Infectious Diseases Research

Below are current clinical trials.

259 studies in Infectious Diseases Research
(all studies, either open or closed).

Filter this list of studies by location, status and more.

1. COVID-19 and Acute Renal Failure

   Jacksonville, Fla., Scottsdale/Phoenix, Ariz., Rochester, Minn.

   The primary purpose of this study is to examine 1-year survival and rate of secondary infections in COVID-19 patients with and without acute kidney injury (AKI).

    

    

    

2. Evaluation of patients perceived health and fitness prior to surgery during the COIVD 19 pandemic

   Rochester, Minn.

   The primary aim of this study is to assess colon and rectal surgery patient perceptions of physical fitness, willingness to participate in a prehabilitation program, access to cardiovascular and strength training equipment, and impact of the COVID19 pandemic on fitness and health. The secondary aim is to evaluate if patient’s perceptions of physical fitness correlate with baseline demographic and health variables and outcomes following surgery.

3. Genetic Expression in Osteolysis, Infection, Arthrofibrosis & Metal Reactions in THA & TKA: A Microarray Analysis to Characterize Individual Host Response to the Molecular Mechanisms of Loosening and Arthrofibrosis

   Rochester, Minn.

   This study is being conducted to determine gene and protein expression profiles (i.e. which genes and proteins are turned off and on) of those with a possibility of developing osteolysis, infection, arthrofibrosis or metallosis of their THA/TKA.

4. Laboratory Assay Optimization 2.0

   Rochester, Minn.

   The purpose of this study is to better understand the role of HIV and/or HCV infection and/or SARS-CoV-2 on the immune system and potential ways to eliminate the virus(es).

5. A Study to Evaluate Positive SARS-CoV-2 Antibodies in Subjects with Bipolar Disorder

   Rochester, Minn.

   The purpose of this study is to evaluate the clinical and neurocognitive correlates of COVID-19 in patients with bipolar disorder (BD). 

6. A Study To Assess The Safety, Tolerability And Effectiveness Of Monoclonal Antibodies To Treat Hospitalized Patients With COVID-19

   Rochester, Minn.

   The purpose of this study is to evaluate the effectiveness, safety, and tolerability of REGN10933+REGN10987 in hospitalized adult patients with COVID-19.

7. Negative Pressure Wound Therapy for Prevention of Poststernotomy Infection

   Rochester, Minn.

   Does a wound vac dressing prevent wound infection after heart surgery?

8. A Study Evaluating The Safety And Effectiveness Of Anti-Influenza Intravenous Hyperimmune Immunoglobulin (IVIG) For Adults Hospitalized With Influenza

   Rochester, Minn.

   Influenza (the flu) is a common illness that usually occurs in autumn and winter. The flu is usually mild, but can cause serious illness or death. The purpose of this study is to test the safety and effectiveness of an antibody against the flu (called intravenous hyperimmune immunoglobulin or IVIG) in people who are hospitalized for severe flu.

9. Detection of Infection in Arthroplasty

   Rochester, Minn.

   The purpose of this study is to determine the sensitivity, specificity, positive and negative predictive values of molecular detection of microorganisms, detection of microbial proteins and antibodies against microorganisms, and inflammatory markers (e.g., leukocyte esterase, CRP) in synovial fluid for the diagnosis of prosthetic joint infection (PJI).

10. A Study to Evaluate the Characteristics and Role of Mucosal Microbiome after Treatment of Clostridium-difficile Infection

    Rochester, Minn.

    The purpose of this study is to characterize the mucosal microbiome in patients who have recently been treated for Clostridium-difficile Infection (CDI) in comparison to that of control population to determine the effect of the mucosal associated microbiome on outcome of CDI.