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Results filtered:Study status: Open
The purpose of this study is to evaluate the efficacy and safety of rhu-pGSN plus standard of care (SOC) in subjects with moderate-to-severe ARDS (P/F ratio ≤150) due to pneumonia or other infections.
The objectives of this study are to identify predictors of in-hospital disease progression (prognostic enrichment), to develop an individualized treatment rule (ITR) for steroid use through advanced statistical and machine learning methods (predictive enrichment), and to evaluate an ITR-guided corticosteroid use coupled with biomarker-guided dosing strategy (optimal patient selection and dosing) in community acquired pneumonia (CAP).