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  • EMPOWER: Endometriosis Diagnosis Using MicroRNA: PrOspective study in Women to Allow Early Disease Recognition (EMPOWER) Rochester, Minn.

    The purpose of this study is to evaluate a non-invasive diagnostic test (DotEndo) for endometriosis. Dot Laboratories, Inc. (DotLab) has identified a panel of circulating microRNAs (miRNAs) that are significantly and differentially expressed between patients with endometriosis compared with control patients with other benign gynecological diseases.

    Endometriosis is a debilitating, chronic inflammatory condition that affects over 5 million women in the United States and approximately 10% of women of reproductive age worldwide. Standard clinical practice for diagnosing endometriosis is through laparoscopy using visual examination. Laparoscopy is an invasive, costly procedure that must be performed by specialists, and carries risks associated with surgery.

    DotEndo is a non-invasive in vitro diagnostic test that measures levels of circulating miRNA biomarkers in whole blood. The DotEndo blood test will use a distinct classifier algorithm, based on levels of disease-specific miRNAs, to aid in the diagnosis of active endometriosis disease. 

Closed for Enrollment

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