SUMMARY
Jad P. AbiMansour, M.D., is a gastroenterologist and advanced endoscopist who studies the use of complex endoscopic procedures to diagnose, manage and treat diseases of the pancreas and bile duct. He has a passion for developing novel endoscopic devices and translating technological advancement from research to patient care.
Dr. AbiMansour's work on pancreatic neuroendocrine tumors addresses a rare but increasingly prevalent type of cancer. These lesions are commonly found incidentally and can have a relatively benign course. But they also can result in significant stressors and anxiety for patients because little is known about how to optimally monitor or treat the condition.
There are increasing options for minimally invasive endoscopic treatment of pancreatic neuroendocrine tumors. Dr. AbiMansour's research seeks to stratify the risk posed by these lesions, to ultimately allow delivery of the right treatment to the right patient at the right time.
Overall, the field of gastrointestinal endoscopy is advancing at a rapid pace, and gastroenterologists are now able to treat many conditions that previously required surgery. Dr. AbiMansour hopes to help advance rigorous preclinical and clinical research required to drive technological advancement, validate efficacy and translate innovation to patient care.
Dr. AbiMansour also is a principal investigator of the Developmental Endoscopy Laboratory, which develops new devices and technology, designs and conducts clinical studies, and offers education and training in advanced endoscopic procedures.
Focus areas
- Pancreatic neuroendocrine tumors. Dr. AbiMansour studies how to optimize diagnostic, surveillance and treatment pathways for tumors localized to the pancreas.
- Endoscopic ultrasound (EUS)-guided ablation. Dr. AbiMansour is developing tools and techniques to provide safe, minimally invasive, organ-sparing treatment of lesions with EUS.
- Novel endoscopic devices. Preclinical development and validation of novel endoscopic devices may enable endoscopic treatment of diseases that previously could only be treated with surgery.
- Pancreatitis. Dr. AbiMansour is studying endoscopic management of pancreatitis and its complications, such as necrotizing pancreatitis. He's also working to define the microbial makeup of peripancreatic fluid collections undergoing EUS-guided drainage.
Significance to patient care
Pancreatic neuroendocrine tumors are a rare type of cancer that starts as a growth of cells in the pancreas. Dr. AbiMansour's research helps with better understanding of these tumors. His goal is to make sure people with this condition get the monitoring or treatment plans that are right for them. Finding less invasive treatment options helps patients heal faster and avoid surgery when possible.
Professional highlights
- Member, editorial board, iGIE, 2025-present.
- Shirley Fiterman Award, Excellence in Teaching and Professionalism, Division of Gastroenterology and Hepatology, Mayo Clinic, 2023.
- Richard W. Reilly Award for Outstanding Aptitude in Gastroenterology, University of Chicago Pritzker School of Medicine, 2017.