Rochester, Minnesota


Daniel J. Berry, M.D., is an orthopedic surgeon with a lifelong commitment to research that improves the outcomes, quality, reliability and durability of hip and knee replacements.

Dr. Berry's research uses data from numerous sources, including electronic health records, disease-specific registries and national data repositories.

Dr. Berry has published more than 300 peer-reviewed articles on a broad spectrum of topics in hip and knee replacement, including long-term outcomes and incidence and management of common complications — such as infection, joint instability and fractures around joint replacements. Additional published research addresses surgical techniques to manage complex hip and knee replacements and revision hip and knee replacement problems. He is also the editor of eight textbooks on hip and knee replacement.

Dr. Berry has been involved in numerous national health policy initiatives, including helping to found and develop the American Joint Replacement Registry.

Dr. Berry is the director of the Core Center for Clinical Research in Total Joint Arthroplasty (CORE-TJA) at Mayo Clinic, which is funded by a National Institute of Arthritis and Musculoskeletal and Skin Diseases P30 grant. The center provides access to state-of-the-art methodological expertise, education and big data resources to accelerate methodologically rigorous clinical research that will directly improve the care and outcomes of patients receiving hip and knee replacements.

Focus areas

  • Surgical techniques and implants in joint replacement. Surgical techniques and implants in total hip and knee replacement are constantly evolving as a result of emerging technologies. Dr. Berry's research focuses on evaluating the results of primary and revision joint replacement in a wide variety of common and less common diagnoses and clinical settings.

    His research provides information on risk predictors for complications such as infection, implant loosening and joint instability and on developing and delineating the most successful management strategies for these complications. Dr. Berry also studies and has been involved in developing and refining the field of revision hip and knee replacement.

  • Orthopedics policy and quality research. Dr. Berry conducts policy-relevant research in orthopedics through collaborative and single-institution studies. These studies include surgeon workforce, risk-standardized outcome measures and risk scores in total joint replacement. His work has implications not only for research but also for decision-making by patients, orthopedic surgeons and surgical staff, and insurers.
  • Orthopedics epidemiologic and outcomes research. Using various data sources, Dr. Berry studies epidemiologic trends in total hip and knee replacement in the United States. His research covers clinical and device outcomes, including long-term outcomes according to implant types and patient characteristics such as body mass index.

Significance to patient care

Dr. Berry's work has the potential to significantly impact treatment of patients with hip and knee disorders. His work on risk assessment, risk mitigation, and understanding and optimizing the results of specific surgical techniques helps to improve orthopedic care and outcomes for joint replacement patients.

Additionally, Dr. Berry's epidemiologic studies provide information on the public health impact of total joint replacement and guide clinical practice, research and policy in orthopedics.

Professional highlights

  • Member, Board of trustees, Orthopaedic Research and Education Foundation, 2019-present
  • Senior director, Current Concepts in Joint Replacement, 2019-present
  • Member, Steering committee, AO Recon, 2017-present
  • President-elect, International Hip Society, 2017-present
  • Member, Board of trustees, Journal of Bone and Joint Surgery, 2013-2020
  • John Charnley Award, for the paper "Increased PJI Risk Following Primary TKA and THA With Alternatives to Cefazolin: The Value of Allergy Testing for Antibiotic Prophylaxis," The Hip Society, 2019
  • Lawrence D. Dorr Surgical Techniques & Technologies Award, for the paper "Why Are Contemporary Revision Total Hip Arthroplasties Failing? An Analysis of 2500 Cases," American Association of Hip and Knee Surgeons annual meeting, Dallas, 2018
  • Best Poster Award in Primary Total Hip Arthroplasty, for the paper "Does Timing of Primary Total Hip Arthroplasty Prior to or After Lumbar Spine Fusion Have an Effect on Dislocation and Revision Rates?" American Association of Hip and Knee Surgeons, 2017
  • Orthopaedic Research and Education Foundation Clinical Research Award, for the paper "Arthroplasty Implant Registries Over the Past Five Decades: Development, Current and Future Impact" American Academy of Orthopaedic Surgeons annual meeting, San Diego, 2017
  • Past president, Hip Society, 2015-2016
  • Edmond A. and Marion F. Guggenheim Professor, 2015
  • Chairman emeritus, Mayo Clinic Department of Orthopedic Surgery, 2005-2014
  • John Charnley Award, for the paper "Clinical Multi-Centric Studies of the Wear Performance of Highly Cross-Linked Re-Melted Polyethylene in THR," Hip Society, 2012
  • Past president, American Academy of Orthopaedic Surgeons, 2011-2012
  • L. Z. Gund Professorship in Orthopedics, 2008


Primary Appointment

  1. Consultant, Department of Orthopedic Surgery

Academic Rank

  1. Professor of Orthopedics


  1. Fellow - Adult Reconstructive Surgery Mayo Clinic in Rochester
  2. Chief Resident - Orthopaedic Surgery Brigham and Women's Hospital
  3. Resident - Orthopaedic Surgery Harvard Combined Orthopaedic Residency Program, Brigham and Women's Hospital
  4. Resident - Orthopaedic Surgery Harvard Combined Orthopaedic Residency Program, Children's Hospital
  5. Resident - Orthopaedic Surgery Harvard Combined Orthopaedic Residency Program, Massachusetts General Hospital
  6. Internship - General Surgery Harvard Fifth Surgical Service, New England Deaconess Hospital
  7. Junior Resident - General Surgery Harvard Fifth Surgical Service, New England Deaconess Hospital
  8. MD Harvard Medical School
  9. BA Dartmouth College

Clinical Studies

Learn about clinical trials that address specific scientific questions about human health and disease.

Explore all research studies at Mayo Clinic.


See the peer-reviewed findings I have published as a result of my research.

Review publications.

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