The research interests of Ryan J. Uitti, M.D., include delineation of the longitudinal progression of all movement disorders. He has established a comprehensive longitudinal database, employing validated examination ratings in more than 10,000 patient visits over 20 years. In particular, Dr. Uitti's work with Parkinson's disease focuses on asymmetry of motor findings and identifying factors predictive for specific longitudinal outcomes. Dr. Uitti's research team is also studying value of care being provided for patients with chronic movement disorders, taking into account expected outcomes and cost of care over time.
Additional research topics include surgical treatment and outcome measures for Parkinson's disease, essential tremor and dystonia. Dr. Uitti also carries out clinical trials with medications and surgery for patients with movement disorders.
- Surgical trials for Parkinson's disease. Trials aim to improve movement abilities and maintain cognitive function for patients with Parkinson's disease.
- Health care delivery. Studies delineate outcomes associated with specific medication use in Parkinson's disease.
Significance to patient care
Dr. Uitti's research is aimed at identifying underlying causes for common conditions such as Parkinson's disease, essential tremor and dystonia; the development of rationale therapy through collection of clinical data over time; and collaborations with Mayo investigators evaluating genetic, molecular biological and pathological specimens. Through this research, he aims to improve treatment with new therapeutic trials and improve patients' quality of life by objectively measuring patient-centered outcomes.
- Chair, international working group developing outcome measure set for Parkinson's disease, International Consortium for Health Outcomes Measurement, 2013-present
- Member, editorial board, Parkinsonism & Related Disorders journal, 2012-present
- Associate editor handling all movement disorder submissions, Neurology journal, 2006-present
- Secretary, executive board, International Association of Parkinsonism and Related Disorders, 2009-2013