Location

Rochester, Minnesota

Contact

bakri.sophie@mayo.edu Clinical Profile

SUMMARY

Sophie J. Bakri, M.D., is a vitreoretinal specialist with expertise in diseases and surgery of the retina and vitreous. Dr. Bakri's research focuses on age-related macular degeneration, diabetic retinopathy, retinal vascular occlusive diseases, and the management of complex retinal detachments, including proliferative vitreoretinopathy. She leads both clinical and translational research to advance the understanding of the pathogenesis and treatment of retinal diseases.

Focus areas

  • Clinical trials in retinal diseases.
  • Therapeutic approaches for retinal diseases, including:
    • Pharmacologic therapies for age-related macular degeneration.
    • Diabetic retinopathy.
    • Retinal vascular occlusive disease.
    • Macular telangiectasia.
    • Gene and cell-based therapies.
  • Pharmacokinetics and tissue distribution of intravitreal therapeutics.
  • Clinical outcomes of pharmacologic treatments for retinal disease.
  • Clinical and translational research in proliferative vitreoretinopathy and retinal fibrosis.

Significance to patient care

Dr. Bakri studies why patients respond differently to treatments for retinal diseases. She studies how medicines move through the eye and affect eye tissue. She also studies scarring in the retina and proliferative vitreoretinopathy. Dr. Bakri's research helps care teams develop more precise treatments, improve patient outcomes, lower side effects and provide more personalized care.

Professional highlights

  • Medical Director, Center for Digital Health, Mayo Clinic, 2026-present.
  • Top Doctor, Minnesota Monthly Top Doctors, 2020-present.
  • Whitney and Betty MacMillan Professor of Ophthalmology in Honor of Robert R. Waller, M.D., Mayo Clinic, 2020-present.
  • Inductee, Retina Hall of Fame, 2019.
  • Senior Achievement Award, American Academy of Ophthalmology, 2018.
  • Senior Honor Award, American Society of Retina Specialists, 2018.
  • Castle Connolly Top Doctor, 2011, 2015, 2016, 2017.

PROFESSIONAL DETAILS

Primary Appointment

  1. Consultant, Department of Ophthalmology
  2. Medical Director, Center for Digital Health

Administrative Appointment

  1. Chair, Department of Ophthalmology

Academic Rank

  1. Professor of Ophthalmology

EDUCATION

  1. MBA The Wharton School, University of Pennsylvania
  2. Fellow - Vitreoretinal Diseases and Surgery Cole Eye Institute, Cleveland Clinic Foundation
  3. Chief Resident - Ophthalmology Lions Eye Institute, Albany Medical College
  4. Resident - Ophthalmology Lions Eye Institute, Albany Medical College
  5. Internship - Internal Medicine Albany Medical College
  6. House Officer - Surgery, Medicine University of Nottingham Hospitals
  7. BMBS - Bachelor of Medicine, Bachelor of Surgery University of Nottingham Medical School
  8. Advanced Levels Uppingham School
  9. General Certificate of Secondary Education Penrhos College

Clinical Studies

Learn about clinical trials that address specific scientific questions about human health and disease.

See my studies.

Explore all research studies at Mayo Clinic.

Publications

See the peer-reviewed findings I have published as a result of my research.

Review publications.
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BIO-00027319

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