Rochester, Minnesota




Matthew L. Senjem, M.S., is a senior member of the programming staff of the Aging and Dementia Imaging Laboratory, headed by Clifford R. Jack Jr., M.D. Senjem's primary research is focused on developing software pipelines for automated processing of MRI and positron emission tomography (PET) imaging to support research on Alzheimer's disease and other disorders of the brain.

As a member of Dr. Jack's lab, Senjem supports research efforts involving collaborations with neurologists such as Bradley F. Boeve, M.D., Ronald C. Petersen, M.D., Ph.D., David S. Knopman, M.D., and Keith A. Josephs, M.D., as well as nuclear medicine researchers Val Lowe, M.D., and Bradley J. Kemp, Ph.D.

Focus areas

  • Brain imaging analysis. Techniques employed include automated processing of MRI, PET and amyloid PET images of the brain.
  • Aging and dementia aging. As a member of Dr. Jack's team, Senjem focuses his research on developing image analysis methods to study cognitive aging, Alzheimer's disease and dementia.

Significance to patient care

With brain imaging, it is possible to ascertain pathological processes in living patients. Senjem contributes vital software development to Dr. Jack's laboratory, which uses brain imaging to understand the pathological basis for cognitive aging and dementia.


Academic Rank

  1. Assistant Professor of Radiology

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