Rochester, Minnesota


Starr.Matthew2@mayo.edu Clinical Profile


The current research interests of Matthew R. Starr, M.D., center around improving patient outcomes within ophthalmology and vitreoretinal surgery. A specific focus is on the optimization of opioids following ophthalmic surgery. Additionally, Dr. Starr is analyzing outcomes following vitreoretinal surgery, as well as innovating new techniques for the management of dislocated intraocular lenses and patients with aphakia.

Currently, Dr. Starr is the principal investigator of numerous clinical trials evaluating the management of both exudative and nonexudative age-related macular degeneration. His studies are looking to advance the care of these patients as current technology evolves.

Focus areas

  • Patient safety and quality improvement. Dr. Starr uses a lean thinking approach to improve patient outcomes.
  • Outcomes following vitreoretinal surgery. Dr. Starr is studying macular hole repair, retinal detachment surgery and epiretinal membrane removal. He is keenly interested in improving outcomes following the use of secondary intraocular lenses.
  • Addressing limitations of care in patients with geographic atrophy. These are due to age-related macular degeneration.

Significance to patient care

Improving outcomes for secondary lenses will allow patients, who have had a complication with cataract surgery or insufficient capsular support, to safely and effectively undergo intraocular lens placement with improvement in vision. Additionally, the work being done on age-related macular degeneration possibly will help many patients without any current treatment to halt vision loss and hopefully one day to improve vision.

Professional highlights

  • Editor, Ocular Trauma Section, EyeWiki, 2023-present.
  • Assistant editor, RETINA Journal Podcast, 2022-present.
  • Assistant editor, RETINA Roundup, 2021-present.


Primary Appointment

  1. Senior Associate Consultant, Department of Ophthalmology

Academic Rank

  1. Assistant Professor of Ophthalmology


  1. Fellow - Vitreoretinal Surgery Wills Eye Hospital
  2. Resident Ophthalmology, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  3. Intern Internal Medicine, Mayo Clinic Graduate School of Medicine
  4. MD School of Medicine, Saint Louis University

Clinical Studies

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