Rochester, Minnesota


Taner.timucin@mayo.edu Clinical Profile


Timucin Taner, M.D., Ph.D., has a clinical practice focused on liver transplantation, and conducts laboratory research aimed primarily at understanding the interaction between the transplanted liver and the recipient's immune responses. The immunobiology of the liver transplant differs significantly from that of other solid organ transplants, as liver allografts are, overall, less prone to rejection. Furthermore, the transplanted liver appears to provide immunoprotection to other simultaneously transplanted solid organs from the same donor. By investigating clinical outcomes and histological and molecular markers, Dr. Taner has demonstrated that kidney allografts that have been transplanted simultaneously with a liver incur less immune injury over the long term. His laboratory is investigating the details of this phenomenon.

Focus areas

  • Liver transplant rejection. Investigating the mechanisms through which liver transplant rejection occurs, particularly by recipients' antibodies against donor antigens (antibody-mediated rejection of the liver) is a focus of Dr. Taner's research.
  • Protective effect of liver transplant on other simultaneously transplanted organs. Dr. Taner facilitates ongoing investigation to unravel the mechanisms underlying the protective impact of the liver transplant, including histologic, cellular and genetic studies.
  • Cell-based therapy to decrease organ rejection. Dr. Taner is a primary investigator at Mayo Clinic in several trials of cell-based therapy in liver transplant recipients to decrease organ rejection, and to limit the recipients' exposure to immunosuppressive medications.

Significance to patient care

Dr. Taner's work will yield a better understanding of the unique immune responses that are brought about by a liver transplant, and help clinicians tailor the recipient's' immunosuppression medication to reduce the potential side effects. In addition, by detecting the mechanisms underlying the protective impact of the transplanted liver, discovery of new therapeutic approaches to achieve stable, long-term hyporesponsiveness to organ allografts other than the liver will be possible, and will improve the post-transplant care of many patients.


Primary Appointment

  1. Consultant, Division of Transplantation Surgery, Department of Surgery

Joint Appointment

  1. Consultant, Department of Immunology

Administrative Appointment

  1. Chair, Division of Transplantation Surgery, Department of Surgery

Academic Rank

  1. Professor of Surgery


  1. Abdominal Transplant Surgery Fellowship, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  2. General Surgery Residency Program, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  3. PhD Department of Immunology, University of Pittsburgh School of Medicinel
  4. MD Hacettepe University School of Medicine, Ankara, Turkey

Clinical Studies

Learn about clinical trials that address specific scientific questions about human health and disease.

See my studies.

Explore all research studies at Mayo Clinic.


See the peer-reviewed findings I have published as a result of my research.

Review publications.

Mayo Clinic Footer