The Device Development and Experimental Therapeutics Laboratory invests in numerous clinical trials in support of several areas of research.
- Brain machine interface. Dr. Van Gompel's lab has led the country in developing novel approaches for stimulation, including posterior approach anterior nucleus deep brain stimulation (DBS) and chronic subthreshold stimulation for epilepsy. The lab also has focused on the hardware and biomarkers associated with stimulation of the brain. This research has prompted the development of companies such as Cadence Neuroscience and NeuroOne.
- Minimally invasive cortical surgery. Currently the lab is seeking a Food and Drug Administration investigational device exemption for a device adding in access for minimally invasive cortical surgery assisted with a flexible endoscope. Dr. Van Gompel and his colleagues continue to pursue human and animal studies to develop this surgical technique.
- Pituitary outcome research. The lab has focused on novel imaging techniques, such as magnetic resonance elastography, to understand tumor consistency. Dr. Van Gompel's group also follows continued analyses of patient series to understand pituitary tumor surgery better. Due to the high volume of pituitary tumor surgery at Mayo Clinic and people with unique syndromes, much can still be learned.
- Skull base tumor research. Mayo Clinic experiences many referrals of skull base meningiomas, esthesioneuroblastomas and chordomas. These cases allow us to continue contributing important research in these tumor fields that impacts patient outcomes.
- Education. The lab also is interested in novel simulation, 3D printing and education techniques to assist the next generation of leaders and surgeons.
Hematoxylin-eosin stain of esthesioneuroblastoma
Hematoxylin-eosin stain of chord