Rochester, Minnesota


Chiang.Chia-Chun@mayo.edu Clinical Profile


The research of Chia-Chun Chiang, M.D., pertains to all facets of the association between migraine and stroke. Dr. Chiang focuses on the management of headache in people with vascular disorders. She uses novel artificial intelligence (AI) and learning techniques to improve outcomes in patients with headache or cerebrovascular disorders.

Focus areas

  • Studies have shown that there is an increased risk of stroke in patients with migraine and especially those who have migraine with aura. Dr. Chiang's research focuses on studying the mechanisms behind such association. She has collaborated with Mayo Clinic Department of Cardiology and identified an association between migraine aura and atrial fibrillation using a novel AI-ECG algorithm.
  • Dr. Chiang has published extensively on the management of headache in patients with various cerebrovascular disorders. This includes moyamoya disease, cavernous malformation and cerebral venous sinus thrombosis.
  • Dr. Chiang has conducted extensive data research on determining headache phenotype subgroups based on an established headache database at Mayo Clinic's campus in Rochester, Minnesota. Additionally, Dr. Chiang's team and collaborators have developed a natural language processing model to identify migraine reported on social media.

Significance to patient care

Both migraine and stroke are leading causes of disability throughout the world. Identifying the association between migraine and stroke can help reduce the chances of developing adverse cerebrovascular and cardiovascular events in people with migraine. Currently, there are no accurate ways to predict treatment outcomes in patients with migraine. Sometimes it can take months or years before treatments are effective. Improving treatment outcomes can reduce the time and pain for many people.

Professional highlights

  • Visiting scholar, Stanford University, 2023-present.
  • Faculty member, Resident Education for Assessment and Care for Headache Program, American Headache Society, 2022-present.
  • Faculty member, Scientific Program Committee and Electronic Media Committee, American Headache Society, 2022-present.
  • Representative of the Headache and Stroke Division, Neurology Artificial Intelligence Program, Mayo Clinic, 2021-present.
  • Editorial board member, American Migraine Foundation, 2020-present.
  • Early Career Award, American Headache Society, 2022.
  • International Headache Academy Program Nominated Scholarship Award, American Headache Society, 2017, 2018, 2020, 2021, 2022.
  • Emerging Leaders Program Scholarship Award, American Headache Society, 2021.
  • Assistant editor, Headache: The Journal of Head and Face Pain, 2019-2021.
  • Frontiers in Headache Research Scholarship Award, American Headache Society, 2017, 2020.
  • Manfred D. Muenter Award, Neurology Residency, Mayo Clinic, 2018.


Primary Appointment

  1. Consultant, Department of Neurology

Academic Rank

  1. Assistant Professor of Neurology


  1. Fellow - Headache Medicine Mayo School of Graduate Medical Education
  2. Fellow - Vascular Neurology University of California, San Diego
  3. Chief Resident - Neurology Mayo School of Graduate Medical Education
  4. Resident - Neurology Mayo School of Graduate Medical Education
  5. Prelim Resident Transitional Year Residency, Transitional Year, Programs in Arizona, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  6. Resident - Transitional Year/Internship Mayo School of Graduate Medical Education
  7. Postdoctoral Research Fellowship - Neuroscience University of California, San Diego
  8. Internship Taipei Veterans General Hospital
  9. MD National Yang-Ming University
  10. Visiting Scholar - Artificial Intelligence/Machine Learning in Healthcare (Stanford University Human Artificial Intelligence Institute) Stanford University

Clinical Studies

Learn about clinical trials that address specific scientific questions about human health and disease.

Explore all research studies at Mayo Clinic.


See the peer-reviewed findings I have published as a result of my research.

Review publications.

Mayo Clinic Footer