The Histology Core specializes in processing, embedding, sectioning and staining of animal tissues. The core provides researchers with standard hematoxylin-eosin (H&E) staining as well as a variety of standard special stains. The Histology Core also offers veterinary pathology support through GEMpath Inc.
The Histology Core offers veterinary pathology support including full pathology report and photographs if requested.
Blended technician time
The Histology Core team offers blended technician time (chargeable) for additional tasks outside the routine for each service line offered. These services include, but are not limited to:
- Dissecting out organs from the animal if submitted tissues are not already dissected out
- Preparing and conducting complex special stains
The Histology Core offers a variety of special stains, including Masson trichrome, periodic acid-Schiff and Picrosirius red. Other special stains are performed on a time and materials basis.
Unstained slides may be submitted to the Histology Core for H&E staining. When a tissue is submitted for gross to H&E staining, if additional H&E stained slides are requested, additional unstained slides are cut and H&E staining is done.
Additional unstained slides and re-cuts fixed
The Histology Core accepts blocks for additional slides to be cut. For Mayo Clinic investigators, the core team can pull previously blocked tissue if more slides are required.
Gross to unstained slide
The Histology Core receives and processes specimens into a tissue cassette, and processes and embeds the specimens. Once embedded, sections are cut and put onto a slide. The unstained slides are baked for a short time (if baking is requested), packaged, and sent to the investigator.
Gross to H&E
The Histology Core receives and processes specimens into a tissue cassette, and processes and embeds the specimens. Once embedded, sections are cut and put onto a slide. These slides are then stained with hematoxylin-eosin (H&E). Slides are dried overnight and then boxed up and sent to the investigator.
Gross to block
The Histology Core receives specimens and processes the specimens into a tissue cassette, and processes and embeds the specimens into a paraffin block. Paraffin blocks are then packaged and sent to the investigator.