Brain tumor, breast cancer, colon cancer, congenital heart disease, heart arrhythmia. See more conditions.
As a statistical geneticist, Brandon J. Coombes, Ph.D., focuses his studies on polygenic risk scores, gene-environment interactions and electronic health record (EHR) research. Dr. Coombes is a collaborative scientist studying the genetics of complex diseases, particularly in psychiatric disorders such as bipolar disorder, opioid use disorder, alcohol use disorder, depression and anxiety.
Bipolar disorder. Dr. Coombes provides statistical genetics and biostatistics support for Mayo Clinic's Bipolar Disorder Biobank led by Joanna M. Biernacka, Ph.D., and Mark A. Frye, M.D.
This research contributes to analyses in the largest genetic study of bipolar disorder conducted by the Psychiatric Genomics Consortium as well as the largest pharmacogenomic study of bipolar disorder conducted by the Consortium on Lithium Genetics and the Mood-Stabilizer Genomics Consortium.
By furthering understanding of the biological etiology of psychiatric illness, Dr. Coombes improves the diagnosis, prevention and development of novel therapies for psychiatric problems. Testing for genetic risk of traits is now offered directly to consumers. It is critical to consider how to best bring these risk estimates into the clinic. This allows personalized medicine and precision psychiatry and ensures they are applied equitably.
Learn about clinical trials that address specific scientific questions about human health and disease.
Explore all research studies at Mayo Clinic.
See the peer-reviewed findings I have published as a result of my research.
Review my research fingerprint, network, grants, projects, publications, Scopus profile, and Altmetrics scores and badges.
Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. Mayo Clinic does not endorse any of the third party products and services advertised.
A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.