Publications

1. Schultz DF, Davies BA, Payne JA, Martin CP, Minard AY, Childs BG, Zhang C, Jeganathan KB, Sturmlechner I, White TA, de Bruin A, Harkema L, Chen H, Davies MA, Jachim S, LeBrasseur NK, Piper RC, Li H, Baker DJ, van Deursen J, Billadeau DD, Katzmann DJ. Loss of HD-PTP function results in lipodystrophy, defective cellular signaling and altered lipid homeostasis. J Cell Sci. 2024 Sep 15; 137 (18) Epub 2024 Sept 27
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2. Davies BA, Payne JA, Martin CP, Schultz D, Childs BG, Zhang C, Jeganathan KB, Sturmlechner I, White TA, de Bruin A, Chen H, Davies MA, Jachim S, LeBrasseur NK, Piper RC, Li H, Baker DJ, van Deursen JM, Katzmann DJ. HD-PTP/PTPN23 hypomorphic mice display lipodystrophy BioRxiv. 2022.
   
3. Tseng CC, Piper RC, Katzmann DJ. Bro1 family proteins harmonize cargo sorting with vesicle formation. Bioessays. 2022 Aug; 44 (8):e2100276 Epub 2022 June 30
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4. Pashkova N, Yu L, Schnicker NJ, Tseng CC, Gakhar L, Katzmann DJ, Piper RC. Interactions of ubiquitin and CHMP5 with the V domain of HD-PTP reveals role for regulation of Vps4 ATPase. Mol Biol Cell. 2021 Dec 1; 32 (22):ar42 Epub 2021 Sept 29
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5. Tseng CC, Dean S, Davies BA, Azmi IF, Pashkova N, Payne JA, Staffenhagen J, West M, Piper RC, Odorizzi G, Katzmann DJ. Bro1 stimulates Vps4 to promote intralumenal vesicle formation during multivesicular body biogenesis. J Cell Biol. 2021 Aug 2; 220 (8) Epub 2021 June 23
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6. Chen C, Xu Q, Zhang Y, Davies BA, Huang Y, Katzmann DJ, Harris PC, Hu J, Ling K. Ciliopathy protein HYLS1 coordinates the biogenesis and signaling of primary cilia by activating the ciliary lipid kinase PIPKIgamma. Sci Adv. 2021 Jun; 7 (26) Epub 2021 June 23
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7. Davies BA, Morton LO, Jefferson JR, Rozeveld CN, Doskey LC, LaRusso NF, Katzmann DJ. Polarized human cholangiocytes release distinct populations of apical and basolateral small extracellular vesicles. Mol Biol Cell. 2020 Oct 15; 31 (22):2463-2474 Epub 2020 Aug 26
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8. Limzerwala JF, Jeganathan KB, Kloeber JA, Davies BA, Zhang C, Sturmlechner I, Zhong J, Fierro Velasco R, Fields AP, Yuan Y, Baker DJ, Zhou D, Li H, Katzmann DJ, van Deursen JM. FoxM1 insufficiency hyperactivates Ect2-RhoA-mDia1 signaling to drive cancer. Nat Cancer. 2020 Oct; 1 (10):1010-1024 Epub 2020 Oct 12
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9. Aziz K, Sieben CJ, Jeganathan KB, Hamada M, Davies BA, Velasco ROF, Rahman N, Katzmann DJ, van Deursen JM. Mosaic-variegated aneuploidy syndrome mutation or haploinsufficiency in Cep57 impairs tumor suppression. J Clin Invest. 2018 Aug 1; 128 (8):3517-3534 Epub 2018 July 23
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10. Natesampillai S, Cummins NW, Nie Z, Sampath R, Baker JV, Henry K, Pinzone M, O'Doherty U, Polley EC, Bren GD, Katzmann DJ, Badley AD. HIV Protease-Generated Casp8p41, When Bound and Inactivated by Bcl2, Is Degraded by the Proteasome. J Virol. 2018 Jul 1; 92 (13) Epub 2018 June 13
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11. Nie Z, Aboulnasr F, Natesampillai S, Burke SP, Krogman A, Bren GD, Chung TDY, Anderson JR, Smart MK, Katzmann DJ, Rajagopalan G, Cummins NW, Badley AD. Both HIV-Infected and Uninfected Cells Express TRAILshort, Which Confers TRAIL Resistance upon Bystander Cells within the Microenvironment. J Immunol. 2018 Feb 1; 200 (3):1110-1123 Epub 2017 Dec 20
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12. Kanakkanthara A, Jeganathan KB, Limzerwala JF, Baker DJ, Hamada M, Nam HJ, van Deursen WH, Hamada N, Naylor RM, Becker NA, Davies BA, van Ree JH, Mer G, Shapiro VS, Maher LJ 3rd, Katzmann DJ, van Deursen JM. Cyclin A2 is an RNA binding protein that controls Mre11 mRNA translation. Science. 2016 Sep 30; 353 (6307):1549-1552
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13. Tan J, Davies BA, Payne JA, Benson LM, Katzmann DJ. Conformational Changes in the Endosomal Sorting Complex Required for the Transport III Subunit Ist1 Lead to Distinct Modes of ATPase Vps4 Regulation. J Biol Chem. 2015 Dec 11; 290 (50):30053-65 Epub 2015 Oct 29
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14. MacDonald C, Payne JA, Aboian M, Smith W, Katzmann DJ, Piper RC. A family of tetraspans organizes cargo for sorting into multivesicular bodies. Dev Cell. 2015 May 4; 33 (3):328-42
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15. MacDonald C, Stamnes MA, Katzmann DJ, Piper RC. Tetraspan cargo adaptors usher GPI-anchored proteins into multivesicular bodies. Cell Cycle. 2015; 14 (23):3673-8
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16. Davies BA, Norgan AP, Payne JA, Schulz ME, Nichols MD, Tan JA, Xu Z, Katzmann DJ. Vps4 stimulatory element of the cofactor Vta1 contacts the ATPase Vps4 alpha7 and alpha9 to stimulate ATP hydrolysis. J Biol Chem. 2014 Oct 10; 289 (41):28707-18 Epub 2014 Aug 27
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17. Sainski AM, Dai H, Natesampillai S, Pang YP, Bren GD, Cummins NW, Correia C, Meng XW, Tarara JE, Ramirez-Alvarado M, Katzmann DJ, Ochsenbauer C, Kappes JC, Kaufmann SH, Badley AD. Casp8p41 generated by HIV protease kills CD4 T cells through direct Bak activation. J Cell Biol. 2014 Sep 29; 206(7):867-76. Epub 2014 Sep 22.
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18. Shestakova A, Curtiss M, Davies BA, Katzmann DJ, Babst M. The linker region plays a regulatory role in assembly and activity of the Vps4 AAA ATPase. J Biol Chem. 2013 Sep 13; 288(37):26810-9. Epub 2013 Aug 02.
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19. Norgan AP, Davies BA, Azmi IF, Schroeder AS, Payne JA, Lynch GM, Xu Z, Katzmann DJ. Relief of autoinhibition enhances Vta1 activation of Vps4 via the Vps4 stimulatory element. J Biol Chem. 2013 Sep 6; 288 (36):26147-26156 Epub 2013 July 23
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20. Norgan AP, Lee JR, Oestreich AJ, Payne JA, Krueger EW, Katzmann DJ. ESCRT-independent budding of HIV-1 gag virus-like particles from Saccharomyces cerevisiae spheroplasts. PLoS One. 2012; 7 (12):e52603 Epub 2012 Dec 21
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21. Babst M, Davies BA, Katzmann DJ. Regulation of Vps4 during MVB sorting and cytokinesis. Traffic. 2011 Oct; 12(10):1298-305. Epub 2011 Jul 07.
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22. Wemmer M, Azmi I, West M, Davies B, Katzmann D, Odorizzi G. Bro1 binding to Snf7 regulates ESCRT-III membrane scission activity in yeast. J Cell Biol. 2011 Jan 24; 192(2):295-306.
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23. Norgan AP, Coffman PK, Kocher JP, Katzmann DJ, Sosa CP. Multilevel Parallelization of AutoDock 4.2. J Cheminform. 2011; 3(1):12. Epub 2011 Apr 28.
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24. Davies BA, Azmi IF, Payne J, Shestakova A, Horazdovsky BF, Babst M, Katzmann DJ. Coordination of substrate binding and ATP hydrolysis in Vps4-mediated ESCRT-III disassembly. Mol Biol Cell. 2010 Oct 1; 21 (19):3396-408 Epub 2010 Aug 11
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25. Shestakova A, Hanono A, Drosner S, Curtiss M, Davies BA, Katzmann DJ, Babst M. Assembly of the AAA ATPase Vps4 on ESCRT-III. Mol Biol Cell. 2010 Mar 15; 21(6):1059-71. Epub 2010 Jan 28.
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26. Lee JR, Oestreich AJ, Payne JA, Gunawan MS, Norgan AP, Katzmann DJ. The HECT domain of the ubiquitin ligase Rsp5 contributes to substrate recognition. J Biol Chem. 2009 Nov 13; 284 (46):32126-37 Epub 2009 Sept 10
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27. Xiao J, Chen XW, Davies BA, Saltiel AR, Katzmann DJ, Xu Z. Structural basis of Ist1 function and Ist1-Did2 interaction in the multivesicular body pathway and cytokinesis. Mol Biol Cell. 2009 Aug; 20(15):3514-24. Epub 2009 May 28.
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28. Shields SB, Oestreich AJ, Winistorfer S, Nguyen D, Payne JA, Katzmann DJ, Piper R. ESCRT ubiquitin-binding domains function cooperatively during MVB cargo sorting. J Cell Biol. 2009 Apr 20; 185(2):213-24.
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29. Davies BA, Lee JR, Oestreich AJ, Katzmann DJ. Membrane protein targeting to the MVB/lysosome. Chem Rev. 2009 Apr; 109 (4):1575-86
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30. Davies BA, Azmi IF, Katzmann DJ. Regulation of Vps4 ATPase activity by ESCRT-III. Biochem Soc Trans. 2009 Feb; 37 (Pt 1):143-5
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31. Strochlic TI, Schmiedekamp BC, Lee J, Katzmann DJ, Burd CG. Opposing activities of the Snx3-retromer complex and ESCRT proteins mediate regulated cargo sorting at a common endosome. Mol Biol Cell. 2008 Nov; 19(11):4694-706. Epub 2008 Sep 03.
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32. Xiao J, Xia H, Zhou J, Azmi IF, Davies BA, Katzmann DJ, Xu Z. Structural basis of Vta1 function in the multivesicular body sorting pathway. Dev Cell. 2008 Jan; 14(1):37-49.
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33. Azmi IF, Davies BA, Xiao J, Babst M, Xu Z, Katzmann DJ. ESCRT-III family members stimulate Vps4 ATPase activity directly or via Vta1. Dev Cell. 2008 Jan; 14(1):50-61.
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34. Oestreich AJ, Davies BA, Payne JA, Katzmann DJ. Mvb12 is a novel member of ESCRT-I involved in cargo selection by the multivesicular body pathway. Mol Biol Cell. 2007 Feb; 18 (2):646-57 Epub 2006 Dec 06
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35. Oestreich AJ, Aboian M, Lee J, Azmi I, Payne J, Issaka R, Davies BA, Katzmann DJ. Characterization of multiple multivesicular body sorting determinants within Sna3: a role for the ubiquitin ligase Rsp5. Mol Biol Cell. 2007 Feb; 18 (2):707-20 Epub 2006 Dec 20
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36. Piper RC, Katzmann DJ. Biogenesis and function of multivesicular bodies. Annu Rev Cell Dev Biol. 2007; 23:519-47.
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37. Katzmann DJ. No ESCRT to the melanosome: MVB sorting without ubiquitin. Dev Cell. 2006 Mar; 10(3):278-80.
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38. Azmi I, Davies B, Dimaano C, Payne J, Eckert D, Babst M, Katzmann DJ. Recycling of ESCRTs by the AAA-ATPase Vps4 is regulated by a conserved VSL region in Vta1. J Cell Biol. 2006 Feb 27; 172 (5):705-17
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39. Huang S, Zhou H, Katzmann D, Hochstrasser M, Atanasova E, Zhang Z. Rtt106p is a histone chaperone involved in heterochromatin-mediated silencing. Proc Natl Acad Sci U S A. 2005 Sep 20; 102 (38):13410-5 Epub 2005 Sept 12
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40. Katzmann DJ, Wendland B. Analysis of ubiquitin-dependent protein sorting within the endocytic pathway in Saccharomyces cerevisiae. Methods Enzymol. 2005; 399:192-211.
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41. Katzmann DJ, Sarkar S, Chu T, Audhya A, Emr SD. Multivesicular body sorting: ubiquitin ligase Rsp5 is required for the modification and sorting of carboxypeptidase S. Mol Biol Cell. 2004 Feb; 15(2):468-80.
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42. Katzmann DJ, Stefan CJ, Babst M, Emr SD. Vps27 recruits ESCRT machinery to endosomes during MVB sorting. J Cell Biol. 2003 Aug 4; 162(3):413-23.
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43. Davies BA, Topp JD, Sfeir AJ, Katzmann DJ, Carney DS, Tall GG, Friedberg AS, Deng L, Chen Z, Horazdovsky BF. Vps9p CUE domain ubiquitin binding is required for efficient endocytic protein traffic. J Biol Chem. 2003 May 30; 278 (22):19826-33 Epub 2003 Mar 24
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44. Odorizzi G, Katzmann DJ, Babst M, Audhya A, Emr SD. Bro1 is an endosome-associated protein that functions in the MVB pathway in Saccharomyces cerevisiae. J Cell Sci. 2003 May 15; 116(Pt 10):1893-903.
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45. Katzmann DJ, Odorizzi G, Emr SD. Receptor downregulation and multivesicular-body sorting. Nat Rev Mol Cell Biol. 2002 Dec; 3(12):893-905.
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46. Babst M, Katzmann DJ, Snyder WB, Wendland B, Emr SD. Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body. Dev Cell. 2002 Aug; 3(2):283-9.
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47. Babst M, Katzmann DJ, Estepa-Sabal EJ, Meerloo T, Emr SD. Escrt-III: an endosome-associated hetero oligomeric protein complex required for mvb sorting. Dev Cell. 2002 Aug; 3(2):271-82.
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48. Shih SC, Katzmann DJ, Schnell JD, Sutanto M, Emr SD, Hicke L. Epsins and Vps27p/Hrs contain ubiquitin-binding domains that function in receptor endocytosis. Nat Cell Biol. 2002 May; 4(5):389-93.
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49. Katzmann DJ, Babst M, Emr SD. Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I. Cell. 2001 Jul 27; 106(2):145-55.
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50. Darsow T, Katzmann DJ, Cowles CR, Emr SD. Vps41p function in the alkaline phosphatase pathway requires homo-oligomerization and interaction with AP-3 through two distinct domains. Mol Biol Cell. 2001 Jan; 12(1):37-51.
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51. Rehling P, Darsow T, Katzmann DJ, Emr SD. Formation of AP-3 transport intermediates requires Vps41 function. Nat Cell Biol. 1999 Oct; 1(6):346-53.
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52. Katzmann DJ, Epping EA, Moye-Rowley WS. Mutational disruption of plasma membrane trafficking of Saccharomyces cerevisiae Yor1p, a homologue of mammalian multi drug resistance protein. Mol Cell Biol. 1999 Apr; 19(4):2998-3009.
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53. Hallstrom TC, Katzmann DJ, Torres RJ, Sharp WJ, Moye-Rowley WS. Regulation of transcription factor Pdr1p function by an Hsp70 protein in Saccharomyces cerevisiae. Mol Cell Biol. 1998 Mar; 18(3):1147-55.
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54. Katzmann DJ, Hallstrom TC, Mahe Y, Moye-Rowley WS. Multiple Pdr1p/Pdr3p binding sites are essential for normal expression of the ATP binding cassette transporter protein-encoding gene PDR5. J Biol Chem. 1996 Sep 20; 271(38):23049-54.
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55. Katzmann DJ, Hallstrom TC, Voet M, Wysock W, Golin J, Volckaert G, Moye-Rowley WS. Expression of an ATP-binding cassette transporter-encoding gene (YOR1) is required for oligomycin resistance in Saccharomyces cerevisiae. Mol Cell Biol. 1995 Dec; 15(12):6875-83.
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56. McGuire T, Caravajal E, Katzmann DJ, Wagner M, Moye-Rowley WS, Goffeau A, Golin J. Analysis of second site mutations that suppress the multiple drug resistance phenotype of the yeast PDR1-7 allele. Gene. 1995; 167:151-5.
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57. Katzmann DJ, Burnett PE, Golin J, Mahe Y, Moye-Rowley WS. Transcriptional control of the yeast PDR5 gene by the PDR3 gene product. Mol Cell Biol. 1994 Jul; 14(7):4653-61.
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