Publications

  1. Gong H, Tao S, Rajendran K, Zhou W, McCollough CH, Leng S. Deep-learning-based direct inversion for material decomposition. Med Phys. 2020 Oct 6 Epub 2020 Oct 06
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  2. Lee O, Rajendran K, Polster C, Stierstorfer K, Kappler S, Leng S, McCollough CH, Taguchi K. X-ray Transmittance Modeling-based Material Decomposition using a Photon-counting Detector CT System IEEE Transactions on Radiation and Plasma Medical Sciences. 2020.
  3. Fletcher JG, Levin DL, Sykes AG, Lindell RM, White DB, Kuzo RS, Suresh V, Yu L, Leng S, Holmes DR 3rd, Inoue A, Johnson MP, Carter RE, McCollough CH. Observer Performance for Detection of Pulmonary Nodules at Chest CT over a Large Range of Radiation Dose Levels. Radiology. 2020 Sep 29; 200969 Epub 2020 Sept 29
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  4. Rajiah P, Parakh A, Kay F, Baruah D, Kambadakone AR, Leng S. Update on Multienergy CT: Physics, Principles, and Applications. Radiographics. 2020 Sep-Oct; 40 (5):1284-1308 Epub 2020 Aug 21
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  5. McCollough CH, Leng S. Use of artificial intelligence in computed tomography dose optimisation. Ann ICRP. 2020 Sep 1; 146645320940827 Epub 2020 Sept 01
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  6. Li Z, Leng S, Halaweish AF, Yu Z, Yu L, Ritman EL, McCollough CH. Overcoming calcium blooming and improving the quantification accuracy of percent area luminal stenosis by material decomposition of multi-energy computed tomography datasets. J Med Imaging (Bellingham). 2020 Sep; 7 (5):053501 Epub 2020 Oct 01
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  7. Tao S, Marsh JF, Tao A, Michalak GJ, Rajendran K, McCollough CH, Leng S. Multi-energy CT imaging for large patients using dual-source photon-counting detector CT. Phys Med Biol. 2020 Aug 31; 65 (17):17NT01
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  8. Hsieh S, Leng S, Tao S, Rajendran K, McCollough CH. Photon Counting CT: Clinical Applications and Future Developments IEEE Transactions on Radiation and Plasma Medical Sciences. 2020.
  9. Jacobsen MC, Thrower SL, Ger RB, Leng S, Court LE, Brock KK, Tamm EP, Cressman ENK, Cody DD, Layman RR. Multi-energy computed tomography and material quantification: Current barriers and opportunities for advancement. Med Phys. 2020 Aug; 47 (8):3752-3771 Epub 2020 June 23
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  10. Gong H, Hu Q, Walther A, Koo CW, Takahashi EA, Levin DL, Johnson TF, Hora MJ, Leng S, Fletcher JG, McCollough CH, Yu L. Deep-learning-based model observer for a lung nodule detection task in computed tomography. J Med Imaging (Bellingham). 2020 Jul; 7 (4):042807 Epub 2020 June 30
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  11. Rajendran K, Murthy NS, Frick MA, Tao S, Unger MD, LaVallee KT, Larson NB, Leng S, Maus TP, McCollough CH. Quantitative Knee Arthrography in a Large Animal Model of Osteoarthritis Using Photon-Counting Detector CT. Invest Radiol. 2020 Jun; 55 (6):349-356
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  12. D'Souza RS, Li L, Leng S, Hunt C, Law L, Muir C, Eldrige J, Bydon M, Chi M, Shapiro S, Mauck WD, Qu W. A three-dimensional computed tomography study to determine the ideal method for fluoroscopically-guided bone marrow aspiration from the iliac crest. Bosn J Basic Med Sci. 2020 May 11 [Epub ahead of print]
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  13. Zhou W, Michalak GJ, Weaver JM, Gong H, Yu L, McCollough CH, Leng S. A Universal Protocol for Abdominal CT Examinations Performed on a Photon-Counting Detector CT System: A Feasibility Study. Invest Radiol. 2020 Apr; 55 (4):226-232
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  14. Lester SC, Taparra K, Petersen MM, Funk RK, Blanchard MJ, Young PM, Herrmann J, Hunzeker AE, Schultz HL, McCollough C, Tasson AM, Leng S, Martenson JA, Deisher AJ, Whitaker TJ, Williamson EE, Laack NN. Electrocardiogram-Gated Computed Tomography with Coronary Angiography for Cardiac Substructure Delineation and Sparing in Patients with Mediastinal Lymphomas Treated with Radiation Therapy. Pract Radiat Oncol. 2020 Mar - Apr; 10 (2):104-111 Epub 2019 Nov 26
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  15. Rizvi A, Marcus RP, Guo Y, Carter R, Mark IT, Foley TA, Weber NM, Sheedy EN, Leng S, Williamson EE. Dynamic computed tomographic assessment of the mitral annulus in patients with and without mitral prolapse. J Cardiovasc Comput Tomogr. 2020 Feb 27 [Epub ahead of print]
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  16. Missert AD, Yu L, Leng S, Fletcher JG, McCollough CH. Synthesizing images from multiple kernels using a deep convolutional neural network. Med Phys. 2020 Feb; 47 (2):422-430 Epub 2019 Dec 29
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  17. Rajendran K, Voss BA, Zhou W, Tao S, DeLone DR, Lane JI, Weaver JM, Carlson ML, Fletcher JG, McCollough CH, Leng S. Dose Reduction for Sinus and Temporal Bone Imaging Using Photon-Counting Detector CT With an Additional Tin Filter. Invest Radiol. 2020 Feb; 55 (2):91-100
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  18. Baffour FI, Glazebrook KN, Morris JM, Michalak GJ, Fletcher JG, Leng S, McCollough CH. Clinical utility of virtual noncalcium dual-energy CT in imaging of the pelvis and hip. Skeletal Radiol. 2019 Dec; 48 (12):1833-1842 Epub 2019 May 30
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  19. Samei E, Bakalyar D, Boedeker KL, Brady S, Fan J, Leng S, Myers KJ, Popescu LM, Ramirez Giraldo JC, Ranallo F, Solomon J, Vaishnav J, Wang J. Performance evaluation of computed tomography systems: Summary of AAPM Task Group 233. Med Phys. 2019 Nov; 46 (11):e735-e756 Epub 2019 Sept 11
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  20. Fletcher JG, DeLone DR, Kotsenas AL, Campeau NG, Lehman VT, Yu L, Leng S, Holmes DR 3rd, Edwards PK, Johnson MP, Michalak GJ, Carter RE, McCollough CH. Evaluation of Lower-Dose Spiral Head CT for Detection of Intracranial Findings Causing Neurologic Deficits. AJNR Am J Neuroradiol. 2019 Nov; 40 (11):1855-1863 Epub 2019 Oct 24
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  21. Navin PJ, Kim B, Wells ML, Khandelwal A, Halaweish AF, Moen TR, Johnson MP, McCollough S, Lee YS, Leng S, McCollough CH, Fletcher JG. Reducing radiation dose for multi-phase contrast-enhanced dual energy renal CT: pilot study evaluating prior iterative reconstruction. Abdom Radiol (NY). 2019 Oct; 44 (10):3350-3358
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  22. Zhou W, Michalak G, Weaver J, Ferrero A, Gong H, Fetterly KA, McCollough CH, Leng S. Determination of iodine detectability in different types of multiple-energy images for a photon-counting detector computed tomography system. J Med Imaging (Bellingham). 2019 Oct; 6 (4):043501 Epub 2019 Oct 15
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  23. Sheikhzadeh M, Vercnocke AJ, Tao S, Rajendran K, Leng S, Ritman EL, McCollough CH. Impact of Effective Detector Pixel and CT Voxel Size on Accurate Estimation of Blood Volume in Opacified Microvasculature. Acad Radiol. 2019 Oct; 26 (10):1410-1416 Epub 2018 Dec 07
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  24. Morris J, Michalak G, Leng S, Moynagh M, Kurup AN, McCollough C, Fletcher J. Dual-Energy CT Monitoring of Cryoablation Zone Growth in the Spinal Column and Bony Pelvis: A Laboratory Study. J Vasc Interv Radiol. 2019 Sep; 30 (9):1496-1503 Epub 2019 May 18
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  25. Tao S, Rajendran K, McCollough CH, Leng S. Feasibility of multi-contrast imaging on dual-source photon counting detector (PCD) CT: An initial phantom study. Med Phys. 2019 Sep; 46 (9):4105-4115 Epub 2019 July 05
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  26. Tao A, Huang R, Tao S, Michalak GJ, McCollough CH, Leng S. Dual-source photon counting detector CT with a tin filter: a phantom study on iodine quantification performance. Phys Med Biol. 2019 May 31; 64 (11):115019
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  27. Tao S, Rajendran K, Zhou W, Fletcher JG, McCollough CH, Leng S. Improving iodine contrast to noise ratio using virtual monoenergetic imaging and prior-knowledge-aware iterative denoising (mono-PKAID). Phys Med Biol. 2019 May 16; 64 (10):105014
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  28. Dilger SKN, Yu L, Chen B, Favazza CP, Carter RE, Fletcher JG, McCollough CH, Leng S. Localization of liver lesions in abdominal CT imaging: I. Correlation of human observer performance between anatomical and uniform backgrounds. Phys Med Biol. 2019 May 10; 64 (10):105011
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  29. Dilger SKN, Leng S, Chen B, Carter RE, Favazza CP, Fletcher JG, McCollough CH, Yu L. Localization of liver lesions in abdominal CT imaging: II. Mathematical model observer performance correlates with human observer performance for localization of liver lesions in abdominal CT imaging. Phys Med Biol. 2019 May 10; 64 (10):105012
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  30. Gong H, Yu L, Leng S, Dilger SK, Ren L, Zhou W, Fletcher JG, McCollough CH. A deep learning- and partial least square regression-based model observer for a low-contrast lesion detection task in CT. Med Phys. 2019 May; 46 (5):2052-2063 Epub 2019 Apr 01
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  31. Leng S, Bruesewitz M, Tao S, Rajendran K, Halaweish AF, Campeau NG, Fletcher JG, McCollough CH. Photon-counting Detector CT: System Design and Clinical Applications of an Emerging Technology. Radiographics. 2019 May-Jun; 39 (3):729-743
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  32. Zhou W, Bartlett DJ, Diehn FE, Glazebrook KN, Kotsenas AL, Carter RE, Fletcher JG, McCollough CH, Leng S. Reduction of Metal Artifacts and Improvement in Dose Efficiency Using Photon-Counting Detector Computed Tomography and Tin Filtration. Invest Radiol. 2019 Apr; 54 (4):204-211
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  33. Glazebrook KN, Doerge S, Leng S, Drees TA, Hunt KN, Zingula SN, Pruthi S, Geske JR, Carter RE, McCollough CH, Fletcher JG. Ability of Dual-Energy CT to Detect Silicone Gel Breast Implant Rupture and Nodal Silicone Spread. AJR Am J Roentgenol. 2019 Apr; 212 (4):933-942 Epub 2019 Feb 19
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  34. Bartlett DJ, Koo CW, Bartholmai BJ, Rajendran K, Weaver JM, Halaweish AF, Leng S, McCollough CH, Fletcher JG. High-Resolution Chest Computed Tomography Imaging of the Lungs: Impact of 1024 Matrix Reconstruction and Photon-Counting Detector Computed Tomography. Invest Radiol. 2019 Mar; 54 (3):129-137
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  35. Shanblatt ER, Sung Y, Gupta R, Nelson BJ, Leng S, Graves WS, McCollough CH. Forward model for propagation-based x-ray phase contrast imaging in parallel- and cone-beam geometry. Opt Express. 2019 Feb 18; 27 (4):4504-4521
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  36. Nelson B, Koenig T, Shanblatt E, Leng S, McCollough C. Visibility guided phase contrast denoising Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2019; 10948:109484V
  37. Gomez-Cardona D, Leng S, Favazza CP, Schueler BA, Fetterly KA. Automatic strategy for CHO channel reduction in x-ray angiography systems Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2019; 10952:1095205
  38. Leng S, Rajendran K, Gong H, Zhou W, Halaweish AF, Henning A, Kappler S, Baer M, Fletcher JG, McCollough CH. 150-mum Spatial Resolution Using Photon-Counting Detector Computed Tomography Technology: Technical Performance and First Patient Images. Invest Radiol. 2018 Nov; 53 (11):655-662
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  39. Marcus RP, Fletcher JG, Ferrero A, Leng S, Halaweish AF, Gutjahr R, Vrtiska TJ, Wells ML, Enders FT, McCollough CH. Detection and Characterization of Renal Stones by Using Photon-Counting-based CT. Radiology. 2018 Nov; 289 (2):436-442 Epub 2018 Aug 07
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  40. Fletcher JG, Fidler JL, Venkatesh SK, Hough DM, Takahashi N, Yu L, Johnson M, Leng S, Holmes DR 3rd, Carter R, McCollough CH. Observer Performance with Varying Radiation Dose and Reconstruction Methods for Detection of Hepatic Metastases. Radiology. 2018 Nov; 289 (2):455-464 Epub 2018 Sept 11
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  41. Leng S. Radiation Dose in CT-guided Interventional Procedures: Establishing a Benchmark. Radiology 2018 Oct; 289 (1):158-159 Epub 2018 July 17
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  42. Ferrero A, Gutjahr R, Halaweish AF, Leng S, McCollough CH. Characterization of Urinary Stone Composition by Use of Whole-body, Photon-counting Detector CT. Acad Radiol. 2018 Oct; 25 (10):1270-1276 Epub 2018 Feb 14
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  43. Marsh JF, Jorgensen SM, Rundle DS, Vercnocke AJ, Leng S, Butler PH, McCollough CH, Ritman EL. Evaluation of a photon counting Medipix3RX cadmium zinc telluride spectral x-ray detector. J Med Imaging (Bellingham). 2018 Oct; 5 (4):043503 Epub 2018 Dec 04
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  44. Tao S, Rajendran K, McCollough CH, Leng S. Material decomposition with prior knowledge aware iterative denoising (MD-PKAID). Phys Med Biol. 2018 Sep 21; 63 (19):195003 Epub 2018 Sept 21
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  45. Samreen N, Glazebrook KN, Bhatt A, Venkatesh SK, McMenomy BP, Chandra A, Leng S, Adler KE, McCollough CH. Imaging findings of mammary and systemic silicone deposition secondary to breast implants. Br J Radiol. 2018 Sep; 91 (1089):20180098 Epub 2018 May 10
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  46. Zhou W, Lane JI, Carlson ML, Bruesewitz MR, Witte RJ, Koeller KK, Eckel LJ, Carter RE, McCollough CH, Leng S. Comparison of a Photon-Counting-Detector CT with an Energy-Integrating-Detector CT for Temporal Bone Imaging: A Cadaveric Study. AJNR Am J Neuroradiol. 2018 Sep; 39 (9):1733-1738 Epub 2018 Aug 09
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  47. Long Z, Bruesewitz MR, DeLone DR, Morris JM, Amrami KK, Adkins MC, Glazebrook KN, Kofler JM, Leng S, McCollough CH, Fletcher JG, Halaweish AF, Yu L. Evaluation of projection- and dual-energy-based methods for metal artifact reduction in CT using a phantom study. J Appl Clin Med Phys. 2018 Jul; 19 (4):252-260 Epub 2018 May 10
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  48. Yu L, Ren L, Li Z, Leng S, McCollough CH. Dual-source multienergy CT with triple or quadruple x-ray beams. J Med Imaging (Bellingham). 2018 Jul; 5 (3):033502 Epub 2018 July 24
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  49. Hanson GJ, Michalak GJ, Childs R, McCollough B, Kurup AN, Hough DM, Frye JM, Fidler JL, Venkatesh SK, Leng S, Yu L, Halaweish AF, Harmsen WS, McCollough CH, Fletcher JG. Low kV versus dual-energy virtual monoenergetic CT imaging for proven liver lesions: what are the advantages and trade-offs in conspicuity and image quality? A pilot study. Abdom Radiol (NY). 2018 Jun; 43 (6):1404-1412
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  50. Rajendran K, Tao S, Abdurakhimova D, Leng S, McCollough C. Ultra-High Resolution Photon-Counting Detector CT Reconstruction using Spectral Prior Image Constrained Compressed-Sensing (UHR-SPICCS). Proc SPIE Int Soc Opt Eng. 2018 Mar; 10573
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  51. Rajendran K, Leng S, Jorgensen SM, Anderson JL, Halaweish AF, Abdurakhimova D, Ritman EL, McCollough CH. Measuring arterial wall perfusion using photon-counting computed tomography (CT): improving CT number accuracy of artery wall using image deconvolution. J Med Imaging (Bellingham). 2017 Oct; 4 (4):044006 Epub 2017 Dec 08
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  52. Sung Y, Gupta R, Nelson B, Leng S, McCollough CH, Graves WS. Phase-contrast imaging with a compact x-ray light source: system design. J Med Imaging (Bellingham). 2017 Oct; 4 (4):043503 Epub 2017 Nov 23
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  53. McCollough CH, Bartley AC, Carter RE, Chen B, Drees TA, Edwards P, Holmes DR 3rd, Huang AE, Khan F, Leng S, McMillan KL, Michalak GJ, Nunez KM, Yu L, Fletcher JG. Low-dose CT for the detection and classification of metastatic liver lesions: Results of the 2016 Low Dose CT Grand Challenge. Med Phys. 2017 Oct; 44 (10):e339-e352
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  54. Zhou W, Montoya J, Gutjahr R, Ferrero A, Halaweish A, Kappler S, McCollough C, Leng S. Lung nodule volume quantification and shape differentiation with an ultra-high resolution technique on a photon-counting detector computed tomography system. J Med Imaging (Bellingham). 2017 Oct; 4 (4):043502 Epub 2017 Nov 16
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  55. Michalak G, Grimes J, Fletcher J, Halaweish A, Yu L, Leng S, McCollough C. Selection of optimal tube potential settings for dual-energy CT virtual mono-energetic imaging of iodine in the abdomen. Abdom Radiol (NY). 2017 Sep; 42 (9):2289-2296
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  56. Leng S, Zhou W, Yu Z, Halaweish A, Krauss B, Schmidt B, Yu L, Kappler S, McCollough C. Spectral performance of a whole-body research photon counting detector CT: quantitative accuracy in derived image sets. Phys Med Biol. 2017 Aug 21; 62 (17):7216-7232
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  57. Wells ML, Froemming AT, Kawashima A, Vrtiska TJ, Kim B, Hartman RP, Holmes DR 3rd, Carter RE, Bartley AC, Leng S, McCollough CH, Fletcher JG. A multi-reader in vitro study using porcine kidneys to determine the impact of integrated circuit detectors and iterative reconstruction on the detection accuracy, size measurement, and radiation dose for small (<4 mm) renal stones. Acta Radiol. 2017 Aug; 58: (8)1012-1019.
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  58. Yu L, Chen B, Kofler JM, Favazza CP, Leng S, Kupinski MA, McCollough CH. Correlation between a 2D channelized Hotelling observer and human observers in a low-contrast detection task with multislice reading in CT. Med Phys. 2017 Aug; 44 (8):3990-3999 Epub 2017 July 13
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  59. Carlson ML, Leng S, Diehn FE, Witte RJ, Krecke KN, Grimes J, Koeller KK, Bruesewitz MR, McCollough CH, Lane JI. Cochlear Implant Electrode Localization Using an Ultra-High Resolution Scan Mode on Conventional 64-Slice and New Generation 192-Slice Multi-Detector Computed Tomography. Otol Neurotol. 2017 Aug; 38 (7):978-984
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  60. McMillan K, Bostani M, Cagnon CH, Yu L, Leng S, McCollough CH, McNitt-Gray MF. Estimating patient dose from CT exams that use automatic exposure control: Development and validation of methods to accurately estimate tube current values. Med Phys. 2017 Aug; 44 (8):4262-4275 Epub 2017 June 30
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  61. Huang AE, Montoya JC, Shiung M, Leng S, McCollough CH. Consistency of Renal Stone Volume Measurements Across CT Scanner Model and Reconstruction Algorithm Configurations. AJR Am J Roentgenol. 2017 Jul; 209 (1):116-121 Epub 2017 Apr 12
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  62. Fletcher JG, Yu L, Fidler JL, Levin DL, DeLone DR, Hough DM, Takahashi N, Venkatesh SK, Sykes AG, White D, Lindell RM, Kotsenas AL, Campeau NG, Lehman VT, Bartley AC, Leng S, Holmes DR 3rd, Toledano AY, Carter RE, McCollough CH. Estimation of Observer Performance for Reduced Radiation Dose Levels in CT: Eliminating Reduced Dose Levels That Are Too Low Is the First Step. Acad Radiol. 2017 Jul; 24 (7):876-890 Epub 2017 Mar 02
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  63. Favazza CP, Ferrero A, Yu L, Leng S, McMillan KL, McCollough CH. Use of a channelized Hotelling observer to assess CT image quality and optimize dose reduction for iteratively reconstructed images. J Med Imaging (Bellingham). 2017 Jul; 4 (3):031213 Epub 2017 Oct 03
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  64. Brinjikji W, Michalak G, Kadirvel R, Dai D, Gilvarry M, Duffy S, Kallmes DF, McCollough C, Leng S. Utility of single-energy and dual-energy computed tomography in clot characterization: An in-vitro study. Interv Neuroradiol. 2017 Jun; 23 (3):279-284 Epub 2017 Jan 01
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  65. Leng S, Takahashi N, Gomez Cardona D, Kitajima K, McCollough B, Li Z, Kawashima A, Leibovich BC, McCollough CH. Subjective and objective heterogeneity scores for differentiating small renal masses using contrast-enhanced CT. Abdom Radiol (NY). 2017 May; 42 (5):1485-1492
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  66. Li Z, Leng S, Yu L, Manduca A, McCollough CH. An effective noise reduction method for multi-energy CT images that exploit spatio-spectral features. Med Phys. 2017 May; 44 (5):1610-1623 Epub 2017 Apr 12
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  67. Li Z, Leng S, Yu Z, Kappler S, McCollough CH. Estimation of signal and noise for a whole-body research photon-counting CT system. J Med Imaging (Bellingham). 2017 Apr; 4 (2):023505 Epub 2017 June 22
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  68. Doerge S, Glazebrook ,, Leng S, McCollough C. Utility of Dual-Energy Computed Tomography for Evaluation of Silicone within Internal Mammary Nodes Austin J Clin Case Rep.2017;4:(1):1112.
  69. Ma C, Yu L, Chen B, Koo CW, Takahashi EA, Fletcher JG, Levin DL, Kuzo RS, Viers LD, Vincent-Sheldon SA, Leng S, McCollough CH. Evaluation of a projection-domain lung nodule insertion technique in thoracic computed tomography. J Med Imaging (Bellingham). 2017 Jan; 4 (1):013510 Epub 2017 Mar 31
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  70. Marcus RP, Morris JM, Matsumoto JM, Alexander AE, Halaweish AF, Kelly JA, Fletcher JG, McCollough CH, Leng S. Implementation of iterative metal artifact reduction in the pre-planning-procedure of three-dimensional physical modeling. 3D Print Med. 2017; 3 (1):5 Epub 2017 Mar 31
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  71. Leng S, McGee K, Morris J, Alexander A, Kuhlmann J, Vrieze T, McCollough CH, Matsumoto J. Anatomic modeling using 3D printing: quality assurance and optimization. 3D Print Med. 2017; 3 (1):6 Epub 2017 Apr 26
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  72. Long Z, Bruesewitz MR, Sheedy EN, Powell MA, Kramer JC, Supalla RR, Colvin CM, Bechel JR, Favazza CP, Kofler JM, Leng S, McCollough CH, Yu L. Technical Note: Display window setting: An important factor for detecting subtle but clinically relevant artifacts in daily CT quality control. Med Phys. 2016 Dec; 43: (12)6413.
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  73. Kakar S, Breighner RE, Leng S, McCollough CH, Moran SL, Berger RA, Zhao KD. The Role of Dynamic (4D) CT in the Detection of Scapholunate Ligament Injury. J Wrist Surg. 2016 Nov; 5 (4):306-310 Epub 2016 Jan 18
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  74. Yu Z, Leng S, Kappler S, Hahn K, Li Z, Halaweish AF, Henning A, McCollough CH. Noise performance of low-dose CT: comparison between an energy integrating detector and a photon counting detector using a whole-body research photon counting CT scanner. J Med Imaging (Bellingham). 2016 Oct; 3 (4):043503 Epub 2016 Dec 14
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  75. Leng S, Yu Z, Halaweish A, Kappler S, Hahn K, Henning A, Li Z, Lane J, Levin DL, Jorgensen S, Ritman E, McCollough C. Dose-efficient ultrahigh-resolution scan mode using a photon counting detector computed tomography system. J Med Imaging (Bellingham). 2016 Oct; 3 (4):043504 Epub 2016 Dec 22
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  76. Chen B, Ma C, Leng S, Fidler JL, Sheedy SP, McCollough CH, Fletcher JG, Yu L. Validation of a Projection-domain Insertion of Liver Lesions into CT Images. Acad Radiol. 2016 Oct; 23 (10):1221-9 Epub 2016 July 16
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  77. Yu Z, Leng S, Li Z, McCollough CH. Spectral prior image constrained compressed sensing (spectral PICCS) for photon-counting computed tomography. Phys Med Biol. 2016 Sep 21; 61 (18):6707-6732 Epub 2016 Aug 23
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  78. Grimes J, Leng S, Zhang Y, Vrieze T, McCollough C. Implementation and evaluation of a protocol management system for automated review of CT protocols. J Appl Clin Med Phys. 2016 Sep 8; 17 (5):523-533 Epub 2016 Sept 08
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  79. Leng S, Huang A, Cardona JM, Duan X, Williams JC, McCollough CH. Dual-Energy CT for Quantification of Urinary Stone Composition in Mixed Stones: A Phantom Study. AJR Am J Roentgenol. 2016 Aug; 207 (2):321-9 Epub 2016 May 25
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  80. Gutjahr R, Halaweish AF, Yu Z, Leng S, Yu L, Li Z, Jorgensen SM, Ritman EL, Kappler S, McCollough CH. Human Imaging With Photon Counting-Based Computed Tomography at Clinical Dose Levels: Contrast-to-Noise Ratio and Cadaver Studies. Invest Radiol. 2016 Jul; 51 (7):421-9
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  81. Yu Z, Leng S, Li Z, Halaweish AF, Kappler S, Ritman EL, McCollough CH. How Low Can We Go in Radiation Dose for the Data-Completion Scan on a Research Whole-Body Photon-Counting Computed Tomography System. J Comput Assist Tomogr. 2016 Jul-Aug; 40 (4):663-70
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  82. Leng S, Chen B, Vrieze T, Kuhlmann J, Yu L, Alexander A, Matsumoto J, Morris J, McCollough CH. Construction of realistic phantoms from patient images and a commercial three-dimensional printer. J Med Imaging (Bellingham). 2016 Jul; 3 (3):033501 Epub 2016 July 07
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  83. Takahashi N, Takeuchi M, Sasaguri K, Leng S, Froemming A, Kawashima A. CT negative attenuation pixel distribution and texture analysis for detection of fat in small angiomyolipoma on unenhanced CT. Abdom Radiol (NY). 2016 Jun; 41 (6):1142-51
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  84. Ma C, Yu L, Chen B, Favazza C, Leng S, McCollough C. Impact of number of repeated scans on model observer performance for a low-contrast detection task in computed tomography. J Med Imaging (Bellingham). 2016 Apr; 3 (2):023504 Epub 2016 May 26
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  85. Fletcher JG, Leng S, Yu L, McCollough CH. Dealing with Uncertainty in CT Images. Radiology 2016 Apr; 279 (1):5-10
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  86. Yu Z, Leng S, Jorgensen SM, Li Z, Gutjahr R, Chen B, Halaweish AF, Kappler S, Yu L, Ritman EL, McCollough CH. Evaluation of conventional imaging performance in a research whole-body CT system with a photon-counting detector array. Phys Med Biol. 2016 Feb 21; 61 (4):1572-95 Epub 2016 Feb 02
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  87. McEachen JC, Leng S, Atwell TD, Tollefson MK, Friese JL, Wang Z, Murad MH, Schmit GD. Percutaneous Renal Tumor Ablation: Radiation Exposure During Cryoablation and Radiofrequency Ablation. Cardiovasc Intervent Radiol. 2016 Feb; 39: (2)233-8.
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  88. Li Z, Yu L, Leng S, Williamson EE, Kotsenas AL, DeLone DR, Manduca A, McCollough CH. A robust noise reduction technique for time resolved CT. Med Phys. 2016 Jan; 43: (1)347.
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  89. Michalak G, Grimes J, Fletcher J, Halaweish A, Yu L, Leng S, McCollough C. Technical Note: Improved CT number stability across patient size using dual-energy CT virtual monoenergetic imaging. Med Phys. 2016 Jan; 43: (1)513.
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  90. Glazebrook KN, Leng S, Jacobson SR, McCollough CM. Dual-Energy CT for Evaluation of Intra- and Extracapsular Silicone Implant Rupture. Case Rep Radiol. 2016; 2016:6323709 Epub 2016 Jan 28
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  91. Breighner R, Holmes DR 3rd, Leng S, An KN, McCollough C, Zhao K. Relative accuracy of spin-image-based registration of partial capitate bones in 4DCT of the wrist. Comput Methods Biomech Biomed Eng Imaging Vis. 2016; 4 (6):360-367 Epub 2014 Aug 12
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  92. Wells ML, Froemming AT, Kawashima A, Vrtiska TJ, Kim B, Hartman RP, Holmes III DR, Carter RE, Bartley AC, Leng S, McCollough CH, Fletcher JG. A multi-reader in vitro study using porcine kidneys to determine the impact of integrated circuit detectors and iterative reconstruction on the detection accuracy, size measurement, and radiation dose for small (<4mm) renal stones Acta Radiologica.2016;0:(0)1-8.
  93. Chen B, Duan X, Yu Z, Leng S, Yu L, McCollough C. Technical Note: Development and validation of an open data format for CT projection data. Med Phys. 2015 Dec; 42 (12):6964-72
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