Rochester, Minnesota




Jean-Pierre A. Kocher, Ph.D., conducts research focused on developing novel analytical methods to fully leverage the data produced by high-throughput sequencing platforms and other omics technologies, with the goal of improving the diagnosis and treatment of complex diseases. Dr. Kocher's research is highly translational. Several of the developed methods are being converted into clinical applications used by Mayo Clinic's clinical laboratories to develop and implement new genomics-based clinical tests. These applications are also used by clinical teams supporting the activities of Mayo Clinic's Individualized Medicine Clinic to diagnose patients with rare, undiagnosed diseases and provide individualized drug treatments to patients with advanced cancer.

Focus areas

  • Development of the infrastructure to manage genomics data
  • Preprocessing of genomics data with an emphasis on the development of highly accurate, optimized and automated workflows
  • Interpretation of genomics variants with methods to annotate variants with curated knowledge extracted from literature and other internal or public data sources
  • Interpretation of genomics variants with methods to integrate multiple genomics data types in order to identify and prioritize variants driving the progression of diseases
  • Prioritization of drug treatment based on the genomic landscape of a tumor

Significance to patient care

Dr. Kocher's research contributes to making individualized medicine a reality. Bioinformatics is a cornerstone of individualized medicine and is key to the conversion of raw genomics data into actionable information used by clinicians to more precisely treat patients. Dr. Kocher's program contributes to advancing individualized patient care in multiple clinical areas, including oncology, cardiovascular, neurodegenerative and rare, undiagnosed diseases.

Professional highlights

  • Associate chair, Department of Biomedical Informatics, Arizona State University, 2014-present
  • Vice chair, Department of Health Sciences Research, Mayo Clinic, Arizona, 2014-present
  • Director, Bioinformatics Program, Mayo Clinic, 2012-present
  • Chair, Division of Biomedical Statistics and Informatics, Mayo Clinic, 2008-present


See my publications


Primary Appointment

  1. Consultant, Division of Biomedical Statistics and Informatics, Department of Health Sciences Research

Administrative Appointment

  1. Chair, Biomedical Statistics & Informatics, Department of Health Sciences Research

Academic Rank

  1. Professor of Biomedical Informatics


  1. PhD - in Chemical Science Universite Libre de Bruxelles
  2. Fellow - (Biotech.) from the European Community France
  3. MS - in Informatics & Theoretical Chemistry Universite Louis Pasteur
  4. Graduate (Maitrise)in Chemistry Universite Louis Pasteur
  5. License in Chemistry Universite Louis Pasteur
  6. DEUG in Biology Universite Louis Pasteur

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