Rochester, Minnesota


The research focus of W. Frederick Schwenk II, M.D., is glucose and protein metabolism in children and adults.

Through the use of radioactive and stable, isotopically labeled tracers to define metabolic pathways, information about the substrate and hormonal control of metabolism in the fed and fasted state can be obtained. Dr. Schwenk's research has included pivotal studies on the control of liver glycogen metabolism in normal adults, and studies of children with glycogen storage disease and growth hormone deficiency.

Focus areas

  • Substrate and hormonal control of liver glycogen metabolism
  • Whole-body measurement of protein and glucose turnover in normal individuals and in patients with type 1 diabetes

Significance to patient care

Understanding of the factors that control utilization of sugar and protein in the body can lead to improved therapy in a variety of disease states, including children with low blood sugars, children with glycogen storage disease, and children and adults with diabetes.

Professional highlights

  • Chair, Fellow selection committee, American Society for Parenteral and Enteral Nutrition, 2012-2016
  • Chair, Rhoads Research Foundation, 2009-2011


Administrative Appointment

  1. Emeritus, Department of Pediatric and Adolescent Medicine

Academic Rank

  1. Professor of Pediatrics


  1. Fellow - Pediatric Endocrinology Mayo Graduate School of Medicine, Mayo Clinic College of Medicine
  2. Resident Pediatric Endocrinology, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  3. Resident - Pediatrics Mayo Graduate School of Medicine, Mayo Clinic College of Medicine
  4. MD, CM McGill University
  5. Chemistry Stanford University
  6. BA - Chemistry. Includes 6 months of study at the Friedrich-Alexander Universitat, Erlangen, Germany Kalamazoo College

Clinical Studies

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