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Collection of Adipose Tissue for Regenerative Medicine Research in Cardiovascular Disease
The purpose of this study is to obtain adipose tissue from patients undergoing vascular surgery where EVs can be isolated from the fat and used for research purposes to examine their effect on inflammation and remodeling in culture and in animal models. The samples will immediately be processed to obtain EVs for research purposes - this is not a biorepository. Some surgeries will only obtain fat that would be considered waste; however, other surgeries will be able to safely obtain a larger volume of adipose tissue and for this reason we submit a ‘minimal risk protocol.'
Sex and Age Differences in Ehlers Danlos Syndrome
The purpose of this study is to determine whether serum biomarkers and comorbidities differ between subjects with hEDS/HSD vs. other non-hypermobile EDS subtypes and whether sex and/or age differences exist, and to determine whether serum biomarkers and comorbidities differ between subjects with hEDS vs. HSD and whether sex and/or age differences exist.