About the Core

Staff member pipetting in the Immunochemical Core laboratory at Mayo Clinic in Minnesota.

On average each year, the core supports 130 research protocols for 50 to 75 investigators.


Immunochemical Core staff members include a director, a laboratory assistant, four senior research technologists, two development technologists, a quality specialist and a laboratory manager.

Investigators using the core benefit from the extensive depth of personnel experience, as the average tenure of Immunochemical Core technologists is 23 years. All technologists undergo annual competency training and also have documented training for the specific techniques and assays they perform.

Overseeing the core is director Ravinder J. Singh, Ph.D. Dr. Singh provides expertise in the disciplines of endocrinology and chemistry and also has extensive experience with mass spectrometry techniques.

Research and development

Upon request, the Immunochemical Core can test most assays or kits available on its current platforms.

For novel assay development, the core evaluates each project on an individual basis. New development projects require a consultation meeting to discuss the project's specifics and the capabilities of the core to perform the development work. Fee details also are discussed.

For assays on sample types that the core has not validated, an initial pilot study may be needed to ensure that the specimen type is appropriate to obtain accurate results.

Contact the core for more information.


Name Code Platform
7-alph C4 ALPHC mass spectrometry
Albumin CALB cobas c 311
Brain Natriuretic Peptide (BNP) CBNP Beckman Coulter DxI
Brain Natriuretic Peptide, NT-pro (NTproBNP) NTBNP cobas e 411
Cholesterol, total CCHOL cobas c 311
Cortisol, total CCOR Beckman Coulter DxI
C-peptide, human CCPH cobas e 411
C-reactive protein CCRP cobas c 311
Estrogens, estrone (E1) and estradiol (E2) ESTMS mass spectrometry
Follicle-stimulating hormone (FSH) CFSH Beckman Coulter DxI
Glucagon 7659 RIA
Glucagon-Like Peptide 1, active CGLP1 ELISA
Glucose CGLU cobas c 311
High-density Lipoprotein (HDL) Cholesterol CHDL cobas c 311
Insulin (plasma) PINSH Beckman Coulter DxI
Insulin (serum) SINSH cobas e 411
Lactulose/13C Mannitol L13CM mass spectrometry
Luteinizing Hormone (LH) CLH Beckman Coulter DxI
Osteocalcin COC Beckman Coulter DxI
Testosterone, high sensitivity CTTMS mass spectrometry
Triglyceride CTRIG cobas c 311