Location

Rochester, Minnesota

Contact

Adams.Christopher2@mayo.edu

SUMMARY

The research interests of Christopher M. Adams, M.D., Ph.D., focus on molecular mechanisms of skeletal muscle atrophy, diabetes and obesity.

Focus areas

  • Identification and characterization of novel molecular mechanisms of skeletal muscle atrophy and weakness. Dr. Adams' mechanistic studies combine unbiased, discovery-oriented molecular and biochemical approaches in human and mouse skeletal muscle with targeted molecular genetic interventions in mouse skeletal muscle. This work is elucidating essential components of a previously unrecognized and evolutionarily conserved molecular pathway that promotes skeletal muscle atrophy and weakness during starvation, muscle disuse, and aging.
  • Discovery and development of novel approaches for the maintenance of skeletal muscle health and the treatment of skeletal muscle atrophy, diabetes, and obesity. Dr. Adams is the lead inventor on over 30 patents concerning small molecules that help maintain the structure and function of skeletal muscle. He leads a biotechnology company that is translating this research in collaboration with global companies and his laboratory at Mayo Clinic.

Significance to patient care

The overall goal of this research is to help generate new medicines, nutritional approaches and diagnostic tools for skeletal muscle atrophy, diabetes, and obesity.

Professional highlights

  • Research chair, Division of Endocrinology, Diabetes, Metabolism, Nutrition, Mayo Clinic, Rochester, Minnesota, 2021-present
  • Elected member, American Society for Clinical Investigation, 2013-present
  • Founder, president and CEO, Emmyon, Inc., 2012-present
  • Research chair, Fraternal Order of Eagles Diabetes Research Center, University of Iowa, 2017-2021
  • Professor of Medicine with tenure, University of Iowa, 2015-2021
  • Senior Clinical Scientist Award, U.S. Department of Veterans Affairs, 2019
  • Chair, Skeletal Muscle Biology and Exercise Physiology Study Section, National Institutes of Health, 2018-2019
  • Standing member, Skeletal Muscle Biology and Exercise Physiology Study Section, National Institutes of Health, 2014-2018
  • Inaugural Faculty Scholar, Fraternal Order of Eagles Diabetes Research Center, University of Iowa, 2011-2016
  • Associate Professor of Medicine with tenure, University of Iowa, 2011-2015
  • Assistant Professor of Medicine, University of Iowa, 2006-2011
  • Clinical Scientist Development Award, Doris Duke Charitable Foundation, 2009
  • Assistant Professor of Medicine, University of Texas Southwestern Medical Center, 2005-2006

PUBLICATIONS

See my publications

PROFESSIONAL DETAILS

Primary Appointment

  1. Senior Associate Consultant, Division of Endocrinology, Diabetes, Metabolism, Nutrition, Department of Internal Medicine
  2. Research Chair, Division of Endocrinology, Diabetes, Metabolism, Nutrition, Department of Internal Medicine

Joint Appointment

  1. Senior Associate Consultant, Department of Biochemistry and Molecular Biology

Academic Rank

  1. Professor of Medicine

EDUCATION

  1. Fellowship - Physician Scientist Training Program (PSTP). Clinical fellowship in Endocrinology, Diabetes and Metabolism. Postdoctoral research on molecular regulation of cholesterol metabolism. Mentored by Drs. Michael S. Brown, M.D. and Joseph L. Goldstein, M.D. University of Texas Southwestern Medical Center
  2. Internship/Residency - Internal Medicine. University of Texas Southwestern Medical Center
  3. MD / PhD - Physiology and Biophysics. Medical Scientist Training Program (MSTP). Graduate school research to discover and characterize non-voltage-gated sodium channels in humans and Drosophila. Mentored by Dr. Michael J. Welsh, M.D. University of Iowa
  4. BS - Cellular Biology. Undergraduate research on microtubule dynamics in Chlamydomonas. Mentored by Dr. William Dentler, Ph.D. University of Kansas
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BIO-20526049

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