Brain tumor, breast cancer, colon cancer, congenital heart disease, heart arrhythmia. See more conditions.
The research interests of Adebowale (Wale) O. Bamidele, Ph.D., center on better understanding the role of CD4 T lymphocytes in the initiation and progression of inflammatory bowel disease (IBD). How nutrient metabolism governs the function of CD4 T lymphocytes to drive disease, mainly Crohn's disease and ulcerative colitis, is of interest given its therapeutic significance to disease treatment.
Dr. Bamidele also investigates the mechanisms of resistance to biologics, considering that the refractory nature of this disease is a major clinical concern. Mechanisms being currently investigated include metabolic cues and cell-to-cell interactions that redundantly reinvigorate pathogenic CD4 T lymphocyte expansion and function.
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