Rochester, Minnesota


Routman.David@mayo.edu Clinical Profile


David M. Routman, M.D.'s research aims to personalize radiation oncology treatment across multiple malignancies by translating science and technology into clinical application. He is co-founder of Mayo Clinic's Radiation Oncology Informatics Laboratory with a specialized focus on using advances in data science and technology to improve the quality of care while minimizing toxicity. Dr. Routman focuses on patient-reported outcomes, wearable technologies, novel biomarkers, and radiation therapy advances including proton therapy and automation.

Focus areas

  • Head and neck malignancies
  • Central nervous malignancies
  • Proton therapy
  • Remote patient monitoring
  • Patient-reported outcomes
  • Cancer biomarkers
  • Advanced treatment planning

Significance to patient care

By translating biomarkers and automated and predictive tools into clinical practice, Dr. Routman's goal is to design workflows that provide the highest quality, least intensive and individually most appropriate treatment to each person.

Professional highlights

  • Member, NRG Translational Science Committee, 2022-present
  • Co-Chair, Radiation Oncology IT Governance, Mayo Clinic, 2021-present
  • Co-Investigator, Observational Study to Validate Circulating HPVDNA and Prognostic Genomic Biomarkers for Diagnosis and Treatment of HPV-Associated OPSCC, National Institute of Dental and Craniofacial Research, 2020-2025
  • Individual Top-Performing Provider Patient Experience Award, Press Ganey, 2020
  • Roentgen Resident/Fellow Research Award, Radiological Society of North America, 2020
  • Research Grant Award, 5th District Eagles Cancer Telethon, Rochester, Minnesota, 2019-2021
  • Late-breaking abstract selected for Best of ASTRO, American Society for Radiation Oncology, Chicago, Illinois, 2019
  • Outstanding Abstract Travel Award, American College of Radiation Oncology, Fort Lauderdale, Florida, 2018
  • Small Grants Award, Radiation Oncology Research Executive Committee, Mayo Clinic Comprehensive Cancer Center, Rochester, Minnesota, 2018
  • Honor Society, Alpha Omega Alpha Honor Medical Society, 2015


Primary Appointment

  1. Senior Associate Consultant, Department of Radiation Oncology

Academic Rank

  1. Assistant Professor of Radiation Oncology


  1. Residency Radiation Oncology Residency Program, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  2. Resident Radiation Oncology, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  3. Internship - Preliminary Medicine Kaiser Permanente
  4. Doctorate of Medicine Keck School of Medicine, University of Southern California
  5. BA - Molecular and Cell Biology Psychology University of California Berkeley

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