Jacksonville, Florida Clinical Profile


Thomas G. Brott, M.D., is professor of neurology and director for research at the Mayo Clinic in Jacksonville, Fla., where he is also the Eugene and Marcia Applebaum Professor of Neurosciences, as well as the James C. and Sarah K. Kennedy Dean for Research. In addition, he is adjunct professor in the Department of Surgery at the University of Medicine and Dentistry of New Jersey in Newark, N.J. A pioneer in the field of stroke and cerebrovascular disease research, Dr. Brott was a leading investigator in the studies that identified tissue plasminogen activator (t-PA) as an effective acute treatment for ischemic stroke. He also played a key role in designing the National Institutes of Health Stroke Scale (NIHSS). Currently, Dr. Brott is principal investigator for the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST) and national co-principal investigator of the Siblings with Ischemic Stroke Study (SWISS), both funded by NINDS. Dr. Brott received his M.D. from the University of Chicago and completed his residency at the Harvard Longwood Neurology Program. He has received many awards and honors and has held several national leadership positions, including chair of the Advisory Committee to the Neurological Devices Panel of the Food and Drug Administration and chair of the Stroke Council of the American Heart Association. He is a member of numerous professional societies and is widely published in the field.


Primary Appointment

  1. Consultant, Department of Neurology

Academic Rank

  1. Professor of Neurology


  1. Fellow - Clinical Fellow in Neurology Harvard University
  2. Resident - Neurology Harvard Longwood Neurology Program, Beth Israel Hospital/Children's Hospital/Brigham and Women's Hospital
  3. Internship - Medicine Beth Israel Hospital, Harvard Medical School
  4. MD University of Chicago
  5. Urban Studies Fellowship University Of Chicago Pritzker School Of Medicine
  6. Special Student Graduate School of Arts and Sciences, Harvard University
  7. AB Harvard College

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