Publications

  1. Zhao W, Wang K, Chen H, Xu J, Wen L, Wu Y, Chen W, Liu H, Liu Y, Zhang J, Lieske JC, Zhang L, Zhang X, Mai H. Revolutionizing nephrocalcinosis treatment: IL-10 engineered macrophages as a novel therapeutic approach. Bioeng Transl Med. 2026 Jan; 11 (1):e70047 Epub 2025 July 10
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  2. Wen A, Lu Q, Chuang YN, Wang G, Yuan J, Zhang J, Wang L, Fu S, Miller KD, Jia H, Bedrick SD, Hersh WR, Roberts KE, Hu X, Liu H. Context matching is not reasoning when performing generalized clinical evaluation of generative language models. NPJ Digit Med. 2025 Dec 27; 9 (1):71
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  3. Edmiston T, Bath MF, Caceres E, Nuno-Guzman CM, Baderhabusha DU, Khajanchi M, Amoako J, Kohler K, Hashi AS, Carenzo L, Zhang Z, Marsden M, Saleh R, Hammer CC, Hobbs L, Smith BG, Hutchinson P, Weiser T, Perkins ZB, Hardcastle TC, Bashford T, GOAL-Trauma Collaborative. Variation in global trauma care: a survey of 187 hospitals across 51 countries. BMJ Glob Health. 2025 Nov 9; 10 (11) Epub 2025 Nov 09
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  4. Ewing AG, Joffe D, Blitshteyn S, Brooks AES, Wist J, Bar-Yam Y, Bilodeau S, Curtin J, Duncan R, Faghy M, Galland L, Pretorius E, Salamon S, Buonsenso D, Hastie C, Kane B, Khan MA, Lal A, Lau D, MacIntyre R, McFarland S, Munblit D, Nicholson J, Ollila HM, Putrino D, Rosario A, Tan T, Long COVID consensus expert panel (Table S1). Long COVID clinical evaluation, research and impact on society: a global expert consensus. Ann Clin Microbiol Antimicrob 2025 Apr 20; 24 (1):27
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  5. Xu J, Kato K, Raymond E, Hubner RA, Shu Y, Pan Y, Park SR, Ping L, Jiang Y, Zhang J, Wu X, Yao Y, Shen L, Kojima T, Gotovkin E, Ishihara R, Wyrwicz L, Van Cutsem E, Jimenez-Fonseca P, Lin CY, Wang L, Shi J, Li L, Yoon HH. Tislelizumab plus chemotherapy versus placebo plus chemotherapy as first-line treatment for advanced or metastatic oesophageal squamous cell carcinoma (RATIONALE-306): a global, randomised, placebo-controlled, phase 3 study. Lancet Oncol. 2023 May; 24 (5):483-495 Epub 2023 Apr 17
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  6. Loehr A, Patnaik A, Campbell D, Shapiro J, Bryce AH, McDermott R, Sautois B, Vogelzang NJ, Bambury RM, Voog E, Zhang J, Piulats JM, Hussain A, Ryan CJ, Merseburger AS, Daugaard G, Heidenreich A, Fizazi K, Higano CS, Krieger LE, Sternberg CN, Watkins SP, Despain D, Simmons AD, Dowson M, Golsorkhi T, Chowdhury S, Abida W. Response to Rucaparib in BRCA-Mutant Metastatic Castration-Resistant Prostate Cancer Identified by Genomic Testing in the TRITON2 Study. Clin Cancer Res 2021 Dec 15; 27 (24):6677-6686 Epub 2021 Oct 01
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  7. DeJong SR, Bakkum-Gamez JN, Clayton AC, Henry MR, Keeney GL, Zhang J, Kroneman TN, Laughlin-Tommaso SK, Ahlberg LJ, VanOosten AL, Weaver AL, Wentzensen N, Kerr SE. Tao brush endometrial cytology is a sensitive diagnostic tool for cancer and hyperplasia among women presenting to clinic with abnormal uterine bleeding. Cancer Med. 2021 Oct; 10 (20):7040-7047 Epub 2021 Sept 16
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  8. Zhang J, Gao K, Xie H, Wang D, Zhang P, Wei T, Yan Y, Pan Y, Ye W, Chen H, Shi Q, Li Y, Zhao SM, Hou X, Weroha SJ, Wang Y, Zhang J, Karnes RJ, He HH, Wang L, Wang C, Huang H. SPOP mutation induces DNA methylation via stabilizing GLP/G9a. Nat Commun. 2021 Sep 29; 12 (1):5716 Epub 2021 Sept 29
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  9. Huang Z, Tang B, Yang Y, Yang Z, Shi L, Bai Y, Yan B, Karnes RJ, Zhang J, Jimenez R, Wang L, Wei Q, Yang J, Xu W, Jia Z, Huang H. MAP3K7-IKK Inflammatory Signaling Modulates AR Protein Degradation and Prostate Cancer Progression. Cancer Res. 2021 Sep 1; 81 (17):4471-4484 Epub 2021 June 22
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  10. Shi L, Yan Y, He Y, Yan B, Pan Y, Orme JJ, Zhang J, Xu W, Pang J, Huang H. Mutated SPOP E3 Ligase Promotes 17betaHSD4 Protein Degradation to Drive Androgenesis and Prostate Cancer Progression. Cancer Res. 2021 Jul 1; 81 (13):3593-3606 Epub 2021 Mar 24
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  11. Gjyrezi A, Galletti G, Zhang J, Worroll D, Sigouros M, Kim S, Cooley V, Ballman KV, Ocean AJ, Shah MA, Scandura JM, Sboner A, Nanus DM, Beltran H, Tagawa S, Giannakakou P. Androgen receptor variant shows heterogeneous expression in prostate cancer according to differentiation stage. Commun Biol. 2021 Jun 24; 4 (1):785 Epub 2021 June 24
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  12. Tang B, Sun R, Wang D, Sheng H, Wei T, Wang L, Zhang J, Ho TH, Yang L, Wei Q, Huang H. ZMYND8 preferentially binds phosphorylated EZH2 to promote a PRC2-dependent to -independent function switch in hypoxia-inducible factor-activated cancer. Proc Natl Acad Sci U S A. 2021 Feb 23; 118 (8)
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  13. Ma C, Hokutan K, Shen Y, Nepal M, Kim JH, Zhang J, Fei P. TFG-maintaining stability of overlooked FANCD2 confers early DNA-damage response. Aging (Albany NY). 2020 Oct 24; 12 (20):20268-20284
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  14. Wen S, He Y, Wang L, Zhang J, Quan C, Niu Y, Huang H. Aberrant activation of super enhancer and choline metabolism drive antiandrogen therapy resistance in prostate cancer. Oncogene. 2020 Oct; 39 (42):6556-6571 Epub 2020 Sept 11
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  15. Yan Y, Ma J, Wang D, Lin D, Pang X, Wang S, Zhao Y, Shi L, Xue H, Pan Y, Zhang J, Wahlestedt C, Giles FJ, Chen Y, Gleave ME, Collins CC, Ye D, Wang Y, Huang H. The novel BET-CBP/p300 dual inhibitor NEO2734 is active in SPOP mutant and wild-type prostate cancer. EMBO Mol Med. 2019 Nov 7; 11 (11):e10659 Epub 2019 Sept 26
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  16. Zhou LJ, Peng J, Xu YN, Zeng WJ, Zhang J, Wei X, Mai CL, Lin ZJ, Liu Y, Murugan M, Eyo UB, Umpierre AD, Xin WJ, Chen T, Li M, Wang H, Richardson JR, Tan Z, Liu XG, Wu LJ. Microglia Are Indispensable for Synaptic Plasticity in the Spinal Dorsal Horn and Chronic Pain. Cell Rep. 2019 Jun 25; 27 (13):3844-3859.e6
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  17. Steinauer N, Guo C, Huang C, Wong M, Tu Y, Freter CE, Zhang J. Myeloid translocation gene CBFA2T3 directs a relapse gene program and determines patient-specific outcomes in AML. Blood Adv. 2019 May 14; 3 (9):1379-1393
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  18. Zhao Y, Ding L, Wang D, Ye Z, He Y, Ma L, Zhu R, Pan Y, Wu Q, Pang K, Hou X, Weroha SJ, Han C, Coleman R, Coleman I, Karnes RJ, Zhang J, Nelson PS, Wang L, Huang H. EZH2 cooperates with gain-of-function p53 mutants to promote cancer growth and metastasis. EMBO J. 2019 Mar 1; 38 (5) Epub 2019 Feb 05
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  19. Ma L, Yan Y, Bai Y, Yang Y, Pan Y, Gang X, Karnes RJ, Zhang J, Lv Q, Wu Q, Huang H. Overcoming EZH2 Inhibitor Resistance by Taxane in PTEN-Mutated Cancer. Theranostics. 2019; 9 (17):5020-5034 Epub 2019 July 09
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  20. Pan Y, Wang Z, Zhang G, Guo J, Zhu X, Zhou J, Zhang Z, Sun Z, Yang J, Kastin AJ, Pan W, Wu X, Zhang J, Wang X, Wang C, He Y. Schizophrenia Patient Shows a Rare Interleukin 15 Receptor alpha Variant Disrupting Signal Transduction. Curr Mol Med. 2019; 19 (8):560-569
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  21. Rivas AM, Nassar A, Zhang J, Casler JD, Chindris AM, Smallridge R, Bernet V. THYROSEQ((R))V2.0 MOLECULAR TESTING: A COST-EFFECTIVE APPROACH FOR THE EVALUATION OF INDETERMINATE THYROID NODULES. Endocr Pract. 2018 Sep; 24 (9):780-788 Epub 2018 Aug 07
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  22. Acuna A, Berman AG, Damen FW, Meyers BA, Adelsperger AR, Bayer KC, Brindise MC, Bungart B, Kiel AM, Morrison RA, Muskat JC, Wasilczuk KM, Wen Y, Zhang J, Zito P, Goergen CJ. Computational Fluid Dynamics of Vascular Disease in Animal Models. J Biomech Eng. 2018 Aug 1; 140 (8):0808011-08080114
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  23. Yan Y, An J, Yang Y, Wu D, Bai Y, Cao W, Ma L, Chen J, Yu Z, He Y, Jin X, Pan Y, Ma T, Wang S, Hou X, Weroha SJ, Karnes RJ, Zhang J, Westendorf JJ, Wang L, Chen Y, Xu W, Zhu R, Wang D, Huang H. Dual inhibition of AKT-mTOR and AR signaling by targeting HDAC3 in PTEN- or SPOP-mutated prostate cancer. EMBO Mol Med. 2018 Apr; 10(4).
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  24. Che R, Zhang J, Nepal M, Han B, Fei P. Multifaceted Fanconi Anemia Signaling. Trends Genet. 2018 Mar; 34 (3):171-183 Epub 2017 Dec 16
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  25. Yang Y, Bai Y, He Y, Zhao Y, Chen J, Ma L, Pan Y, Hinten M, Zhang J, Karnes RJ, Kohli M, Westendorf JJ, Li B, Zhu R, Huang H, Xu W. PTEN Loss Promotes Intratumoral Androgen Synthesis and Tumor Microenvironment Remodeling via Aberrant Activation of RUNX2 in Castration-Resistant Prostate Cancer. Clin Cancer Res. 2018 Feb 15; 24 (4):834-846 Epub 2017 Nov 22
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  26. Gadhikar MA, Zhang J, Shen L, Rao X, Wang J, Zhao M, Kalu NN, Johnson FM, Byers LA, Heymach J, Hittelman WN, Udayakumar D, Pandita RK, Pandita TK, Pickering CR, Redwood AB, Piwnica-Worms H, Schlacher K, Frederick MJ, Myers JN. CDKN2A/p16 Deletion in Head and Neck Cancer Cells Is Associated with CDK2 Activation, Replication Stress, and Vulnerability to CHK1 Inhibition. Cancer Res. 2018 Feb 1; 78 (3):781-797 Epub 2017 Dec 11
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  27. Ma C, Wang Z, Nepal M, Hokutan K, Zhang J, Yu H, Fei P. DNA methylation at the vicinity of the proximal polyadenylation site in FANCD2 gene involves human malignancy. Cell Cycle 2018; 17 (17):2204-2206 Epub 2018 Sept 14
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  28. Nepal M, Che R, Zhang J, Ma C, Fei P. Fanconi Anemia Signaling and Cancer. Trends Cancer. 2017 Dec; 3 (12):840-856 Epub 2017 Nov 10
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  29. Yang Y, Blee AM, Wang D, An J, Pan Y, Yan Y, Ma T, He Y, Dugdale J, Hou X, Zhang J, Weroha SJ, Zhu WG, Wang YA, DePinho RA, Xu W, Huang H. Loss of FOXO1 Cooperates with TMPRSS2-ERG Overexpression to Promote Prostate Tumorigenesis and Cell Invasion. Cancer Res. 2017 Dec 1; 77 (23):6524-6537 Epub 2017 Oct 06
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  30. Han B, Park HK, Ching T, Panneerselvam J, Wang H, Shen Y, Zhang J, Li L, Che R, Garmire L, Fei P. Human DBR1 modulates the recycling of snRNPs to affect alternative RNA splicing and contributes to the suppression of cancer development. Oncogene. 2017 Sep 21; 36 (38):5382-5391 Epub 2017 May 15
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  31. Zhang P, Wang D, Zhao Y, Ren S, Gao K, Ye Z, Wang S, Pan CW, Zhu Y, Yan Y, Yang Y, Wu D, He Y, Zhang J, Lu D, Liu X, Yu L, Zhao S, Li Y, Lin D, Wang Y, Wang L, Chen Y, Sun Y, Wang C, Huang H. Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT-mTORC1 activation. Nat Med. 2017 Sep; 23 (9):1055-1062 Epub 2017 Aug 14
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  32. Gupta S, Zhang J, Erickson LA. Composite Pheochromocytoma/Paraganglioma-Ganglioneuroma: A Clinicopathologic Study of Eight Cases with Analysis of Succinate Dehydrogenase. Endocr Pathol. 2017 Sep; 28 (3):269-275
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  33. Gupta S, Zhang J, Milosevic D, Mills JR, Grebe SK, Smith SC, Erickson LA. Primary Renal Paragangliomas and Renal Neoplasia Associated with Pheochromocytoma/Paraganglioma: Analysis of von Hippel-Lindau (VHL), Succinate Dehydrogenase (SDHX) and Transmembrane Protein 127 (TMEM127). Endocr Pathol. 2017 Sep; 28 (3):253-268
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  34. Nepal M, Che R, Ma C, Zhang J, Fei P. FANCD2 and DNA Damage. Int J Mol Sci. 2017 Aug 19; 18 (8)
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  35. Pan CW, Jin X, Zhao Y, Pan Y, Yang J, Karnes RJ, Zhang J, Wang L, Huang H. AKT-phosphorylated FOXO1 suppresses ERK activation and chemoresistance by disrupting IQGAP1-MAPK interaction. EMBO J. 2017 Apr 13; 36 (8):995-1010 Epub 2017 Mar 09
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  36. Han B, Shen Y, Zhang P, Jayabal P, Che R, Zhang J, Yu H, Fei P. Overlooked FANCD2 variant encodes a promising, portent tumor suppressor, and alternative polyadenylation contributes to its expression. Oncotarget. 2017 Apr 4; 8 (14):22490-22500
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  37. Yang J, Jin X, Yan Y, Shao Y, Pan Y, Roberts LR, Zhang J, Huang H, Jiang J. Inhibiting histone deacetylases suppresses glucose metabolism and hepatocellular carcinoma growth by restoring FBP1 expression. Sci Rep. 2017 Mar 6; 7:43864 Epub 2017 Mar 06
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  38. Kim JJ, Lee SB, Yi SY, Han SA, Kim SH, Lee JM, Tong SY, Yin P, Gao B, Zhang J, Lou Z. WSB1 overcomes oncogene-induced senescence by targeting ATM for degradation. Cell Res. 2017 Feb; 27 (2):274-293 Epub 2016 Dec 13
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  39. Liu T, Yu J, Deng M, Yin Y, Zhang H, Luo K, Qin B, Li Y, Wu C, Ren T, Han Y, Yin P, Kim J, Lee S, Lin J, Zhang L, Zhang J, Nowsheen S, Wang L, Boughey J, Goetz MP, Yuan J, Lou Z. CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1. Nat Commun. 2017 Jan 9; 8:13923 Epub 2017 Jan 09
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  40. Merten MM, Castro MR, Zhang J, Durski J, Ryder M. Examining the Role of Preoperative Positron Emission Tomography/Computerized Tomography in Combination with Ultrasonography in Discriminating Benign from Malignant Cytologically Indeterminate Thyroid Nodules. Thyroid. 2017 Jan; 27 (1):95-102 Epub 2016 Dec 05
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  41. Steinauer N, Guo C, Zhang J. Emerging Roles of MTG16 in Cell-Fate Control of Hematopoietic Stem Cells and Cancer. Stem Cells Int. 2017; 2017:6301385 Epub 2017 Nov 22
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  42. Gupta S, Zhang J, Rivera M, Erickson LA. Urinary Bladder Paragangliomas: Analysis of Succinate Dehydrogenase and Outcome. Endocr Pathol. 2016 Sep; 27 (3):243-52
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  43. Li J, Guo C, Steinauer N, Zhang J. New insights into transcriptional and leukemogenic mechanisms of AML1-ETO and E2A fusion proteins. Front Biol (Beijing). 2016 Aug; 11 (4):285-304 Epub 2016 Sept 03
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  44. Zhao J, Zhao Y, Wang L, Wang L, Zhang J, Karnes RJ, Kohli M, Wang G, Huang H. Alterations of androgen receptor-regulated enhancer RNAs (eRNAs) contribute to enzalutamide resistance in castration-resistant prostate cancer. Oncotarget. 2016 Jun 21; 7 (25):38551-38565
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  45. Panneerselvam J, Wang H, Zhang J, Che R, Yu H, Fei P. BLM promotes the activation of Fanconi Anemia signaling pathway. Oncotarget. 2016 May 31; 7 (22):32351-61
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  46. Zhao Y, Wang L, Ren S, Wang L, Blackburn PR, McNulty MS, Gao X, Qiao M, Vessella RL, Kohli M, Zhang J, Karnes RJ, Tindall DJ, Kim Y, MacLeod R, Ekker SC, Kang T, Sun Y, Huang H. Activation of P-TEFb by Androgen Receptor-Regulated Enhancer RNAs in Castration-Resistant Prostate Cancer. Cell Rep. 2016 Apr 19; 15 (3):599-610 Epub 2016 Apr 07
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  47. Panneerselvam J, Xie G, Che R, Su M, Zhang J, Jia W, Fei P. Distinct Metabolic Signature of Human Bladder Cancer Cells Carrying an Impaired Fanconi Anemia Tumor-Suppressor Signaling Pathway. J Proteome Res. 2016 Apr 1; 15 (4):1333-41 Epub 2016 Mar 16
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  48. Gang X, Yang Y, Zhong J, Jiang K, Pan Y, Karnes RJ, Zhang J, Xu W, Wang G, Huang H. P300 acetyltransferase regulates fatty acid synthase expression, lipid metabolism and prostate cancer growth. Oncotarget. 2016 Mar 22; 7 (12):15135-49
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  49. Pannala R, Hallberg-Wallace KM, Smith AL, Nassar A, Zhang J, Zarka M, Reynolds JP, Chen L. Endoscopic ultrasound-guided fine needle aspiration cytology of metastatic renal cell carcinoma to the pancreas: A multi-center experience. Cytojournal. 2016; 13:24. Epub 2016 Oct 13.
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  50. Wang D, Ding L, Wang L, Zhao Y, Sun Z, Karnes RJ, Zhang J, Huang H. LncRNA MALAT1 enhances oncogenic activities of EZH2 in castration-resistant prostate cancer. Oncotarget. 2015 Dec 1; 6 (38):41045-55
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  51. Erickson LA, Vrana JA, Theis J, Rivera M, Lloyd RV, McPhail E, Zhang J. Analysis of Amyloid in Medullary Thyroid Carcinoma by Mass Spectrometry-Based Proteomic Analysis. Endocr Pathol. 2015 Dec; 26 (4):291-5
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  52. Barr Fritcher EG, Voss JS, Brankley SM, Campion MB, Jenkins SM, Keeney ME, Henry MR, Kerr SM, Chaiteerakij R, Pestova EV, Clayton AC, Zhang J, Roberts LR, Gores GJ, Halling KC, Kipp BR. An Optimized Set of Fluorescence In Situ Hybridization Probes for Detection of Pancreatobiliary Tract Cancer in Cytology Brush Samples. Gastroenterology. 2015 Dec; 149 (7):1813-1824.e1 Epub 2015 Aug 29
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  53. Kim JJ, Lee SB, Jang J, Yi SY, Kim SH, Han SA, Lee JM, Tong SY, Vincelette ND, Gao B, Yin P, Evans D, Choi DW, Qin B, Liu T, Zhang H, Deng M, Jen J, Zhang J, Wang L, Lou Z. WSB1 promotes tumor metastasis by inducing pVHL degradation. Genes Dev. 2015 Nov 1; 29 (21):2244-57
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  54. Chen L, Nassar A, Kommineni VT, Zarka MA, Zhang J, Faigel D, Nguyen C, Halfdanarson TR, Pannala R. Endoscopic ultrasonography-guided fine-needle aspiration cytology of surgically confirmed cystic pancreatic neuroendocrine tumors: a Mayo Clinic experience. J Am Soc Cytopathol. 2015 Nov - Dec; 4 (6):335-343 Epub 2015 Apr 15
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  55. Lee SB, Kim JJ, Nam HJ, Gao B, Yin P, Qin B, Yi SY, Ham H, Evans D, Kim SH, Zhang J, Deng M, Liu T, Zhang H, Billadeau DD, Wang L, Giaime E, Shen J, Pang YP, Jen J, van Deursen JM, Lou Z. Parkin Regulates Mitosis and Genomic Stability through Cdc20/Cdh1. Mol Cell. 2015 Oct 1; 60 (1):21-34 Epub 2015 Sept 17
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  56. An J, Ren S, Murphy SJ, Dalangood S, Chang C, Pang X, Cui Y, Wang L, Pan Y, Zhang X, Zhu Y, Wang C, Halling GC, Cheng L, Sukov WR, Karnes RJ, Vasmatzis G, Zhang Q, Zhang J, Cheville JC, Yan J, Sun Y, Huang H. Truncated ERG Oncoproteins from TMPRSS2-ERG Fusions Are Resistant to SPOP-Mediated Proteasome Degradation. Mol Cell. 2015 Sep 17; 59 (6):904-16 Epub 2015 Sept 03
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  57. Shen Y, Lee YH, Panneerselvam J, Zhang J, Loo LW, Fei P. Mutated Fanconi anemia pathway in non-Fanconi anemia cancers. Oncotarget. 2015 Aug 21; 6 (24):20396-403
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  58. Zhao W, Xu Q, Yang Y, Tong J, Zhang J, Li Y, Shao Z, Li L. [Preparation and identification of the polyclonal antibody against human insulin-like growth factor 2 mRNA-binding protein 3]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2015 Apr; 31 (4):544-8
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  59. Pan C, An J, Pan Y, Wang L, Zhang J, Qi J, Huang H. MP55-01 Cytoplasmic FOXO1 Negatively Regulates ERK to Overcome TAXOL Resistance in Prostate Cancer. The Journal of Urology. 2015 April; 193(4).
  60. Pinto EM, Chen X, Easton J, Finkelstein D, Liu Z, Pounds S, Rodriguez-Galindo C, Lund TC, Mardis ER, Wilson RK, Boggs K, Yergeau D, Cheng J, Mulder HL, Manne J, Jenkins J, Mastellaro MJ, Figueiredo BC, Dyer MA, Pappo A, Zhang J, Downing JR, Ribeiro RC, Zambetti GP. Genomic landscape of paediatric adrenocortical tumours. Nat Commun. 2015 Mar 6; 6:6302 Epub 2015 Mar 06
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  61. Qin B, Minter-Dykhouse K, Yu J, Zhang J, Liu T, Zhang H, Lee S, Kim J, Wang L, Lou Z. DBC1 functions as a tumor suppressor by regulating p53 stability. Cell Rep. 2015 Mar 3; 10 (8):1324-34 Epub 2015 Feb 26
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  62. Gincul R, Gomez V, Kerr SE, Zhang J, Levy MJ. Endoscopic ultrasound-guided fine-needle aspiration of a pulmonary artery malignant thrombus. Endoscopy. 2015; 47 Suppl 1:E547-9.
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  63. Shen Y, Zhang J, Yu H, Fei P. Advances in the understanding of Fanconi Anemia Complementation Group D2 Protein (FANCD2) in human cancer. Cancer Cell Microenviron. 2015; 2 (4) Epub 2015 Sept 07
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  64. Erickson LA, Highsmith WE Jr, Fei P, Zhang J. Targeting the hypoxia pathway to treat pancreatic cancer. Drug Des Devel Ther. 2015; 9:2029-31 Epub 2015 Apr 08
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  65. Jin L, Lloyd RV, Henry MR, Erickson LA, Sebo TJ, Rumilla KM, Zhang J. The diagnostic utility of combination of HMGA2 and IMP3 qRT-PCR testing in thyroid neoplasms. Appl Immunohistochem Mol Morphol. 2015 Jan; 23 (1):36-43
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  66. Reynolds JP, Voss JS, Kipp BR, Karnes RJ, Nassar A, Clayton AC, Henry MR, Sebo TJ, Zhang J, Halling KC. Comparison of urine cytology and fluorescence in situ hybridization in upper urothelial tract samples. Cancer Cytopathol. 2014 Jun; 122(6):459-67. Epub 2014 Mar 06.
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  67. Erickson LA, Rivera M, Zhang J. Adrenocortical carcinoma: review and update. Adv Anat Pathol. 2014 May; 21(3):151-9.
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  68. Ding L, Chen S, Liu P, Pan Y, Zhong J, Regan KM, Wang L, Yu C, Rizzardi A, Cheng L, Zhang J, Schmechel SC, Cheville JC, Van Deursen J, Tindall DJ, Huang H. CBP loss cooperates with PTEN haploinsufficiency to drive prostate cancer: implications for epigenetic therapy. Cancer Res. 2014 Apr 1; 74 (7):2050-61 Epub 2014 Feb 03
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  69. Zhong J, Ding L, Bohrer LR, Pan Y, Liu P, Zhang J, Sebo TJ, Karnes RJ, Tindall DJ, van Deursen J, Huang H. p300 acetyltransferase regulates androgen receptor degradation and PTEN-deficient prostate tumorigenesis. Cancer Res. 2014 Mar 15; 74 (6):1870-1880 Epub 2014 Jan 30
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  70. Castro MR, Thomas BC, Richards ML, Zhang J, Morris JC. Multiple endocrine neoplasia type 2A due to an exon 8 (G533C) mutation in a large North American kindred. Thyroid. 2013 Dec; 23 (12):1547-52 Epub 2013 July 25
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  71. Pickering A, Zhang J, Panneerselvam J, Fei P. Advances in the understanding of the Fanconi anemia tumor suppressor pathway. Cancer Biol Ther. 2013 Dec; 14 (12):1089-91 Epub 2013 Sept 09
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  72. Pickering A, Panneerselvam J, Zhang J, Zheng J, Zhang Y, Fei P. In vitro FANCD2 monoubiquitination by HHR6 and hRad18. Cell Cycle 2013 Nov 1; 12 (21):3448-9 Epub 2013 Sept 13
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  73. Panneerselvam J, Pickering A, Zhang J, Wang H, Tian H, Zheng J, Fei P. A hidden role of the inactivated FANCD2: upregulating DeltaNp63. Oncotarget. 2013 Sep; 4(9):1416-26.
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  74. Voss JS, Holtegaard LM, Kerr SE, Fritcher EG, Roberts LR, Gores GJ, Zhang J, Highsmith WE, Halling KC, Kipp BR. Molecular profiling of cholangiocarcinoma shows potential for targeted therapy treatment decisions. Hum Pathol. 2013 Jul; 44 (7):1216-22 Epub 2013 Feb 04
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  75. Fu D, Dudimah FD, Zhang J, Pickering A, Paneerselvam J, Palrasu M, Wang H, Fei P. Recruitment of DNA polymerase eta by FANCD2 in the early response to DNA damage. Cell Cycle. 2013 Mar 1; 12(5):803-9. Epub 2013 Feb 06.
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  76. Limburg PJ, Mandrekar SJ, Aubry MC, Ziegler KL, Zhang J, Yi JE, Henry M, Tazelaar HD, Lam S, McWilliams A, Midthun DE, Edell ES, Rickman OB, Mazzone P, Tockman M, Beamis JF, Lamb C, Simoff M, Loprinzi C, Szabo E, Jett J, Cancer Prevention Network. Randomized phase II trial of sulindac for lung cancer chemoprevention. Lung Cancer. 2013 Mar; 79 (3):254-61 Epub 2012 Dec 20
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  77. Kipp BR, Voss JS, Kerr SE, Barr Fritcher EG, Graham RP, Zhang L, Highsmith WE, Zhang J, Roberts LR, Gores GJ, Halling KC. Isocitrate dehydrogenase 1 and 2 mutations in cholangiocarcinoma. Hum Pathol. 2012 Oct; 43 (10):1552-8 Epub 2012 Apr 12
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  78. Ji Y, Nordgren KK, Chai Y, Hebbring SJ, Jenkins GD, Abo RP, Peng Y, Pelleymounter LL, Moon I, Eckloff BW, Chai X, Zhang J, Fridley BL, Yee VC, Wieben ED, Weinshilboum RM. Human liver methionine cycle: MAT1A and GNMT gene resequencing, functional genomics, and hepatic genotype-phenotype correlation. Drug Metab Dispos. 2012 Oct; 40 (10):1984-92 Epub 2012 July 17
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  79. Panneerselvam J, Park HK, Zhang J, Dudimah FD, Zhang P, Wang H, Fei P. FAVL impairment of the Fanconi anemia pathway promotes the development of human bladder cancer. Cell Cycle. 2012 Aug 01; 11(15):2947-55.
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  80. Levy M, Trivedi A, Zhang J, Miles L, Mattis AN, Kim GE, Lassman C, Anders RA, Misdraji J, Yerian LM, Xu H, Dhall D, Wang HL. Expression of glypican-3 in undifferentiated embryonal sarcoma and mesenchymal hamartoma of the liver. Hum Pathol. 2012 May; 43(5):695-701. Epub 2011 Sep 19.
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  81. Levy MJ, Oberg TN, Campion MB, Clayton AC, Halling KC, Henry MR, Kipp BR, Sebo TJ, Zhang J, Enders FT, Clain JE, Gleeson FC, Rajan E, Roberts LR, Topazian MD, Wang KK, Gores GJ. Comparison of methods to detect neoplasia in patients undergoing endoscopic ultrasound-guided fine-needle aspiration. Gastroenterology. 2012 May; 142(5):1112-1121.e2. Epub 2012 Feb 07.
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  82. Liu H, Shi J, Wang HL, Zhang J, Brown RE, Wilkerson M, Lin F. Expression of von Hippel-Lindau gene product (pVHL) and S100P in cystic neoplasms of the pancreas--with an implication for their roles in tumorigenesis. Ann Clin Lab Sci. 2012 Spring; 42(2):109-17.
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  83. Hebbring SJ, Chai Y, Ji Y, Abo RP, Jenkins GD, Fridley B, Zhang J, Eckloff BW, Wieben ED, Weinshilboum RM. Serine hydroxymethyltransferase 1 and 2: gene sequence variation and functional genomic characterization. J Neurochem. 2012 Mar; 120 (6):881-90 Epub 2012 Feb 06
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  84. Mentrikoski MJ, Zhao C, Zhang J, Wang HL, McMahon LA, Yang Q, Li F, Xu H. Metastatic endometrial stromal sarcoma of the lung: importance of immunohistochemical staining, clinical history and imaging studies. Biotech Histochem. 2012 Jan; 87(1):35-9. Epub 2011 Aug 15.
    View PubMed
  85. Park HK, Panneerselvam J, Dudimah FD, Dong G, Sebastian S, Zhang J, Fei P. Wip1 contributes to cell homeostasis maintained by the steady-state level of Wtp53. Cell Cycle. 2011 Aug 01; 10(15):2574-82.
    View PubMed
  86. Jin L, Lloyd RV, Nassar A, Lappinga PJ, Sebo TJ, Swartz K, Seys AR, Erickson-Johnson MR, Roth CW, Evers BR, Oliveira AM, Zhang J. HMGA2 expression analysis in cytological and paraffin-embedded tissue specimens of thyroid tumors by relative quantitative RT-PCR. Diagn Mol Pathol. 2011 Jun; 20(2):71-80.
    View PubMed
  87. Tanaka S, Tanabe A, Aiba M, Hizuka N, Takano K, Zhang J, Young WF Jr. Glucocorticoid- and androgen-secreting black adrenocortical adenomas: unique cause of corticotropin-independent Cushing syndrome. Endocr Pract. 2011 May-Jun; 17(3):e73-8.
    View PubMed
  88. Kipp BR, Fritcher EG, Clayton AC, Gores GJ, Roberts LR, Zhang J, Levy MJ, Halling KC. Comparison of KRAS mutation analysis and FISH for detecting pancreatobiliary tract cancer in cytology specimens collected during endoscopic retrograde cholangiopancreatography. J Mol Diagn. 2010 Nov; 12(6):780-6. Epub 2010 Sep 23.
    View PubMed
  89. Lappinga PJ, Kip NS, Jin L, Lloyd RV, Henry MR, Zhang J, Nassar A. HMGA2 gene expression analysis performed on cytologic smears to distinguish benign from malignant thyroid nodules. Cancer Cytopathol. 2010 Oct 25; 118(5):287-97.
    View PubMed
  90. Park HK, Wang H, Zhang J, Datta S, Fei PW. Convergence of rad6/rad18 and fanconi anemia tumor suppressor pathways upon DNA damage. PLoS ONE. 2010 Oct 13; 5(10).
  91. Campion MB, Kipp BR, Humphrey SK, Zhang J, Clayton AC, Henry MR. Improving cellularity and quality of liquid-based cytology slides processed from pancreatobiliary tract brushings. Diagn Cytopathol. 2010 Sep; 38(9):627-32.
    View PubMed
  92. Zhang J, Zhao D, Park HK, Wang H, Dyer RB, Liu W, Klee GG, McNiven MA, Tindall DJ, Molina JR, Fei P. FAVL elevation in human tumors disrupts Fanconi anemia pathway signaling and promotes genomic instability and tumor growth. J Clin Invest. 2010 May; 120 (5):1524-34 Epub 2010 Apr 19
    View PubMed
  93. Gleeson FC, Kipp BR, Caudill JL, Clain JE, Clayton AC, Halling KC, Henry MR, Rajan E, Topazian MD, Wang KK, Wiersema MJ, Zhang J, Levy MJ. False positive endoscopic ultrasound fine needle aspiration cytology: incidence and risk factors. Gut. 2010 May; 59 (5):586-93
    View PubMed
  94. Kipp B, Clayton AC, Henry MR, Zhang J, Halling KC, Caudill J, Clain J, Rajan E, Topazian M, Wang A, Levy M. Gold Standard Verification of the EUS FNA False Positive and False Suspicious Rates (Mayo Clinic Experience, 1996-2007). Gut. 2010 May; 59(5):586-93.
  95. Aydin H, Zhang J, Samaratunga H, Tan N, Magi-Galluzzi C, Klein E, Jones JS, Zhou M. Ductal adenocarcinoma of the prostate diagnosed on transurethral biopsy or resection is not always indicative of aggressive disease: implications for clinical management. BJU Int. 2010 Feb; 105(4):476-80. Epub 2009 Aug 25.
    View PubMed
  96. Asioli S, Erickson LA, Sebo TJ, Zhang J, Jin L, Thompson GB, Lloyd RV. Papillary thyroid carcinoma with prominent hobnail features: a new aggressive variant of moderately differentiated papillary carcinoma. A clinicopathologic, immunohistochemical, and molecular study of eight cases. Am J Surg Pathol. 2010 Jan; 34 (1):44-52
    View PubMed
  97. Radtke I, Mullighan CG, Ishii M, Su X, Cheng J, Ma J, Ganti R, Cai Z, Goorha S, Pounds SB, Cao X, Obert C, Armstrong J, Zhang J, Song G, Ribeiro RC, Rubnitz JE, Raimondi SC, Shurtleff SA, Downing JR. Genomic analysis reveals few genetic alterations in pediatric acute myeloid leukemia. Proc Natl Acad Sci U S A. 2009 Aug 4; 106 (31):12944-9 Epub 2009 July 27
    View PubMed
  98. Zhang J, Park HK, Sun H, Sun H, Fei P. RNA helicase and colon cancer. Cancer Biol Ther 2008 Oct; 7 (10):1677-8 Epub 2008 Oct 26
    View PubMed
  99. Kipp BR, Tyner HL, Campion MB, Voss JS, Karnes RJ, Sebo TJ, Halling KC, Zhang J. Chromosomal alterations detected by fluorescence in situ hybridization in urothelial carcinoma and rarer histologic variants of bladder cancer. Am J Clin Pathol. 2008 Oct; 130 (4):552-9
    View PubMed
  100. Kipp BR, Halling KC, Campion MB, Wendel AJ, Karnes RJ, Zhang J, Sebo TJ. Assessing the value of reflex fluorescence in situ hybridization testing in the diagnosis of bladder cancer when routine urine cytological examination is equivocal. J Urol. 2008 Apr; 179 (4):1296-301; discussion 1301 Epub 2008 Mar 04
    View PubMed
  101. Lin F, Shi J, Liu H, Zhang J, Zhang PL, Wang HL, Yang XJ, Schuerch C. Immunohistochemical detection of the von Hippel-Lindau gene product (pVHL) in human tissues and tumors: a useful marker for metastatic renal cell carcinoma and clear cell carcinoma of the ovary and uterus. Am J Clin Pathol. 2008 Apr; 129(4):592-605.
    View PubMed
  102. Zhang J, Zhao D, Wang H, Lin CJ, Fei P. FANCD2 monoubiquitination provides a link between the HHR6 and FA-BRCA pathways. Cell Cycle. 2008 Feb 1; 7 (3):407-13 Epub 2007 Oct 11
    View PubMed
  103. Lin F, Shi J, Liu H, Hull ME, Dupree W, Prichard JW, Brown RE, Zhang J, Wang HL, Schuerch C. Diagnostic utility of S100P and von Hippel-Lindau gene product (pVHL) in pancreatic adenocarcinoma-with implication of their roles in early tumorigenesis. Am J Surg Pathol. 2008 Jan; 32(1):78-91.
    View PubMed
  104. Hebbring SJ, Adjei AA, Baer JL, Jenkins GD, Zhang J, Cunningham JM, Schaid DJ, Weinshilboum RM, Thibodeau SN. Human SULT1A1 gene: copy number differences and functional implications. Hum Mol Genet. 2007 Mar 1; 16 (5):463-70 Epub 2006 Dec 22
    View PubMed
  105. Zhang J, Wang X, Lin CJ, Wang X, Couch FJ, Fei P. Altered expression of FANCL confers mitomycin C sensitivity in Calu-6 lung cancer cells. Cancer Biol Ther. 2006 Dec; 5 (12):1632-6 Epub 2006 Dec 05
    View PubMed
  106. Feinberg EC, Larsen FW, Catherino WH, Zhang J, Armstrong AY. Comparison of assisted reproductive technology utilization and outcomes between Caucasian and African American patients in an equal-access-to-care setting. Fertil Steril. 2006 Apr; 85 (4):888-94 Epub 2006 Mar 09
    View PubMed
  107. Zhang J, Ali, SZ. Hepatocyte paraffin 1 immunoexpression in esophageal brush samples. Cancer. 2006 Feb 25; 108(1):73-4.
  108. Zhang J, Martins CR, Fansler ZB, Roemer KL, Kincaid EA, Gustafson KS, Heitjan DF, Clark DP. DNA methylation in anal intraepithelial lesions and anal squamous cell carcinoma. Clin Cancer Res. 2005 Sep 15; 11(18):6544-9.
    View PubMed
  109. Zhang J, Parwani AV, Ali SZ. Hepatocyte paraffin 1 immunoexpression in esophageal brush samples. Cancer. 2005.
  110. Zhang J, Banfic H, Stefano V, Francesca S, Lara T, Rittenhouse SE. A new isoform of phosphoinositide 3-kinase, PI3KC2 , is stimulated via activated integrin in platelets: A source of PtdIns3P. J Biol Chem. 1998 Jun 5; 273(23):14081-4.
    View PubMed
  111. Zhang J, Zhang J, Shattil SJ, Cunningham MC, Rittenhouse SE. Phosphoinositide 3-kinase gamma and p85/phosphoinositide 3-kinase in platelets. Relative activation by thrombin receptor or beta-phorbol myristate acetate and roles in promoting the ligand-binding function of alphaIIbbeta3 integrin. J Biol Chem. 1996 Mar 15; 271 (11):6265-72
    View PubMed
  112. Zhang J, Falck JR, Abrams CS, Zhao W, Rittenhouse SE. Phosphatidylinositol(3,4,5)-trisphosphate stimulates phosphorylation of pleckstrin in human platelets. J Biol Chem. 1995 Sep 29; 270(39):22807-10.
    View PubMed
  113. Zhang J, Rittenhouse SE. Lysophosphatidic acid activates phosphoinositide 3-kinase and phospholipase C in human platelets: inhibitory effects of Wortmannin on phosphoinotide 3-kinase and aggregation. Biochem Biophys Res Commun. 1995 Jun 15; 211(2):484-90.
    View PubMed
  114. Zhang J, Zhang J, Benovic JL, Zhang J, Sugai M, Wetzker R, Gout I, Rittenhouse SE. Sequestration of a G-protein beta gamma subunit or ADP-ribosylation of Rho can inhibit thrombin-induced activation of platelet phosphoinositide 3-kinases. J Biol Chem. 1995 Mar 24; 270 (12):6589-94
    View PubMed
  115. Zhang J, Xu SH, et al. Effects of Sodium Ferulate in preventing pulmonary thromboembolism induced by Arachidonic Acid. Basic and Clinical Medical Sciences. 1993; 13(4):299-304.
  116. Zhang J, Xu SH, et al. Effects of Sodium Ferulate on platelets aggregation and the levels of platelet cGMP. Basic and Clinical Medical Sciences. 1992; 12(4):252.
  117. Zhang J, Xu SH, et al. The animal models and applications of embolic pulmonary artery hypertension. The Chinese Journal of Pathophysiology. 1991; 5(2):129-136.