Publications

  1. Lee HE, Zhang L. Immunoglobulin G4-related hepatobiliary disease. Semin Diagn Pathol. 2019 Jul 24 Epub 2019 July 24
    View PubMed
  2. Nasir A, Lehrke HD, Mounajjed T, Said S, Zhang L, Yasir S, Shah SS, Chandan VS, Smyrk TC, Moreira RK, Boland Froemming JM, Herrera Hernandez LP, Wu TT, Graham RP. Albumin In Situ Hybridization Can Be Positive in Adenocarcinomas and Other Tumors From Diverse Sites. Am J Clin Pathol. 2019 Jul 5; 152 (2):190-199
    View PubMed
  3. Zhan X, Wan J, Zhang G, Song L, Gui F, Zhang Y, Li Y, Guo J, Dawra RK, Saluja AK, Haddock AN, Zhang L, Bi Y, Ji B. Elevated intracellular trypsin exacerbates acute pancreatitis and chronic pancreatitis in mice. Am J Physiol Gastrointest Liver Physiol. 2019 Jun 1; 316 (6):G816-G825 Epub 2019 Apr 03
    View PubMed
  4. Mensah ET, Smyrk T, Zhang L, Bick B, Wood-Wentz CM, Buttar N, Chari ST, Gleeson FC, Kendrick M, Levy M, Pearson R, Petersen BT, Vege S, Enders F, Limburg P, Topazian M. Cyclooxygenase-2 and Cytosolic Phospholipase A2 Are Overexpressed in Mucinous Pancreatic Cysts. Clin Transl Gastroenterol. 2019 Apr; 10 (4):e00028
    View PubMed
  5. Majumder S, Philip NA, Singh Nagpal SJ, Takahashi N, Mara KC, Kendrick ML, Smyrk TC, Zhang L, Levy MJ, Gleeson FC, Petersen BT, Pearson RK, Topazian MD, Vege SS, Chari ST. High-Grade Dysplasia in Resected Main-Duct Intraductal Papillary Mucinous Neoplasm (MD-IPMN) is Associated with an Increased Risk of Subsequent Pancreatic Cancer. Am J Gastroenterol. 2019 Mar; 114 (3):524-529
    View PubMed
  6. Liu R, Wang M, Zhang L, Zhou W, Huang Y, Guo H, Gu Y, Chen Y, Li Y, Chen C, Wang Y, Rong L, Li J, Xu J, Cao Q, Jiang Z. The clinicopathologic features of chronic active Epstein-Barr virus infective enteritis. Mod Pathol. 2019 Mar; 32 (3):387-395 Epub 2018 Oct 08
    View PubMed
  7. Qiang L, Cao H, Chen J, Weller SG, Krueger EW, Zhang L, Razidlo GL, McNiven MA. Pancreatic tumor cell metastasis is restricted by MT1-MMP binding protein MTCBP-1. J Cell Biol. 2019 Jan 7; 218 (1):317-332 Epub 2018 Nov 28
    View PubMed
  8. La Rosa S, Bernasconi B, Vanoli A, Sciarra A, Notohara K, Albarello L, Casnedi S, Billo P, Zhang L, Tibiletti MG, Sessa F. c-MYC amplification and c-myc protein expression in pancreatic acinar cell carcinomas. New insights into the molecular signature of these rare cancers. Virchows Arch. 2018 Oct; 473 (4):435-441 Epub 2018 May 02
    View PubMed
  9. Gleeson FC, Levy MJ, Roden AC, Boardman LA, Sinicrope FA, McWilliams RR, Zhang L. EUS fine-needle pancreatic core biopsy can determine eligibility for tumor-agnostic immunotherapy. Endosc Int Open. 2018 Oct; 6 (10):E1278-E1282 Epub 2018 Oct 08
    View PubMed
  10. Gleeson FC, Zhang L, Roden AC, Levy MJ. Endoscopic Ultrasound-Guided Fine-Needle Biopsies From Pancreatic Ductal Adenocarcinomas Can Be Used to Quantify PD-L1. Clin Gastroenterol Hepatol. 2018 Sep; 16 (9):1535-1536 Epub 2018 Jan 03
    View PubMed
  11. Zhang H, Jenkins SM, Lee CT, Harrington SM, Liu Z, Dong H, Zhang L. Bim is an independent prognostic marker in intrahepatic cholangiocarcinoma. Hum Pathol. 2018 Aug; 78:97-105 Epub 2018 Apr 23
    View PubMed
  12. Lee HE, Smyrk TC, Zhang L. Histologic and immunohistochemical differences between hereditary and sporadic diffuse gastric carcinoma. Hum Pathol. 2018 Apr; 74:64-72 Epub 2018 Jan 04
    View PubMed
  13. Sun Y, Lohse C, Smyrk T, Hobday T, Kroneman T, Zhang L. The Influence of Tumor Stage on the Prognostic Value of Ki-67 Index and Mitotic Count in Small Intestinal Neuroendocrine Tumors. Am J Surg Pathol. 2018 Feb; 42 (2):247-255
    View PubMed
  14. Lehrke HD, Graham RP, McWilliams RR, Lam-Himlin DM, Smyrk TC, Jenkins S, Dong H, Zhang L. Undifferentiated Pancreatic Carcinomas Display Enrichment for Frequency and Extent of PD-L1 Expression by Tumor Cells. Am J Clin Pathol. 2017 Nov 2; 148 (5):441-449
    View PubMed
  15. Graham RP, Nair AA, Davila JI, Jin L, Jen J, Sukov WR, Wu TT, Appelman HD, Torres-Mora J, Perry KD, Zhang L, Kloft-Nelson SM, Knudson RA, Greipp PT, Folpe AL. Gastroblastoma harbors a recurrent somatic MALAT1-GLI1 fusion gene. Mod Pathol. 2017 Oct; 30 (10):1443-1452 Epub 2017 July 21
    View PubMed
  16. Jin X, Pan Y, Wang L, Ma T, Zhang L, Tang AH, Billadeau DD, Wu H, Huang H. Fructose-1,6-bisphosphatase Inhibits ERK Activation and Bypasses Gemcitabine Resistance in Pancreatic Cancer by Blocking IQGAP1-MAPK Interaction. Cancer Res. 2017 Aug 15; 77 (16):4328-4341 Epub 2017 July 18
    View PubMed
  17. Liou GY, Bastea L, Fleming A, Doppler H, Edenfield BH, Dawson DW, Zhang L, Bardeesy N, Storz P. The Presence of Interleukin-13 at Pancreatic ADM/PanIN Lesions Alters Macrophage Populations and Mediates Pancreatic Tumorigenesis. Cell Rep. 2017 May 16; 19 (7):1322-1333
    View PubMed
  18. Luo K, Li Y, Yin Y, Li L, Wu C, Chen Y, Nowsheen S, Hu Q, Zhang L, Lou Z, Yuan J. USP49 negatively regulates tumorigenesis and chemoresistance through FKBP51-AKT signaling. EMBO J. 2017 May 15; 36 (10):1434-1446 Epub 2017 Mar 31
    View PubMed
  19. Dickinson KJ, Wang K, Zhang L, Allen MS, Cassivi SD, Nichols FC 3rd, Shen R, Wigle DA, Blackmon SH. Esophagectomy Outcomes in the Endoscopic Mucosal Resection Era. Ann Thorac Surg. 2017 Mar; 103: (3)890-897.
    View PubMed
  20. Liu T, Yu J, Deng M, Yin Y, Zhang H, Luo K, Qin B, Li Y, Wu C, Ren T, Han Y, Yin P, Kim J, Lee S, Lin J, Zhang L, Zhang J, Nowsheen S, Wang L, Boughey J, Goetz MP, Yuan J, Lou Z. CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1. Nat Commun. 2017 Jan 9; 8:13923 Epub 2017 Jan 09
    View PubMed
  21. Hart PA, Levy MJ, Smyrk TC, Takahashi N, Abu Dayyeh BK, Clain JE, Gleeson FC, Pearson RK, Petersen BT, Topazian MD, Vege SS, Zhang L, Chari ST. Clinical profiles and outcomes in idiopathic duct-centric chronic pancreatitis (type 2 autoimmune pancreatitis): the Mayo Clinic experience. Gut. 2016 Oct; 65 (10):1702-9 Epub 2015 June 17
    View PubMed
  22. Mohapatra S, Majumder S, Smyrk TC, Zhang L, Matveyenko A, Kudva YC, Chari ST. Diabetes Mellitus Is Associated With an Exocrine Pancreatopathy: Conclusions From a Review of Literature. Pancreas. 2016 Sep; 45 (8):1104-10
    View PubMed
  23. Said SM, Murphree MI, Mounajjed T, El-Youssef M, Zhang L. A novel GBE1 gene variant in a child with glycogen storage disease type IV. Hum Pathol. 2016 Aug; 54:152-6 Epub 2016 Apr 20
    View PubMed
  24. Wu G, Wang S, Cheng M, Peng B, Liang J, Huang H, Jiang X, Zhang L, Yang B, Cha Y, Jiang H, Huang C. The serum matrix metalloproteinase-9 level is an independent predictor of recurrence after ablation of persistent atrial fibrillation. Clinics (Sao Paulo). 2016 May; 71 (5):251-6
    View PubMed
  25. Liou GY, Doppler H, DelGiorno KE, Zhang L, Leitges M, Crawford HC, Murphy MP, Storz P. Mutant KRas-Induced Mitochondrial Oxidative Stress in Acinar Cells Upregulates EGFR Signaling to Drive Formation of Pancreatic Precancerous Lesions. Cell Rep. 2016 Mar 15; 14 (10):2325-36 Epub 2016 Mar 03
    View PubMed
  26. Baumgart S, Chen NM, Zhang JS, Billadeau DD, Gaisina IN, Kozikowski AP, Singh SK, Fink D, Strobel P, Klindt C, Zhang L, Bamlet WR, Koenig A, Hessmann E, Gress TM, Ellenrieder V, Neesse A. GSK-3beta Governs Inflammation-Induced NFATc2 Signaling Hubs to Promote Pancreatic Cancer Progression. Mol Cancer Ther. 2016 Mar; 15 (3):491-502 Epub 2016 Jan 28
    View PubMed
  27. La Rosa S, Bernasconi B, Frattini M, Tibiletti MG, Molinari F, Furlan D, Sahnane N, Vanoli A, Albarello L, Zhang L, Notohara K, Casnedi S, Chenard MP, Adsay V, Asioli S, Capella C, Sessa F. TP53 alterations in pancreatic acinar cell carcinoma: new insights into the molecular pathology of this rare cancer. Virchows Arch. 2016 Mar; 468 (3):289-96 Epub 2015 Nov 19
    View PubMed
  28. Boys JA, Worrell SG, Chandrasoma P, Vallone JG, Maru DM, Zhang L, Blackmon SH, Dickinson KJ, Dunst CM, Hofstetter WL, Lada MJ, Louie BE, Molena D, Watson TJ, DeMeester SR. Can the Risk of Lymph Node Metastases Be Gauged in Endoscopically Resected Submucosal Esophageal Adenocarcinomas? A Multi-Center Study. J Gastrointest Surg. 2016 Jan; 20 (1):6-12; discussion 12 Epub 2015 Sept 25
    View PubMed
  29. Cheng M, Wu G, Song Y, Wang L, Tu L, Zhang L, Zhang C. Celastrol-Induced Suppression of the MiR-21/ERK Signalling Pathway Attenuates Cardiac Fibrosis and Dysfunction. Cell Physiol Biochem. 2016; 38: (5)1928-38.
    View PubMed
  30. Kroneman TN, Voss JS, Lohse CM, Wu TT, Smyrk TC, Zhang L. Comparison of Three Ki-67 Index Quantification Methods and Clinical Significance in Pancreatic Neuroendocrine Tumors. Endocr Pathol. 2015 Sep; 26 (3):255-62
    View PubMed
  31. Bick BL, Enders FT, Levy MJ, Zhang L, Henry MR, Abu Dayyeh BK, Chari ST, Clain JE, Farnell MB, Gleeson FC, Kendrick ML, Pearson RK, Petersen BT, Rajan E, Vege SS, Topazian M. The string sign for diagnosis of mucinous pancreatic cysts. Endoscopy. 2015 Jul; 47: (7)626-31.
    View PubMed
  32. Liou GY, Doppler H, Necela B, Edenfield B, Zhang L, Dawson DW, Storz P. Mutant KRAS-induced expression of ICAM-1 in pancreatic acinar cells causes attraction of macrophages to expedite the formation of precancerous lesions. Cancer Discov. 2015 Jan; 5 (1):52-63 Epub 2014 Oct 31
    View PubMed
  33. Huang R, Gionfriddo MR, Zhang L, Leppin AL, Ting HH, Montori VM. Shared decision-making in the People's Republic of China: current status and future directions. Patient Prefer Adherence. 2015; 9:1129-41 Epub 2015 Aug 06
    View PubMed
  34. Hoskins JW, Jia J, Flandez M, Parikh H, Xiao W, Collins I, Emmanuel MA, Ibrahim A, Powell J, Zhang L, Malats N, Bamlet WR, Petersen GM, Real FX, Amundadottir LT. Transcriptome analysis of pancreatic cancer reveals a tumor suppressor function for HNF1A. Carcinogenesis. 2014 Dec; 35 (12):2670-8 Epub 2014 Sept 18
    View PubMed
  35. Lee CT, Wu TT, Lohse CM, Zhang L. High-mobility group AT-hook 2: an independent marker of poor prognosis in intrahepatic cholangiocarcinoma. Hum Pathol. 2014 Nov; 45(11):2334-40. Epub 2014 Aug 23
    View PubMed
  36. Mehner C, Miller E, Khauv D, Nassar A, Oberg AL, Bamlet WR, Zhang L, Waldmann J, Radisky ES, Crawford HC, Radisky DC. Tumor cell-derived MMP3 orchestrates Rac1b and tissue alterations that promote pancreatic adenocarcinoma. Mol Cancer Res. 2014 Oct; 12 (10):1430-9 Epub 2014 May 21
    View PubMed
  37. Graham RP, Barr Fritcher EG, Pestova E, Schulz J, Sitailo LA, Vasmatzis G, Murphy SJ, McWilliams RR, Hart SN, Halling KC, Roberts LR, Gores GJ, Couch FJ, Zhang L, Borad MJ, Kipp BR. Fibroblast growth factor receptor 2 translocations in intrahepatic cholangiocarcinoma. Hum Pathol. 2014 Aug; 45(8):1630-8. Epub 2014 Apr 13.
    View PubMed
  38. Graham RP, Smyrk TC, Chari ST, Takahashi N, Zhang L. Isolated IgG4-related sclerosing cholangitis: a report of 9 cases. Hum Pathol. 2014 Aug; 45(8):1722-9. Epub 2014 Apr 24.
    View PubMed
  39. Mills LD, Zhang L, Marler R, Svingen P, Fernandez-Barrena MG, Dave M, Bamlet W, McWilliams RR, Petersen GM, Faubion W, Fernandez-Zapico ME. Inactivation of the transcription factor GLI1 accelerates pancreatic cancer progression. J Biol Chem. 2014 Jun 6; 289 (23):16516-25 Epub 2014 Apr 15
    View PubMed
  40. Jia J, Bosley AD, Thompson A, Hoskins JW, Cheuk A, Collins I, Parikh H, Xiao Z, Ylaya K, Dzyadyk M, Cozen W, Hernandez BY, Lynch CF, Loncarek J, Altekruse SF, Zhang L, Westlake CJ, Factor VM, Thorgeirsson S, Bamlet WR, Hewitt SM, Petersen GM, Andresson T, Amundadottir LT. CLPTM1L promotes growth and enhances aneuploidy in pancreatic cancer cells. Cancer Res. 2014 May 15; 74 (10):2785-95 Epub 2014 Mar 19
    View PubMed
  41. Basturk O, Tang L, Hruban RH, Adsay V, Yang Z, Krasinskas AM, Vakiani E, La Rosa S, Jang KT, Frankel WL, Liu X, Zhang L, Giordano TJ, Bellizzi AM, Chen JH, Shi C, Allen P, Reidy DL, Wolfgang CL, Saka B, Rezaee N, Deshpande V, Klimstra DS. Poorly differentiated neuroendocrine carcinomas of the pancreas: a clinicopathologic analysis of 44 cases. Am J Surg Pathol. 2014 Apr; 38 (4):437-47
    View PubMed
  42. Clark CJ, Arun JS, Graham RP, Zhang L, Farnell M, Reid-Lombardo KM. Clinical characteristics and overall survival in patients with anaplastic pancreatic cancer. Am Surg. 2014 Feb; 80(2):117-23.
    View PubMed
  43. Murphy SJ, Hart SN, Lima JF, Kipp BR, Klebig M, Winters JL, Szabo C, Zhang L, Eckloff BW, Petersen GM, Scherer SE, Gibbs RA, McWilliams RR, Vasmatzis G, Couch FJ. Genetic alterations associated with progression from pancreatic intraepithelial neoplasia to invasive pancreatic tumor. Gastroenterology. 2013 Nov; 145 (5):1098-1109.e1 Epub 2013 Aug 02
    View PubMed
  44. Graham RP, Oliveira AM, Zhang L. Rare ALK expression but no ALK rearrangement in pancreatic ductal adenocarcinoma and neuroendocrine tumors. Pancreas. 2013 Aug; 42 (6):949-51
    View PubMed
  45. Banck MS, Kanwar R, Kulkarni AA, Boora GK, Metge F, Kipp BR, Zhang L, Thorland EC, Minn KT, Tentu R, Eckloff BW, Wieben ED, Wu Y, Cunningham JM, Nagorney DM, Gilbert JA, Ames MM, Beutler AS. The genomic landscape of small intestine neuroendocrine tumors. J Clin Invest. 2013 Jun; 123 (6):2502-8 Epub 2013 May 15
    View PubMed
  46. Lee CT, Zhang L, Mounajjed T, Wu TT. High mobility group AT-hook 2 is overexpressed in hepatoblastoma. Hum Pathol. 2013 May; 44(5):802-10. Epub 2012 Nov 05.
    View PubMed
  47. Fujii LL, Chari ST, El-Youssef M, Takahashi N, Topazian MD, Zhang L, Levy MJ. Pediatric pancreatic EUS-guided trucut biopsy for evaluation of autoimmune pancreatitis. Gastrointest Endosc. 2013 May; 77: (5)824-8.
    View PubMed
  48. Mills LD, Zhang Y, Marler RJ, Herreros-Villanueva M, Zhang L, Almada LL, Couch F, Wetmore C, Pasca di Magliano M, Fernandez-Zapico ME. Loss of the transcription factor GLI1 identifies a signaling network in the tumor microenvironment mediating KRAS oncogene-induced transformation. J Biol Chem. 2013 Apr 26; 288(17):11786-94. Epub 2013 Mar 12.
    View PubMed
  49. Dong M, Parsaik AK, Kremers W, Sun A, Dean P, Prieto M, Cosio FG, Gandhi MJ, Zhang L, Smyrk TC, Stegall MD, Kudva YC. Acute pancreas allograft rejection is associated with increased risk of graft failure in pancreas transplantation. Am J Transplant. 2013 Apr; 13 (4):1019-1025 Epub 2013 Feb 22
    View PubMed
  50. Mounajjed T, Zhang L, Wu TT. Glypican-3 expression in gastrointestinal and pancreatic epithelial neoplasms. Hum Pathol. 2013 Apr; 44(4):542-50. Epub 2012 Oct 15.
    View PubMed
  51. Graham RP, Shrestha B, Caron BL, Smyrk TC, Grogg KL, Lloyd RV, Zhang L. Islet-1 is a sensitive but not entirely specific marker for pancreatic neuroendocrine neoplasms and their metastases. Am J Surg Pathol. 2013 Mar; 37: (3)399-405.
    View PubMed
  52. Taner T, Atwell TD, Zhang L, Oberg TN, Harmsen WS, Slettedahl SW, Kendrick ML, Nagorney DM, Que FG. Adjunctive radiofrequency ablation of metastatic neuroendocrine cancer to the liver complements surgical resection. HPB (Oxford). 2013 Mar; 15 (3):190-5 Epub 2012 July 26
    View PubMed
  53. La Rosa S, Adsay V, Albarello L, Asioli S, Casnedi S, Franzi F, Marando A, Notohara K, Sessa F, Vanoli A, Zhang L, Capella C. Clinicopathologic study of 62 acinar cell carcinomas of the pancreas: insights into the morphology and immunophenotype and search for prognostic markers. Am J Surg Pathol. 2012 Dec; 36(12):1782-95.
    View PubMed
  54. Kipp BR, Voss JS, Kerr SE, Barr Fritcher EG, Graham RP, Zhang L, Highsmith WE, Zhang J, Roberts LR, Gores GJ, Halling KC. Isocitrate dehydrogenase 1 and 2 mutations in cholangiocarcinoma. Hum Pathol. 2012 Oct; 43(10):1552-8. Epub 2012 Apr 12.
    View PubMed
  55. Hart P, Zhang L, Sweetser S. Dysphagia in a patient with small-caliber esophagus. Gastroenterology. 2012 Oct; 143(4):e9-10. Epub 2012 Aug 23.
    View PubMed
  56. Cusati D, Zhang L, Harmsen WS, Hu A, Farnell MB, Nagorney DM, Donohue JH, Que FG, Reid-Lombardo KM, Kendrick ML. Metastatic nonfunctioning pancreatic neuroendocrine carcinoma to liver: surgical treatment and outcomes. J Am Coll Surg. 2012 Jul; 215(1):117-24; discussion 124-5.
    View PubMed
  57. Graham RP, Smyrk TC, Zhang L. Evaluation of langerhans cell infiltrate by CD1a immunostain in liver biopsy for the diagnosis of primary biliary cirrhosis. Am J Surg Pathol. 2012 May; 36(5):732-6.
    View PubMed
  58. Eppinga RD, Krueger EW, Weller SG, Zhang L, Cao H, McNiven MA. Increased expression of the large GTPase dynamin 2 potentiates metastatic migration and invasion of pancreatic ductal carcinoma. Oncogene. 2012 Mar 8; 31: (10)1228-41.
    View PubMed
  59. Zhong N, Zhang L, Takahashi N, Shalmiyev V, Canto MI, Clain JE, Deutsch JC, DeWitt J, Eloubeidi MA, Gleeson FC, Levy MJ, Mallery S, Raimondo M, Rajan E, Stevens T, Topazian M. Histologic and imaging features of mural nodules in mucinous pancreatic cysts. Clin Gastroenterol Hepatol. 2012 Feb; 10: (2)192-8, 198.e1-2.
    View PubMed
  60. Zhang L, Chari S, Smyrk TC, Deshpande V, Kloppel G, Kojima M, Liu X, Longnecker DS, Mino-Kenudson M, Notohara K, Rodriguez-Justo M, Srivastava A, Zamboni G, Zen Y. Autoimmune pancreatitis (AIP) type 1 and type 2: an international consensus study on histopathologic diagnostic criteria. Pancreas. 2011 Nov; 40(8):1172-9.
    View PubMed
  61. Wang WC, Wu TT, Chandan VS, Lohse CM, Zhang L. Ki-67 and ProExC are useful immunohistochemical markers in esophageal squamous intraepithelial neoplasia. Hum Pathol. 2011 Oct; 42(10):1430-7. Epub 2011 Mar 21.
    View PubMed
  62. Oseini AM, Chaiteerakij R, Shire AM, Ghazale A, Kaiya J, Moser CD, Aderca I, Mettler TA, Therneau TM, Zhang L, Takahashi N, Chari ST, Roberts LR. Utility of serum immunoglobulin G4 in distinguishing immunoglobulin G4-associated cholangitis from cholangiocarcinoma. Hepatology. 2011 Sep 2; 54 (3):940-8 Epub 2011 Aug 08
    View PubMed
  63. Laurini JA, Zhang L, Goldblum JR, Montgomery E, Folpe AL. Low-grade fibromyxoid sarcoma of the small intestine: report of 4 cases with molecular cytogenetic confirmation. Am J Surg Pathol. 2011 Jul; 35(7):1069-73.
    View PubMed
  64. Ibrahim SH, Zhang L, Freese DK. A 3-year-old with immunoglobulin G4-associated cholangitis. J Pediatr Gastroenterol Nutr. 2011 Jul; 53(1):109-11.
    View PubMed
  65. Raissian Y, Nasr SH, Larsen CP, Colvin RB, Smyrk TC, Takahashi N, Bhalodia A, Sohani AR, Zhang L, Chari S, Sethi S, Fidler ME, Cornell LD. Diagnosis of IgG4-related tubulointerstitial nephritis. J Am Soc Nephrol. 2011 Jul; 22 (7):1343-52 Epub 2011 June 30
    View PubMed
  66. Shimosegawa T, Chari ST, Frulloni L, Kamisawa T, Kawa S, Mino-Kenudson M, Kim MH, Kloppel G, Lerch MM, Lohr M, Notohara K, Okazaki K, Schneider A, Zhang L, International Association of Pancreatology. International consensus diagnostic criteria for autoimmune pancreatitis: guidelines of the International Association of Pancreatology. Pancreas. 2011 Apr; 40(3):352-8.
    View PubMed
  67. Rowley M, Ohashi A, Mondal G, Mills L, Yang L, Zhang L, Sundsbak R, Shapiro V, Muders MH, Smyrk T, Couch FJ. Inactivation of Brca2 promotes Trp53-associated but inhibits KrasG12D-dependent pancreatic cancer development in mice. Gastroenterology. 2011 Apr; 140 (4):1303-1313.e1-3 Epub 2011 Jan 01
    View PubMed
  68. Zhang L, Lohse CM, Dao LN, Smyrk TC. Proposed histopathologic grading system derived from a study of KIT and CK19 expression in pancreatic endocrine neoplasm. Hum Pathol. 2011 Mar; 42(3):324-31. Epub 2010 Dec 28.
    View PubMed
  69. Levy MJ, Smyrk TC, Takahashi N, Zhang L, Chari ST. Idiopathic duct-centric pancreatitis: disease description and endoscopic ultrasonography-guided trucut biopsy diagnosis. Pancreatology. 2011; 11(1):76-80. Epub 2011 Apr 27.
    View PubMed
  70. Zhang H, Jensen MH, Farnell MB, Smyrk TC, Zhang L. Primary leiomyosarcoma of the pancreas: study of 9 cases and review of literature. Am J Surg Pathol. 2010 Dec; 34(12):1849-56.
    View PubMed
  71. Sah RP, Pannala R, Zhang L, Graham RP, Sugumar A, Chari ST. Eosinophilia and allergic disorders in autoimmune pancreatitis. Am J Gastroenterol. 2010 Nov; 105(11):2485-91. Epub 2010 Jun 15.
    View PubMed
  72. Chari ST, Kloeppel G, Zhang L, Notohara K, Lerch MM, Shimosegawa T. Histopathologic and clinical subtypes of autoimmune pancreatitis: the Honolulu consensus document. Pancreas. 2010 Jul; 39(5):549-54.
    View PubMed
  73. Zhang L, Smyrk TC. Autoimmune pancreatitis and IgG4-related systemic diseases. Int J Clin Exp Pathol. 2010 May 25; 3 (5):491-504
    View PubMed
  74. Yuan J, Luo K, Zhang L, Cheville JC, Lou Z. USP10 regulates p53 localization and stability by deubiquitinating p53. Cell. 2010 Feb 5; 140 (3):384-96 Epub 2010 Jan 21
    View PubMed
  75. Fatima J, Schnelldorfer T, Barton J, Wood CM, Wiste HJ, Smyrk TC, Zhang L, Sarr MG, Nagorney DM, Farnell MB. Pancreatoduodenectomy for ductal adenocarcinoma: implications of positive margin on survival. Arch Surg. 2010 Feb; 145(2):167-72.
    View PubMed
  76. Zhang L, Smyrk TC, Young WF Jr, Stratakis CA, Carney JA. Gastric stromal tumors in Carney triad are different clinically, pathologically, and behaviorally from sporadic gastric gastrointestinal stromal tumors: findings in 104 cases. Am J Surg Pathol. 2010 Jan; 34 (1):53-64
    View PubMed
  77. Zhang L, Lewis JT, Abraham SC, Smyrk TC, Leung S, Chari ST, Poterucha JJ, Rosen CB, Lohse CM, Katzmann JA, Wu TT. IgG4+ plasma cell infiltrates in liver explants with primary sclerosing cholangitis. Am J Surg Pathol. 2010 Jan; 34(1):88-94.
    View PubMed
  78. Chari ST, Kloeppel G, Zhang L, Notohara K, Lerch MM, Shimosegawa T. Histopathologic and clinical subtypes of autoimmune pancreatitis: the honolulu consensus document. Pancreatology. 2010; 10(6):664-72. Epub 2011 Jan 18.
    View PubMed
  79. Zhang L, Smyrk TC, Oliveira AM, Lohse CM, Zhang S, Johnson MR, Lloyd RV. KIT is an independent prognostic marker for pancreatic endocrine tumors: a finding derived from analysis of islet cell differentiation markers. Am J Surg Pathol. 2009 Oct; 33: (10)1562-9.
    View PubMed
  80. Fu Z, Regan K, Zhang L, Muders MH, Thibodeau SN, French A, Wu Y, Kaufmann SH, Lingle WL, Chen J, Tindall DJ. Deficiencies in Chfr and Mlh1 synergistically enhance tumor susceptibility in mice. J Clin Invest. 2009 Sep; 119 (9):2714-24 Epub 2009 Aug 17
    View PubMed
  81. Levy MJ, Zhang L, Gleeson FC. Electronic clinical challenges and images in GI. Portal vein tumor thrombosis in a patient with previously unconfirmed hepatocellular carcinoma. Gastroenterology. 2009 May; 136(5):e1-3. Epub 2009 Mar 28.
    View PubMed
  82. Wang L, Heidt DG, Lee CJ, Yang H, Logsdon CD, Zhang L, Fearon ER, Ljungman M, Simeone DM. Oncogenic function of ATDC in pancreatic cancer through Wnt pathway activation and beta-catenin stabilization. Cancer Cell. 2009 Mar 3; 15(3):207-19.
    View PubMed
  83. Levy MJ, Gleeson FC, Zhang L. Endoscopic ultrasound fine-needle aspiration detection of extravascular migratory metastasis from a remotely located pancreatic cancer. Clin Gastroenterol Hepatol. 2009 Feb; 7(2):246-8. Epub 2008 Sep 27.
    View PubMed
  84. Gleeson FC, Zhang L, Levy MJ. Think outside the box: while investigating a patient's dyspnea, physicians made an unusual discovery. Am J Obstet Gynecol. 2009 Jan; 200: (1)114.e1-2.
    View PubMed
  85. Gleeson FC, Clayton AC, Zhang L, Clain JE, Gores GJ, Rajan E, Smyrk TC, Topazian MD, Wang KK, Wiersema MJ, Levy MJ. Adequacy of endoscopic ultrasound core needle biopsy specimen of nonmalignant hepatic parenchymal disease. Clin Gastroenterol Hepatol. 2008 Dec; 6(12):1437-40. Epub 2008 Jul 26.
    View PubMed
  86. Gleeson FC, Clain JE, Rajan E, Topazian MD, Wang KK, Wiersema MJ, Zhang L, Levy MJ. Secondary linitis plastica of the rectum: EUS features and tissue diagnosis (with video). Gastrointest Endosc. 2008 Sep; 68: (3)591-6.
    View PubMed
  87. Smoot RL, Zhang L, Sebo TJ, Que FG. Adenosquamous carcinoma of the pancreas: a single-institution experience comparing resection and palliative care. J Am Coll Surg. 2008 Sep; 207(3):368-70. Epub 2008 May 15.
    View PubMed
  88. Gleeson FC, Zhang L, Levy MJ. Primary pancreatic lymphoma: endoscopic ultrasound-guided Trucut biopsy to the rescue! Endoscopy. 2008 Sep; 40 Suppl 2:E23-4.
    View PubMed
  89. Gleeson FC, Kendrick ML, Chari ST, Zhang L, Levy MJ. Epidermoid accessory splenic cyst masquerading as a pancreatic mucinous cystic neoplasm. Endoscopy. 2008 Sep; 40 Suppl 2:E141-2. Epub 2008 Jul 16.
    View PubMed
  90. Yang H, Lee CJ, Zhang L, Sans MD, Simeone DM. Regulation of transforming growth factor beta-induced responses by protein kinase A in pancreatic acinar cells. Am J Physiol Gastrointest Liver Physiol. 2008 Jul; 295(1):G170-G178. Epub 2008 May 08.
    View PubMed
  91. Schnelldorfer T, Sarr MG, Nagorney DM, Zhang L, Smyrk TC, Qin R, Chari ST, Farnell MB. Experience with 208 resections for intraductal papillary mucinous neoplasm of the pancreas. Arch Surg. 2008 Jul; 143(7):639-46; discussion 646.
    View PubMed
  92. Ghazale A, Chari S, Zhang L, Smyrk T, Takahashi N, Levy M, Topazian M, Clain J, Pearson R, Petersen B, Swaroop Vege S, Lindor K, Farnell M. IgG4-associated cholangitis: clinical profile and response to therapy. Gastroenterology. 2008 Mar; 134(3):706-15.
  93. Ghazale A, Chari ST, Zhang L, Smyrk TC, Takahashi N, Levy MJ, Topazian MD, Clain JE, Pearson RK, Petersen BT, Vege SS, Lindor K, Farnell MB. Immunoglobulin G4-associated cholangitis: clinical profile and response to therapy. Gastroenterology. 2008 Mar; 134(3):706-15. Epub 2007 Dec 07.
    View PubMed
  94. Schnelldorfer T, Ware AL, Sarr MG, Smyrk TC, Zhang L, Qin R, Gullerud RE, Donohue JH, Nagorney DM, Farnell MB. Long-term survival after pancreatoduodenectomy for pancreatic adenocarcinoma: is cure possible? Ann Surg. 2008 Mar; 247(3):456-62.
    View PubMed
  95. Gleeson FC, de la Mora Levy JG, Zhang L, Levy MJ. The differential broadens. EUS FNA appearance and cytological findings of pancreatic angiomyolipoma. JOP. 2008 Jan 08; 9: (1)67-70.
    View PubMed
  96. Schnelldorfer T, Ware AL, Smyrk TC, Zhang L, Qin R, Gullerud RE, Sarr MG, Donohue JH, Nagorney DM, Farnell MB. Long-term survival of surgically treated pancreatic adenocarcinoma: the unique features. Annual of Surgery. 2008; 247:456.
  97. Zhang L, Visscher D, Rihal C, Aubry MC. Pulmonary veno-occlusive disease as a primary cause of pulmonary hypertension in a patient with mixed connective tissue disease. Rheumatol Int. 2007 Oct; 27 (12):1163-5 Epub 2007 May 23
    View PubMed
  98. Zhang L, Sanderson SO, Lloyd RV, Smyrk TC. Pancreatic intraepithelial neoplasia in heterotopic pancreas: evidence for the progression model of pancreatic ductal adenocarcinoma. Am J Surg Pathol. 2007 Aug; 31(8):1191-5.
    View PubMed
  99. Zhang L, Notohara K, Levy MJ, Chari ST, Smyrk TC. IgG4-positive plasma cell infiltration in the diagnosis of autoimmune pancreatitis. Mod Pathol. 2007 Jan; 20(1):23-8. Epub 2006 Sep 15.
    View PubMed
  100. Simeone DM, Zhang L, Treutelaar MK, Zhang L, Graziano K, Logsdon CD, Burant CF. Islet Hypertrophy Following Pancreatic Disruption of Smad4 Signaling. Am J Physiol Endocrinol Metab. 2006 Dec; 291(6):E1305-16 Epub 2006 May 30.
  101. Chari ST, Smyrk TC, Levy MJ, Topazian MD, Takahashi N, Zhang L, Clain JE, Pearson RK, Petersen BT, Vege SS, Farnell MB. Diagnosis of autoimmune pancreatitis: the Mayo Clinic experience. Clin Gastroenterol Hepatol. 2006 Aug; 4(8):1010-6; quiz 934. Epub 2006 Jul 14.
    View PubMed
  102. Zhang L, Chenwei L, Mahmood R, van Golen K, Greenson J, Li G, D'Silva NJ, Li X, Burant CF, Logsdon CD, Simeone DM. Identification of a putative tumor suppressor gene Rap1GAP in pancreatic cancer. Cancer Res. 2006 Jan 15; 66(2):898-906.
  103. Binkley CE, Zhang L, Greenson JK, Giordano TJ, Kuick R, Misek D, Hanash S, Logsdon CD, Simeone DM. The molecular basis of pancreatic fibrosis: common stromal gene expression in chronic pancreatitis and pancreatic adenocarcinoma. Pancreas. 2004 Nov; 29(4):254-63.
    View PubMed
  104. Zhang L, Fu Z, Binkley C, Giordano T, Burant CF, Logsdon CD, Simeone DM. Raf kinase inhibitory protein inhibits beta-cell proliferation. Surgery. 2004 Sep; 136(3):708-15.
    View PubMed
  105. Zhang L, Duan CJ, Binkley C, Li G, Uhler MD, Logsdon CD, Simeone DM. A transforming growth factor beta-induced Smad3/Smad4 complex directly activates protein kinase A. Mol Cell Biol. 2004 Mar; 24(5):2169-80.
    View PubMed
  106. Treutelaar M, Zhang L, Simeone D, Skidmore J, Hara M, Martin D, Burant C. Nestin-lineage cells contribute to microvasculature but not endocrine cells of the islets. Diabetes. 2003 Oct; 52(10):2503-12.
  107. Fu Z, Smith P, Zhang L, Rubin M, Yao Z, Keller E. Effects of Raf kinase inhibition protein expression on suppression of prostate cancer metastasis. J Natl Cancer Inst. 2003 Jun 18; 95(12):878.
  108. Simeone D, Zhang L, Graziano K, Nicke B, Pham T, Schaefer C, Logsdon C. Smad4 mediates activation of mitogen-activated protein kinases by Transforming Growth Factor beta in pancreatic acinar cells. Am J Physiol Cell. 2001 Jul; 281(1):C311-9.
  109. Zhang L, Graziano K, Pham T, Logsdon TC, Simeone D. Adenovirus-mediated gene transfer of dominant negative Smad4 blocks TGFbeta signaling in pancreatic acinar cells. Am J Physiol Gastrointest Liver Physiol. 2001 Jun; 280(6):G1247-53.
  110. Luo ZP, Zhang L, Turner RT, An KN. Effects of mechanical stress/strain and estrogen on cancellous bone structure predicted by fuzzy decision. IEEE Trans Biomed Eng. 2000 Mar; 47(3):344-51.
    View PubMed
  111. Zhang L, Feng B. Postoperative ileus. China Clin Emerg J. 1997; 2:121.
  112. Zhang L, Liu Y, Feng B. Inquiring into the mechanisms of Fuan on the dyskinesia of gastrointestinal tract in postoperative rats. China Medical Abstracts Internal Medicine. 1996; 17:181.
  113. Zhang L, Feng B. The role of nitric oxide in postoperative ileus and effect of herbs. XV World Congress of CICD International Proceedings Division, JP KIM, R.E. CONDON, MONDUZZI EDITORE. 1996:689.