Brain tumor, breast cancer, colon cancer, congenital heart disease, heart arrhythmia. See more conditions.
Research in the laboratory of Kah Whye Peng, Ph.D., is aimed at developing novel therapeutics based on replication-competent viruses for cancer therapy, focusing on ovarian cancer and multiple myeloma.
Dr. Peng's team is currently working on the oncolytic measles virus (Edmonston strain) and vesicular stomatitis virus (Indiana strain). These viruses are tumor selective and have promising anti-tumor activity.
The lab's expertise is in translation of these novel therapeutics into clinical practice, and two of its recombinant measles viruses — genetically modified to express reporter genes for noninvasive monitoring of viral gene expression (MV-CEA and MV-NIS) — have recently completed clinical testing.
The long-term goal of Dr. Peng's laboratory is to develop and test novel anti-cancer therapies for application in clinical settings.
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