Jacksonville, Florida


Kumbhari.Vivek@mayo.edu Clinical Profile


As a physician-scientist at Mayo Clinic, Vivek Kumbhari, M.B.Ch.B., Ph.D., is an internationally recognized researcher in advanced endoscopy and endoscopic innovations with a highly cited body of published research.

Dr. Kumbhari's scientific research focus is on eliciting the underlying mechanisms of metabolic change observed after bariatric surgery and methods of liver-directed gene delivery. His clinical research focuses on novel endoscopic techniques to treat patients with obesity and complications after bariatric surgery. He has been the principal investigator on multiple active and completed research grants.

Focus areas

  • Studying retrograde organ-directed gene delivery using hydrodynamic injection
  • Evaluating the influence of the gastric mucosa on appetite, glucose and lipid homeostasis, and body weight
  • Utilizing human enteroids as a model to personalize therapy for patients with obesity and related metabolic diseases
  • Investigating endoluminal innovations to treat obesity and associated comorbidities
  • Exploring endoluminal innovations to treat complications of surgery

Significance to patient care

Translating what has been learned from research into clinically relevant therapies is a passion of Dr. Kumbhari and his team. Using preclinical models, Dr. Kumbhari explores novel approaches to fill unmet needs for patients with obesity, as well as those with single-gene disorders of the liver, pancreas and kidney.


Primary Appointment

  1. Senior Associate Consultant, Division of Gastroenterology & Hepatology, Department of Internal Medicine

Administrative Appointment

  1. Chair, Division of Gastroenterology & Hepatology, Department of Internal Medicine

Academic Rank

  1. Professor of Medicine


  1. PhD University of Sydney
  2. Fellowship - Advanced Endoscopy The Johns Hopkins University
  3. Fellowship - Gastroenterology and Interventional Endoscopy Bankstown-Lidcombe Hospital
  4. Fellowship - Gastroenterology St. George Hospital
  5. Residency - Internal Medicine Westmead Hospital
  6. Internship - Internal Medicine Liverpool Hospital
  7. MB ChB University of Otago

Clinical Studies

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