Rochester, Minnesota




Wenqian Hu, Ph.D., studies molecular mechanisms of post-transcriptional regulations of gene expression in mammalian cell differentiation and responses to environmental stimuli. In particular, Dr. Hu focuses on functional and mechanistic characterization of RNA-binding proteins and noncoding RNAs in hematopoiesis and innate immune responses.

Focus areas

  • Erythropoiesis. Dr. Hu is investigating how several erythroid-specific RNA-binding proteins and long noncoding RNAs control the production of red blood cells.
  • Innate immune responses. Dr. Hu is working to decipher the post-transcriptional regulatory networks in macrophage-mediated inflammatory responses.

Significance to patient care

Dr. Hu's work focuses on fundamental molecular mechanisms underlying regulation of gene expression. Since dysregulation of gene expression is the cause of a wide variety of pathological conditions (cancer and neurodegenerative disorders, for example), the results from these basic mechanistic studies are essential for developing novel therapeutic approaches to many diseases.

Professional highlights

  • Recipient, Pathway to Independence Award (K99/R00), National Institutes of Health, 2013-2018
  • Merck Fellow, Life Science Research Foundation, 2011-2013
  • Outstanding mentoring in undergraduate research, Department of Biology, Massachusetts Institute of Technology, 2012
  • Recipient, Doctoral Excellence Award in Biochemistry, Case Western Reserve University School of Medicine, 2011
  • Predoctoral fellowship, American Heart Association, 2007-2009


Administrative Appointment

  1. Senior Associate Consultant II-Research, Department of Biochemistry and Molecular Biology
  2. Senior Associate Consultant II-Research, Department of Immunology

Academic Rank

  1. Associate Professor of Biochemistry and Molecular Biology


  1. Post-doctoral Fellowship Whitehead Institute for Biomedical Research
  2. PhD - Biochemistry and Molecular Biology Center for RNA Molecular Biology & Department of Biochemistry Case Western Reserve University, School of Medicine
  3. BS - Biological Science College of Life Science, Wuhan University

Clinical Studies

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