Publications

  1. Alto A, Natesampillai S, Chandrasekar AP, Krogman A, Misra A, Shweta FNU, VanLith C, Yao JD, Cummins NW, Badley AD. The combination of venetoclax and ixazomib selectively and efficiently kills HIV infected cell lines, but has unacceptable toxicity in primary cell models. J Virol. 2021 Apr 7 Epub 2021 Apr 07
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  2. Cummins NW. Remdesivir: An antiviral still seeking a raison d'etre. Clin Infect Dis. 2021 Mar 22 [Epub ahead of print]
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  3. Jeffery MM, Cummins NW, Dempsey TM, Limper AH, Shah ND, Bellolio F. Association of outpatient ACE inhibitors and angiotensin receptor blockers and outcomes of acute respiratory illness: a retrospective cohort study. BMJ Open. 2021 Mar 17; 11 (3):e044010
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  4. Pereira NL, Ahmad F, Byku M, Cummins NW, Morris AA, Owens A, Tuteja S, Cresci S. COVID-19: Understanding Inter-Individual Variability and Implications for Precision Medicine. Mayo Clin Proc. 2021 Feb; 96 (2):446-463 Epub 2020 Dec 03
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  5. corsini campioli c, esquer garrigos z, assi m, go john, razonable r, beam e, yao j, cummins n. Transient Hepatitis B Surface Antigenemia Following Immunization with Heplisav-B Mayo Clinic Proceedings: Innovations, Quality & Outcomes. 2021.
  6. Sangarlangkarn A, Rizza SA, Mahmood M, Cummins NW, Temesgen Z. A National Survey of Provider's Preparedness to Care for Persons Living With HIV Aged >/=50 Years. J Contin Educ Health Prof. 2021 Jan 1; 41 (1):82-84
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  7. Aboulnasr F, Krogman A, Graham RP, Cummins NW, Misra A, Garcia-Rivera E, Anderson JR, Natesampillai S, Kogan N, Aravamudan M, Nie Z, Chung TDY, Buick R, Feldman AL, King RL, Novak AJ, Ansell SM, Kenderian S, Badley AD. Human Cancers Express TRAILshort, a Dominant Negative TRAIL Splice Variant, Which Impairs Immune Effector Cell Killing of Tumor Cells. Clin Cancer Res 2020 Nov 1; 26 (21):5759-5771 Epub 2020 July 15
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  8. French AJ, Natesampillai S, Krogman A, Correia C, Peterson KL, Alto A, Chandrasekar AP, Misra A, Li Y, Kaufmann SH, Badley AD, Cummins NW. Reactivating latent HIV with PKC agonists induces resistance to apoptosis and is associated with phosphorylation and activation of BCL2. PLoS Pathog. 2020 Oct; 16 (10):e1008906 Epub 2020 Oct 19
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  9. Meagher KM, Cummins NW, Bharucha AE, Badley AD, Chlan LL, Wright RS. COVID-19 Ethics and Research. Mayo Clin Proc. 2020 Jun; 95 (6):1119-1123 Epub 2020 Apr 24
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  10. Paim AC, Badley AD, Cummins NW. Mechanisms of Human Immunodeficiency Virus-Associated Lymphocyte Regulated Cell Death. AIDS Res Hum Retroviruses. 2020 Feb; 36 (2):101-115 Epub 2019 Dec 10
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  11. Chandrasekar AP, Cummins NW, Badley AD. The Role of the BCL-2 Family of Proteins in HIV-1 Pathogenesis and Persistence. Clin Microbiol Rev. 2019 Dec 18; 33 (1) Epub 2019 Oct 30
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  12. Paim AC, Cummins NW, Natesampillai S, Garcia-Rivera E, Kogan N, Neogi U, Sonnerborg A, Sperk M, Bren GD, Deeks S, Polley E, Badley AD. HIV elite control is associated with reduced TRAILshort expression. AIDS. 2019 Sep 1; 33 (11):1757-1763
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  13. Natesampillai S, Paim AC, Cummins NW, Chandrasekar AP, Bren GD, Lewin SR, Kiem HP, Badley AD. TRAILshort Protects against CD4 T Cell Death during Acute HIV Infection. J Immunol. 2019 Aug 1; 203 (3):718-724 Epub 2019 June 12
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  14. Arslan S, Litzow MR, Cummins NW, Rizza SA, Badley AD, Navarro W, Hashmi SK. Risks and Outcomes of Allogeneic Hematopoietic Stem Cell Transplantation for Hematologic Malignancies in Patients with HIV Infection. Biol Blood Marrow Transplant. 2019 Aug; 25 (8):e260-e267 Epub 2019 Mar 26
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  15. Paim AC, Rizza SA, Badley AD, Prieto M, Taler SJ, Chong PP, Cummins NW. Transient Loss of HIV-1 DNA in an HIV-1 Positive Patient After Kidney Transplantation: A Case Report. Am J Med 2018 Oct; 131 (10):e423-e424 Epub 2018 May 03
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  16. Arenas-Pinto A, Grund B, Sharma S, Martinez E, Cummins N, Fox J, Klingman KL, Sedlacek D, Collins S, Flynn PM, Chasanov WM, Kedem E, Katlama C, Sierra-Madero J, Afonso C, Brouwers P, Cooper DA, INSIGHT START study group. Risk of Suicidal Behavior With Use of Efavirenz: Results from the Strategic Timing of Antiretroviral Treatment Trial. Clin Infect Dis. 2018 Jul 18; 67 (3):420-429
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  17. Natesampillai S, Cummins NW, Nie Z, Sampath R, Baker JV, Henry K, Pinzone M, O'Doherty U, Polley EC, Bren GD, Katzmann DJ, Badley AD. HIV Protease-Generated Casp8p41, When Bound and Inactivated by Bcl2, Is Degraded by the Proteasome. J Virol. 2018 Jul 1; 92 (13) Epub 2018 June 13
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  18. Sharma A, Mukewar S, Mara KC, Dierkhising RA, Kamath PS, Cummins N. Epidemiologic Factors, Clinical Presentation, Causes, and Outcomes of Liver Abscess: A 35-Year Olmsted County Study. Mayo Clin Proc Innov Qual Outcomes. 2018 Mar; 2 (1):16-25 Epub 2018 Feb 22
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  19. Nie Z, Aboulnasr F, Natesampillai S, Burke SP, Krogman A, Bren GD, Chung TDY, Anderson JR, Smart MK, Katzmann DJ, Rajagopalan G, Cummins NW, Badley AD. Both HIV-Infected and Uninfected Cells Express TRAILshort, Which Confers TRAIL Resistance upon Bystander Cells within the Microenvironment. J Immunol. 2018 Feb 1; 200 (3):1110-1123 Epub 2017 Dec 20
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  20. Lavender KJ, Pace C, Sutter K, Messer RJ, Pouncey DL, Cummins NW, Natesampillai S, Zheng J, Goldsmith J, Widera M, Van Dis ES, Phillips K, Race B, Dittmer U, Kukolj G, Hasenkrug KJ. An advanced BLT-humanized mouse model for extended HIV-1 cure studies. AIDS. 2018 Jan 2; 32 (1):1-10
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  21. Cummins NW, Rizza S, Litzow MR, Hua S, Lee GQ, Einkauf K, Chun TW, Rhame F, Baker JV, Busch MP, Chomont N, Dean PG, Fromentin R, Haase AT, Hampton D, Keating SM, Lada SM, Lee TH, Natesampillai S, Richman DD, Schacker TW, Wietgrefe S, Yu XG, Yao JD, Zeuli J, Lichterfeld M, Badley AD. Extensive virologic and immunologic characterization in an HIV-infected individual following allogeneic stem cell transplant and analytic cessation of antiretroviral therapy: A case study. PLoS Med. 2017 Nov; 14 (11):e1002461 Epub 2017 Nov 28
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  22. Ramanan P, Cummins NW, Wilhelm MP, Heimbach JK, Dierkhising R, Kremers WK, Rosen CB, Gores GJ, Razonable RR. Epidemiology, risk factors, and outcomes of infections in patients undergoing liver transplantation for hilar cholangiocarcinoma. Clin Transplant. 2017 Aug; 31 (8) Epub 2017 July 05
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  23. Cummins NW, Sainski-Nguyen AM, Natesampillai S, Aboulnasr F, Kaufmann S, Badley AD. Maintenance of the HIV Reservoir Is Antagonized by Selective BCL2 Inhibition. J Virol. 2017 Jun 1; 91 (11) Epub 2017 May 12
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  24. Jin JJ, Keith PJ, Cummins NW, Kane SV, Pritt BS, Sanchez JL. Lysinibacillus massiliensis Panniculitis Masquerading as Erythema Nodosum: A Case Report. Open Forum Infect Dis. 2017 Spring; 4 (2):ofx072 Epub 2017 Apr 06
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  25. Sampath R, Cummins NW, Natesampillai S, Bren GD, Chung TD, Baker J, Henry K, Pagliuzza A, Badley AD. Increasing procaspase 8 expression using repurposed drugs to induce HIV infected cell death in ex vivo patient cells. PLoS One. 2017; 12 (6):e0179327 Epub 2017 June 19
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  26. Cummins NW, Badley AD, Kasten MJ, Sampath R, Temesgen Z, Whitaker JA, Wilson JW, Yao JD, Zeuli J, Rizza SA. Twenty years of human immunodeficiency virus care at the Mayo Clinic: Past, present and future. World J Virol. 2016 May 12; 5 (2):63-7
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  27. Cummins NW, Sainski AM, Dai H, Natesampillai S, Pang YP, Bren GD, de Araujo Correia MCM, Sampath R, Rizza SA, O'Brien D, Yao JD, Kaufmann SH, Badley AD. Prime, Shock, and Kill: Priming CD4 T Cells from HIV Patients with a BCL-2 Antagonist before HIV Reactivation Reduces HIV Reservoir Size. J Virol. 2016 Apr; 90 (8):4032-4048 Epub 2016 Mar 28
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  28. Rizza SA, Cummins N, Hoffman-Therry M, Temesgen Z. 23rd conference on retroviruses and opportunistic infections (CROI 2016) Boston, Massachusetts, USA - February 22-25, 2016 Drugs Of The Future. 2016 Mar; 41: (3)203-12.
  29. Marcelin JR, Berg ML, Tan EM, Amer H, Cummins NW, Rizza SA. Is Abnormal Urine Protein/Osmolality Ratio Associated with Abnormal Renal Function in Patients Receiving Tenofovir Disoproxil Fumarate? PLoS One. 2016; 11 (2):e0149562 Epub 2016 Feb 12
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  30. Sampath R, Cummins NW, Badley AD. Casp8p41: The Protean Mediator of Death in CD4 T-cells that Replicate HIV. J Cell Death. 2016; 9:9-17 Epub 2016 Sept 27
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  31. Cummins NW, Neuhaus J, Chu H, Neaton J, Wyen C, Rockstroh JK, Skiest DJ, Boyd MA, Khoo S, Rotger M, Telenti A, Weinshilboum R, Badley AD, INSIGHT Study Group. Investigation of Efavirenz Discontinuation in Multi-ethnic Populations of HIV-positive Individuals by Genetic Analysis. EBioMedicine. 2015 Jul; 2 (7):706-12 Epub 2015 May 12
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  32. Cummins NW, Badley AD. Can HIV Be Cured and Should We Try? Mayo Clin Proc. 2015 Jun; 90 (6):705-9 Epub 2015 May 02
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  33. Tan EM, Marcelin JR, Tande AJ, Rizza SA, Cummins NW. Fever and Cardiac Arrest in a Patient With a Left Ventricular Assist Device. Open Forum Infect Dis. 2015 Apr; 2 (2):ofv033 Epub 2015 Mar 05
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  34. Abidi MZ, Sohail MR, Cummins N, Wilhelm M, Wengenack N, Brumble L, Shah H, Jane Hata D, McCullough A, Wendel A, Vikram HR, Kusne S, Litzow M, Letendre L, Lahr BD, Poeschla E, Walker RC. Stability in the cumulative incidence, severity and mortality of 101 cases of invasive mucormycosis in high-risk patients from 1995 to 2011: a comparison of eras immediately before and after the availability of voriconazole and echinocandin-amphotericin combination therapies. Mycoses. 2014 Nov; 57 (11):687-98 Epub 2014 July 18
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  35. Sainski AM, Dai H, Natesampillai S, Pang YP, Bren GD, Cummins NW, Correia C, Meng XW, Tarara JE, Ramirez-Alvarado M, Katzmann DJ, Ochsenbauer C, Kappes JC, Kaufmann SH, Badley AD. Casp8p41 generated by HIV protease kills CD4 T cells through direct Bak activation. J Cell Biol. 2014 Sep 29; 206 (7):867-76 Epub 2014 Sept 22
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  36. Cummins NW, Neuhaus J, Sainski AM, Strausbauch MA, Wettstein PJ, Lewin SR, Plana M, Rizza SA, Temesgen Z, Touloumi G, Freiberg M, Neaton J, Badley AD, INSIGHT SMART Study Group. Short communication: CD4 T cell declines occurring during suppressive antiretroviral therapy reflect continued production of Casp8p41. AIDS Res Hum Retroviruses. 2014 May; 30 (5):476-9 Epub 2014 Feb 14
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  37. Abidi MZ, Coelho-Prabhu N, Hargreaves J, Weiland T, Van Dyken I, Tande A, Tosh PK, Walker RC, Cummins NW. Mucormycosis in patients with inflammatory bowel disease: case series and review of the literature. Case Rep Med. 2014; 2014:637492 Epub 2014 Apr 27
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  38. Cummins NW, Sainski AM, Natesampillai S, Bren GD, Badley AD. Choice of antiretroviral therapy differentially impacts survival of HIV-infected CD4 T cells. Mol Cell Ther. 2014; 2:1 Epub 2014 Jan 03
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  39. Cummins NW, Badley AD. Making sense of how HIV kills infected CD4 T cells: implications for HIV cure. Mol Cell Ther. 2014; 2:20 Epub 2014 July 03
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  40. Cummins NW, Badley AD. Anti-apoptotic mechanisms of HIV: lessons and novel approaches to curing HIV. Cell Mol Life Sci. 2013 Sep; 70 (18):3355-63 Epub 2012 Dec 30
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  41. Baker JV, Brummel-Ziedins K, Neuhaus J, Duprez D, Cummins N, Dalmau D, DeHovitz J, Lehmann C, Sullivan A, Woolley I, Kuller L, Neaton JD, Tracy RP, INSIGHT SMART Study Team. HIV Replication Alters the Composition of Extrinsic Pathway Coagulation Factors and Increases Thrombin Generation. J Am Heart Assoc. 2013 Aug; 2(4):e000264. Epub 2013 Jul 29.
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  42. Rizza SA, Cummins N, El Atrouni W, Badley AD, Dababneh A, Temesgen Z. Advances in the treatment of HIV and chronic hepatitis C virus infection: A report from the 20th conference on retroviruses and opportunistic infections (CROI 2013). Drugs Future. 2013; 38(5):325-33.
  43. Davey RT Jr, Lynfield R, Dwyer DE, Losso MH, Cozzi-Lepri A, Wentworth D, Lane HC, Dewar R, Rupert A, Metcalf JA, Pett SL, Uyeki TM, Bruguera JM, Angus B, Cummins N, Lundgren J, Neaton JD. The association between serum biomarkers and disease outcome in influenza A(H1N1)pdm09 virus infection: results of two international observational cohort studies. PLoS One. 2013; 8(2):e57121. Epub 2013 Feb 27
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  44. Cummins NW, Weaver EA, May SM, Croatt AJ, Foreman O, Kennedy RB, Poland GA, Barry MA, Nath KA, Badley AD. Heme oxygenase-1 regulates the immune response to influenza virus infection and vaccination in aged mice. FASEB J. 2012 Jul; 26 (7):2911-8 Epub 2012 Apr 06
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  45. Elias RM, Khoo SY, Pupaibool J, Nienaber JH, Cummins NW. Multiple Pyogenic Liver Abscesses Caused by Eggerthella lenta Treated with Ertapenem: A Case Report. Case Rep Med. 2012; 2012:718130 Epub 2012 Mar 05
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  46. Schnepple DJ, Shepard B, Bren GD, Cummins NW, Natesampillai S, Trushin S, Algeciras-Schimnich A, Meng XW, Sainski AM, Rizza SA, Kaufmann SH, Badley AD. Isolation of a TRAIL antagonist from the serum of HIV-infected patients. J Biol Chem. 2011 Oct 14; 286 (41):35742-35754 Epub 2011 Aug 22
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  47. Sainski AM, Natesampillai S, Cummins NW, Bren GD, Taylor J, Saenz DT, Poeschla EM, Badley AD. The HIV-1-specific protein Casp8p41 induces death of infected cells through Bax/Bak. J Virol. 2011 Aug; 85 (16):7965-75 Epub 2011 June 08
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  48. Cummins NW, Klicpera A, Sainski AM, Bren GD, Khosla S, Westendorf JJ, Badley AD. Human immunodeficiency virus envelope protein Gp120 induces proliferation but not apoptosis in osteoblasts at physiologic concentrations. PLoS One. 2011; 6 (9):e24876 Epub 2011 Sept 12
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  49. Natesampillai S, Nie Z, Cummins NW, Jochmans D, Bren GD, Angel JB, Badley AD. Patients with discordant responses to antiretroviral therapy have impaired killing of HIV-infected T cells. PLoS Pathog. 2010 Nov 24; 6 (11):e1001213
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  50. Rizza SA, Cummins NW, Rider DN, Saeed S, Klein MB, Badley AD. Polymorphism in tumor necrosis factor-related apoptosis-inducing ligand receptor 1 is associated with poor viral response to interferon-based hepatitis C virus therapy in HIV/hepatitis C virus-coinfected individuals. AIDS. 2010 Nov 13; 24 (17):2639-44
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  51. Cummins NW, Badley AD. Mechanisms of HIV-associated lymphocyte apoptosis: 2010. Cell Death Dis. 2010 Nov 11; 1:e99
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  52. Cummins NW, Jiang W, McGinty J, Bren GD, Bosch RJ, Landay A, Deeks SG, Martin JN, Douek D, Lederman MM, Brenchley J, Badley AD. Intracellular Casp8p41 content is inversely associated with CD4 T cell count. J Infect Dis. 2010 Aug 15; 202 (3):386-91
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  53. Taylor JA, Cummins NW, Bren GD, Rizza SA, Kolbert CP, Behrens MD, Knutson KL, Kahl JC, Asmann YW, Badley AD. Casp8p41 expression in primary T cells induces a proinflammatory response. AIDS. 2010 Jun 1; 24(9):1251-8.
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  54. Cummins N, Badley A. The TRAIL to viral pathogenesis: the good, the bad and the ugly. Curr Mol Med. 2009 May; 9 (4):495-505
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  55. Cummins NW, Deziel PJ, Abraham RS, Razonable RR. Deficiency of cytomegalovirus (CMV)-specific CD8+ T cells in patients presenting with late-onset CMV disease several years after transplantation. Transpl Infect Dis. 2009 Feb; 11(1):20-7. Epub 2008 Sep 21.
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  56. Bren GD, Whitman J, Cummins N, Shepard B, Rizza SA, Trushin SA, Badley AD. Infected cell killing by HIV-1 protease promotes NF-kappaB dependent HIV-1 replication. PLoS One. 2008 May 7; 3 (5):e2112 Epub 2008 May 07
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