Angela M. Donaldson, M.D.

The purpose of this study is to evaluate ciliary structure in both “healthy appearing” and “non-healthy appearing” tissue of the same patient with recalcitrant CRS and endoscopic findings of focal purulent inflammation to better understand if ciliary structure is contributing to the refractory disease. 

The purpose of this study is ti identify biomarkers that can be used to predict safe de-escalation of aspirin (ASA) in patients with AERD.

The purpose of this study is to evaluate ciliary structure in both “healthy appearing” and “non-healthy appearing” tissue of the same patient with recalcitrant CRS and endoscopic findings of focal purulent inflammation to better understand if ciliary structure is contributing to the refractory disease. 

The purpose of this study is to compare change in SNOT-22 score in patients who received medication therapy such as oral antibiotics, topical antibiotics, oral corticosteroids, topical corticosteroids, leukotriene receptor antagonist, and interleukin 5 receptor antagonist following endoscopic sinus surgery versus control in patient with chronic sinusitis with nasal polyps and a positive culture.

This study is utilizing the Mayo Clinic Cures at Home participation services. For questions regarding home research services in this study please reach out to curesathome@mayo.edu.

The purpose of this study is to investigate facial pain improvement with twice-daily use of a novel device combing acoustic vibration with oscillating expiratory pressure compared with a sham device in male and female participants > 18 years of age with sinus pain/headache lacking objective evidence of sinonasal inflammation.