Location

Jacksonville, Florida

Contact

fernandez-bussy.sebastian@mayo.edu Clinical Profile

SUMMARY

Sebastian Fernandez-Bussy, M.D., is an interventional pulmonologist whose international training demonstrates his deep commitment to innovation, global collaboration and mentorship. As the James C. and Sarah K. Kennedy Dean of Research at Mayo Clinic in Florida, Dr. Fernandez-Bussy provides strategic and operational leadership for research at Mayo's Florida campus. His broad expertise in multiple disciplines informs transformative research and helps drive the development of innovative, patient-centered solutions for serious and complex diseases.

Dr. Fernandez-Bussy's clinical research advances minimally invasive pulmonary procedures. His research focuses on translating emerging technologies in bronchoscopy — including ablation and pulsed-electrical field — into improved patient care. This translational foundation supports ongoing and future studies exploring artificial intelligence (AI)-driven, noninvasive diagnostic tools including vocal biomarker analysis. By combining advanced bronchoscopic diagnostics with low-risk screening approaches, he aims to expand the diagnostic tools and enable earlier, accessible detection of lung disease.

Focus areas

  • AI-driven biomarkers.
  • Chronic obstructive pulmonary disease (COPD).
  • Central airway disorders.
  • Device innovation.
  • Endomicroscopy.
  • Lung cancer.
  • Minimally invasive ablation therapy for thoracic cancers.
  • Molecular integration.
  • Robot-assisted bronchoscopy.
  • Translational bronchoscopy.

Significance to patient care

Dr. Fernandez-Bussy's research and research leadership advance discovery and improve patient outcomes through collaboration, creativity and excellence. Learn more about how his work reduces the need for transplants in patients with advanced lung disease on Mayo Clinic's medical innovations website.

Professional highlights

  • Mayo Clinic:
    • James C. and Sarah K. Kennedy Dean of Research, Mayo Clinic in Florida, 2026-present.
    • Florida faculty representative, International Clinical Practice Committee, Mayo Clinic, 2021-present.
    • Associate chair, Faculty Development and Academic Affairs, Mayo Clinic in Florida, 2020-present.
    • Director, Procedure Innovation Team, Mayo Clinic in Florida, 2020-present.
    • Director, Section of Interventional Pulmonology, Division of Pulmonary Medicine, Mayo Clinic in Florida, 2018-present.
    • Top Performing Provider Patient Experience Award, Mayo Clinic in Florida, 2022.
  • Visiting professor, Heidelberg University, Germany, 2018-present.
  • Director, Endoscopy Department, Latin American Thoracic Society, Uruguay, 2018-present.

PROFESSIONAL DETAILS

Primary Appointment

  1. Consultant, Division of Pulmonary, Allergy and Sleep Medicine, Department of Internal Medicine
  2. Division Chair, Division of Pulmonary, Allergy and Sleep Medicine, Department of Internal Medicine
  3. Dean, Department of Research

Academic Rank

  1. Professor of Medicine

EDUCATION

  1. Certificate - Program Clinical Effectiveness Harvard School of Public Health
  2. Trainee - Interventional Pulmonology University of Heidelberg
  3. Fellowship - Division of Pulmonary, Critical Care, and Sleep Medicine University of Florida College of Medicine
  4. Fellowship - HIV/AIDS Medicine, Division of Infectious Diseases University of Texas - Houston
  5. Fellowship - Critical Care Medicine Universidad del Salvador
  6. Residency Internal Medicine Society of Buenos Aires
  7. MD Salvador University School of Medicine

Clinical Studies

Learn about clinical trials that address specific scientific questions about human health and disease.

See my studies.

Explore all research studies at Mayo Clinic.

Publications

See the peer-reviewed findings I have published as a result of my research.

Review publications.
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BIO-20602802

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