Rochester, Minnesota




Hilal Maradit Kremers, M.D., studies the epidemiology and outcomes of musculoskeletal diseases, injuries and procedures, such as hip and knee replacements.

Dr. Maradit Kremers mainly uses clinical information collected during routine medical care, typically using the resources of the Mayo Clinic Total Joint Registry and the Rochester Epidemiology Project. The data collected from these data sources are analyzed using epidemiological or statistical techniques.

The long-term goal of Dr. Maradit Kremers' research is to improve outcomes for patients with musculoskeletal conditions through improved understanding of common risk factors as well as safe and effective management strategies.

Dr. Maradit Kremers also teaches and mentors in pharmacoepidemiology. She facilitated the integration of the historical electronic prescription records into the Rochester Epidemiology Project, which is a unique medical records-linkage system in the U.S. This effort enhanced the infrastructure for studies on the risks, benefits, effectiveness and economic impact of prescription drug use.

Focus areas

  • What are the determinants of clinical outcomes in total joint arthroplasty? Using the resources of the Mayo Clinic Total Joint Registry, Dr. Maradit Kremers examines prostheses and patient characteristics associated with better or worse outcomes in total knee and hip replacement patients.
  • What are the drivers of direct medical costs in total joint arthroplasty? Dr. Maradit Kremers examines how clinical heterogeneity and comorbidities affect health care utilization and cost of care in total knee and hip replacement patients.
  • What are the causes of cardiovascular disease in rheumatoid arthritis and psoriasis? Dr. Maradit Kremers has contributed extensively to the understanding of the magnitude and determinants of cardiovascular disease and the role of disease-modifying therapy on cardiovascular outcomes in patients with rheumatoid arthritis and psoriasis.

Significance to patient care

Dr. Maradit Kremers' research into the determinants of clinical outcomes and costs in total joint replacement and other musculoskeletal procedures will help enhance delivery of effective musculoskeletal care and improve outcomes for these patients.

Clinical Studies

See my clinical studies


See my publications


Administrative Appointment

  1. Associate Consultant II-Research, Division of Epidemiology, Department of Health Sciences Research
  2. Associate Consultant II-Research, Division of Orthopedic Research, Department of Orthopedic Surgery

Academic Rank

  1. Associate Professor of Epidemiology


  1. MSc - Epidemiology London School of Hygiene and Tropical Medicine
  2. Diploma Health Economics Research Unit, Aberdeen University
  3. MD Istanbul Faculty of Medicine, University of Istanbul

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