Publications

  1. Baffour FI, Rajendran K, Glazebrook KN, Thorne JE, Larson NB, Leng S, McCollough CH, Fletcher JG. Ultra-high-resolution imaging of the shoulder and pelvis using photon-counting-detector CT: a feasibility study in patients. Eur Radiol. 2022 Oct; 32 (10):7079-7086 Epub 2022 June 11
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  2. Rajiah PS, Weber N, Loewen J, Kasten H, Williamson E, Moore A, Leng S. Dynamic CT Angiography in Vascular Imaging: Principles and Applications. Radiographics. 2022 Sep 30; 210177 Epub 2022 Sept 30
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  3. Toia GV, Zamora D, Singleton M, Liu A, Tan E, Leng S, Shuman WP, Kanal KM, Mileto A. Detectability of Small Low-Attenuation Lesions With Deep Learning CT Image Reconstruction: A 24-Reader Phantom Study. AJR Am J Roentgenol. 2022 Sep 21 Epub 2022 Sept 21
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  4. Macielak RJ, Benson JC, Lane JI, Carlson ML, Leng S. Photon-Counting Detector CT for Temporal Bone Imaging: Up to Three Times the Resolution at Half the Radiation Dose. Otol Neurotol. 2022 Sep 16 Epub 2022 Sept 16
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  5. Baffour FI, Huber NR, Ferrero A, Rajendran K, Glazebrook KN, Larson NB, Kumar S, Cook JM, Leng S, Shanblatt ER, McCollough CH, Fletcher JG. Photon-counting Detector CT with Deep Learning Noise Reduction to Detect Multiple Myeloma. Radiology. 2022 Sep 6; 220311 Epub 2022 Sept 06
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  6. Huber NR, Ferrero A, Rajendran K, Baffour F, Glazebrook KN, Diehn FE, Inoue A, Fletcher JG, Yu L, Leng S, McCollough CH. Dedicated convolutional neural network for noise reduction in ultra-high-resolution photon-counting detector computed tomography. Phys Med Biol. 2022 Sep 2; 67 (17) Epub 2022 Sept 02
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  7. Esquivel A, Ferrero A, Mileto A, Baffour F, Horst K, Rajiah PS, Inoue A, Leng S, McCollough C, Fletcher JG. Photon-Counting Detector CT: Key Points Radiologists Should Know. Korean J Radiol. 2022 Sep; 23 (9):854-865
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  8. Pillai PS, Holmes DR 3rd, Carter R, Inoue A, Cook DA, Karwoski R, Fidler JL, Fletcher JG, Leng S, Yu L, McCollough CH, Hsieh SS. Individualized and generalized models for predicting observer performance on liver metastasis detection using CT. J Med Imaging (Bellingham). 2022 Sep; 9 (5):055501 Epub 2022 Sept 13
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  9. Gong H, Baffour FI, Glazebrook KN, Rhodes NG, Tiegs-Heiden CA, Thorne JE, Cook JM, Kumar S, Fletcher JG, McCollough CH, Leng S. Deep learning-based virtual noncalcium imaging in multiple myeloma using dual-energy CT. Med Phys. 2022 Aug 19 [Epub ahead of print]
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  10. Hsieh SS, Leng S, Yu L, Huber NR, McCollough CH. A minimum SNR criterion for computed tomography object detection in the projection domain. Med Phys. 2022 Aug; 49 (8):4988-4998 Epub 2022 July 10
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  11. Rajendran K, Baffour F, Powell G, Glazebrook K, Thorne J, Larson N, Leng S, McCollough C, Fletcher J. Improved visualization of the wrist at lower radiation dose with photon-counting-detector CT. Skeletal Radiol. 2022 Jul 13. [Epub ahead of print]
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  12. Tao S, Gong H, Michalak G, McCollough C, Leng S, Hu Y. Technical note: Evaluation of artificial 120-kilovolt computed tomography images for radiation therapy applications. Med Phys. 2022 Jun; 49 (6):3683-3691 Epub 2022 Apr 21
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  13. Mohammadinejad P, Khandelwal A, Inoue A, Takahashi H, Yalon M, Long Z, Halaweish AF, Leng S, Yu L, Lee YS, McCollough CH, Fletcher JG. Utility of an automatic adaptive iterative metal artifact reduction AiMAR algorithm in improving CT imaging of patients with hip prostheses evaluated for suspected bladder malignancy. Abdom Radiol (NY). 2022 Jun; 47 (6):2158-2167 Epub 2022 Mar 23
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  14. Inoue A, Johnson TF, White D, Cox CW, Hartman TE, Thorne JE, Shanblatt ER, Johnson MP, Carter RE, Lee YS, Rajendran K, Leng S, McCollough CH, Fletcher JG. Estimating the Clinical Impact of Photon-Counting-Detector CT in Diagnosing Usual Interstitial Pneumonia. Invest Radiol. 2022 May 06. [Epub ahead of print]
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  15. McCollough CH, McCollough SL, Schneider JJ, Moen TR, Weaver JM, Vrieze TJ, Yu L, Leng S. Dependence of Water-equivalent Diameter and Size-specific Dose Estimates on CT Tube Potential. Radiology. 2022 May; 303 (2):404-411 Epub 2022 Jan 18
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  16. Rajendran K, Petersilka M, Henning A, Shanblatt ER, Schmidt B, Flohr TG, Ferrero A, Baffour F, Diehn FE, Yu L, Rajiah P, Fletcher JG, Leng S, McCollough CH. First Clinical Photon-counting Detector CT System: Technical Evaluation. Radiology. 2022 Apr; 303 (1):130-138 Epub 2021 Dec 14
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  17. Benson JC, Rajendran K, Lane JI, Diehn FE, Weber NM, Thorne JE, Larson NB, Fletcher JG, McCollough CH, Leng S. A New Frontier in Temporal Bone Imaging: Photon-Counting Detector CT Demonstrates Superior Visualization of Critical Anatomic Structures at Reduced Radiation Dose. AJNR Am J Neuroradiol. 2022 Apr; 43 (4):579-584 Epub 2022 Mar 24
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  18. Ahmed Z, Rajendran K, Gong H, McCollough C, Leng S. Quantitative assessment of motion effects in dual-source dual-energy CT and dual-source photon-counting detector CT. Proc SPIE Int Soc Opt Eng. 2022 Feb-Mar; 12031 Epub 2022 Apr 04
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  19. Gong H, Ahmed Z, Jamison TE, Fletcher JG, McCollough CH, Leng S. Improving coronary artery imaging in single source CT with cardiac motion correction using attention and spatial transformer based neural networks. Proc SPIE Int Soc Opt Eng. 2022 Feb-Mar; 12031. Epub 2022 Apr 04.
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  20. VanMeter P, Marsh J Jr, Rajendran K, Leng S, McCollough C. Quantification of Coronary Calcification using High-Resolution Photon-Counting-Detector CT and an Image Domain Denoising Algorithm. Proc SPIE Int Soc Opt Eng. 2022 Feb-Mar; 12031 Epub 2022 Apr 04
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  21. Dunning CAS, Rajendran K, Fletcher JG, McCollough CH, Leng S. Impact of improved spatial resolution on radiomic features using photon-counting-detector CT. Proc SPIE Int Soc Opt Eng. 2022 Feb-Mar; 12032 Epub 2022 Apr 04
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  22. Gong H, Fletcher JG, Heiken JP, Wells ML, Leng S, McCollough CH, Yu L. Deep-learning model observer for a low-contrast hepatic metastases localization task in computed tomography. Med Phys. 2022 Jan; 49 (1):70-83 Epub 2021 Dec 01
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  23. Ray Chen J , Morris J , Wentworth A , Sears V , Duit A , Erie E , McGee K , Leng S . Quality assurance and printing accuracy analysis of 3D printing in medical applications. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2022; 12037:120370N
  24. Chang CW , Lei Y , Charyyev S , Leng S , Yoon T , Zhou J , Yang X , Lin L . An unsupervised patient-specific metal artifact reduction framework for proton therapy. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2022; 12034:120340X
  25. Nelson BJ , Leng S , Koenig T , McCollough CH . Complementary use of x-ray dark-field and attenuation computed tomography in quantifying pulmonary fibrosis in a mouse model. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2022; 12036:120360W
  26. Huber N, Anderson T, Missert A, Adkins M, Leng S, Fletcher J, McCollough C, Yu L, Glazebrook KN. Clinical evaluation of a phantom-based deep convolutional neural network for whole-body-low-dose and ultra-low-dose CT skeletal surveys. Skeletal Radiol. 2022 Jan; 51 (1):145-151 Epub 2021 June 10
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  27. Ahmed Z , Rajendran K , Gong H , McCollough C , Leng S . Quantitative assessment of motion effects in dual-source dual energy CT and dual-source photon-counting detector CT. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2022; 12031:120311P
  28. Inoue A, Vrtiska TJ, Lee YS, Vasconcelos RN, Weber NM, Halaweish AF, Duba I, Williamson EE, Leng S, McCollough CH, Fletcher JG. The feasibility of low iodine dynamic CT angiography with test bolus for evaluation of lower extremity peripheral artery disease. Vascular. 2021 Dec; 29 (6):927-937 Epub 2021 Jan 17
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  29. Gong H, Hsieh SS, Holmes DR 3rd, Cook DA, Inoue A, Bartlett DJ, Baffour F, Takahashi H, Leng S, Yu L, McCollough CH, Fletcher JG. An interactive eye-tracking system for measuring radiologists' visual fixations in volumetric CT images: Implementation and initial eye-tracking accuracy validation. Med Phys. 2021 Nov; 48 (11):6710-6723 Epub 2021 Oct 06
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  30. Rajendran K, Petersilka M, Henning A, Shanblatt E, Marsh J Jr, Thorne J, Schmidt B, Flohr T, Fletcher J, McCollough C, Leng S. Full field-of-view, high-resolution, photon-counting detector CT: technical assessment and initial patient experience. Phys Med Biol. 2021 Oct 27; 66(20).
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  31. Sandstedt M, Marsh J Jr, Rajendran K, Gong H, Tao S, Persson A, Leng S, McCollough C. Improved coronary calcification quantification using photon-counting-detector CT: an ex vivo study in cadaveric specimens. Eur Radiol. 2021 Sep; 31 (9):6621-6630 Epub 2021 Mar 13
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  32. Gong H, Marsh JF, D'Souza KN, Huber NR, Rajendran K, Fletcher JG, McCollough CH, Leng S. Deep-learning-based direct synthesis of low-energy virtual monoenergetic images with multi-energy CT. J Med Imaging (Bellingham). 2021 Sep; 8 (5):052104 Epub 2021 Apr 19
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  33. Mohammadinejad P, Mileto A, Yu L, Leng S, Guimaraes LS, Missert AD, Jensen CT, Gong H, McCollough CH, Fletcher JG. CT Noise-Reduction Methods for Lower-Dose Scanning: Strengths and Weaknesses of Iterative Reconstruction Algorithms and New Techniques. Radiographics. 2021 Sep-Oct; 41 (5):1493-1508
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  34. Gong H, Yu L, Leng S, Fletcher JG, McCollough CH. Reader Performance as a Function of Patient Size for the Detection of Hepatic Metastases. J Comput Assist Tomogr. 2021 Aug 2 Epub 2021 Aug 02
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  35. Ding YH, Abbasi M, Michalak G, Leng S, Dai D, Fitzgerald S, Kadirvel R, Kallmes DF, Brinjikji W. Characterization of thrombus composition with multimodality CT-based imaging: an in-vitro study. J Neurointerv Surg. 2021 Aug; 13 (8):738-740 Epub 2020 Oct 28
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  36. Gong H, Tao S, Gagneur JD, Liu W, Shen J, McCollough CH, Hu Y, Leng S. Implementation and experimental evaluation of Mega-voltage fan-beam CT using a linear accelerator. Radiat Oncol. 2021 Jul 28; 16 (1):139 Epub 2021 July 28
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  37. Gomez-Cardona D, Favazza CP, Leng S, Schueler BA, Fetterly KA. Task-specific efficient channel selection and bias management for Gabor function channelized Hotelling observer model for the assessment of x-ray angiography system performance. Med Phys. 2021 Jul; 48 (7):3638-3653 Epub 2021 May 30
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  38. Hsieh SS, Leng S, Rajendran K, Tao S, McCollough CH. Photon Counting CT: Clinical Applications and Future Developments. IEEE Trans Radiat Plasma Med Sci. 2021 Jul; 5 (4):441-452 Epub 2020 Aug 28
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  39. D'Souza RS, Li L, Leng S, Hunt C, Law L, Muir C, Eldrige J, Bydon M, Chi M, Shapiro S, Mauck WD, Qu W. A three-dimensional computed tomography study to determine the ideal method for fluoroscopically-guided bone marrow aspiration from the iliac crest. Bosn J Basic Med Sci. 2021 Jun 1; 21 (3):370-377 Epub 2021 June 01
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  40. Hu Y, Ding X, Shen J, Bues M, Liu W, Kang Y, Leng S, Yu L. Feasibility of using megavoltage computed tomography to reduce proton range uncertainty: A simulation study. J Appl Clin Med Phys. 2021 Mar; 22 (3):131-140 Epub 2021 Feb 20
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  41. Nelson BJ, Leng S, Shanblatt ER, McCollough CH, Koenig T. Empirical beam hardening and ring artifact correction for x-ray grating interferometry (EBHC-GI). Med Phys. 2021 Mar; 48 (3):1327-1340 Epub 2021 Jan 10
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  42. Tao S, Sheedy E, Bruesewitz M, Weber N, Williams K, Halaweish A, Schmidt B, Williamson E, McCollough C, Leng S. Technical Note: kV-independent coronary calcium scoring: A phantom evaluation of score accuracy and potential radiation dose reduction. Med Phys. 2021 Mar; 48 (3):1307-1314 Epub 2021 Jan 09
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  43. Moen TR, Chen B, Holmes DR 3rd, Duan X, Yu Z, Yu L, Leng S, Fletcher JG, McCollough CH. Low-dose CT image and projection dataset. Med Phys. 2021 Feb; 48 (2):902-911 Epub 2020 Dec 16
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  44. Long Z, Kurup AN, Jensen NM, Hangiandreou NJ, Schueler BA, Yu L, Leng S, Wood CP, Felmlee JP. Initial testing of pegfilgrastim (Neulasta Onpro) on-body injector in multiple radiological imaging environments. J Appl Clin Med Phys. 2021 Jan; 22 (1):343-349 Epub 2021 Jan 04
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  45. Charyyev S, Chang CW, Harms J, Oancea C, Yoon ST, Yang X, Zhang T, Zhou J, Leng S, Lin L. Accurate characterization of metal implants and human materials using novel proton counting detector for monte carlo dose calculation in proton therapy Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2021; 11595:115950B
  46. Inoue A, Johnson TF, Voss BA, Lee YS, Leng S, Koo CW, McCollough BD, Weaver JM, Gong H, Carter RE, McCollough CH, Fletcher JG. A Pilot Study to Estimate the Impact of High Matrix Image Reconstruction on Chest Computed Tomography. J Clin Imaging Sci. 2021; 11:52 Epub 2021 Sept 30
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  47. Gong H, Tao S, Rajendran K, Zhou W, McCollough CH, Leng S. Deep-learning-based direct inversion for material decomposition. Med Phys. 2020 Dec; 47 (12):6294-6309 Epub 2020 Oct 30
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  48. Fletcher JG, Levin DL, Sykes AG, Lindell RM, White DB, Kuzo RS, Suresh V, Yu L, Leng S, Holmes DR 3rd, Inoue A, Johnson MP, Carter RE, McCollough CH. Observer Performance for Detection of Pulmonary Nodules at Chest CT over a Large Range of Radiation Dose Levels. Radiology. 2020 Dec; 297 (3):699-707 Epub 2020 Sept 29
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  49. McCollough CH, Leng S. Use of artificial intelligence in computed tomography dose optimisation. Ann ICRP. 2020 Dec; 49 (1_suppl):113-125 Epub 2020 Sept 01
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  50. Tao S, Rajendran K, Zhou W, Fletcher JG, McCollough CH, Leng S. Noise reduction in CT image using prior knowledge aware iterative denoising. Phys Med Biol. 2020 Nov 19; 65 (22)
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  51. Rizvi A, Marcus RP, Guo Y, Carter R, Mark IT, Foley TA, Weber NM, Sheedy EN, Leng S, Williamson EE. Dynamic computed tomographic assessment of the mitral annulus in patients with and without mitral prolapse. J Cardiovasc Comput Tomogr. 2020 Nov - Dec; 14 (6):502-509 Epub 2020 Feb 27
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  52. Lee O, Rajendran K, Polster C, Stierstorfer K, Kappler S, Leng S, McCollough CH, Taguchi K. X-ray Transmittance Modeling-based Material Decomposition using a Photon-counting Detector CT System IEEE Transactions on Radiation and Plasma Medical Sciences. 2020.
  53. Li Z, Leng S, Halaweish AF, Yu Z, Yu L, Ritman EL, McCollough CH. Overcoming calcium blooming and improving the quantification accuracy of percent area luminal stenosis by material decomposition of multi-energy computed tomography datasets. J Med Imaging (Bellingham). 2020 Sep; 7 (5):053501 Epub 2020 Oct 01
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  54. Rajiah P, Parakh A, Kay F, Baruah D, Kambadakone AR, Leng S. Update on Multienergy CT: Physics, Principles, and Applications. Radiographics. 2020 Sep-Oct; 40 (5):1284-1308 Epub 2020 Aug 21
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  55. Tao S, Marsh JF, Tao A, Michalak GJ, Rajendran K, McCollough CH, Leng S. Multi-energy CT imaging for large patients using dual-source photon-counting detector CT. Phys Med Biol. 2020 Aug 31; 65 (17):17NT01
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  56. Jacobsen MC, Thrower SL, Ger RB, Leng S, Court LE, Brock KK, Tamm EP, Cressman ENK, Cody DD, Layman RR. Multi-energy computed tomography and material quantification: Current barriers and opportunities for advancement. Med Phys. 2020 Aug; 47 (8):3752-3771 Epub 2020 June 23
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  57. Gong H, Hu Q, Walther A, Koo CW, Takahashi EA, Levin DL, Johnson TF, Hora MJ, Leng S, Fletcher JG, McCollough CH, Yu L. Deep-learning-based model observer for a lung nodule detection task in computed tomography. J Med Imaging (Bellingham). 2020 Jul; 7 (4):042807 Epub 2020 June 30
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  58. Rajendran K, Murthy NS, Frick MA, Tao S, Unger MD, LaVallee KT, Larson NB, Leng S, Maus TP, McCollough CH. Quantitative Knee Arthrography in a Large Animal Model of Osteoarthritis Using Photon-Counting Detector CT. Invest Radiol. 2020 Jun; 55 (6):349-356
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  59. Taparra K, Lester SC, Harmsen WS, Petersen M, Funk RK, Blanchard MJ, Young P, Herrmann J, Hunzeker A, Schultz H, McCollough C, Tasson A, Leng S, Martenson JA, Whitaker TJ, Williamson E, Laack NN. Reducing Heart Dose with Protons and Cardiac Substructure Sparing for Mediastinal Lymphoma Treatment. Int J Part Ther. 2020 Summer; 7 (1):1-12 Epub 2020 Sept 04
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  60. Zhou W, Michalak GJ, Weaver JM, Gong H, Yu L, McCollough CH, Leng S. A Universal Protocol for Abdominal CT Examinations Performed on a Photon-Counting Detector CT System: A Feasibility Study. Invest Radiol. 2020 Apr; 55 (4):226-232
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  61. Lester SC, Taparra K, Petersen MM, Funk RK, Blanchard MJ, Young PM, Herrmann J, Hunzeker AE, Schultz HL, McCollough C, Tasson AM, Leng S, Martenson JA, Deisher AJ, Whitaker TJ, Williamson EE, Laack NN. Electrocardiogram-Gated Computed Tomography with Coronary Angiography for Cardiac Substructure Delineation and Sparing in Patients with Mediastinal Lymphomas Treated with Radiation Therapy. Pract Radiat Oncol. 2020 Mar - Apr; 10 (2):104-111 Epub 2019 Nov 26
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  62. Missert AD, Yu L, Leng S, Fletcher JG, McCollough CH. Synthesizing images from multiple kernels using a deep convolutional neural network. Med Phys. 2020 Feb; 47 (2):422-430 Epub 2019 Dec 29
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  63. Rajendran K, Voss BA, Zhou W, Tao S, DeLone DR, Lane JI, Weaver JM, Carlson ML, Fletcher JG, McCollough CH, Leng S. Dose Reduction for Sinus and Temporal Bone Imaging Using Photon-Counting Detector CT With an Additional Tin Filter. Invest Radiol. 2020 Feb; 55 (2):91-100
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  64. Marsh J Jr, Rajendran K, Tao S, Vercnocke A, Anderson J, Leng S, Ritman E, McCollough C. A Blooming correction technique for improved vasa vasorum detection using an ultra-high-resolution photon-counting detector CT. Proc SPIE Int Soc Opt Eng. 2020 Feb; 11312 Epub 2020 Mar 16
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  65. Baffour FI, Glazebrook KN, Morris JM, Michalak GJ, Fletcher JG, Leng S, McCollough CH. Clinical utility of virtual noncalcium dual-energy CT in imaging of the pelvis and hip. Skeletal Radiol. 2019 Dec; 48 (12):1833-1842 Epub 2019 May 30
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  66. Samei E, Bakalyar D, Boedeker KL, Brady S, Fan J, Leng S, Myers KJ, Popescu LM, Ramirez Giraldo JC, Ranallo F, Solomon J, Vaishnav J, Wang J. Performance evaluation of computed tomography systems: Summary of AAPM Task Group 233. Med Phys. 2019 Nov; 46 (11):e735-e756 Epub 2019 Sept 11
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  67. Fletcher JG, DeLone DR, Kotsenas AL, Campeau NG, Lehman VT, Yu L, Leng S, Holmes DR 3rd, Edwards PK, Johnson MP, Michalak GJ, Carter RE, McCollough CH. Evaluation of Lower-Dose Spiral Head CT for Detection of Intracranial Findings Causing Neurologic Deficits. AJNR Am J Neuroradiol. 2019 Nov; 40 (11):1855-1863 Epub 2019 Oct 24
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  68. Sheikhzadeh M, Vercnocke AJ, Tao S, Rajendran K, Leng S, Ritman EL, McCollough CH. Impact of Effective Detector Pixel and CT Voxel Size on Accurate Estimation of Blood Volume in Opacified Microvasculature. Acad Radiol. 2019 Oct; 26 (10):1410-1416 Epub 2018 Dec 07
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  69. Navin PJ, Kim B, Wells ML, Khandelwal A, Halaweish AF, Moen TR, Johnson MP, McCollough S, Lee YS, Leng S, McCollough CH, Fletcher JG. Reducing radiation dose for multi-phase contrast-enhanced dual energy renal CT: pilot study evaluating prior iterative reconstruction. Abdom Radiol (NY). 2019 Oct; 44 (10):3350-3358
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  70. Zhou W, Michalak G, Weaver J, Ferrero A, Gong H, Fetterly KA, McCollough CH, Leng S. Determination of iodine detectability in different types of multiple-energy images for a photon-counting detector computed tomography system. J Med Imaging (Bellingham). 2019 Oct; 6 (4):043501 Epub 2019 Oct 15
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  71. Tao S, Rajendran K, McCollough CH, Leng S. Feasibility of multi-contrast imaging on dual-source photon counting detector (PCD) CT: An initial phantom study. Med Phys. 2019 Sep; 46 (9):4105-4115 Epub 2019 July 05
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  72. Morris J, Michalak G, Leng S, Moynagh M, Kurup AN, McCollough C, Fletcher J. Dual-Energy CT Monitoring of Cryoablation Zone Growth in the Spinal Column and Bony Pelvis: A Laboratory Study. J Vasc Interv Radiol. 2019 Sep; 30 (9):1496-1503 Epub 2019 May 18
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  73. Tao A, Huang R, Tao S, Michalak GJ, McCollough CH, Leng S. Dual-source photon counting detector CT with a tin filter: a phantom study on iodine quantification performance. Phys Med Biol. 2019 May 31; 64 (11):115019
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  74. Tao S, Rajendran K, Zhou W, Fletcher JG, McCollough CH, Leng S. Improving iodine contrast to noise ratio using virtual monoenergetic imaging and prior-knowledge-aware iterative denoising (mono-PKAID). Phys Med Biol. 2019 May 16; 64 (10):105014
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  75. Dilger SKN, Yu L, Chen B, Favazza CP, Carter RE, Fletcher JG, McCollough CH, Leng S. Localization of liver lesions in abdominal CT imaging: I. Correlation of human observer performance between anatomical and uniform backgrounds. Phys Med Biol. 2019 May 10; 64 (10):105011
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  76. Dilger SKN, Leng S, Chen B, Carter RE, Favazza CP, Fletcher JG, McCollough CH, Yu L. Localization of liver lesions in abdominal CT imaging: II. Mathematical model observer performance correlates with human observer performance for localization of liver lesions in abdominal CT imaging. Phys Med Biol. 2019 May 10; 64 (10):105012
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  77. Gong H, Yu L, Leng S, Dilger SK, Ren L, Zhou W, Fletcher JG, McCollough CH. A deep learning- and partial least square regression-based model observer for a low-contrast lesion detection task in CT. Med Phys. 2019 May; 46 (5):2052-2063 Epub 2019 Apr 01
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  78. Leng S, Bruesewitz M, Tao S, Rajendran K, Halaweish AF, Campeau NG, Fletcher JG, McCollough CH. Photon-counting Detector CT: System Design and Clinical Applications of an Emerging Technology. Radiographics. 2019 May-Jun; 39 (3):729-743
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  79. Glazebrook KN, Doerge S, Leng S, Drees TA, Hunt KN, Zingula SN, Pruthi S, Geske JR, Carter RE, McCollough CH, Fletcher JG. Ability of Dual-Energy CT to Detect Silicone Gel Breast Implant Rupture and Nodal Silicone Spread. AJR Am J Roentgenol. 2019 Apr; 212 (4):933-942 Epub 2019 Feb 19
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  80. Zhou W, Bartlett DJ, Diehn FE, Glazebrook KN, Kotsenas AL, Carter RE, Fletcher JG, McCollough CH, Leng S. Reduction of Metal Artifacts and Improvement in Dose Efficiency Using Photon-Counting Detector Computed Tomography and Tin Filtration. Invest Radiol. 2019 Apr; 54 (4):204-211
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  81. Bartlett DJ, Koo CW, Bartholmai BJ, Rajendran K, Weaver JM, Halaweish AF, Leng S, McCollough CH, Fletcher JG. High-Resolution Chest Computed Tomography Imaging of the Lungs: Impact of 1024 Matrix Reconstruction and Photon-Counting Detector Computed Tomography. Invest Radiol. 2019 Mar; 54 (3):129-137
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  82. Shanblatt ER, Sung Y, Gupta R, Nelson BJ, Leng S, Graves WS, McCollough CH. Forward model for propagation-based x-ray phase contrast imaging in parallel- and cone-beam geometry. Opt Express. 2019 Feb 18; 27 (4):4504-4521
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  83. Gomez-Cardona D, Leng S, Favazza CP, Schueler BA, Fetterly KA. Automatic strategy for CHO channel reduction in x-ray angiography systems Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2019; 10952:1095205
  84. Marcus RP, Fletcher JG, Ferrero A, Leng S, Halaweish AF, Gutjahr R, Vrtiska TJ, Wells ML, Enders FT, McCollough CH. Detection and Characterization of Renal Stones by Using Photon-Counting-based CT. Radiology. 2018 Nov; 289 (2):436-442 Epub 2018 Aug 07
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  85. Fletcher JG, Fidler JL, Venkatesh SK, Hough DM, Takahashi N, Yu L, Johnson M, Leng S, Holmes DR 3rd, Carter R, McCollough CH. Observer Performance with Varying Radiation Dose and Reconstruction Methods for Detection of Hepatic Metastases. Radiology. 2018 Nov; 289 (2):455-464 Epub 2018 Sept 11
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  86. Leng S, Rajendran K, Gong H, Zhou W, Halaweish AF, Henning A, Kappler S, Baer M, Fletcher JG, McCollough CH. 150-mum Spatial Resolution Using Photon-Counting Detector Computed Tomography Technology: Technical Performance and First Patient Images. Invest Radiol. 2018 Nov; 53 (11):655-662
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  87. Marsh JF, Jorgensen SM, Rundle DS, Vercnocke AJ, Leng S, Butler PH, McCollough CH, Ritman EL. Evaluation of a photon counting Medipix3RX cadmium zinc telluride spectral x-ray detector. J Med Imaging (Bellingham). 2018 Oct; 5 (4):043503 Epub 2018 Dec 04
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  88. Leng S. Radiation Dose in CT-guided Interventional Procedures: Establishing a Benchmark. Radiology 2018 Oct; 289 (1):158-159 Epub 2018 July 17
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  89. Ferrero A, Gutjahr R, Halaweish AF, Leng S, McCollough CH. Characterization of Urinary Stone Composition by Use of Whole-body, Photon-counting Detector CT. Acad Radiol. 2018 Oct; 25 (10):1270-1276 Epub 2018 Feb 14
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  90. Tao S, Rajendran K, McCollough CH, Leng S. Material decomposition with prior knowledge aware iterative denoising (MD-PKAID). Phys Med Biol. 2018 Sep 21; 63 (19):195003 Epub 2018 Sept 21
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  91. Zhou W, Lane JI, Carlson ML, Bruesewitz MR, Witte RJ, Koeller KK, Eckel LJ, Carter RE, McCollough CH, Leng S. Comparison of a Photon-Counting-Detector CT with an Energy-Integrating-Detector CT for Temporal Bone Imaging: A Cadaveric Study. AJNR Am J Neuroradiol. 2018 Sep; 39 (9):1733-1738 Epub 2018 Aug 09
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  92. Samreen N, Glazebrook KN, Bhatt A, Venkatesh SK, McMenomy BP, Chandra A, Leng S, Adler KE, McCollough CH. Imaging findings of mammary and systemic silicone deposition secondary to breast implants. Br J Radiol. 2018 Sep; 91 (1089):20180098 Epub 2018 May 10
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  93. Yu L, Ren L, Li Z, Leng S, McCollough CH. Dual-source multienergy CT with triple or quadruple x-ray beams. J Med Imaging (Bellingham). 2018 Jul; 5 (3):033502 Epub 2018 July 24
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