Publications

  1. Ding Y, Wang M, Bu H, Li J, Lin X, Xu X. Application of an F0-based genetic assay in adult zebrafish to identify modifier genes of an inherited cardiomyopathy. Dis Model Mech. 2023 May 1; 16 (5) Epub 2022 June 23
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  2. Sabharwal A, Wishman MD, Cervera RL, Serres MR, Anderson JL, Holmberg SR, Kar B, Treichel AJ, Ichino N, Liu W, Yang J, Ding Y, Deng Y, Lacey JM, Laxen WJ, Loken PR, Oglesbee D, Farber SA, Clark KJ, Xu X, Ekker SC. Genetic therapy in a mitochondrial disease model suggests a critical role for liver dysfunction in mortality. Elife. 2022 Nov 21; 11 [Epub ahead of print]
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  3. Ellis JL, Evason KJ, Zhang C, Fourman MN, Liu J, Ninov N, Delous M, Vanhollebeke B, Fiddes I, Otis JP, Houvras Y, Farber SA, Xu X, Lin X, Stainier DYR, Yin C. A missense mutation in the proprotein convertase gene furinb causes hepatic cystogenesis during liver development in zebrafish. Hepatol Commun. 2022 Nov; 6 (11):3083-3097 Epub 2022 Aug 26
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  4. Ding Y, Lang D, Yan J, Bu H, Li H, Jiao K, Yang J, Ni H, Morotti S, Le T, Clark KJ, Port J, Ekker SC, Cao H, Zhang Y, Wang J, Grandi E, Li Z, Shi Y, Li Y, Glukhov AV, Xu X. A phenotype-based forward genetic screen identifies Dnajb6 as a sick sinus syndrome gene. Elife. 2022 Oct 18; 11
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  5. Dalland JC, Blackburn PR, Reichard KK, Johnson SH, Smadbeck JB, Vasmatzis G, Hoppman NL, Xu X, Greipp PT, Baughn LB, Peterson JF. A Novel USP25::PDGFRA Gene Fusion in a 78 Year Old Patient with a Myeloid Neoplasm. Lab Med. 2022 Sep 1; 53 (5):e134-e138
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  6. Musheer Aalam SM, Viringipurampeer IA, Walb MC, Tryggestad EJ, Emperumal CP, Song J, Xu X, Saini R, Lombaert IMA, Sarkaria JN, Garcia J, Janus JR, Kannan N. Characterization of Transgenic NSG-SGM3 Mouse Model of Precision Radiation-Induced Chronic Hyposalivation. Radiat Res. 2022 Sep 1; 198 (3):243-254
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  7. Sabharwal A, Campbell JM, Schwab TL, WareJoncas Z, Wishman MD, Ata H, Liu W, Ichino N, Hunter DE, Bergren JD, Urban MD, Urban RM, Holmberg SR, Kar B, Cook A, Ding Y, Xu X, Clark KJ, Ekker SC. A Primer Genetic Toolkit for Exploring Mitochondrial Biology and Disease Using Zebrafish. Genes (Basel). 2022 Jul 23; 13 (8) Epub 2022 July 23
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  8. Teekakirikul P, Zhu W, Xu X, Young CB, Tan T, Smith AM, Wang C, Peterson KA, Gabriel GC, Ho S, Sheng Y, Moreau de Bellaing A, Sonnenberg DA, Lin JH, Fotiou E, Tenin G, Wang MX, Wu YL, Feinstein T, Devine W, Gou H, Bais AS, Glennon BJ, Zahid M, Wong TC, Ahmad F, Rynkiewicz MJ, Lehman WJ, Keavney B, Alastalo TP, Freckmann ML, Orwig K, Murray S, Ware SM, Zhao H, Feingold B, Lo CW. Genetic resiliency associated with dominant lethal TPM1 mutation causing atrial septal defect with high heritability. Cell Rep Med. 2022 Feb 15; 3 (2):100501
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  9. Zhang W, Zhong W, Wang B, Yang J, Yang J, Yu Z, Qin Z, Shi A, Xu W, Zheng C, Schuchter LM, Karakousis GC, Mitchell TC, Amaravadi R, Herlyn M, Dong H, Gimotty PA, Daaboul G, Xu X, Guo W. ICAM-1-mediated adhesion is a prerequisite for exosome-induced T cell suppression. Dev Cell. 2022 Feb 7; 57 (3):329-343.e7 Epub 2022 Jan 31
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  10. Le T, Zhang J, Nguyen AH, Trigo Torres RS, Vo K, Dutt N, Lee J, Ding Y, Xu X, Lau MPH, Cao H. A novel wireless ECG system for prolonged monitoring of multiple zebrafish for heart disease and drug screening studies. Biosens Bioelectron. 2022 Feb 1; 197:113808 Epub 2021 Nov 16
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  11. Peng X, Lai KS, She P, Kang J, Wang T, Li G, Zhou Y, Sun J, Jin D, Xu X, Liao L, Liu J, Lee E, Poss KD, Zhong TP. Corrigendum to 'Induction of Wnt signaling antagonists and p21-activated kinase enhances cardiomyocyte proliferation during zebrafish heart regeneration'. J Mol Cell Biol. 2022 Jan 29; 13 (12):921
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  12. Baek KI, Chang SS, Chang CC, Roustaei M, Ding Y, Wang Y, Chen J, O'Donnell R, Chen H, Ashby JW, Xu X, Mack JJ, Cavallero S, Roper M, Hsiai TK. Vascular Injury in the Zebrafish Tail Modulates Blood Flow and Peak Wall Shear Stress to Restore Embryonic Circular Network. Front Cardiovasc Med. 2022; 9:841101 Epub 2022 Mar 18
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  13. Ding Y, Du K, Niu YJ, Wang Y, Xu X. Genetic Susceptibility and Mechanisms Underlying the Pathogenesis of Anthracycline-Associated Cardiotoxicity. Oxid Med Cell Longev. 2022; 2022:5818612 Epub 2022 Aug 03
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  14. Imanishi M, Cheng H, Kotla S, Deswal A, Le NT, Chini E, Ko KA, Samanthapudi VSK, Lee LL, Herrmann J, Xu X, Reyes-Gibby C, Yeung SJ, Schadler KL, Yusuf SW, Liao Z, Nurieva R, Amir ED, Burks JK, Palaskas NL, Cooke JP, Lin SH, Kobayashi M, Yoshimoto M, Abe JI. Radiation therapy induces immunosenescence mediated by p90RSK. Front Cardiovasc Med. 2022; 9:988713 Epub 2022 Nov 07
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  15. Bu H, Ding Y, Li J, Zhu P, Shih YH, Wang M, Zhang Y, Lin X, Xu X. Inhibition of mTOR or MAPK ameliorates vmhcl/myh7 cardiomyopathy in zebrafish. JCI Insight. 2021 Dec 22; 6 (24)
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  16. Qian LL, Sun X, Yang J, Wang XL, Ackerman MJ, Wang RX, Xu X, Lee HC, Lu T. Changes in ion channel expression and function associated with cardiac arrhythmogenic remodeling by Sorbs2. Biochim Biophys Acta Mol Basis Dis. 2021 Dec 1; 1867 (12):166247 Epub 2021 Sept 04
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  17. Wang Y, Lu X, Wang X, Qiu Q, Zhu P, Ma L, Ma X, Herrmann J, Lin X, Wang W, Xu X. atg7-Based Autophagy Activation Reverses Doxorubicin-Induced Cardiotoxicity. Circ Res. 2021 Oct; 129 (8):e166-e182 Epub 2021 Aug 13
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  18. Ma X, Xu X. A Swimming-based Assay to Determine the Exercise Capacity of Adult Zebrafish Cardiomyopathy Models. Bio Protoc. 2021 Aug 5; 11 (15):e4114 Epub 2021 Aug 05
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  19. Naderi AM, Bu H, Su J, Huang MH, Vo K, Trigo Torres RS, Chiao JC, Lee J, Lau MPH, Xu X, Cao H. Deep learning-based framework for cardiac function assessment in embryonic zebrafish from heart beating videos. Comput Biol Med. 2021 Aug; 135:104565 Epub 2021 June 11
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  20. Kim M, Lu L, Dvornikov AV, Ma X, Ding Y, Zhu P, Olson TM, Lin X, Xu X. TFEB Overexpression, Not mTOR Inhibition, Ameliorates RagC(S75Y) Cardiomyopathy. Int J Mol Sci. 2021 May 23; 22 (11)
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  21. Peng X, Lai KS, She P, Kang J, Wang T, Li G, Zhou Y, Sun J, Jin D, Xu X, Liao L, Liu J, Lee E, Poss KD, Zhong TP. Induction of Wnt signaling antagonists and p21-activated kinase enhances cardiomyocyte proliferation during zebrafish heart regeneration. J Mol Cell Biol. 2021 Apr 10; 13 (1):41-58
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  22. Zhu P, Qiu Q, Harris PC, Xu X, Lin X. mtor Haploinsufficiency Ameliorates Renal Cysts and Cilia Abnormality in Adult Zebrafish tmem67 Mutants. J Am Soc Nephrol. 2021 Feb 11 [Epub ahead of print]
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  23. Li LP, Zhong J, Li MH, Sun YC, Niu YJ, Wu CH, Zhou JF, Norton N, Li ZQ, Shi YY, Xu XL, Ding YH. Disruption of MAP7D1 Gene Function Increases the Risk of Doxorubicin-Induced Cardiomyopathy and Heart Failure. Biomed Res Int. 2021; 2021:8569921 Epub 2021 July 15
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  24. Zhang X, Zhang AX, Zhou B, Xu X. A feasibility study for noninvasive measurement of shear wave speed in live zebrafish. Ultrasonics. 2020 Sep; 107:106170 Epub 2020 May 11
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  25. Ding Y, Yang J, Chen P, Lu T, Jiao K, Tester DJ, Giudicessi JR, Jiang K, Ackerman MJ, Li Y, Wang DW, Lee HC, Wang DW, Xu X. Knockout of SORBS2 Protein Disrupts the Structural Integrity of Intercalated Disc and Manifests Features of Arrhythmogenic Cardiomyopathy. J Am Heart Assoc. 2020 Sep; 9 (17):e017055 Epub 2020 Aug 18
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  26. Ichino N, Serres MR, Urban RM, Urban MD, Treichel AJ, Schaefbauer KJ, Tallant LE, Varshney GK, Skuster KJ, McNulty MS, Daby CL, Wang Y, Liao HK, El-Rass S, Ding Y, Liu W, Anderson JL, Wishman MD, Sabharwal A, Schimmenti LA, Sivasubbu S, Balciunas D, Hammerschmidt M, Farber SA, Wen XY, Xu X, McGrail M, Essner JJ, Burgess SM, Clark KJ, Ekker SC. Building the vertebrate codex using the gene breaking protein trap library. Elife. 2020 Aug 11; 9
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  27. Yan J, Li H, Bu H, Jiao K, Zhang AX, Le T, Cao H, Li Y, Ding Y, Xu X. Aging-associated sinus arrest and sick sinus syndrome in adult zebrafish. PLoS One. 2020; 15 (5):e0232457 Epub 2020 May 13
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  28. Ma X, Zhu P, Ding Y, Zhang H, Qiu Q, Dvornikov AV, Wang Z, Kim M, Wang Y, Lowerison M, Yu Y, Norton N, Herrmann J, Ekker SC, Hsiai TK, Lin X, Xu X. Retinoid X receptor alpha is a spatiotemporally predominant therapeutic target for anthracycline-induced cardiotoxicity. Sci Adv. 2020 Jan; 6 (5):eaay2939 Epub 2020 Jan 29
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  29. Ding Y, Bu H, Xu X. Modeling Inherited Cardiomyopathies in Adult Zebrafish for Precision Medicine. Front Physiol. 2020; 11:599244 Epub 2020 Nov 19
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  30. Ding Y, Dvornikov AV, Ma X, Zhang H, Wang Y, Lowerison M, Packard RR, Wang L, Chen J, Zhang Y, Hsiai T, Lin X, Xu X. Haploinsufficiency of mechanistic target of rapamycin ameliorates bag3 cardiomyopathy in adult zebrafish. Dis Model Mech. 2019 Oct 1; 12 (10) Epub 2019 Oct 01
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  31. Dvornikov AV, Wang M, Yang J, Zhu P, Le T, Lin X, Cao H, Xu X. Phenotyping an adult zebrafish lamp2 cardiomyopathy model identifies mTOR inhibition as a candidate therapy. J Mol Cell Cardiol. 2019 Aug; 133:199-208 Epub 2019 June 20
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  32. Le T, Lenning M, Clark I, Bhimani I, Fortunato J, Mash P, Xu X, Cao H. Acquisition, Processing and Analysis of Electrocardiogram in Awake Zebrafish. IEEE Sens J. 2019 Jun 1; 19 (11):4283-4289 Epub 2019 Feb 06
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  33. Chen J, Ding Y, Chen M, Gau J, Jen N, Nahal C, Tu S, Chen C, Zhou S, Chang CC, Lyu J, Xu X, Hsiai TK, Packard RRS. Displacement analysis of myocardial mechanical deformation (DIAMOND) reveals segmental susceptibility to doxorubicin-induced injury and regeneration. JCI Insight. 2019 Apr 18; 4 (8)
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  34. Dvornikov AV, de Tombe PP, Xu X. Phenotyping cardiomyopathy in adult zebrafish. Prog Biophys Mol Biol. 2018 Oct; 138:116-125 Epub 2018 May 30
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  35. Zhang H, Dvornikov AV, Huttner IG, Ma X, Santiago CF, Fatkin D, Xu X. A Langendorff-like system to quantify cardiac pump function in adult zebrafish. Dis Model Mech. 2018 Sep 10; 11 (9) Epub 2018 Sept 10
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  36. Ma X, Ding Y, Wang Y, Xu X. A Doxorubicin-induced Cardiomyopathy Model in Adult Zebrafish. J Vis Exp. 2018 Jun 7; (136) Epub 2018 June 07
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  37. Lenning M, Fortunato J, Le T, Clark I, Sherpa A, Yi S, Hofsteen P, Thamilarasu G, Yang J, Xu X, Han HD, Hsiai TK, Cao H. Real-Time Monitoring and Analysis of Zebrafish Electrocardiogram with Anomaly Detection. Sensors (Basel). 2017 Dec 28; 18 (1)
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  38. Packard RRS, Baek KI, Beebe T, Jen N, Ding Y, Shi F, Fei P, Kang BJ, Chen PH, Gau J, Chen M, Tang JY, Shih YH, Ding Y, Li D, Xu X, Hsiai TK. Automated Segmentation of Light-Sheet Fluorescent Imaging to Characterize Experimental Doxorubicin-Induced Cardiac Injury and Repair. Sci Rep. 2017 Aug 17; 7 (1):8603
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  39. Long PA, Theis JL, Shih YH, Maleszewski JJ, Abell Aleff PC, Evans JM, Xu X, Olson TM. Recessive TAF1A mutations reveal ribosomopathy in siblings with end-stage pediatric dilated cardiomyopathy. Hum Mol Genet. 2017 Aug 1; 26 (15):2874-2881
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  40. Wang L, Ma X, Xu X, Zhang Y. Systematic identification and characterization of cardiac long intergenic noncoding RNAs in zebrafish. Sci Rep. 2017 Apr 28; 7 (1):1250
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  41. Fei YD, Li W, Hou JW, Guo K, Chen XM, Chen YH, Wang Q, Xu XL, Wang YP, Li YG. Oxidative Stress-Induced Afterdepolarizations and Protein Kinase C Signaling. Int J Mol Sci. 2017 Mar 30; 18 (4)
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  42. Zhu P, Sieben CJ, Xu X, Harris PC, Lin X. Autophagy activators suppress cystogenesis in an autosomal dominant polycystic kidney disease model. Hum Mol Genet. 2017 Jan 1; 26 (1):158-172
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  43. Shih YH, Dvornikov AV, Zhu P, Ma X, Kim M, Ding Y, Xu X. Exon- and contraction-dependent functions of titin in sarcomere assembly. Development. 2016 Dec 15; 143 (24):4713-4722 Epub 2016 Nov 11
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  44. Ding Y, Long PA, Bos JM, Shih YH, Ma X, Sundsbak RS, Chen J, Jiang Y, Zhao L, Hu X, Wang J, Shi Y, Ackerman MJ, Lin X, Ekker SC, Redfield MM, Olson TM, Xu X. A modifier screen identifies DNAJB6 as a cardiomyopathy susceptibility gene. JCI Insight. 2016 Sep 8; 1 (14)
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  45. Long PA, Zimmermann MT, Kim M, Evans JM, Xu X, Olson TM. De novo RRAGC mutation activates mTORC1 signaling in syndromic fetal dilated cardiomyopathy. Hum Genet. 2016 Aug; 135 (8):909-917 Epub 2016 May 27
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  46. Li X, Luo R, Fang W, Xu X, Niu G, Xu Y, Fu M, Hua W, Wu X. Effects of ventricular conduction block patterns on mortality in hospitalized patients with dilated cardiomyopathy: a single-center cohort study. BMC Cardiovasc Disord. 2016 Jun 13; 16:136 Epub 2016 June 13
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  47. Fei P, Lee J, Packard RR, Sereti KI, Xu H, Ma J, Ding Y, Kang H, Chen H, Sung K, Kulkarni R, Ardehali R, Kuo CC, Xu X, Ho CM, Hsiai TK. Cardiac Light-Sheet Fluorescent Microscopy for Multi-Scale and Rapid Imaging of Architecture and Function. Sci Rep. 2016 Mar 3; 6:22489 Epub 2016 Mar 03
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  48. Yang J, Shah S, Olson TM, Xu X. Modeling GATAD1-Associated Dilated Cardiomyopathy in Adult Zebrafish. J Cardiovasc Dev Dis. 2016 Mar; 3 (1) Epub 2016 Jan 26
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  49. Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algul H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Banhegyi G, Bao H, Barbeau B, Barrachina MD, Barreiro E, Bartel B, Bartolome A, Bassham DC, Bassi MT, Bast RC Jr, Basu A, Batista MT, Batoko H, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beaulieu JF, Beck GR Jr, Becker C, Beckham JD, Bedard PA, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, Benard G, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernard A, Bernard M, Bernassola F, Bertolotti A, Bess AS, Besteiro S, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bianchi MW, Biard-Piechaczyk M, Billes V, Bincoletto C, Bingol B, Bird SW, Bitoun M, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Bockler S, Boes M, Boesze-Battaglia K, Boise LH, Bolino A, Boman A, Bonaldo P, Bordi M, Bosch J, Botana LM, Botti J, Bou G, Bouche M, et al, Chen CJ, Chen G, Chen P, Chen Q, Chen W, Cooper JM, Dong Z, Fan C, Fernandez-Zapico ME, Fiesel FC, Gao F, Ge L, Guo C, Guo L, Harris AL, Her C, Hu D, Hu H, Hussain S, Jackson DJ, Jackson WT, Jiang H, Jiang Y, Jimenez A, Kim HY, Kim MM, Kumar D, Lee GM, Lee SJ, Lerman LO, Lewis PA, Li F, Li K, Liu F, Liu Y, Ma J, Maeda A, Martin KR, Martinez J, McCormick C, Prince S, Ryan KM, Sanchez AM, Schulze RJ, Sharma S, Sinicrope FA, Sood AK, Springer W, Stevens C, Subramaniam S, Sun Y, Tang D, Valverde AM, Venkatachalam K, Wang G, Wen X, Weyand CM, Wu GS, Xiao H, Xiao J, Xu X, Xu Z, Yang Q, Yu H, Yu L, Yu Z, Yuan J, Zhang F, Zhang Y, Zhu W. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016; 12 (1):1-222
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  50. Zhu P, Xu X, Lin X. Both ciliary and non-ciliary functions of Foxj1a confer Wnt/beta-catenin signaling in zebrafish left-right patterning. Biol Open. 2015 Oct 2; 4 (11):1376-86 Epub 2015 Oct 02
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  51. Shih YH, Zhang Y, Ding Y, Ross CA, Li H, Olson TM, Xu X. Cardiac transcriptome and dilated cardiomyopathy genes in zebrafish. Circ Cardiovasc Genet. 2015 Apr; 8 (2):261-9 Epub 2015 Jan 11
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  52. Sun Y, Fang Y, Xu X, Lu G, Chen Z. Evidence of an association between age-related functional modifications and pathophysiological changes in Zebrafish heart. Gerontology. 2015; 61(5):435-47.
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  53. Yang J, Shih YH, Xu X. Understanding cardiac sarcomere assembly with zebrafish genetics. Anat Rec (Hoboken). 2014 Sep; 297 (9):1681-93
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  54. Yang J, Hartjes KA, Nelson TJ, Xu X. Cessation of contraction induces cardiomyocyte remodeling during zebrafish cardiogenesis. Am J Physiol Heart Circ Physiol. 2014 Feb; 306 (3):H382-95 Epub 2013 Dec 06
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  55. Li X, Luo R, Gu H, Deng Y, Xu X, Wu X, Hua W. Cardiac troponin T (TNNT2) mutations in chinese dilated cardiomyopathy patients. Biomed Res Int. 2014; 2014:907360 Epub 2014 July 07
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  56. Campbell JM, Hartjes KA, Nelson TJ, Xu X, Ekker SC. New and TALENted genome engineering toolbox. Circ Res. 2013 Aug 16; 113 (5):571-87
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  57. Ding Y, Liu W, Deng Y, Jomok B, Yang J, Huang W, Clark KJ, Zhong TP, Lin X, Ekker SC, Xu X. Trapping cardiac recessive mutants via expression-based insertional mutagenesis screening. Circ Res. 2013 Feb 15; 112 (4):606-17 Epub 2013 Jan 02
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  58. Bishu K, Ogut O, Kushwaha S, Mohammed SF, Ohtani T, Xu X, Brozovich FV, Redfield MM. Anti-remodeling effects of rapamycin in experimental heart failure: dose response and interaction with angiotensin receptor blockade. PLoS One. 2013; 8 (12):e81325 Epub 2013 Dec 03
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  59. Yang J, Xu X. alpha-Actinin2 is required for the lateral alignment of Z discs and ventricular chamber enlargement during zebrafish cardiogenesis. FASEB J. 2012 Oct; 26 (10):4230-42 Epub 2012 July 05
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  60. Kushwaha S, Xu X. Target of rapamycin (TOR)-based therapy for cardiomyopathy: evidence from zebrafish and human studies. Trends Cardiovasc Med. 2012 Feb; 22 (2):39-43 Epub 2012 July 28
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  61. Caron A, Xu X, Lin X. Wnt/beta-catenin signaling directly regulates Foxj1 expression and ciliogenesis in zebrafish Kupffer's vesicle. Development. 2012 Feb; 139 (3):514-24 Epub 2011 Dec 21
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  62. Yang J, Xu X. Immunostaining of dissected zebrafish embryonic heart. J Vis Exp. 2012 Jan 10; (59):e3510
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  63. Sun X, Xu X. Anemic zebrafish models of cardiomyopathy. Methods in Pharmacology and Toxicology. 2012; 41-54.
  64. Ding Y, Sun X, Xu X. TOR-autophagy signaling in adult zebrafish models of cardiomyopathy. Autophagy. 2012 Jan; 8 (1):142-3 Epub 2012 Jan 01
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  65. Hoage T, Ding Y, Xu X. Quantifying cardiac functions in embryonic and adult zebrafish. Methods Mol Biol. 2012; 843:11-20
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  66. Hoage T, Sun X, Xu X. Functions of the Wnt/beta-catenin pathway in an anemia-induced zebrafish model of cardiomyopathy are location dependent. Biochem Biophys Res Commun. 2011 Nov 25; 415 (3):490-6 Epub 2011 Oct 28
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  67. Ding Y, Sun X, Huang W, Hoage T, Redfield M, Kushwaha S, Sivasubbu S, Lin X, Ekker S, Xu X. Haploinsufficiency of target of rapamycin attenuates cardiomyopathies in adult zebrafish. Circ Res. 2011 Sep 2; 109 (6):658-69 Epub 2011 July 14
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  68. Clark KJ, Balciunas D, Pogoda HM, Ding Y, Westcot SE, Bedell VM, Greenwood TM, Urban MD, Skuster KJ, Petzold AM, Ni J, Nielsen AL, Patowary A, Scaria V, Sivasubbu S, Xu X, Hammerschmidt M, Ekker SC. In vivo protein trapping produces a functional expression codex of the vertebrate proteome. Nat Methods. 2011 Jun; 8 (6):506-15 Epub 2011 May 08
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  69. Zhang R, Yang J, Zhu J, Xu X. Depletion of zebrafish Tcap leads to muscular dystrophy via disrupting sarcomere-membrane interaction, not sarcomere assembly. Hum Mol Genet. 2009 Nov 1; 18 (21):4130-40 Epub 2009 Aug 12
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  70. Sun X, Hoage T, Bai P, Ding Y, Chen Z, Zhang R, Huang W, Jahangir A, Paw B, Li YG, Xu X. Cardiac hypertrophy involves both myocyte hypertrophy and hyperplasia in anemic zebrafish. PLoS One. 2009 Aug 12; 4 (8):e6596
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  71. Huang W, Zhang R, Xu X. Myofibrillogenesis in the developing zebrafish heart: A functional study of tnnt2. Dev Biol. 2009 Jul 15; 331 (2):237-49 Epub 2009 May 07
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  72. Zhang R, Xu X. Transient and transgenic analysis of the zebrafish ventricular myosin heavy chain (vmhc) promoter: an inhibitory mechanism of ventricle-specific gene expression. Dev Dyn. 2009 Jun; 238 (6):1564-73
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  73. Lin X, Xu X. Distinct functions of Wnt/beta-catenin signaling in KV development and cardiac asymmetry. Development. 2009 Jan; 136 (2):207-17
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  74. Chen Z, Huang W, Dahme T, Rottbauer W, Ackerman MJ, Xu X. Depletion of zebrafish essential and regulatory myosin light chains reduces cardiac function through distinct mechanisms. Cardiovasc Res. 2008 Jul 1; 79(1):97-108. Epub 2008 Mar 14.
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  75. Xu X, Pasricha PJ, Sallam HS, Ma L, Chen JD. Clinical significance of quantitative assessment of rectoanal inhibitory reflex (RAIR) in patients with constipation. J Clin Gastroenterol. 2008 Jul; 42 (6):692-8
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  76. Sun X, Zhang R, Lin X, Xu X. Wnt3a regulates the development of cardiac neural crest cells by modulating expression of cysteine-rich intestinal protein 2 in rhombomere 6. Circ Res. 2008 Apr 11; 102(7):831-9. Epub 2008 Feb 21.
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  77. Wang L, Dutta SK, Kojima T, Xu X, Khosravi-Far R, Ekker SC, Mukhopadhyay D. Neuropilin-1 modulates p53/caspases axis to promote endothelial cell survival. PLoS One. 2007 Nov 14; 2 (11):e1161
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  78. Xu X, Pasricha PJ, Chen JD. Feasibility of gastric electrical stimulation by use of endoscopically placed electrodes. Gastrointest Endosc. 2007 Nov; 66 (5):981-6
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  79. Lin X, Rinaldo L, Fazly AF, Xu XL. Depletion of Med10 enhances Wnt and suppresses Nodal signaling during zebrafish embryogenesis. Dev Biol. 2007 Mar 15; 303(2):536-48.
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  80. Rich A, Leddon SA, Hess SL, Gibbons SJ, Miller S, Xu X, Farrugai G. Kit-like immunoreactivity in the zebrafish gastrointestinal tract reveals putative ICC. Dev Dyn. 2007 Mar; 236(3):903-11.
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  81. Seeley M, Huang W, Chen Z, Wolff WO, Lin X, Xu X. Depletion of zebrafish titin reduces cardiac contractility by disrupting the assembly of Z-discs and A-bands. Circ Res. 2007 Feb 2; 100 (2):238-45 Epub 2006 Dec 14
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  82. Wang L, Mukhopadhyay D, Xu X. C terminus of RGS-GAIP-interacting protein conveys neuropilin-1-mediated signaling during angiogenesis. FASEB J. 2006 Jul; 20(9):1513-5. Epub 2006 Jun 05.
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  83. Bos JM, Poley RN, Ny M, Tester DJ, Xu X, Vatta M, Towbin JA, Gersh BJ, Ommen SR, Ackerman MJ. Genotype-phenotype relationships involving hypertrophic cardiomyopathy-associated mutations in titin, muscle LIM protein, and telethonin. Mol Genet Metab. 2006 May; 88 (1):78-85 Epub 2005 Dec 13
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  84. Xu X, Meiler SE, Zhong TP, Mohideen M, Crossley DA, Burggren WW, Fishman MC. Cardiomyopathy in zebrafish due to mutation in an alternatively spliced exon of titin. Nat Genet. 2002 Feb; 30(2):205-9.
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  85. Zaffran S, Xu X, Lo PC, Lee HH, Frasch M. Cardiogenesis in the Drosophila model: control mechanisms during early induction and diversification of cardiac progenitors. Cold Spring Harb Symp Quant Biol. 2002; 67:1-12.
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  86. Nguyen HT, Xu X. Drosophila mef2 expression during mesoderm development is controlled by a complex array of cis-acting regulatory modules. Dev Biol. 1998 Dec 15; 204(2):550-66.
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