Rochester, Minnesota


Shen.Wei@mayo.edu Clinical Profile


Wei Shen, Ph. D., is a Mayo Clinic researcher whose areas of focus include hereditary cancer predisposition syndromes and rare diseases. He co-leads the hereditary oncology subdiscipline in the Department of Laboratory Medicine and Pathology. As the associate director of Mayo Clinic's Clinical Genome Sequencing Laboratory, Dr. Shen is also interested in implementing advanced sequencing technologies and bioinformatics pipelines to improve patient care.

Focus areas

  • Hereditary cancer predisposition syndromes
  • Rare disease diagnosis using genome sequencing
  • Novel sequencing technologies and bioinformatics algorithms

Significance to patient care

Dr. Shen's research aims to enhance the understanding of genetic predisposition to cancer and improve genetic testing in patients with cancer and rare diseases.


Primary Appointment

  1. Consultant, Division of Laboratory Genetics and Genomics, Department of Laboratory Medicine and Pathology

Joint Appointment

  1. Consultant, Department of Clinical Genomics

Academic Rank

  1. Assistant Professor of Laboratory Medicine and Pathology


  1. Fellowship - Clinical Cytogenetics and Genomics University of Utah School of Medicine
  2. Fellowship - Clinical Molecular Genetics and Genomics University of Utah School of Medicine
  3. Ph.D. - Genetics University of Wisconsin-Madison
  4. BS - Biological Sciences Fudan University

Clinical Studies

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