. 2016 Jun 1; 310 (11):G973-88 Epub 2016 Apr 14
    View PubMed
  71. Jones JL, Kaplan GG, Peyrin-Biroulet L, Baidoo L, Devlin S, Melmed GY, Tanyingoh D, Raffals L, Irving P, Kozuch P, Sparrow M, Velayos F, Bressler B, Cheifetz A, Colombel JF, Siegel CA. Effects of Concomitant Immunomodulator Therapy on Efficacy and Safety of Anti-Tumor Necrosis Factor Therapy for Crohn's Disease: A Meta-analysis of Placebo-controlled Trials. Clin Gastroenterol Hepatol. 2015 Dec; 13 (13):2233-40.e1-2; quiz e177-8 Epub 2015 June 30
    View PubMed
  72. De Felice KM, Katzka DA, Raffals LE. Crohn's Disease of the Esophagus: Clinical Features and Treatment Outcomes in the Biologic Era. Inflamm Bowel Dis. 2015 Sep; 21 (9):2106-13
    View PubMed
  73. De Felice KM, Gupta A, Rakshit S, Khanna S, Kottschade LA, Finnes HD, Papadakis KA, Loftus EV Jr, Raffals LE, Markovic SN. Ipilimumab-induced colitis in patients with metastatic melanoma. Melanoma Res. 2015 Aug; 25 (4):321-7
    View PubMed
  74. Ananthakrishnan AN, Kwon J, Raffals L, Sands B, Stenson WF, McGovern D, Kwon JH, Rheaume RL, Sandler RS. Variation in treatment of patients with inflammatory bowel diseases at major referral centers in the United States. Clin Gastroenterol Hepatol. 2015 Jun; 13 (6):1197-200 Epub 2014 Nov 21
    View PubMed
  75. Tabibian A, Tabibian JH, Beckman LJ, Raffals LL, Papadakis KA, Kane SV. Predictors of health-related quality of life and adherence in Crohn's disease and ulcerative colitis: implications for clinical management. Dig Dis Sci. 2015 May; 60 (5):1366-74 Epub 2015 Jan 06
    View PubMed
  76. De Felice KM, Novotna M, Enders FT, Faubion WA, Tremaine WJ, Kantarci OH, Raffals LE. Idiopathic inflammatory demyelinating disease of the central nervous system in patients with inflammatory bowel disease: retrospective analysis of 9095 patients. Aliment Pharmacol Ther. 2015 Jan; 41 (1):99-107 Epub 2014 Oct 27
    View PubMed
  77. Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, Baldwin CT, Jarvik GP, Crane PK, Rogaeva E, Barmada MM, Demirci FY, Cruchaga C, Kramer PL, Ertekin-Taner N, Hardy J, Graff-Radford NR, Green RC, Larson EB, St George-Hyslop PH, Buxbaum JD, Evans DA, Schneider JA, Lunetta KL, Kamboh MI, Saykin AJ, Reiman EM, De Jager PL, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Martin ER, Haines JL, Mayeux RP, Farrer LA, Schellenberg GD, Pericak-Vance MA, Albert MS, Albin RL, Apostolova LG, Arnold SE, Barber R, Barnes LL, Beach TG, Becker JT, Beekly D, Bigio EH, Bowen JD, Boxer A, Burke JR, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carney RM, Carrasquillo MM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cribbs DH, Crocco EA, DeCarli C, DeKosky ST, Dick M, Dickson DW, Duara R, Faber KM, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lin CF, Lopez OL, Lyketsos CG, Mack WJ, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Murrell JR, Olichney JM, Pankratz VS, Parisi JE, Paulson HL, Peskind E, Petersen RC, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reisberg B, Ringman JM, Roberson ED, Rosen HJ, Rosenberg RN, Sano M, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Valladares O, Van Deerlin VM, Van Eldik LJ, Vardarajan BN, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Wishnek S, Woltjer RL, Wright CB, Younkin SG, Yu CE, Yu L, Alzheimer Disease Genetics Consortium. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. JAMA Neurol. 2014 Nov; 71 (11):1394-404
    View PubMed
  78. Batista D, Raffals L. Role of intestinal bacteria in the pathogenesis of pouchitis. Inflamm Bowel Dis. 2014 Aug; 20 (8):1481-6
    View PubMed
  79. Huse1 SM, Young VB, Morrison HG, Antonopoulos DA, Kwon J, Dalal S, Arrieta R, Hubert NA, Shen L, Vineis JH, Koval JC, Sogin ML, Chang EB, Raffals LE. Comparison of brush and biopsy sampling methods of the ileal pouch for assessment of mucosa-associated microbiota of human subjects. Microbiome. Feb 2014; 2(5).
  80. Kane SV, Neis B, Becker BD, Bruining D, Faubion WA, Kisiel J, Loftus EV Jr, Pardi D, Raffals L, Schroeder K, Tremaine WJ. Letter: Effectiveness of split-dose certolizumab pegol for Crohn's disease. Aliment Pharmacol Ther 2013 Dec; 38 (11-12):1412
    View PubMed
  81. McCurdy JD, Loftus EV Jr, Tremaine WJ, Smyrk TC, Bruining DH, Pardi DS, Raffals LE, Kisiel JB, Coelho-Prabhu N, Kane SV, Faubion WA, Papadakis KA. Cytomegalovirus infection of the ileoanal pouch: clinical characteristics and outcomes. Inflamm Bowel Dis. 2013 Oct; 19 (11):2394-9
    View PubMed
  82. Hoentjen F, Seinen ML, Hanauer SB, de Boer NK, Rubin DT, Bouma G, Harrell LE, van Bodegraven AA. Safety and effectiveness of long-term allopurinol-thiopurine maintenance treatment in inflammatory bowel disease. Inflamm Bowel Dis. 2013 Feb; 19(2):363-9.
    View PubMed
  83. Raffals L, Camilleri M. Visceral hypersensitivity and IBD. Inflammatory Bowel Disease Monitor. 2013; 13(3):85-91.
  84. Vital M, Young VB, Raffals LE, Huse S, Schloss P, Dai D, Brulc JM, Antonopoulos DA, Arrieta R, Kwon J, Reddy G, Hubert N, Dalal S, Morrison H, Eren MA, Schmidt TM, Sogin M, Chang EB, Tiedje J. A gene-targeted approach to investigate the intestinal butyrate-producing bacterial community. Microbiom. 2013; 1(8).
  85. Young VB, Raffals LH, Huse S, Schloss PD, Vital M, Dai D, Brulc JM, Antonopoulos DA, Arrieta R, Kwon J, Reddy G, Hubert N, Dalal S, Morrison H, Eren MA, Schmidt TM, Tiedje J, Sogin M, Chang EB, Mitchell SL. Multiphasic Analysis of the Temporal Development of the Distal Gut Microbiota in Patients Following Ileal Pouch-Anal Anastomosis. Microbiome. 2013; 1(9).
  86. Cheifetz AS, Melmed GY, Spiegel B, Talley J, Devlin SM, Raffals L, Irving PM, Jones J, Kaplan GG, Kozuch P, Sparrow M, Velayos F, Baidoo L, Bressler B, Siegel CA. Setting priorities for comparative effectiveness research in inflammatory bowel disease: results of an international provider survey, expert RAND panel, and patient focus groups. Inflamm Bowel Dis. 2012 Dec; 18(12):2294-300. Epub 2012 Feb 15.
    View PubMed
  87. Cohen RD, Lewis JR, Turner H, Harrell LE, Hanauer SB, Rubin DT. Predictors of adalimumab dose escalation in patients with Crohn's disease at a tertiary referral center. Inflamm Bowel Dis. 2012 Jan; 18(1):10-6. Epub 2011 Mar 31.
    View PubMed
  88. Harrell LE, Wang Y, Antonopoulos D, Young V, Lichtenstein GL, Huang Y, Hanauer S, Chang E. Standard colonic lavage alters the natural state of mucosal-associated microbiota in the human colon. PLOS. 2011; 7(2):e32545.
  89. Wang Y, Antonopoulos DA, Zhu X, Harrell L, Hanan I, Alverdy JC, Meyer F, Musch MW, Young VB, Chang EB. Laser capture microdissection and metagenomic analysis of intact mucosa-associated microbial communities of human colon. Appl Microbiol Biotechnol. 2010 Dec; 88(6):1333-42. Epub 2010 Oct 08.
    View PubMed
  90. Melmed GY, Spiegel BM, Bressler B, Cheifetz AS, Devlin SM, Harrell LE, Irving PM, Jones J, Kaplan GG, Kozuch PL, Velayos FS, Baidoo L, Sparrow MP, Siegel CA. The appropriateness of concomitant immunomodulators with anti-tumor necrosis factor agents for Crohn's disease: one size does not fit all. Clin Gastroenterol Hepatol. 2010 Aug; 8(8):655-9. Epub 2010 May 06.
    View PubMed
  91. Beniwal P, Harrell LE. The Status of Diagnostic Markers for Inflammatory Bowel Disease. Curr Gastroenterol Rep. 2010.
  92. Khan O, Harrell LE. Fecal Markers of Disease Recurrence in IBD. IBD Monitor.2010;
  93. Farhadi A, Gundlapalli S, Shaikh M, Frantzides C, Harrell L, Kwasny MM, Keshavarzian A. Susceptibility to gut leakiness: a possible mechanism for endotoxaemia in non-alcoholic steatohepatitis. Liver Int. 2008 Aug; 28(7):1026-33. Epub 2008 Apr 07.
    View PubMed
  94. Sparrow MP, Irving PM, Baidoo, Bressler B, Cheifetz AS, Devlin SM, Harrell LE, Jones J, Kozuch PL, Melmed GY, Velayos FS, Siegel CA. Current controversies in Crohn's disease: A roundtable discussion of the BRIDGe group. Gastroenterology and Hepatology. 2008; 4(10):713-20.
  95. Dassopoulos T, Nguyen GC, Bitton A, Bromfield GP, Schumm LP, Wu Y, Elkadri A, Regueiro M, Siemanowski B, Torres EA, Gregory FJ, Kane SV, Harrell LE, Franchimont D, Achkar JP, Griffiths A, Brant SR, Rioux JD, Taylor KD, Duerr RH, Silverberg MS, Cho JH, Steinhart AH. Assessment of reliability and validity of IBD phenotyping within the National Institutes of Diabetes and Digestive and Kidney Diseases (NIDDK) IBD Genetics Consortium (IBDGC). Inflamm Bowel Dis. 2007 Aug; 13(8):975-83.
    View PubMed
  96. Harrell LE. Evolving Serological Markers for IBD. Inflamm Bowel Dis Monitor. 2007; 8(2):1-8.
  97. Harrell LE. Advances in IBD. Genotype/Phenotype Correlations in Inflammatory Bowel Disease. Gastroenterology and Hepatology. 2007; 3(7):535-37.
  98. Harrell LE, Rubin DT, Hanauer SB. Fever and right upper quadrant pain in a pregnant woman at 30 weeks' gestation. Nat Clin Pract Gastroenterol Hepatol. 2004 Dec; 1(2):113-6; quiz 1 p following 116.
    View PubMed
  99. Harrell LE, Hanauer SB. Mesalamine derivatives in the treatment of inflammatory bowel disease. Gastroenterology Clinics in North America. 2004; 33(2):303-18.
  100. Angtuaco TL, Reddy SK, Drapkin S, Harrell LE, Howden CW. The utility of urgent colonoscopy in the evaluation of acute lower gastrointestinal tract bleeding: a 2-year experience from a single center. Am J Gastroenterol. 2001 Jun; 96(6):1782-5.
    View PubMed