Publications

1. Desai A, Smith CJ, Ashara Y, Orme JJ, Zanwar S, Potter A, Hocum C, Moffett JN, Schwecke AJ, Manochakian R, Lou Y, Zhao Y, Ernani V, Savvides P, Molina J, Dimou A, Mansfield AS, Parikh K, Leventakos K. Real-World Outcomes With Lurbinectedin in Second-Line Setting and Beyond for Extensive Stage Small Cell Lung Cancer. Clin Lung Cancer. 2023 Dec; 24 (8):689-695.e1 Epub 2023 Sept 17
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2. Gicobi JK, Mao Z, DeFranco G, Hirdler JB, Li Y, Vianzon VV, Dellacecca ER, Hsu MA, Barham W, Yan Y, Mansfield AS, Lin Y, Wu X, Hitosugi T, Owen D, Grams MP, Orme JJ, Lucien F, Zeng H, Park SS, Dong H. Salvage therapy expands highly cytotoxic and metabolically fit resilient CD8(+) T cells via ME1 up-regulation. Sci Adv. 2023 Nov 17; 9 (46):eadi2414 Epub 2023 Nov 15
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3. Mahmoud AM, Childs DS, Ahmed ME, Tuba Kendi A, Johnson GB, Orme JJ, Stish BJ, Phillips RM, Park SS, Davis BJ, Andrews JR, Kwon ED. Treatment modalities and survival outcomes in prostate cancer parenchymal brain metastasis. Prostate. 2023 Oct 29 [Epub ahead of print]
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4. Kochan DC, Novotny PJ, Cathcart-Rake EJ, Orme JJ, Tevaarwerk AJ, Ruddy KJ, Childs DS. An evaluation of the effect of lithium on taxane-induced neuropathy. Support Care Cancer. 2023 Apr 25; 31 (5):299
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5. Mahmoud AM, Nabavizadeh R, Rodrigues Pessoa R, Garg I, Orme J, Costello BA, Cheville J, Lucien F. Antibody-Based Therapeutics for the Treatment of Renal Cell Carcinoma: Challenges and Opportunities. Oncologist. 2023 Apr 6; 28 (4):297-308
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6. Huang Z, Li X, Tang B, Li H, Zhang J, Sun R, Ma J, Pan Y, Yan B, Zhou Y, Ding D, Yan Y, Jimenez R, Orme JJ, Jin X, Yang J, Huang H, Jia Z. SETDB1 Modulates Degradation of Phosphorylated RB and Anticancer Efficacy of CDK4/6 Inhibitors. Cancer Res. 2023 Mar 15; 83 (6):875-889
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7. Orme JJ, Mer G, Huang H. Hidden tricks in MATH: Hypermorphic mutations in SPOP tumor suppressor explained by cryo-EM. Mol Cell 2023 Mar 2; 83 (5):655-656
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8. Childs DS, Helfinstine DA Jr, Sangaralingham L, Orme JJ, O'Sullivan CC, Loprinzi CL, Ruddy KJ. Slow Uptake of an Effective Therapy: Patterns of Olanzapine Prescribing for Those Receiving Highly Emetogenic Chemotherapy. JCO Oncol Pract. 2022 Dec; 18 (12):e1953-e1960 Epub 2022 Oct 31
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9. Lucien F, Kim Y, Qian J, Orme JJ, Zhang H, Arafa A, Abraha F, Thapa I, Tryggestad EJ, Harmsen WS, Kosti J, Ali H, Lowe VJ, Johnson GB, Kwon ED, Dong H, Park SS. Tumor-Derived Extracellular Vesicles Predict Clinical Outcomes in Oligometastatic Prostate Cancer and Suppress Antitumor Immunity. Int J Radiat Oncol Biol Phys. 2022 Nov 15; 114 (4):725-737 Epub 2022 June 04
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10. Chinniah S, Stish B, Costello BA, Pagliaro L, Childs D, Quevedo F, Lucien F, Bryce A, Park SS, Orme JJ. Radiation Therapy in Oligometastatic Prostate Cancer. Int J Radiat Oncol Biol Phys. 2022 Nov 15; 114 (4):684-692 Epub 2022 July 22
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11. Desai AP, Scheckel CJ, Soderberg LC, Jensen CJ, Orme JJ, Tella SH, Kommalapati A, Pritchett JC, Khera N, Mahipal A, Go RS, Mayo Clinic Hematology and ONcology Outcomes Research (HONOR) Group. Economic Cost and Sustainability of Oral Therapies in Precision Oncology. JCO Oncol Pract. 2022 Aug; 18 (8):e1247-e1254 Epub 2022 May 26
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12. Mahmoud AM, Frank I, Orme JJ, Lavoie RR, Thapa P, Costello BA, Cheville JC, Gupta S, Dong H, Lucien F. Evaluation of PD-L1 and B7-H3 expression as a predictor of response to adjuvant chemotherapy in bladder cancer. BMC Urol. 2022 Jun 24; 22 (1):90 Epub 2022 June 24
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13. Davidson TM, Foster N, Lucien F, Markovic S, Dong H, Winters JL, Park SS, Orme JJ. Rescuing Cancer Immunity by Plasma Exchange in Metastatic Melanoma (ReCIPE-M1): protocol for a single-institution, open-label safety trial of plasma exchange to clear sPD-L1 for immunotherapy. BMJ Open. 2022 May 12; 12 (5):e050112
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14. Lindner AK, Furlan T, Orme JJ, Tulchiner G, Staudacher N, D'Andrea D, Culig Z, Pichler R. HUS1 as a Potential Therapeutic Target in Urothelial Cancer. J Clin Med. 2022 Apr 15; 11 (8)
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15. Orme JJ, Pagliaro LC, Quevedo JF, Park SS, Costello BA. Rational Second-Generation Antiandrogen Use in Prostate Cancer. Oncologist. 2022 Mar 4; 27 (2):110-124
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16. Desai A, Scheckel C, Jensen CJ, Orme J, Williams C, Shah N, Leventakos K, Adjei AA. Trends in Prices of Drugs Used to Treat Metastatic Non-Small Cell Lung Cancer in the US From 2015 to 2020. JAMA Netw Open. 2022 Jan 4; 5 (1):e2144923 Epub 2022 Jan 04
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17. Chinniah S, Stish B, Costello BA, Pagliaro L, Childs D, Quevedo F, Lucien F, Bryce A, Park SS, Orme JJ. Radiation therapy in oligometastatic prostate cancer. International Journal of Radiation Oncology, Biology, Physics. 2022; 114 (4):684-92
    
18. Zhang H, Orme JJ, Abraha F, Stish BJ, Lowe VJ, Lucien F, Tryggestad EJ, Bold MS, Pagliaro LC, Choo CR, Brinkmann DH, Iott MJ, Davis BJ, Quevedo JF, Harmsen WS, Costello BA, Johnson GB, Nathan MA, Olivier KR, Pisansky TM, Kwon ED, Dong H, Park SS. Phase II Evaluation of Stereotactic Ablative Radiotherapy (SABR) and Immunity in (11)C-Choline-PET/CT-Identified Oligometastatic Castration-Resistant Prostate Cancer. Clin Cancer Res. 2021 Dec 1; 27 (23):6376-6383 Epub 2021 Sept 30
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19. Wee CE, Costello BA, Orme JJ, Quevedo JF, Pagliaro LC. Chemotherapy with atezolizumab for small cell or neuroendocrine carcinoma of the prostate: A single institution experience. Prostate. 2021 Sep; 81 (13):938-943 Epub 2021 July 12
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20. Shi L, Yan Y, He Y, Yan B, Pan Y, Orme JJ, Zhang J, Xu W, Pang J, Huang H. Mutated SPOP E3 Ligase Promotes 17betaHSD4 Protein Degradation to Drive Androgenesis and Prostate Cancer Progression. Cancer Res. 2021 Jul 1; 81 (13):3593-3606 Epub 2021 Mar 24
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21. Tulchiner G, Brunner A, Schmidinger M, Staudacher N, Orme JJ, Thurnher M, Horninger W, Culig Z, Pichler R. CMTM6 expression as a potential biomarker for immunotherapy in metastatic renal cell carcinoma. BJU Int. 2021 Jul; 128 (1):29-32 Epub 2021 Feb 07
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22. He Y, Wei T, Ye Z, Orme JJ, Lin D, Sheng H, Fazli L, Jeffrey Karnes R, Jimenez R, Wang L, Wang L, Gleave ME, Wang Y, Shi L, Huang H. A noncanonical AR addiction drives enzalutamide resistance in prostate cancer. Nat Commun. 2021 Mar 9; 12 (1):1521 Epub 2021 Mar 09
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23. Wu D, Yan Y, Wei T, Ye Z, Xiao Y, Pan Y, Orme JJ, Wang D, Wang L, Ren S, Huang H. An acetyl-histone vulnerability in PI3K/AKT inhibition-resistant cancers is targetable by both BET and HDAC inhibitors. Cell Rep. 2021 Feb 16; 34 (7):108744
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24. Pichler R, Lindner AK, Schafer G, Tulchiner G, Staudacher N, Mayr M, Comperat E, Orme JJ, Schachtner G, Thurnher M. Expression of ADAM Proteases in Bladder Cancer Patients with BCG Failure: A Pilot Study. J Clin Med. 2021 Feb 14; 10 (4)
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25. Orme JJ, Huang H. Microenvironment-Mediated Resistance to Anti-Androgen Therapy. Cancer Cell 2020 Aug 10; 38 (2):155-157
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26. Orme JJ, Enninga EAL, Lucien-Matteoni F, Dale H, Burgstaler E, Harrington SM, Ball MK, Mansfield AS, Park SS, Block MS, Markovic SN, Yan Y, Dong H, Dronca RS, Winters JL. Therapeutic plasma exchange clears circulating soluble PD-L1 and PD-L1-positive extracellular vesicles. J Immunother Cancer. 2020 Aug; 8 (2)
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27. Orme JJ, Jazieh KA, Xie T, Harrington S, Liu X, Ball M, Madden B, Charlesworth MC, Azam TU, Lucien F, Wootla B, Li Y, Villasboas JC, Mansfield AS, Dronca RS, Dong H. ADAM10 and ADAM17 cleave PD-L1 to mediate PD-(L)1 inhibitor resistance. Oncoimmunology. 2020; 9(1):1744980. Epub 2020 Apr 14.
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28. Orme JJ, Sidana S, Gonsalves WI. 59-Year-Old Man With Fatigue, Weight Loss, and Hepatomegaly. Mayo Clin Proc. 2018 Oct; 93 (10):1525-1529 Epub 2018 Aug 10
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29. Orme J, Purushotham D. Axillary Mass and Hypercalcemia: The Value of a Physical Examination. Am J Med. 2017 Dec; 130 (12):e541-e542 Epub 2017 July 17
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