Rochester, Minnesota


Caples.Sean@mayo.edu Clinical Profile


The research activities of Sean M. Caples, D.O., focus on sleep-disordered breathing, particularly cardiovascular manifestations of the sleep apnea syndromes and clinical trials to measure the effects of various treatment modalities.

Focus areas

  • Atrial fibrillation and sleep apnea. Dr. Caples is studying the link between atrial fibrillation and sleep apnea and exploring whether treatment of sleep apnea affects the natural history of this common heart rhythm problem.
  • Non-CPAP treatments of sleep apnea. Dr. Caples has studied the effects of non-CPAP treatments on outcomes in patients with sleep apnea.

Significance to patient care

Dr. Caples is interested in better understanding the relationship between sleep apnea syndromes and cardiovascular disease in order to advance treatment of both conditions.

Professional highlights

  • Member, Positive Airway Pressure Guideline Task Force, American Academy of Sleep Medicine (AASM), 2013-present
  • Chair, Task Force on Surgical Modifications of the Upper Airway for the Treatment of Obstructive Sleep Apnea, AASM, 2010
  • Co-chair, Revised Sleep Scoring Manual Cardiac Task Force, AASM, 2007


Primary Appointment

  1. Consultant, Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine
  2. Section Head, Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine

Academic Rank

  1. Professor of Medicine


  1. MSc - Clinical Research Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic College of Medicine and Science
  2. BASIC SCIENCE MASTERS Clinical and Translational Science, Programs, Mayo Graduate School, Mayo Clinic College of Medicine
  3. Pulmonary and Critical Care Mayo Clinic in Rochester
  4. Fellow - Sleep Medicine Mayo Clinic in Rochester
  5. Fellow - Pulmonary and Critical Care Mayo Clinic in Rochester
  6. Resident - Internal Medicine Bassett Healthcare, College of Physicians and Surgeons, Columbia University, New York, NY
  7. Doctor of Osteopathic Medicine New York Institute of Technology
  8. BS - Pharmacy State University of New York at Buffalo

Clinical Studies

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