A lab technologist wearing green gloves places a slide into a microscope with the microscope objectives shown in the background.

Facilities and equipment

Facilities

The Spatial Multiomics Core has about 400 square feet of laboratory space on Mayo Clinic's campus in Rochester, Minnesota.

Equipment

The Spatial Multiomics Core has several instruments supporting service workflows:

  • Bruker NanoString GeoMx Digital Spatial Profiler.
  • Vizgen Merscope.
  • 10x Genomics CytAssist for use with standard Visium and Visium HD.
  • Agilent Bioanalyzer.
  • Bio-Rad T100 Thermal Cyclers.
  • Keyence BZ-X multifunctional microscope for slide scanning and image stitching.

In addition, the Spatial Multiomics Core also has these instruments to support development activities:

  • 10x Genomics Chromium X.
  • Revvity Cellometer K2.
  • AtlasXomics docking station and Gen 3 FlowGel chip holder for Spatial ATAC-seq and CUT&Tag using deterministic barcoding in tissue-sequencing (DBiT-seq).
  • BioRad CFX Opus 96 real-time polymerase chain reaction system.