Publications

  1. Jamali SA, Turnbull MT, Kanekiyo T, Vishnu P, Zubair AC, Raper CC, Tawk RG, Freeman WD. Elevated Neutrophil-Lymphocyte Ratio is Predictive of Poor Outcomes Following Aneurysmal Subarachnoid Hemorrhage. J Stroke Cerebrovasc Dis. 2020 Apr; 29 (4):104631 Epub 2020 Jan 18
    View PubMed
  2. Peacock SH, Grek AA, Rogers ER, Freeman WD, White LJ, Li Z, Hartjes T, Naessens JM. Neuro R(2) score: Predicting high-risk neurologic readmissions within 30 days. Neurology. 2020 Mar 13 [Epub ahead of print]
    View PubMed
  3. Stewart MW, Hasan SA, Collins C, Stanko C, Summer J, Brazis PW, Tawk R, Freeman WD. Can Baseline Computed Tomography Scans Be Used to Identify Patients at High Risk of Vision Loss due to Terson Syndrome? Am J Ophthalmol. 2020 Mar; 211:217-228 Epub 2019 Sept 25
    View PubMed
  4. Erben Y, Li Y, Da Rocha-Franco JA, Tawk RG, Barrett KM, Freeman WD, Lin M, Miller D, Beck AW, Scali ST, Farres H, Brott TG, Meschia JF, Hakaim AG. Higher Long-Term Mortality with Carotid Artery Stenting in Asymptomatic Male Compared with Female Patients in the Southeastern Vascular Study Group. Ann Vasc Surg. 2020 Feb 3 Epub 2020 Feb 03
    View PubMed
  5. Porter AL, Ebot J, Lane K, Mooney LH, Lannen AM, Richie EM, Dlugash R, Mayo S, Brott TG, Ziai W, Freeman WD, Hanley DF. Enhancing the Informed Consent Process Using Shared Decision Making and Consent Refusal Data from the CLEAR III Trial. Neurocrit Care. 2020 Feb; 32 (1):340-347
    View PubMed
  6. Cheshire WP, Barrett KM, Eidelman BH, Mauricio EA, Huang JF, Freeman WD, Robinson MT, Salomon GR, Ball CT, Gamble DM, Melton VS, Meschia JF. Patient perception of physician empathy in stroke telemedicine. J Telemed Telecare. 2020 Jan 27; 1357633X19899237 [Epub ahead of print]
    View PubMed
  7. Peacock S, Peel JB, Farres H, Miller D, Ng L, Freeman WD. Vasovagal-Mediated Emergency From a Left Internal Carotid Aneurysm. Neurohospitalist. 2020 Jan; 10 (1):69-70 Epub 2019 Apr 07
    View PubMed
  8. Tipton PW, D'Souza CE, Greenway MRF, Peel JB, Barrett KM, Eidelman BH, Meschia JF, Mauricio EA, Hattery WM, Siegel JL, Huang JF, TerKonda SP, Demaerschalk BM, Freeman WD. Incorporation of Telestroke into Neurology Residency Training: "Time Is Brain and Education". Telemed J E Health. 2019 Dec 10 [Epub ahead of print]
    View PubMed
  9. Hasan TF, Turnbull MT, Vatz KA, Robinson MT, Mauricio EA, Freeman WD. Burnout and attrition: Expanding the gender gap in neurology? Neurology. 2019 Dec 3; 93 (23):1002-1008 Epub 2019 Nov 05
    View PubMed
  10. Borsato GS, Siegel JL, Rose MQ, Ojard M, Feyissa AM, Quinones-Hinojosa A, Jackson DA, Rogers ER, Freeman WD. Ketamine in seizure management and future pharmacogenomic considerations. Pharmacogenomics J. 2019 Nov 27 [Epub ahead of print]
    View PubMed
  11. Clifton W, Dove C, Damon A, Freeman WD, Brown B. 3-Dimensional Simulation Videography for Instructional Placement of Bedside External Ventricular Drains. World Neurosurg. 2019 Nov; 131:242 Epub 2019 July 11
    View PubMed
  12. Mauricio EA, Freeman WD. Good Night, Geese. J Gen Intern Med. 2019 Nov; 34 (11):2681
    View PubMed
  13. Zahra K, Gopal N, Freeman WD, Turnbull MT. Using Cerebral Metabolites to Guide Precision Medicine for Subarachnoid Hemorrhage: Lactate and Pyruvate. Metabolites. 2019 Oct 23; 9 (11)
    View PubMed
  14. Peacock SH, James C, Turnbull MT, Cowart JB, Reid JM, Freeman WD. Pharmacogenomics of Cytochrome P450 of Nimodipine Metabolism After Aneurysmal Subarachnoid Hemorrhage. J Neurosci Nurs. 2019 Oct; 51 (5):238-242
    View PubMed
  15. Marenco-Hillembrand L, Suarez-Meade P, Ruiz Garcia H, Murguia-Fuentes R, Middlebrooks EH, Kangas L, Freeman WD, Chaichana KL. Minimally invasive surgery and transsulcal parafascicular approach in the evacuation of intracerebral haemorrhage Stroke Vasc Neurol. 2019.
  16. Erben Y, Barrett KM, Freeman WD, Lin M, Tawk R, Ball CT, Melton VS, Thuro LM, Hakaim AG, Brott TG, Meschia JF. Prevalence of Previously Undiagnosed Abdominal Aortic Aneurysms in Patients with Intracranial Aneurysms: From the Brain and Aortic Aneurysms Study (BAAS). Neurocrit Care. 2019 Sep 25 Epub 2019 Sept 25
    View PubMed
  17. Santos CD, Matos NL, Asleh R, Dawit S, Rabinstein AA, O'Carroll CB, Li Z, Freeman WD. The Dilemma of Resuming Antithrombotic Therapy After Intracranial Hemorrhage in Patients With Left Ventricular Assist Devices. Neurocrit Care. 2019 Sep 17 Epub 2019 Sept 17
    View PubMed
  18. Soares C, Clifton W, Freeman WD. Use of Handheld Video Otoscopy for the Diagnosis of Acute Otitis Media: Technical Note. Cureus. 2019 Sep 1; 11 (9):e5547 Epub 2019 Sept 01
    View PubMed
  19. Akinduro OO, Vivas-Buitrago TG, Haranhalli N, Ganaha S, Mbabuike N, Turnbull MT, Tawk RG, Freeman WD. Predictors of Ventriculoperitoneal shunting following Subarachnoid Hemorrhage treated with External Ventricular Drainage. Neurocrit Care. 2019 Aug 13 [Epub ahead of print]
    View PubMed
  20. Ziai WC, Thompson CB, Mayo S, McBee N, Freeman WD, Dlugash R, Ullman N, Hao Y, Lane K, Awad I, Hanley DF, Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage (CLEAR III) Investigators. Intracranial Hypertension and Cerebral Perfusion Pressure Insults in Adult Hypertensive Intraventricular Hemorrhage: Occurrence and Associations With Outcome. Crit Care Med. 2019 Aug; 47 (8):1125-1134
    View PubMed
  21. Clifton WE, Damon AC, Freeman WD. Development of a Lumbar Drain Simulator for Instructional Technique and Skill Assessment. Neurocrit Care. 2019 Jul 22 Epub 2019 July 22
    View PubMed
  22. Freeman WD, Karney M. Challenges of Personal Health Records. JAMA 2019 Jun 18; 321 (23):2369
    View PubMed
  23. Blackburn PR, Lin WL, Miller DA, Lorenzo-Betancor O, Edwards ES, Zimmermann MT, Farrugia LP, Freeman WD, Soto AI, Walton RL, Klee EW, Atwal PS, Abraham RS, Billadeau DD, Ross OA, Dickson DW, Meschia JF. X-Linked Lymphoproliferative Syndrome Presenting as Adult-Onset Multi-Infarct Dementia. J Neuropathol Exp Neurol. 2019 May 1; 78 (5):460-466
    View PubMed
  24. Peacock SH, Peel JB, Farres H, Miller DA, Ng LK, Freeman WD. Vasovagal-Mediated Emergency From a Left Internal Carotid Aneurysm The Neurohospitalist. 2019.
  25. Huang P, Freeman WD, Edenfield BH, Brott TG, Meschia JF, Zubair AC. Safety and Efficacy of Intraventricular Delivery of Bone Marrow-Derived Mesenchymal Stem Cells in Hemorrhagic Stroke Model. Sci Rep. 2019 Apr 5; 9 (1):5674 Epub 2019 Apr 05
    View PubMed
  26. McLaughlin DC, Chaichana KL, Freeman WD. Angel Wing Pneumocephalus Sign Following Transsphenoidal Surgery. Neurohospitalist. 2019 Apr; 9 (2):116-117 Epub 2018 July 05
    View PubMed
  27. Freeman WD, Ziai WC, Hanley D. Ventriculostomy-Associated Infection (VAI): In Search of a Definition. Neurocrit Care 2019 Feb; 30 (1):224-225
    View PubMed
  28. Peacock S, Siegel J, Harmer E, Alejos D, Freeman WD. Evaluation of Hospital-wide Readmission Risk Calculator to Predict 30-Day Readmission in Neurocritical Care Patients. J Neurosci Nurs. 2019 Feb; 51 (1):16-19
    View PubMed
  29. Haranhalli N, Mbabuike N, Grewal SS, Hasan TF, Heckman MG, Freeman WD, Gupta V, Vibhute P, Brown BL, Miller DA, Jahromi BS, Tawk RG. Topographic correlation of infarct area on CT perfusion with functional outcome in acute ischemic stroke. J Neurosurg. 2019 Jan 11; 1-9 [Epub ahead of print]
    View PubMed
  30. Pizzi MA, Alejos D, Hasan TF, Atwal PS, Krishnaiengar SR, Freeman WD. Adult Presentation of Ornithine Transcarbamylase Deficiency: 2 Illustrative Cases of Phenotypic Variability and Literature Review. Neurohospitalist. 2019 Jan; 9 (1):30-36 Epub 2018 Mar 26
    View PubMed
  31. Turnbull MT, Zubair AC, Meschia JF, Freeman WD. Mesenchymal stem cells for hemorrhagic stroke: status of preclinical and clinical research. NPJ Regen Med. 2019; 4:10 Epub 2019 May 13
    View PubMed
  32. Ebot J, Freeman WD, Wharen R, Diaz MA, Libertin C. MRSA Spinal Epidural Abscess as a Neurosurgical and Infectious Disease Emergency with Unresolved Antimicrobial Solution. Case Rep Infect Dis. 2019; 2019:7413089 Epub 2019 Jan 30
    View PubMed
  33. Lorenzo-Betancor O, Blackburn PR, Edwards E, Vazquez-do-Campo R, Klee EW, Labbe C, Hodges K, Glover P, Sigafoos AN, Soto AI, Walton RL, Doxsey S, Bober MB, Jennings S, Clark KJ, Asmann Y, Miller D, Freeman WD, Meschia J, Ross OA. PCNT point mutations and familial intracranial aneurysms. Neurology. 2018 Dec 4; 91 (23):e2170-e2181 Epub 2018 Nov 09
    View PubMed
  34. Hasan TF, Duarte W, Akinduro OO, Goldstein ED, Hurst R, Haranhalli N, Miller DA, Wharen RE Jr, Tawk RG, Freeman WD. Nonaneurysmal "Pseudo-Subarachnoid Hemorrhage" Computed Tomography Patterns: Challenges in an Acute Decision-Making Heuristics. J Stroke Cerebrovasc Dis. 2018 Sep; 27 (9):2319-2326 Epub 2018 June 05
    View PubMed
  35. McLaughlin DC, Hartjes TM, Freeman WD. Sleep Deprivation in Neurointensive Care Unit Patients From Serial Neurological Checks: How Much Is Too Much? J Neurosci Nurs. 2018 Aug; 50 (4):205-210
    View PubMed
  36. Yoon JW, Chen RE, Kim EJ, Akinduro OO, Kerezoudis P, Han PK, Si P, Freeman WD, Diaz RJ, Komotar RJ, Pirris SM, Brown BL, Bydon M, Wang MY, Wharen RE Jr, Quinones-Hinojosa A. Augmented reality for the surgeon: Systematic review. Int J Med Robot. 2018 Aug; 14 (4):e1914 Epub 2018 Apr 30
    View PubMed
  37. Muller A, Mould WA, Freeman WD, McBee N, Lane K, Dlugash R, Thompson R, Nekoovaght-Tak S, Madan V, Ali H, Stadnik A, Awad I, Hanley D, Ziai WC, CLEAR investigators. The Incidence of Catheter Tract Hemorrhage and Catheter Placement Accuracy in the CLEAR III Trial. Neurocrit Care. 2018 Aug; 29 (1):23-32
    View PubMed
  38. Searcy S, Akinduro OO, Spector A, Yoon JW, Brown BL, Freeman WD. Heart-Shaped Bilateral Medullary Pyramidal Infarction as a Pathognomonic Finding of Anterior Spinal Artery Occlusion. Neurocrit Care. 2018 Jun; 28 (3):388-394
    View PubMed
  39. Goldstein ED, Schnusenberg L, Mooney L, Raper CC, McDaniel S, Thorpe DA, Franke MT, Anderson LK, McClure LL, Oglesby MM, Lewis CY, Velichko C, Bradley BG, Horn WW Jr, Reid AN, Siegel JL, Cannistraro R, Bechtle P, Barbosa MT, Silvers SM, Brown BL, Freeman WD, Miller DA, Barrett KM, Huang JF. Reducing Door-to-Reperfusion Time for Mechanical Thrombectomy With a Multitiered Notification System for Acute Ischemic Stroke. Mayo Clin Proc Innov Qual Outcomes. 2018 Jun; 2 (2):119-128 Epub 2018 May 24
    View PubMed
  40. McLaughlin DC, Margretta MM, Freeman WD. Aneurysmal Subarachnoid Hemorrhage Mortality After Implementation of Nocturnist Advanced Practice Provider Coverage. J Neurosci Nurs. 2018 Apr; 50 (2):102-104
    View PubMed
  41. Tallarico RT, Pizzi MA, Freeman WD. Investigational drugs for vasospasm after subarachnoid hemorrhage. Expert Opin Investig Drugs. 2018 Apr; 27 (4):313-324 Epub 2018 Apr 06
    View PubMed
  42. Lopez-Chiriboga AS, Yoon JW, Siegel JL, Harriott AM, Pirris S, Eidelman BH, Freeman WD. Granulomatous Angiitis of the Central Nervous System Associated with Hodgkin's Lymphoma: Case Report and Literature Review. J Stroke Cerebrovasc Dis. 2018 Jan; 27 (1):e5-e8 Epub 2017 Sept 21
    View PubMed
  43. Lowman p, Tomlinson A, Freeman WD. Hypothermia and Targeted Temperature Management after Cardiac Arrest Northeast Florida Medicine. 2017.
  44. Brown SM, Fifield SW, Pizzi MA, Alejos D, Richie AN, Dinh TA, Cheshire WP Jr, Meek SE, Freeman WD. A Preliminary Observational Study of Anovulatory Uterine Bleeding After Aneurysmal Subarachnoid Hemorrhage. J Neurosci Nurs. 2017 Dec; 49 (6):363-371
    View PubMed
  45. Yoon JW, Chen RE, Han PK, Si P, Freeman WD, Pirris SM. Technical feasibility and safety of an intraoperative head-up display device during spine instrumentation. Int J Med Robot. 2017 Sep; 13 (3) Epub 2016 Aug 29
    View PubMed
  46. Torbey MT, Brophy GM, Varelas PN, Bosel J, Manno E, Bader MK, Suarez JI, Seder D, Freeman WD. Guidelines for Family-Centered Care in Neuro-ICU Populations: Caveats for Routine Palliative Care. Crit Care Med 2017 Jun; 45 (6):e620-e621
    View PubMed
  47. Barrett KM, Pizzi MA, Kesari V, TerKonda SP, Mauricio EA, Silvers SM, Habash R, Brown BL, Tawk RG, Meschia JF, Wharen R, Freeman WD. Ambulance-based assessment of NIH Stroke Scale with telemedicine: A feasibility pilot study. J Telemed Telecare. 2017 May; 23 (4):476-483 Epub 2016 May 13
    View PubMed
  48. Siegel JL, Pizzi MA, Freeman WD. Stroke Diagnosis and Treatment in the Emergency Department. JAMA Neurol 2017 Mar 1; 74 (3):362
    View PubMed
  49. Lopez Chiriboga AS, Yoon J, Siegel J, Dickson D, Freeman WD, Pirris S, Harriott A. Granulomatous Angiitis of the Central Nervous System Associated with Hodgkin’s Lymphoma Journal of Clinical Neuroscience.2017;
  50. Runjaic S, Nordeen JD, Soto-Arenall MW, Johns GS, Miller D, Brown B, Freeman WD. Safety and Efficacy of Intensified Antiplatelet Therapy in Patients Undergoing Neuroendovascular Procedures. J Vasc Interv Neurol. 2017 Jan; 9 (3):51-56
    View PubMed
  51. Pizzi MA, Kamireddi P, Tatum WO, Shih JJ, Jackson DA, Freeman WD. Transition from intravenous to enteral ketamine for treatment of nonconvulsive status epilepticus. J Intensive Care. 2017; 5:54 Epub 2017 Aug 08
    View PubMed
  52. Dhakal LP, Tatum WO, Freeman WD. Train of four stimulation artifact mimicking a seizure during computerized automated ICU EEG monitoring. Epilepsy Behav Case Rep. 2017; 8:69-72 Epub 2017 Sept 11
    View PubMed
  53. Burrell C, Avalon NE, Siegel J, Pizzi M, Dutta T, Charlesworth MC, Freeman WD. Precision medicine of aneurysmal subarachnoid hemorrhage, vasospasm and delayed cerebral ischemia. Expert Rev Neurother. 2016 Nov; 16 (11):1251-1262 Epub 2016 July 11
    View PubMed
  54. Manno EM, Freeman WD, Livesay S, Geocadin RG, Torbey M, Nyquist P, Hemphill C, Neurocritical Care Society, Dr Edward Manno, Neurocritical Care Society President. Expertise Matters. Crit Care Med 2016 Nov; 44 (11):e1147-e1148
    View PubMed
  55. Dhakal LP, Harriott AM, Capobianco DJ, Freeman WD. Headache and Its Approach in Today's NeuroIntensive Care Unit. Neurocrit Care. 2016 Oct; 25 (2):320-34
    View PubMed
  56. Siegel J, Freeman WD, Broderick DF, Robles H, Thiel DD, Wszolek ZK. Ostry pooperacyjny zespól kr?gowo-podstawny – znaczenia lokalizacji klinicznej (Polish) [Postoperative acute vertebrobasilar syndrome – the importance of clinical localization]. Medycyna Praktyczna Neurologia 2016.2016;()3:61-66.
  57. Pizzi MA, Alejos DA, Siegel JL, Kim BY, Miller DA, Freeman WD. Cerebral Venous Thrombosis Associated with Intracranial Hemorrhage and Timing of Anticoagulation after Hemicraniectomy. J Stroke Cerebrovasc Dis. 2016 Sep; 25: (9)2312-6.
    View PubMed
  58. Freeman WD. Proton Pump Inhibitors and Dementia Incidence. JAMA Neurol 2016 Aug 1; 73 (8):1026-7
    View PubMed
  59. Dhakal LP, Sen A, Stanko CM, Rawal B, Heckman MG, Hoyne JB, Dimberg EL, Freeman ML, Ng LK, Rabinstein AA, Freeman WD. Early Absent Pupillary Light Reflexes After Cardiac Arrest in Patients Treated with Therapeutic Hypothermia. Ther Hypothermia Temp Manag. 2016 Aug; 6: (3)116-21.
    View PubMed
  60. Freeman WD, Sebesto J, Tawk RG. Letter to the Editor: Dural arteriovenous fistula mimicking Creutzfeldt-Jakob disease. J Neurosurg 2016 Jul; 125 (1):231-2 Epub 2016 Apr 22
    View PubMed
  61. Lopez Chiriboga AS, Yoon JW, Freeman WD, Odunukan OW, Cheshire WP Jr. Takotsubo cardiomyopathy in the setting of acute hydrocephalus secondary to neurocysticercosis. Clin Auton Res. 2016 Jun; 26 (3):235-41 Epub 2016 Mar 07
    View PubMed
  62. Tawk RG, Grewal SS, Heckman MG, Rawal B, Miller DA, Edmonston D, Ferguson JL, Navarro R, Ng L, Brown BL, Meschia JF, Freeman WD. The Relationship Between Serum Neuron-Specific Enolase Levels and Severity of Bleeding and Functional Outcomes in Patients With Nontraumatic Subarachnoid Hemorrhage. Neurosurgery. 2016 Apr; 78 (4):487-91
    View PubMed
  63. Dredla B, Freeman WD. Ehrlichia Meningitis Mimicking Aneurysmal Subarachnoid Hemorrhage: A Case Study for Medical Decision-Making Heuristics. Neurohospitalist. 2016 Apr; 6 (2):76-9 Epub 2015 Aug 02
    View PubMed
  64. Sridharan M, Wysokinski WE, Pruthi R, Oyen L, Freeman WD, Rabinstein AA, McBane RD. Periprocedural warfarin reversal with prothrombin complex concentrate. Thromb Res. 2016 Mar; 139:160-5.
    View PubMed
  65. Festic E, Soto JS, Pitre LA, Leveton M, Ramsey DM, Freeman WD, Heckman MG, Lee AS. Novel Bedside Phonetic Evaluation to Identify Dysphagia and Aspiration Risk. Chest. 2016 Mar; 149: (3)649-59.
    View PubMed
  66. Siegel J, Edwards E, Mooney L, Smith C, Smith C, Peel JB, Dole A, Maler P, Freeman WD. A feasibility pilot using a mobile personal health assistant (PHA) app to assist stroke patient and caregiver communication after hospital discharge. Mhealth. 2016; 2:31 Epub 2016 Aug 09
    View PubMed
  67. Freeman WD. "Management of intracranial pressure": Erratum CONTINUUM: Lifelong Learning in Neurology. 2015 Dec; 21: (6)1550.
  68. Freeman WD, Brazis PW, Biller J, Masdeu JC, Merrilees GR, Olson S. In Memoriam: Frank A. Rubino, MD. JAMA Neurol. 2015 Nov; 72: (11)1384-5.
    View PubMed
  69. Duello KM, Nagel JP, Thomas CS, Blackshear JL, Freeman WD. Relationship of Troponin T and Age- and Sex-Adjusted BNP Elevation Following Subarachnoid Hemorrhage with 30-Day Mortality. Neurocrit Care. 2015 Aug; 23 (1):59-65
    View PubMed
  70. Grewal SS, Lopez Del Valle EM, Gupta V, Ramon N, Freeman WD, Tawk RG. Neurological Changes with Abnormal Brain Reactivity Following Coiling of Cerebral Aneurysm. Possible Reactivity to Endovascular Devices and Material? J Vasc Interv Neurol. 2015 Jul; 8 (3):28-36
    View PubMed
  71. Arnold SM, Dinkins M, Mooney LH, Freeman WD, Rawal B, Heckman MG, Davis OA. Very early mobilization in stroke patients treated with intravenous recombinant tissue plasminogen activator. J Stroke Cerebrovasc Dis. 2015 Jun; 24: (6)1168-73.
    View PubMed
  72. Dhakal LP, Hodge DO, Nagel J, Mayes M, Richie A, Ng LK, Freeman WD. Erratum to: safety and tolerability of gabapentin for aneurysmal subarachnoid hemorrhage (SAH) headache and meningismus. Neurocrit Care. 2015 Jun; 22 (3):422
    View PubMed
  73. Dhakal LP, Hodge DO, Nagel J, Mayes M, Richie A, Ng LK, Freeman WD. Safety and tolerability of gabapentin for aneurysmal subarachnoid hemorrhage (sah) headache and meningismus. Neurocrit Care. 2015 Jun; 22 (3):414-21
    View PubMed
  74. Dhakal LP, Diaz-Gomez JL, Freeman WD. Role of anesthesia for endovascular treatment of ischemic stroke: do we need neurophysiological monitoring? Stroke. 2015 Jun; 46 (6):1748-54 Epub 2015 May 07
    View PubMed
  75. Dhakal LP, Bourgeois K, Barrett KM, Freeman WD. The "starfield" pattern of cerebral fat embolism from bone marrow necrosis in sickle cell crisis. Neurohospitalist. 2015 Apr; 5 (2):74-6
    View PubMed
  76. Rubin MN, Barrett KM, Freeman WD, Lee Iannotti JK, Channer DD, Rabinstein AA, Demaerschalk BM. Teleneurosonology: a novel application of transcranial and carotid ultrasound. J Stroke Cerebrovasc Dis. 2015 Mar; 24: (3)562-5.
    View PubMed
  77. Cable CA, Freeman WD, Rubin MN, Khoor A, Karnatovskaia LV. A 51-year-old man with seizures and progressive behavioral changes. Chest. 2015 Mar; 147: (3)e86-e89.
    View PubMed
  78. Tawk RG, Grewal SS, Heckman MG, Navarro R, Ferguson JL, Starke EL, Rawal B, Hanel R, Miller D, Wharen RE, Freeman WD. Influence of body mass index and age on functional outcomes in patients with subarachnoid hemorrhage. Neurosurgery. 2015 Feb; 76 (2):136-41
    View PubMed
  79. Pagan RJ, Parikh PP, Mergo PJ, Gerber TC, Mankad R, Freeman WD, Shapiro BP. Emerging role of cardiovascular CT and MRI in the evaluation of stroke. AJR Am J Roentgenol. 2015 Feb; 204(2):269-80.
    View PubMed
  80. Freeman WD. Management of intracranial pressure. CONTINUUM Lifelong Learn. Neurol. 2015; 21(5):1299-323.
  81. Freeman WD, Vatz KA. The future of health care: going to the dogs? Front Neurol. 2015; 6:87 Epub 2015 May 08
    View PubMed
  82. Freeman WD. Cerebral perfusion pressure versus intracranial pressure-driven therapy on outcomes. Crit Care Med 2015 Jan; 43 (1):e29
    View PubMed
  83. Cano EJ, Robinson MT, Eidelman BH, Sebesto JR, Helmer SE, Freeman WD. Asymmetric brain edema after cardiac transplantation: cerebroautoregulatory failure and relative hyperperfusion. Transplant Proc. 2015 Jan-Feb; 47 (1):194-7
    View PubMed
  84. Karnatovskaia LV, Lee AS, Festic E, Kramer CL, Freeman WD. Effect of prolonged therapeutic hypothermia on intracranial pressure, organ function, and hospital outcomes among patients with aneurysmal subarachnoid hemorrhage. Neurocrit Care. 2014 Dec; 21 (3):451-61
    View PubMed
  85. Sierra J, Hanel R, Mooney L, Freeman W. Differential considerations of TCD pulsatility (Gosling's) and resistance (Pourcelot) indices after AVM surgery. J Vasc Interv Neurol. 2014 Nov; 7 (4):41-3
    View PubMed
  86. Karnatovskaia LV, Wartenberg KE, Freeman WD. Therapeutic hypothermia for neuroprotection: history, mechanisms, risks, and clinical applications. Neurohospitalist. 2014 Jul; 4 (3):153-63
    View PubMed
  87. Karnatovskaia LV, Festic E, Freeman WD, Lee AS. Effect of therapeutic hypothermia on gas exchange and respiratory mechanics: a retrospective cohort study. Ther Hypothermia Temp Manag. 2014 Jun; 4: (2)88-95.
    View PubMed
  88. Smith CC, Tatum WO, Gupta V, Pooley RA, Freeman WD. SPECT-negative SIRPIDs: less aggressive neurointensive care? J Clin Neurophysiol. 2014 Jun; 31(3):e6-10.
    View PubMed
  89. Festic E, Siegel J, Stritt M, Freeman WD. The utility of serum procalcitonin in distinguishing systemic inflammatory response syndrome from infection after aneurysmal subarachnoid hemorrhage. Neurocrit Care. 2014 Jun; 20 (3):375-81
    View PubMed
  90. Hocker S, Tatum WO, LaRoche S, Freeman WD. Refractory and super-refractory status epilepticus--an update. Curr Neurol Neurosci Rep. 2014 Jun; 14 (6):452
    View PubMed
  91. Hanel RA, Taussky P, Dixon T, Miller DA, Sapin M, Nordeen JD, Tawk RG, Navarro R, Johns G, Freeman WD. Safety and efficacy of ticagrelor for neuroendovascular procedures. A single center initial experience. J Neurointerv Surg. 2014 May; 6 (4):320-2 Epub 2013 June 14
    View PubMed
  92. Ranasinghe T, Freeman WD. Vein of trolard sign on noncontrast computed tomography in Behcet's disease. Acta Med Acad. 2014; 43: (1)97-8.
    View PubMed
  93. Lewandowski-Belfer JJ, Patel AV, Darracott RM, Jackson DA, Nordeen JD, Freeman WD. Safety and efficacy of repeated doses of 14.6 or 23.4 % hypertonic saline for refractory intracranial hypertension. Neurocrit Care. 2014; 20(3):436-42.
    View PubMed
  94. Jackson DA, Patel AV, Darracott RM, Hanel RA, Freeman WD, Hanley DF. Safety of intraventricular hemorrhage (IVH) thrombolysis based on CT localization of external ventricular drain (EVD) fenestrations and analysis of EVD tract hemorrhage. Neurocrit Care. 2013 Aug; 19 (1):103-10
    View PubMed
  95. Taussky P, Tawk RG, Miller DA, Freeman WD, Hanel RA. New therapies for unruptured intracranial aneurysms. Neurol Clin. 2013 Aug; 31(3):737-47. Epub 2013 May 17.
    View PubMed
  96. Aguilar MI, Kuo RS, Freeman WD. New anticoagulants (dabigatran, apixaban, rivaroxaban) for stroke prevention in atrial fibrillation. Neurol Clin. 2013 Aug; 31(3):659-75.
    View PubMed
  97. Freeman WD, Vatz KA, Griggs RC, Pedley T. The Workforce Task Force report: clinical implications for neurology. Neurology. 2013 Jul 30; 81 (5):479-86 Epub 2013 June 19
    View PubMed
  98. Silva MD, Brazis P, Miller D, Wharen R, Smith CC, Freeman WD. True- true- unrelated? A deplayed onset, complete third-nerve palsy after traumatic subarachnoid hemorrhage. J Vasc Interv Neurol. 2013 Jun; 6(1):22-5.
  99. Nordeen JD, Patel AV, Darracott RM, Johns GS, Taussky P, Tawk RG, Miller DA, Freeman WD, Hanel RA. Clopidogrel Resistance by P2Y12 Platelet Function Testing in Patients Undergoing Neuroendovascular Procedures: Incidence of Ischemic and Hemorrhagic Complications. J Vasc Interv Neurol. 2013 Jun; 6 (1):26-34
    View PubMed
  100. Festic E, Rabinstein AA, Freeman WD, Mauricio EA, Robinson MT, Mandrekar J, Zubair AC, Lee AS, Gajic O. Blood transfusion is an important predictor of hospital mortality among patients with aneurysmal subarachnoid hemorrhage. Neurocrit Care. 2013 Apr; 18 (2):209-15
    View PubMed
  101. Lewandowski-Belfer JJ, Patel AV, Darracott RM, Jackson DA, Nordeen JD, Freeman WD. Safety and efficacy of repeated doses of 14.6 or 23.4% hypertonic saline for refractory intracranial hypertension. Neurocrit Care. 2013.
  102. Cantador AA, Meschia JF, Freeman WD, Tatum WO. Nonconvulsive status with metronidazole The Neurohospitalist. 2013; 3: (4)185-9.
  103. Likosky DJ, Josephson SA, Coleman M, Freeman WD, Biller J. Survey of current neurohospitalist practice. Neurol Clin Pract. 2012 Dec; 2 (4):319-327
    View PubMed
  104. Freeman WD, Barrett KM, Vatz KA, Demaerschalk BM. Future neurohospitalist: teleneurohospitalist. Neurohospitalist. 2012 Oct; 2 (4):132-43
    View PubMed
  105. Douglas VC, Scott BJ, Berg G, Freeman WD, Josephson SA. Effect of a neurohospitalist service on outcomes at an academic medical center. Neurology. 2012 Sep 4; 79(10):988-94. Epub 2012 Aug 22.
    View PubMed
  106. Rahmlow MR, Boylan K, Freeman WD. Diaphragmatic pacing to facilitate ventilator weaning in neuromyelitis optica-associated respiratory failure. Mult Scler Relat Disord. 2012 Jul; 1(3):145-7. Epub 2012 Apr 07.
    View PubMed
  107. Luk ME, Tatum WO, Patel AV, Nau KM, Freeman WD. The safety of lacosamide for treatment of seizures and seizure prophylaxis in adult hospitalized patients. Neurohospitalist. 2012 Jul; 2(3):77-81.
    View PubMed
  108. Lu N, Jackson D, Luke S, Festic E, Hanel RA, Freeman WD. Intraventricular nicardipine for aneurysmal subarachnoid hemorrhage related vasospasm: assessment of 90 days outcome. Neurocrit Care. 2012 Jun; 16 (3):368-75
    View PubMed
  109. Rabinstein AA, Yee AH, Mandrekar J, Fugate JE, de Groot YJ, Kompanje EJ, Shutter LA, Freeman WD, Rubin MA, Wijdicks EF. Prediction of potential for organ donation after cardiac death in patients in neurocritical state: a prospective observational study. Lancet Neurol. 2012 May; 11(5):414-9. Epub 2012 Apr 10.
    View PubMed
  110. Kramer C, Freeman WD, Larson JS, Hoffman-Snyder C, Wellik KE, Hoffman-Snyder C, Demaerschalk BM, Wingerchuk DM. Therapeutic hypothermia for severe traumatic brain injury: a critically appraised topic. Neurologist. 2012 May; 18 (3):173-7
    View PubMed
  111. Carrigan WV 3rd, Barrett K, Freeman WD, Avalon N. Multimodal CT to Differentiate Acute Ischemic Stroke From Stroke Mimics. Neurohospitalist. 2012 Apr; 2 (2):60-1
    View PubMed
  112. Freeman WD, Aguilar MI. Intracranial hemorrhage: diagnosis and management. Neurol Clin. 2012 Feb; 30: (1)211-40, ix.
    View PubMed
  113. Taussky P, O'Neal B, Daugherty WP, Luke S, Thorpe D, Pooley RA, Evans C, Hanel RA, Freeman WD. Validation of frontal near-infrared spectroscopy as noninvasive bedside monitoring for regional cerebral blood flow in brain-injured patients. Neurosurg Focus. 2012 Feb; 32(2):E2.
    View PubMed
  114. Cyrous A, O'Neal B, Freeman WD. New approaches to bedside monitoring in stroke. Expert rev. neurotherapeutics. 2012; 12(8):915-28.
  115. Freeman WD, Dorsher PT, Safford RE, Van Gerpen J, Edwards WD. Combined pergolide-associated valvular heart disease and achilles tendon contractures. Acta Med Acad. 2012; 41(2):228-30.
    View PubMed
  116. Jerath NU, Reddy C, Freeman WD, Jerath AU, Brown RD. Gender differences in presenting signs and symptoms of acute ischemic stroke: a population-based study. Gend Med. 2011 Oct; 8 (5):312-9 Epub 2011 Sept 16
    View PubMed
  117. Chiota NA, Freeman WD, Barrett KM. Hypoxic-ischemic brain injury and prognosis after cardiac arrest. Continuum. 2011 Oct; 17(5):1094-118.
  118. Walsh RD, Barrett KM, Aguilar MI, Lanzino G, Hanel RA, Miller DA, Chong BW, Freeman WD. Intracranial hemorrhage following neuroendovascular procedures with abciximab is associated with high mortality: a multicenter series. Neurocrit Care. 2011 Aug; 15 (1):85-95
    View PubMed
  119. Freeman WD, Aguilar MI. Prevention of cardioembolic stroke. Neurotherapeutics. 2011 Jul; 8 (3):488-502
    View PubMed
  120. Rancier R, Woessner H, Freeman WD. The diffuse hyperdense intracranial circulation sign. Neurohospitalist. 2011 Jul; 1 (3):137
    View PubMed
  121. Tatum WO, Dworetzky BA, Freeman WD, Schomer DL. Artifact: recording EEG in special care units. J Clin Neurophysiol. 2011 Jun; 28(3):264-77.
    View PubMed
  122. Bacani CJ, Freeman WD, Di Trapani RA, Canabal JC, Arasi L, Shine T, Willingham DL. Emergent, controlled lumbar drainage for intracranial pressure monitoring during orthotopic liver transplantation. Neurocrit Care. 2011 Jun; 14 (3):447-52
    View PubMed
  123. Freeman WD, Dawson SB, Raper C, Thiemann K, Josephson SA, Barrett KM. Neurohospitalists reduce length of stay for patients with ischemic stroke. Neurohospitalist. 2011 Apr; 1 (2):67-70
    View PubMed
  124. Freeman WD, Nolte CM, Matthews BR, Coleman M, Corboy JR. Results of the American Academy of Neurology resident survey. Neurology. 2011 Mar 29; 76(13):e61-7.
    View PubMed
  125. Chiota NA, Freeman WD, Barrett K. Earlier Hypothermia Attainment is Associated with Improved Outcomes after Cardiac Arrest. J Vasc Interv Neurol. 2011 Jan; 4 (1):14-7
    View PubMed
  126. Mauricio EA, Freeman WD. Status epilepticus in the elderly: differential diagnosis and treatment. Neuropsychiatr Dis Treat. 2011; 7:161-6 Epub 2011 Mar 29
    View PubMed
  127. Freeman WD, Josephson SA. The birth of neurohospitalists. Neurohospitalist. 2011 Jan; 1 (1):5-7
    View PubMed
  128. Smith EH, Gavrilov DK, Oglesbee D, Freeman WD, Vavra MW, Matern D, Tortorelli S. An adult onset case of alpha-methyl-acyl-CoA racemase deficiency. J Inherit Metab Dis. 2010 Dec; 33 Suppl 3:S349-53 Epub 2010 Sept 04
    View PubMed
  129. Aguilar MI, Freeman WD. Spontaneous intracerebral hemorrhage. Semin Neurol. 2010 Nov; 30(5):555-64. Epub 2011 Jan 04.
    View PubMed
  130. Freeman WD, Dawson SB, Flemming KD. The ABC's of stroke complications. Semin Neurol. 2010 Nov; 30(5):501-10. Epub 2011 Jan 04.
    View PubMed
  131. Robinson MT, Rabinstein AA, Meschia JF, Freeman WD. Safety of recombinant activated factor VII in patients with warfarin-associated hemorrhages of the central nervous system. Stroke. 2010 Jul; 41: (7)1459-63.
    View PubMed
  132. Freeman WD, Vatz KA. The future of neurology. Neurol Clin. 2010 May; 28(2):537-61.
    View PubMed
  133. Aguilar MI, Freeman WD. Treatment of coagulopathy in intracranial hemorrhage. Curr Treat Options Neurol. 2010 Mar; 12 (2):113-28
    View PubMed
  134. Albright KC, Freeman WD, Kruse BT. Cerebral venous thrombosis. J Emerg Med. 2010 Feb; 38: (2)238-9.
    View PubMed
  135. Barrett KM, Freeman WD. Emerging subspecialties in neurology: neurohospitalist. Neurology. 2010 Jan 12; 74(2):e9-10.
    View PubMed
  136. Freeman WD, Aguilar MI. Anticoagulation Therapy for Stroke: Risks and Benefits in the Aged. Aging Health. 2010.
  137. Freeman WD, Aguilar M. Anticoagulation therapy for cardioembolic stroke prevention in the elderly: Defining benefits and risks. Aging Health. 2010; 6(4):439-50.
  138. Freeman WD, Palmer S, Freeman ML, Barrett KM. Reversible delayed hypoxic leukoencephalopathy associated with methadone overdose. Acta Medica Academica. 2010; 39(1).
  139. Likosky D, Shulman S, Restrepo L, Freeman WD. Survey of neurohospitalists: Subspecialty definition and practice characteristics. Frontiers in Neurology. 2010; Jun:9.
  140. Mateen FJ, Nasser M, Spencer BR, Freeman WD, Shuaib A, Demaerschalk BM, Wijdicks EF. Outcomes of intravenous tissue plasminogen activator for acute ischemic stroke in patients aged 90 years or older. Mayo Clin Proc. 2009 Apr; 84 (4):334-8
    View PubMed
  141. Rowley M, Riutort K, Shapiro D, Casler J, Festic E, Freeman WD. Methylene blue-associated serotonin syndrome: a 'green' encephalopathy after parathyroidectomy. Neurocrit Care. 2009; 11 (1):88-93 Epub 2009 Mar 05
    View PubMed
  142. Nau KM, Divertie GD, Valentino AK, Freeman WD. Safety and efficacy of levetiracetam for critically ill patients with seizures. Neurocrit Care. 2009; 11 (1):34-7 Epub 2009 Jan 29
    View PubMed
  143. Spector AR, Freeman WD, Cheshire WP. The stroke that struck back: an unusual alien hand presentation. J Stroke Cerebrovasc Dis. 2009 Jan; 18(1):72-3.
    View PubMed
  144. Ng HK, Hanel R, Freeman W. Prolonged Mild-to-Moderate Hypothermia for Refractory Intracranial Hypertension. J Vasc Interv Neurol. 2009 Jan; 2 (1):142-6
    View PubMed
  145. Rahmlow M, Shuster EA, Dominik J, Deen HG Jr, Dickson DW, Aksamit AJ Jr, Robles HA, Freeman WD. Leflunomide-associated progressive multifocal leukoencephalopathy. Arch Neurol. 2008 Nov; 65 (11):1538-9
    View PubMed
  146. Freeman WD, Aguilar MI. Stroke prevention in atrial fibrillation and other major cardiac sources of embolism. Neurol Clin. 2008 Nov; 26(4):1129-60, x-xi.
    View PubMed
  147. Valentino AK, Nau KM, Miller DA, Hanel RA, Freeman W. Repeated dosing of 23.4% hypertonic saline for refractory intracranial hypertension. A case report. J Vasc Interv Neurol. 2008 Oct; 1 (4):113-7
    View PubMed
  148. Barrett KM, Freeman WD. 71-year-old woman with loss of right-sided vision and cognitive deficits. Mayo Clin Proc. 2008 Jun; 83(6):708-11.
    View PubMed
  149. Konieczny PL, Eidelman BH, Freeman WD. Teaching video neuroimage: Foix-Chavany-Marie syndrome. Neurology. 2008 May 20; 70: (21)e88.
    View PubMed
  150. Freeman WD, Gronseth G, Eidelman BH. Invited article: is it time for neurohospitalists? Neurology. 2008 Apr 8; 70 (15):1282-8 Epub 2008 Mar 12
    View PubMed
  151. Freeman WD, Aguilar MI. Management of warfarin-related intracerebral hemorrhage. Expert Rev Neurother. 2008 Feb; 8(2):271-90.
    View PubMed
  152. Manno EM, Rabinstein AA, Wijdicks EF, Brown AW, Freeman WD, Lee VH, Weigand SD, Keegan MT, Brown DR, Whalen FX, Roy TK, Hubmayr RD. A prospective trial of elective extubation in brain injured patients meeting extubation criteria for ventilatory support: a feasibility study. Crit Care. 2008; 12 (6):R138 Epub 2008 Nov 10
    View PubMed
  153. Freeman WD, Barrett KM, Bestic JM, Meschia JF, Broderick DF, Brott TG. Computer-assisted volumetric analysis compared with ABC/2 method for assessing warfarin-related intracranial hemorrhage volumes. Neurocrit Care. 2008; 9 (3):307-12
    View PubMed
  154. Aguilar MI, Freeman WD. Warfarin-related intracerebral hemorrhage: How to proceed. Aging Health. 2008; 4(3):299-310.
  155. Barrett KM, Freeman WD, Weindling SM, Brott TG, Broderick DF, Heckman MG, Crook JE, Divertie GD, Meschia JF. Brain injury after cardiopulmonary arrest and its assessment with diffusion-weighted magnetic resonance imaging. Mayo Clin Proc. 2007 Jul; 82(7):828-35.
    View PubMed
  156. Gill DJ, Freeman WD, Thoresen P, Corboy JR. Residency training the neurology resident case log: a national survey of neurology residents. Neurology. 2007 May 22; 68(21):E32-3.
    View PubMed
  157. Linos K, Foot C, Ziegenfuss M, Freeman WD, Tan KM. Critical illness weakness: Common questions. Curr Anaesth Crit Care. 2007; 18(5-6):252-60.
  158. Linos K, Fraser J, Freeman WD, Foot C. Care of the brain-dead organ donor. Curr Anaesth Crit Care. 2007; 18(5-6):284-94.
  159. Heaney M, Foot C, Freeman WD, Fraser J. Ethical issues in withholding and withdrawing life-prolonging medical treatment in the ICU. Curr Anaesth Crit Care. 2007; 18(5-6):277-83.
  160. Freeman WD, Tan KM, Glass GA, Linos K, Foot C, Ziegenfuss M. ICU management of patients with Parkinson's disease or Parkinsonism. Curr Anaesth Crit Care. 2007; 18(5-6):227-36.
  161. Aguilar MI, Hart RG, Kase CS, Freeman WD, Hoeben BJ, Garcia RC, Ansell JE, Mayer SA, Norrving B, Rosand J, Steiner T, Wijdicks EF, Yamaguchi T, Yasaka M. Treatment of warfarin-associated intracerebral hemorrhage: literature review and expert opinion. Mayo Clin Proc. 2007 Jan; 82: (1)82-92.
    View PubMed
  162. Freeman WD, Sen S, Roy TK, Wijdicks EF. Cluster breathing associated with bihemispheric infarction and sparing of the brainstem. Arch Neurol. 2006 Oct; 63(10):1487-90.
    View PubMed
  163. Freeman WD, Brott TG. Modern treatment options for intracerebral hemorrhage. Curr Treat Options Neurol. 2006 Mar; 8 (2):145-57
    View PubMed
  164. Baba Y, Hentschel K, Freeman WD, Broderick DF, Wszolek ZK. Large paraspinal and iliopsoas muscle hematomas. Archives of Neurology. 2005 Aug; 62(8):1306.
    View PubMed
  165. Freeman WD, Chabolla DR. 36-Year-old woman with loss of consciousness, fever, and tachycardia. Mayo Clin Proc. 2005 May; 80 (5):667-70
    View PubMed
  166. Freeman WD, Cheshire WP. A callused clue fingers the diagnosis. Arch Neurol. 2005 Mar; 62(3):491.
    View PubMed
  167. Freeman WD, Maramattom B, Czervionke L, Manno EM. Pituitary apoplexy. Neurocrit Care. 2005; 3 (2):174-6
    View PubMed
  168. Freeman WD, Brott TG, Barrett KM, Castillo PR, Deen HG Jr, Czervionke LF, Meschia JF. Recombinant factor VIIa for rapid reversal of warfarin anticoagulation in acute intracranial hemorrhage. Mayo Clin Proc. 2004 Dec; 79: (12)1495-500.
    View PubMed