Publications

  1. Berg WA, Rafferty EA, Friedewald SM, Hruska CB, Rahbar H. Screening Algorithms in Dense Breasts: AJR Expert Panel Narrative Review. AJR Am J Roentgenol. 2020 Sep 9 Epub 2020 Sept 09
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  2. Hruska CB, Geske JR, Conners AL, Whaley DH, Rhodes DJ, O'Connor MK, Carter RE, Scott CG, Vachon CM. Background Parenchymal Uptake on Molecular Breast Imaging and Breast Cancer Risk: A Cohort Study. AJR Am J Roentgenol. 2020 Jul 29 Epub 2020 July 29
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  3. Gastounioti A, Kasi CD, Scott CG, Brandt KR, Jensen MR, Hruska CB, Wu FF, Norman AD, Conant EF, Winham SJ, Kerlikowske K, Kontos D, Vachon CM. Evaluation of LIBRA Software for Fully Automated Mammographic Density Assessment in Breast Cancer Risk Prediction. Radiology. 2020 Jul; 296 (1):24-31 Epub 2020 May 12
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  4. Rhodes DJ, Jenkins SM, Hruska CB, Vachon CM, Breitkopf CR. Breast Density Awareness, Knowledge, and Attitudes Among US Women: National Survey Results Across 5 Years. J Am Coll Radiol. 2020 Mar; 17 (3):391-404 Epub 2019 Nov 19
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  5. Tao AT, Hruska CB, Conners AL, Hunt KN, Swanson TN, Tran TD, Manduca A, Borges L, Maidment ADA, Lake D, Johnson MP, Carter RE, Rhodes DJ, O'Connor MK. Dose Reduction in Molecular Breast Imaging With a New Image-Processing Algorithm. AJR Am J Roentgenol. 2020 Jan; 214 (1):185-193 Epub 2019 Oct 08
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  6. Hunt KN, Hruska CB, Johnson MP, Conners AL, O'Connor MK, Rhodes DJ, Basappa S, Wahner-Roedler D. Molecular Breast Imaging in Patients with Suspicious Calcifications Journal of Breast Imaging. 2019; 1(4):303-309.
  7. Brandt KR, Scott CG, Miglioretti DL, Jensen MR, Mahmoudzadeh AP, Hruska C, Ma L, Wu FF, Cummings SR, Norman AD, Engmann NJ, Shepherd JA, Winham SJ, Kerlikowske K, Vachon CM. Automated volumetric breast density measures: differential change between breasts in women with and without breast cancer. Breast Cancer Res. 2019 Oct 28; 21 (1):118
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  8. Hruska CB. Let’s Get Real About Molecular Breast Imaging and Radiation Risk Radiology: Imaging Cancer. 2019.
  9. Engmann NJ, Scott CG, Jensen MR, Winham S, Miglioretti DL, Ma L, Brandt K, Mahmoudzadeh A, Whaley DH, Hruska C, Wu F, Norman AD, Hiatt RA, Heine J, Shepherd J, Pankratz VS, Vachon CM, Kerlikowske K. Combined effect of volumetric breast density and body mass index on breast cancer risk. Breast Cancer Res Treat. 2019 Aug; 177 (1):165-173 Epub 2019 May 25
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  10. Engmann NJ, Scott C, Jensen MR, Winham SJ, Ma L, Brandt KR, Mahmoudzadeh A, Whaley DH, Hruska CB, Wu FF, Norman AD, Hiatt RA, Heine J, Shepherd J, Pankratz VS, Miglioretti DL, Kerlikowske K, Vachon CM. Longitudinal Changes in Volumetric Breast Density in Healthy Women across the Menopausal Transition. Cancer Epidemiol Biomarkers Prev. 2019 Aug; 28 (8):1324-1330 Epub 2019 June 11
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  11. Hruska CB, Hunt KN, Conners AL, Geske JR, Brandt KR, Degnim AC, Vachon CM, O'Connor MK, Rhodes DJ. Impact of short-term low-dose tamoxifen on molecular breast imaging background parenchymal uptake: a pilot study. Breast Cancer Res. 2019 Mar 8; 21 (1):38 Epub 2019 Mar 08
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  12. Samreen N, Hunt KN, Hruska CB, Rhodes DJ. Molecular breast imaging detected invasive lobular carcinoma in dense breasts: A case report. Clin Case Rep. 2019 Mar; 7 (3):442-444 Epub 2019 Jan 28
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  13. Carter RE, Attia ZI, Geske JR, Conners AL, Whaley DH, Hunt KN, O'Connor MK, Rhodes DJ, Hruska CB. Classification of Background Parenchymal Uptake on Molecular Breast Imaging Using a Convolutional Neural Network. JCO Clin Cancer Inform. 2019 Feb; 3:1-11
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  14. Kontos D, Winham SJ, Oustimov A, Pantalone L, Hsieh MK, Gastounioti A, Whaley DH, Hruska CB, Kerlikowske K, Brandt K, Conant EF, Vachon CM. Radiomic Phenotypes of Mammographic Parenchymal Complexity: Toward Augmenting Breast Density in Breast Cancer Risk Assessment. Radiology. 2019 Jan; 290 (1):41-49 Epub 2018 Oct 30
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  15. Nardinger SM, Tran TD, Swanson TN, Ellingson LR, Solberg CM, O'Connor MK, Hruska CB. Guidelines for Quality Control Testing of Molecular Breast Imaging Systems. J Nucl Med Technol. 2018 Dec; 46 (4):349-354 Epub 2018 June 08
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  16. Tran TD, Ellingson LR, Swanson TN, Solberg CM, O'Connor MK, Hruska CB. Molecular Breast Imaging: Administered Activity Does Not Require Adjustment Based on Patient Size. J Nucl Med Technol. 2018 Sep; 46 (3):265-267 Epub 2018 Mar 29
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  17. Hruska CB, Geske JR, Swanson TN, Mammel AN, Lake DS, Manduca A, Conners AL, Whaley DH, Scott CG, Carter RE, Rhodes DJ, O'Connor MK, Vachon CM. Quantitative background parenchymal uptake on molecular breast imaging and breast cancer risk: a case-control study. Breast Cancer Res. 2018 Jun 5; 20 (1):46 Epub 2018 June 05
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  18. Swanson TN, Tran TD, Hruska CB, Solberg CM, Rhodes DJ, Hunt KN, Conners AL, O'Connor MK. Patient Acceptance of Half-dose Vs. Half-time Molecular Breast Imaging. J Med Imaging Radiat Sci. 2018 Mar; 49 (1):39-43 Epub 2017 Sept 13
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  19. Swanson T, Tran TD, Ellingson L, O'Connor MK, Rhodes DJ, Hunt KN, Conners AL, Hruska CB. BEST PRACTICES IN MOLECULAR BREAST IMAGING: A GUIDE FOR TECHNOLOGISTS. J Nucl Med Technol. 2018 Feb 2 Epub 2018 Feb 02
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  20. O'Connor MK, Morrow MMB, Hunt KN, Boughey JC, Wahner-Roedler DL, Conners AL, Rhodes DJ, Hruska CB. Comparison of Tc-99m maraciclatide and Tc-99m sestamibi molecular breast imaging in patients with suspected breast cancer. EJNMMI Res. 2017 Dec; 7 (1):5 Epub 2017 Jan 14
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  21. Engmann NJ, Scott CG, Jensen MR, Ma L, Brandt KR, Mahmoudzadeh AP, Malkov S, Whaley DH, Hruska CB, Wu FF, Winham SJ, Miglioretti DL, Norman AD, Heine JJ, Shepherd J, Pankratz VS, Vachon CM, Kerlikowske K. Longitudinal Changes in Volumetric Breast Density with Tamoxifen and Aromatase Inhibitors. Cancer Epidemiol Biomarkers Prev. 2017 Jun; 26 (6):930-937 Epub 2017 Feb 01
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  22. O'Connor MK, Morrow MM, Tran T, Hruska CB, Conners AL, Hunt KN. Technical Note: Development of a combined molecular breast imagingultrasound system for diagnostic evaluation of MBI-detected lesions. Med Phys. 2017 Feb; 44: (2)451-459.
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  23. Hruska CB. Molecular Breast Imaging for Screening in Dense Breasts: State of the Art and Future Directions. AJR Am J Roentgenol. 2017 Feb; 208 (2):275-283 Epub 2016 Oct 20
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  24. Rhodes DJ, Hruska CB, Conners AL, Hunt KN, O'Connor MK. Benefit-to-Radiation Risk for Breast Screening Tests Is a Flawed Concept. Radiology 2016 Dec; 281 (3):978-980
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  25. Brandt KR, Scott CG, Ma L, Mahmoudzadeh AP, Jensen MR, Whaley DH, Wu FF, Malkov S, Hruska CB, Norman AD, Heine J, Shepherd J, Pankratz VS, Kerlikowske K, Vachon CM. Comparison of Clinical and Automated Breast Density Measurements: Implications for Risk Prediction and Supplemental Screening. Radiology. 2016 Jun; 279 (3):710-9 Epub 2015 Dec 22
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  26. Long Z, Conners AL, Hunt KN, Hruska CB, O'Connor MK. Performance characteristics of dedicated molecular breast imaging systems at low doses. Med Phys. 2016 Jun; 43: (6)3062-3070.
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  27. Hruska CB, Scott CG, Conners AL, Whaley DH, Rhodes DJ, Carter RE, O'Connor MK, Hunt KN, Brandt KR, Vachon CM. Background parenchymal uptake on molecular breast imaging as a breast cancer risk factor: a case-control study. Breast Cancer Res. 2016 Apr 26; 18 (1):42
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  28. Hruska CB, O'Connor MK. Curies, and Grays, and Sieverts, Oh My: A Guide for Discussing Radiation Dose and Risk of Molecular Breast Imaging. J Am Coll Radiol. 2015 Oct; 12: (10)1103-5.
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  29. Conners AL, Jones KN, Hruska CB, Geske JR, Boughey JC, Rhodes DJ. Direct-Conversion Molecular Breast Imaging of Invasive Breast Cancer: Imaging Features, Extent of Invasive Disease, and Comparison Between Invasive Ductal and Lobular Histology. AJR Am J Roentgenol. 2015 Sep; 205(3):W374-81.
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  30. Hruska CB, Conners AL, Vachon CM, O'Connor MK, Shuster LT, Bartley AC, Rhodes DJ. Effect of menstrual cycle phase on background parenchymal uptake at molecular breast imaging. Acad Radiol. 2015 Sep; 22 (9):1147-56 Epub 2015 June 22
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  31. Zhang GS, Wang W, Shin S, Hruska CB, Son SH. Fourier irregularity index: a new approach to measure tumor mass irregularity in breast mammogram images. Multimedia Tools And Applications. 2015 Jun; 74(11):3783-98.
  32. Hruska CB, Conners AL, Jones KN, O'Connor MK, Moriarty JP, Boughey JC, Rhodes DJ. Diagnostic workup and costs of a single supplemental molecular breast imaging screen of mammographically dense breasts. AJR Am J Roentgenol. 2015 Jun; 204 (6):1345-53
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  33. Leng S, Hruska CB, McCollough CH. Use of ionizing radiation in screening examinations for coronary artery calcium and cancers of the lung, colon, and breast. Semin Roentgenol. 2015 Apr; 50: (2)148-60.
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  34. O'Connor MK, Hruska CB, Tran TD, Swanson T, Conners AL, Jones K, Rhodes DJ. Factors influencing the uptake of 99mTc-sestamibi in breast tissue on molecular breast imaging. J Nucl Med Technol. 2015 Mar; 43(1):13-20. Epub 2015 Jan 22.
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  35. Hruska CB, Rhodes DJ, Conners AL, Jones KN, Carter RE, Lingineni RK, Vachon CM. Background parenchymal uptake during molecular breast imaging and associated clinical factors. AJR Am J Roentgenol. 2015 Mar; 204 (3):W363-70
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  36. Rhodes DJ, Hruska CB, Conners AL, Tortorelli CL, Maxwell RW, Jones KN, Toledano AY, O'Connor MK. Journal club: molecular breast imaging at reduced radiation dose for supplemental screening in mammographically dense breasts. AJR Am J Roentgenol. 2015 Feb; 204 (2):241-51
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  37. Hruska CB, Conners AL, Jones KN, Weinmann AL, Lingineni RK, Carter RE, Rhodes DJ, O'Connor MK. Half-time Tc-99m sestamibi imaging with a direct conversion molecular breast imaging system. EJNMMI Res. 2014 Jan 15; 4 (1):5
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  38. Swanson TN, Troung DT, Paulsen A, Hruska CB, O'Connor MK. Adsorption of 99mTc-sestamibi onto plastic syringes: evaluation of factors affecting the degree of adsorption and their impact on clinical studies. J Nucl Med Technol. 2013 Dec; 41 (4):247-52 Epub 2013 Nov 08
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  39. Mitchell D, Hruska CB, Boughey JC, Wahner-Roedler DL, Jones KN, Tortorelli C, Conners AL, O'Connor MK. 99mTc-sestamibi using a direct conversion molecular breast imaging system to assess tumor response to neoadjuvant chemotherapy in women with locally advanced breast cancer. Clin Nucl Med. 2013 Dec; 38 (12):949-56
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  40. Hruska CB, O'Connor MK. Nuclear imaging of the breast: translating achievements in instrumentation into clinical use. Med Phys. 2013 May; 40 (5):050901
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  41. Weinmann AL, Hruska CB, Conners AL, O'Connor MK. Collimator design for a dedicated molecular breast imaging-guided biopsy system: proof-of-concept. Med Phys. 2013 Jan; 40 (1):012503
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  42. Conners AL, Maxwell RW, Tortorelli CL, Hruska CB, Rhodes DJ, Boughey JC, Berg WA. Gamma camera breast imaging lexicon. AJR Am J Roentgenol. 2012 Dec; 199: (6)W767-74.
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  43. Zhang G, Shin S, Wang W, Hruska C, Choi HD. A new fourier-based approach to measure irregularity of breast masses in mammograms. Proceeding of the 2012 ACM Research in Applied Computation Symposium, RACS 2012. 2012; 153-7.
  44. Hruska CB, Rhodes DJ, Collins DA, Tortorelli CL, Askew JW, O'Connor MK. Evaluation of molecular breast imaging in women undergoing myocardial perfusion imaging with Tc-99m sestamibi. J Womens Health (Larchmt). 2012 Jul; 21: (7)730-8.
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  45. Conners AL, Hruska CB, Tortorelli CL, Maxwell RW, Rhodes DJ, Boughey JC, Berg WA. Lexicon for standardized interpretation of gamma camera molecular breast imaging: observer agreement and diagnostic accuracy. Eur J Nucl Med Mol Imaging. 2012 Jun; 39 (6):971-82
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  46. Hruska CB, Weinmann AL, O'Connor MK. Proof of concept for low-dose molecular breast imaging with a dual-head CZT gamma camera. Part I. Evaluation in phantoms. Med Phys. 2012 Jun; 39 (6):3466-75
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  47. Hruska CB, Weinmann AL, Tello Skjerseth CM, Wagenaar EM, Conners AL, Tortorelli CL, Maxwell RW, Rhodes DJ, O'Connor MK. Proof of concept for low-dose molecular breast imaging with a dual-head CZT gamma camera. Part II. Evaluation in patients. Med Phys. 2012 Jun; 39 (6):3476-83
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  48. Wahner-Roedler DL, Boughey JC, Hruska CB, Chen B, Rhodes DJ, Tortorelli CL, Maxwell RW, Cha SS, O'Connor MK. The use of molecular breast imaging to assess response in women undergoing neoadjuvant therapy for breast cancer: a pilot study. Clin Nucl Med. 2012 Apr; 37 (4):344-50
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  49. Brodt JK, Rhodes DJ, Glazebrook KN, Hruska C, O'Connor M, Boughey JC. Radiologic and pathologic images of mammary fibromatosis. Breast J. 2011 Mar-Apr; 17(2):207-9. Epub 2011 Jan 27.
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  50. Wahner-Roedler DL, Hruska CB, O'Connor MK, Phillips SW, Whaley DH, Johnson RE, Degnim AC, Boughey JC, Rhodes DJ. Molecular breast imaging for women presenting with a history of non-reproducible bloody nipple discharge and negative findings on routine imaging studies: A pilot study. Journal of Surgical Radiology. 2011; 2(1):92-9.
  51. Rhodes DJ, Hruska CB, Phillips SW, Whaley DH, O'Connor MK. Dedicated dual-head gamma imaging for breast cancer screening in women with mammographically dense breasts. Radiology. 2011 Jan; 258: (1)106-18.
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  52. O'Connor MK, Li H, Rhodes DJ, Hruska CB, Clancy CB, Vetter RJ. Comparison of radiation exposure and associated radiation-induced cancer risks from mammography and molecular imaging of the breast. Med Phys. 2010 Dec; 37 (12):6187-98
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  53. Boughey JC, Tortorelli C, Hruska C, O'Connor M, Rhodes D. Molecular breast imaging in pseudoangiomatous stromal hyperplasia. Journal of Surgical Radiology. 2010; 1(1).
  54. O'Connor MK, Hruska CB, Weinmann A, Manduca A, Rhodes DJ. Development of radiation dose reduction techniques for cadmium zinc telluride detectors in molecular breast imaging. Proceedings of SPIE - The International Society for Optical Engineering. 2010; 7806:780603.
  55. O'Connor M, Rhodes D, Hruska C. Molecular breast imaging. Expert Rev Anticancer Ther. 2009 Aug; 9 (8):1073-80
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  56. Kemp BJ, Hruska CB, McFarland AR, Lenox MW, Lowe VJ. NEMA NU 2-2007 performance measurements of the Siemens Inveon preclinical small animal PET system. Phys Med Biol. 2009 Apr 21; 54 (8):2359-76 Epub 2009 Mar 25
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  57. Weinmann AL, Hruska CB, O'Connor MK. Design of optimal collimation for dedicated molecular breast imaging systems. Med Phys. 2009 Mar; 36 (3):845-56
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  58. Hruska CB, Phillips SW, Whaley DH, Rhodes DJ, O'Connor MK. Molecular breast imaging: use of a dual-head dedicated gamma camera to detect small breast tumors. AJR Am J Roentgenol. 2008 Dec; 191 (6):1805-15
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  59. Hruska CB, Boughey JC, Phillips SW, Rhodes DJ, Wahner-Roedler DL, Whaley DH, Degnim AC, O'Connor MK. Scientific Impact Recognition Award: Molecular breast imaging: a review of the Mayo Clinic experience. Am J Surg. 2008 Oct; 196 (4):470-6 Epub 2008 Aug 23
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  60. Hruska CB, O'Connor MK. Quantification of lesion size, depth, and uptake using a dual-head molecular breast imaging system. Med Phys. 2008 Apr; 35 (4):1365-76
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  61. Hruska CB, O'Connor MK. A Monte Carlo model for energy spectra analysis in dedicated nuclear breast imaging. IEEE Trans Nucl Sci. 2008 Feb; 55(1 Part 2):491-500.
  62. O'Connor MK, Phillips SW, Hruska CB, Rhodes DJ, Collins DA. Molecular breast imaging: advantages and limitations of a scintimammographic technique in patients with small breast tumors. Breast J. 2007 Jan-Feb; 13: (1)3-11.
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  63. Hruska CB, O'Connor MK. Molecular breast imaging - A phantom study on the impact of collimator selection on the detection of sub-10mm breast lesions. Nuclear Instruments & Methods in Physics Research Section A-Accelerators Spectrometers Detectors & Associated Equipment. 2006 Dec 20; 569(2 Special Issue SI):250-4.
  64. Hruska CB, O'Connor MK. Effect of collimator selection on tumor detection for dedicated nuclear breast imaging systems. IEEE Trans Nucl Sci. 2006 Oct; 53(5 Part 1):2680-9.
  65. O'Connor MK, Wagenaar DJ, Hruska CB, Phillips SW, Caravaglia G, Rhodes DJ. Molecular breast imaging using a dedicated high-performance instrument. Proceeding of SPIE. 2006; 6319:63191D1-63191D14.
  66. Hruska CB, O'connor MK. CZT detectors: How important is energy resolution for nuclear breast imaging? Phys Med. 2006; 21 Suppl 1:72-5.
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  67. Hruska CB, O'Connor MK, Collins DA. Comparison of small field of view gamma camera systems for scintimammography. Nucl Med Commun. 2005 May; 26 (5):441-5
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  68. O'Connor MK, Hruska CB. Effect of tomographic orbit and type of rotation on apparent myocardial activity. Nucl Med Commun. 2005 Jan; 26 (1):25-30
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