Publications

  1. Malouff TD, Mahajan A, Mutter RW, Krishnan S, Hoppe BS, Beltran C, Trifiletti DM, Vallow LA. Carbon ion radiation therapy in breast cancer: a new frontier. Breast Cancer Res Treat. 2020 Jun; 181 (2):291-296 Epub 2020 Apr 21
    View PubMed
  2. Zhou Q, Huang J, Zhang C, Zhao F, Kim W, Tu X, Zhang Y, Nowsheen S, Zhu Q, Deng M, Chen Y, Qin B, Luo K, Liu B, Lou Z, Mutter RW, Yuan J. The bromodomain containing protein BRD-9 orchestrates RAD51-RAD54 complex formation and regulates homologous recombination-mediated repair. Nat Commun. 2020 May 26; 11 (1):2639
    View PubMed
  3. Ho AY, Wright JL, Blitzblau RC, Mutter RW, Duda DG, Norton L, Bardia A, Spring L, Isakoff SJ, Chen JH, Grassberger C, Bellon JR, Beriwal S, Khan AJ, Speers C, Dunn SA, Thompson A, Santa-Maria CA, Krop IE, Mittendorf E, King TA, Gupta GP. Optimizing Radiotherapy to Boost Systemic Immune Responses in Breast Cancer: A Critical Review for Breast Radiation Oncologists. Int J Radiat Oncol Biol Phys. 2020 May 14 [Epub ahead of print]
    View PubMed
  4. Mutter RW, Jethwa KR, Wan Chan Tseung HS, Wick SM, Kahila MMH, Viehman JK, Shumway DA, Corbin KS, Park SS, Remmes NB, Whitaker TJ, Beltran CJ. Incorporation of Biologic Response Variance Modeling Into the Clinic: Limiting Risk of Brachial Plexopathy and Other Late Effects of Breast Cancer Proton Beam Therapy. Pract Radiat Oncol. 2020 Mar - Apr; 10 (2):e71-e81 Epub 2019 Sept 05
    View PubMed
  5. Yadav S, Karam D, Bin Riaz I, Xie H, Durani U, Duma N, Giridhar KV, Hieken TJ, Boughey JC, Mutter RW, Hawse JR, Jimenez RE, Couch FJ, Leon-Ferre RA, Ruddy KJ. Male breast cancer in the United States: Treatment patterns and prognostic factors in the 21st century. Cancer. 2020 Jan 1; 126 (1):26-36 Epub 2019 Oct 07
    View PubMed
  6. Ma DJ, Price KA, Moore EJ, Patel SH, Hinni ML, Garcia JJ, Graner DE, Neben-Wittich M, Garces YI, Chintakuntlawar AV, Price DL, Van Abel KM, Kasperbauer JL, Janus JR, Waddle M, Miller RC, Shiraishi S, Mutter RW, Corbin KS, Park SS, Foote RL. Reply to A.S. Garden. J Clin Oncol 2019 Dec 20; 37 (36):3559-3560 Epub 2019 Sept 26
    View PubMed
  7. Mutter RW, Jethwa KR, Gonuguntla K, Remmes NB, Whitaker TJ, Hieken TJ, Ruddy KJ, McGee LA, Corbin KS, Park SS. 3 fraction pencil-beam scanning proton accelerated partial breast irradiation: early provider and patient reported outcomes of a novel regimen. Radiat Oncol. 2019 Nov 21; 14 (1):211
    View PubMed
  8. Smith NL, Jethwa KR, Viehman JK, Harmsen WS, Gonuguntla K, Elswick SM, Grauberger JN, Amundson AC, Whitaker TJ, Remmes NB, Harless CA, Boughey JC, Nguyen MT, Park SS, Corbin KS, Mutter RW. Post-mastectomy intensity modulated proton therapy after immediate breast reconstruction: Initial report of reconstruction outcomes and predictors of complications. Radiother Oncol. 2019 Nov; 140:76-83 Epub 2019 June 08
    View PubMed
  9. Bekelman JE, Lu H, Pugh S, Baker K, Berg CD, de Gonzalez AB, Braunstein LZ, Bosch W, Chauhan C, Ellenberg S, Fang LC, Freedman GM, Hahn EA, Haffty BG, Khan AJ, Jimenez RB, Kesslering C, Ky B, Lee C, Lu HM, Mishra MV, Mullins CD, Mutter RW, Nagda S, Pankuch M, Powell SN, Prior FW, Schupak K, Taghian AG, Wilkinson JB, MacDonald SM, Cahlon O, RadComp (Radiotherapy Comparative Effectiveness Consortium). Pragmatic randomised clinical trial of proton versus photon therapy for patients with non-metastatic breast cancer: the Radiotherapy Comparative Effectiveness (RadComp) Consortium trial protocol. BMJ Open. 2019 Oct 15; 9 (10):e025556
    View PubMed
  10. Jethwa KR, Park SS, Gonuguntla K, Wick SM, Vallow LA, Deufel CL, Whitaker TJ, Furutani KM, Ruddy KJ, Corbin KS, Hieken TJ, Mutter RW. In Reply to Hannoun-Levi and Hannoun. Int J Radiat Oncol Biol Phys 2019 Aug 1; 104 (5):1177-1179 Epub 2019 Apr 27
    View PubMed
  11. Tu X, Qin B, Zhang Y, Zhang C, Kahila M, Nowsheen S, Yin P, Yuan J, Pei H, Li H, Yu J, Song Z, Zhou Q, Zhao F, Liu J, Zhang C, Dong H, Mutter RW, Lou Z. PD-L1 (B7-H1) Competes with the RNA Exosome to Regulate the DNA Damage Response and Can Be Targeted to Sensitize to Radiation or Chemotherapy. Mol Cell. 2019 Jun 20; 74 (6):1215-1226.e4 Epub 2019 Apr 30
    View PubMed
  12. Jethwa KR, Park SS, Gonuguntla K, Wick SM, Vallow LA, Deufel CL, Whitaker TJ, Furutani KM, Ruddy KJ, Corbin KS, Hieken TJ, Mutter RW. Three-Fraction Intracavitary Accelerated Partial Breast Brachytherapy: Early Provider and Patient-Reported Outcomes of a Novel Regimen. Int J Radiat Oncol Biol Phys. 2019 May 1; 104 (1):75-82 Epub 2018 Dec 21
    View PubMed
  13. Sio TT, Atherton PJ, Pederson LD, Zhen WK, Mutter RW, Garces YI, Ma DJ, Leenstra JL, Rwigema JM, Dakhil S, Bearden JD, van der Veen SJ, Ganti AK, Schild SE, Miller RC. Daily Lisinopril vs Placebo for Prevention of Chemoradiation-Induced Pulmonary Distress in Patients With Lung Cancer (Alliance MC1221): A Pilot Double-Blind Randomized Trial. Int J Radiat Oncol Biol Phys. 2019 Mar 1; 103 (3):686-696 Epub 2018 Nov 02
    View PubMed
  14. Zhang Y, Mutter RW, Park SS, Hieken TJ, Yan ES, Corbin KS, Brinkmann DH, Pafundi DH. Carbon Fiducial Image Guidance Increases the Accuracy of Lumpectomy Cavity Localization in Radiation Therapy for Breast Cancer. Pract Radiat Oncol. 2019 Jan; 9 (1):e14-e21 Epub 2018 Oct 01
    View PubMed
  15. Leon-Ferre RA, Giridhar KV, Hieken TJ, Mutter RW, Couch FJ, Jimenez RE, Hawse JR, Boughey JC, Ruddy KJ. A contemporary review of male breast cancer: current evidence and unanswered questions. Cancer Metastasis Rev. 2018 Dec; 37 (4):599-614
    View PubMed
  16. Tu X, Kahila MM, Zhou Q, Yu J, Kalari KR, Wang L, Harmsen WS, Yuan J, Boughey JC, Goetz MP, Sarkaria JN, Lou Z, Mutter RW. ATR Inhibition Is a Promising Radiosensitizing Strategy for Triple-Negative Breast Cancer. Mol Cancer Ther. 2018 Nov; 17 (11):2462-2472 Epub 2018 Aug 30
    View PubMed
  17. Gao RW, Park SS, Jakub JW, Hieken TJ, Conners AL, Neal L, Pruthi S, Corbin KS, Yan ES, Mutter RW, Stish BJ. Durable response of early-stage breast cancer to bilateral definitive SBRT in a medically inoperable patient. Pract Radiat Oncol. 2018 Nov - Dec; 8 (6):361-365 Epub 2018 Mar 18
    View PubMed
  18. Leal AD, Van Houten H, Sangaralingham L, Freedman RA, Jemal A, Neuman HB, Haddad TC, Mutter RW, Keegan THM, Mougalian SS, Loprinzi CL, Gross CP, Shah N, Ruddy KJ. Breast Cancer Survivorship Care Variations Between Adjuvant Chemotherapy Regimens. Clin Breast Cancer. 2018 Aug; 18 (4):e513-e520 Epub 2017 Sept 22
    View PubMed
  19. Elswick SM, Harless CA, Bishop SN, Schleck CD, Mandrekar J, Reusche RD, Mutter RW, Boughey JC, Jacobson SR, Lemaine V. Prepectoral Implant-Based Breast Reconstruction with Postmastectomy Radiation Therapy. Plast Reconstr Surg. 2018 Jul; 142 (1):1-12
    View PubMed
  20. Jethwa KR, Kahila MM, Mara KC, Harmsen WS, Routman DM, Pumper GM, Corbin KS, Sloan JA, Ruddy KJ, Hieken TJ, Park SS, Mutter RW. Patient-reported outcomes of catheter-based accelerated partial breast brachytherapy and whole breast irradiation, a single institution experience. Breast Cancer Res Treat. 2018 May; 169 (1):189-196 Epub 2018 Jan 18
    View PubMed
  21. Corbin CS, Mutter RW. Proton therapy for breast cancer: progress & pitfalls Breast Cancer Management. 2018; 7(1).
  22. Gast KC, Viscuse PV, Nowsheen S, Haddad TC, Mutter RW, Wahner Hendrickson AE, Couch FJ, Ruddy KJ. Cardiovascular Concerns in BRCA1 and BRCA2 Mutation Carriers. Curr Treat Options Cardiovasc Med. 2018 Mar 1; 20 (2):18 Epub 2018 Mar 01
    View PubMed
  23. Glorioso JM, Gonzalez Juarrero AB, Rodysill BR, Harmsen WS, Habermann EB, Carter JM, Mutter RW, Degnim AC, Jakub JW. Margin Proximity Correlates with Local Recurrence After Mastectomy for Patients Not Receiving Adjuvant Radiotherapy. Ann Surg Oncol. 2017 Oct; 24 (11):3148-3156 Epub 2017 July 05
    View PubMed
  24. Mutter RW, Remmes NB, Kahila MM, Hoeft KA, Pafundi DH, Zhang Y, Corbin KS, Park SS, Yan ES, Lemaine V, Boughey JC, Beltran CJ. Initial clinical experience of postmastectomy intensity modulated proton therapy in patients with breast expanders with metallic ports. Pract Radiat Oncol. 2017 Jul - Aug; 7 (4):e243-e252 Epub 2016 Dec 16
    View PubMed
  25. Jethwa KR, Kahila MM, Whitaker TJ, Harmsen WS, Corbin KS, Park SS, Yan ES, Lemaine V, Boughey JC, Mutter RW. Immediate tissue expander or implant-based breast reconstruction does not compromise the oncologic delivery of post-mastectomy radiotherapy (PMRT). Breast Cancer Res Treat. 2017 Jul; 164 (1):237-244 Epub 2017 Apr 17
    View PubMed
  26. Mutter RW, Riaz N, Ng CK, Delsite R, Piscuoglio S, Edelweiss M, Martelotto LG, Sakr RA, King TA, Giri DD, Drobnjak M, Brogi E, Bindra R, Bernheim G, Lim RS, Blecua P, Desrichard A, Higginson D, Towers R, Jiang R, Lee W, Weigelt B, Reis-Filho JS, Powell SN. Bi-allelic alterations in DNA repair genes underpin homologous recombination DNA repair defects in breast cancer. J Pathol. 2017 Jun; 242 (2):165-177 Epub 2017 Apr 27
    View PubMed
  27. Jethwa KR, Kahila MM, Hunt KN, Brown LC, Corbin KS, Park SS, Yan ES, Boughey JC, Mutter RW. Delineation of Internal Mammary Nodal Target Volumes in Breast Cancer Radiation Therapy. Int J Radiat Oncol Biol Phys. 2017 Mar 15; 97 (4):762-769 Epub 2016 Nov 27
    View PubMed
  28. Kuerer HM, Cordeiro PG, Mutter RW. Optimizing Breast Cancer Adjuvant Radiation and Integration of Breast and Reconstructive Surgery. Am Soc Clin Oncol Educ Book. 2017; 37:93-105
    View PubMed
  29. Hieken TJ, Mutter RW, Jakub JW, Boughey JC, Degnim AC, Sukov WR, Childs S, Corbin KS, Furutani KM, Whitaker TJ, Park SS. A novel treatment schedule for rapid completion of surgery and radiation in early-stage breast cancer (vol 23, pg 3297, 2016) Annals Of Surgical Oncology. 2016 Dec; 23: S1059.
  30. Hieken TJ, Mutter RW, Jakub JW, Boughey JC, Degnim AC, Sukov WR, Childs S, Corbin KS, Furutani KM, Whitaker TJ, Park SS. Erratum to: A Novel Treatment Schedule for Rapid Completion of Surgery and Radiation in Early-Stage Breast Cancer. Ann Surg Oncol. 2016 Dec; 23 (Suppl 5):1059
    View PubMed
  31. Stish BJ, Pafundi DH, Hieken TJ, Whitaker TJ, Furutani KM, Jakub JW, Boughey JC, Degnim AC, McLemore LB, Mou B, Mutter RW, Park SS. Feasibility and full-course dosimetry of an intraoperatively placed multichannel brachytherapy catheter for accelerated partial breast irradiation Brachytherapy. 2016 Nov-dec; 15(6):796-803. Epub 1900 Jan 01.
    View PubMed
  32. Stish BJ, Pafundi DH, Hieken TJ, Whitaker TJ, Furutani KM, Jakub JW, Boughey JC, Degnim AC, McLemore LB, Mou B, Mutter RW, Park SS. Feasibility and full-course dosimetry of an intraoperatively placed multichannel brachytherapy catheter for accelerated partial breast irradiation. Brachytherapy. 2016 Nov - Dec; 15 (6):796-803 Epub 2016 Sept 07
    View PubMed
  33. Hieken TJ, Mutter RW, Jakub JW, Boughey JC, Degnim AC, Sukov WR, Childs S, Corbin KS, Furutani KM, Whitaker TJ, Park SS. A Novel Treatment Schedule for Rapid Completion of Surgery and Radiation in Early-Stage Breast Cancer. Ann Surg Oncol. 2016 Oct; 23 (10):3297-303 Epub 2016 June 22
    View PubMed
  34. Mayo CS, Pisansky TM, Petersen IA, Yan ES, Davis BJ, Stafford SL, Garces YI, Miller RC, Martenson JA, Mutter RW, Choo R, Hallemeier CL, Laack NN, Ma DJ, Olivier KR, Keole SR, Fatyga M, Foote RL, Haddock MG. Establishment of practice standards in nomenclature and prescription to enable construction of software and databases for knowledge-based practice review. Pract Radiat Oncol. 2016 Jul-Aug; 6 (4):e117-e126 Epub 2016 Jan 26
    View PubMed
  35. Mutter RW, Frost MH, Hoskin TL, Johnson JL, Hartmann LC, Boughey JC. Breast cancer after prophylactic mastectomy (bilateral or contralateral prophylactic mastectomy), a clinical entity: presentation, management, and outcomes. Breast Cancer Res Treat. 2015 Aug; 153: (1)183-90.
    View PubMed
  36. Brown LC, Diehn FE, Boughey JC, Childs SK, Park SS, Yan ES, Petersen IA, Mutter RW. Delineation of Supraclavicular Target Volumes in Breast Cancer Radiation Therapy. Int J Radiat Oncol Biol Phys. 2015 Jul 1; 92 (3):642-9 Epub 2015 Apr 28
    View PubMed
  37. Brown LC, Mutter RW, Halyard MY. Benefits, risks, and safety of external beam radiation therapy for breast cancer. Int J Womens Health. 2015; 7:449-58 Epub 2015 Apr 24
    View PubMed
  38. Brown L, Harmsen W, Blanchard M, Goetz M, Jakub J, Mutter R, Petersen I, Rooney J, Stauder M, Yan E, Laack N. Once-daily radiation therapy for inflammatory breast cancer. Int J Radiat Oncol Biol Phys. 2014 Aug 1; 89 (5):997-1003 Epub 2014 Apr 07
    View PubMed
  39. Dad L, Shah MM, Mutter R, Olsen J, Dominello M, Miller SM, Fisher B, Lee N, Komaki R. Why target the globe?: 4-year report (2009-2013) of the Association of Residents in Radiation Oncology Global Health Initiative. Int J Radiat Oncol Biol Phys. 2014 Jul 1; 89 (3):485-91
    View PubMed
  40. Fisher BJ, Daugherty LC, Einck JP, Suneja G, Shah MM, Dad LK, Mutter RW, Wilkinson JB, Mundt AJ. Radiation oncology in Africa: improving access to cancer care on the African continent. Int J Radiat Oncol Biol Phys. 2014 Jul 1; 89 (3):458-61
    View PubMed
  41. Mutter RW, Lok BH, Dutta PR, Riaz N, Setton J, Berry SL, Goenka A, Zhang ZG, Rao SS, Wolden SL, Lee NY. Constraining the brachial plexus does not compromise regional control in oropharyngeal carcinoma Radiation Oncology. 2013 Jul 9; 8:173.
    View PubMed
  42. Lok B, Khan S, Mutter R, Liu J, Fields R, Pulitzer M, Shi W, Zhang Z, Kraus D, Pfister D, Busam KJ, Brownell I, Lee N. Selective radiotherapy for the treatment of head and neck Merkel cell carcinoma. Cancer. 2012 Aug 15; 118(16):3937-44. Epub 2011 Dec 16.
    View PubMed
  43. Mutter RW, Liu F, Abreu A, Yorke E, Jackson A, Rosenzweig KE. Dose-volume parameters predict for the development of chest wall pain after stereotactic body radiation for lung cancer. Int J Radiat Oncol Biol Phys. 2012 Apr 1; 82(5):1783-90. Epub 2011 Aug 23.
    View PubMed
  44. Mutter RW, Singer S, Zhang Z, Brennan MF, Alektiar KM. The enigma of myxofibrosarcoma of the extremity. Cancer. 2012 Jan 15; 118(2):518-27. Epub 2011 Jun 29.
    View PubMed
  45. Barker CA, Mutter RW, Shapiro LQ, Zhang Z, Wolden SL, Yahalom J. Contrast media use in radiation oncology: a prospective, controlled educational intervention study with retrospective analysis of patient outcomes. J Am Coll Radiol. 2010 Dec; 7(12):967-74.
    View PubMed
  46. Mutter R, Lu B, Carbone DP, Csiki I, Moretti L, Johnson DH, Morrow JD, Sandler AB, Shyr Y, Ye F, Choy H. A phase II study of celecoxib in combination with paclitaxel, carboplatin, and radiotherapy for patients with inoperable stage IIIA/B non-small cell lung cancer. Clin Cancer Res. 2009 Mar 15; 15(6):2158-65. Epub 2009 Mar 10.
    View PubMed
  47. Kim KW, Mutter RW, Willey CD, Subhawong TK, Shinohara ET, Albert JM, Ling G, Cao C, Gi YJ, Lu B. Inhibition of survivin and aurora B kinase sensitizes mesothelioma cells by enhancing mitotic arrests. Int J Radiat Oncol Biol Phys. 2007 Apr 1; 67(5):1519-25.
    View PubMed
  48. Kim KW, Mutter RW, Cao C, Albert JM, Freeman M, Hallahan DE, Lu B. Autophagy for cancer therapy through inhibition of pro-apoptotic proteins and mammalian target of rapamycin signaling. J Biol Chem. 2006 Dec 1; 281(48):36883-90. Epub 2006 Sep 27
    View PubMed
  49. Kim KW, Mutter RW, Cao C, Albert JM, Shinohara ET, Sekhar KR, Lu B. Inhibition of signal transducer and activator of transcription 3 activity results in down-regulation of Survivin following irradiation. Mol Cancer Ther. 2006 Nov; 5(11):2659-65.
    View PubMed
  50. Schadt CR, Cox KL, Tramontana MG, Byrne DW, Davis TL, Fang JY, Konrad PE, Padaliya B, Mutter RW, Gill CE, Richardson CR, Charles PD. Depression and intelligence in patients with Parkinson's disease and deep-brain stimulation. J Natl Med Assoc. 2006 Jul; 98(7):1121-5.
    View PubMed