David J. Sas, D.O., M.P.H., studies pediatric kidney stones (nephrolithiasis). His research involves children with so-called idiopathic kidney stone disease as well as children with very rare disorders like primary hyperoxaluria, Dent disease and cystinuria. Dr. Sas is also studying the impact of variations in urinary microbiome in different settings of health and disease.
- Collaborative Research on Children With Kidney Stones (CROCKS). This is a longitudinal, prospective, multicenter registry to collect data on children with nephrolithiasis to advance the fund of knowledge in the field.
- Rare Kidney Stone Consortium. This consortium facilitates cooperative exchange of information and resources among investigators, clinicians, patients and researchers to improve care and outcomes for patients with rare stone diseases.
Significance to patient care
Kidney stones are painful and costly, and are associated with increased risks of chronic kidney disease and hypertension. The incidence of kidney stones in children is rising, though the reasons for this increase are unclear. Dr. Sas is leading a team of investigators at multiple pediatric hospitals around the country in collaborative research. Their goal is to make discoveries related to the increasing incidence of kidney stones in children to improve strategies for prevention and treatment.