Rochester, Minnesota


Clarke.Michelle@mayo.edu Clinical Profile


Dr. Clarke studies spinal column and spinal cord tumors from a clinical and translational research perspective, focusing on novel surgical techniques and optimizing patient outcomes. This includes multicenter and multidisciplinary prospective and collaborative projects on rare primary tumors of the spine.

Focus areas

  • Primary spinal column tumors. Dr. Clarke contributes to a multi-institutional study of rare primary spinal column tumors, their treatment, outcome and effect on patient quality of life. Specifically, this work focuses on optimizing multimodality treatment delivered in a collaborative environment.
  • Degenerative spine disease. An additional area of focus is the delivery of high-quality, timely and cost-effective care for degenerative spine disease through the use of quality-of-life metrics.
  • Tumor treatment. Dr. Clarke also studies intradural and spinal cord tumor treatment, with multi-institutional collaboration.

Significance to patient care

Dr. Clarke's hope is that through her research, better tools will be developed to counsel and treat patients suffering from spinal cord or spinal column tumors. She aims to understand the causes, study improvements to treatment, and determine the best method of treatment delivery for these rare and unusual tumors.

Clinical Studies

See my clinical studies


See my publications


Primary Appointment

  1. Consultant, Department of Neurologic Surgery

Academic Rank

  1. Professor of Neurosurgery
  2. Professor of Orthopedics


  1. Masters - Bioethics Loyola University Chicago
  2. Certificate - Education Science Career Development Award (ESCDA) and Endowment for Education Research Award (EERA) for Mayo faculty who wish to pursue education research as a significant component of their careers. Participants gain skills in education research and have the opportunity to create high-quality research protocols to study an education research question of their choice. Mayo Clinic, The Office of Applied Scholarship and Education Science (OASES)
  3. Fellow - Spine The Johns Hopkins University School of Medicine
  4. Chief Resident Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  5. Resident - Department of Neurologic Surgery Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  6. Research Fellowship - Pursue translational research in the field of neuro-oncology Clinician-Investigator Training Program, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  7. Research Fellowship - NIH Training Grant NS07494-0 Mayo Clinic Department of Neurology (Neurooncolgy)
  8. MD Georgetown University School of Medicine
  9. BSE - Aerospace Engineering Minor Biology/Neuroscience Princeton University
  10. Research Fellowship - Biomedical Engineering Institute of Medical Science, University of Toronto
  11. M.Ed. - Medical and Adult Education University of Cincinnati

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