Clifton R. Haider, Ph.D., studies the methods by which health care researchers design and field autonomous, noninvasive physiologic monitors to extract predictive biomarkers in human performance, sleep disorders, cardiovascular and neurodegenerative disease, as well as cardiovascular collapse in trauma and surgery.
Today there exist countless unmet pediatric and adult clinical needs for which physiological monitoring is a necessity. However, medical device development is time-consuming — requiring iterative design through clinical trials and device and sensor modification. In order to accelerate device development, Dr. Haider has established a mathematical, algorithmic, software and laboratory discovery platform for novel physiologic sensing.
The discovery platform incorporates statistical modeling, design and demonstration of physiologic sensor limits to ensure that the first medical device prototype captures the pathophysiology of interest. The numerical design phase is immediately followed by integration of the new sensor into a scalable Mayo Clinic-developed miniature physiologic monitor that permits on-body validation.
- Accelerated medical device design
- Noninvasive, autonomous physiologic monitoring
- Quantitative, predictive physiologic biomarkers
- Real-time predictive algorithms
- Remote pediatric monitoring
Significance to patient care
Dr. Haider's intent is that through his physiologic monitoring discovery platform and algorithmic identification of novel biomarkers, he will be able to predict which patients are responding to treatment and why nonresponding patients need more-advanced care.
- Office of Naval Research Young Investigator Program, 2014-present