Faculty

Ugur T. Sener, M.D.

Clinical Studies

MC230713 Neuro-Oncology Anywhere: Deploying Mayo Clinic’s remote cognitive assessment battery and wearable device monitoring platform while assessing the impact of metformin on cognition and quality of life in patients with history of cranial radiation (Neuro-Oncology Anywhere) Rochester, Minn.
The purpose of this study is to determine the feasibility of completing serial remote cognitive, activity/sleep, and selfreport assessments in clinical trial participants who have previously received cranial radiation.
Patient and caregiver priorities in neuro-oncology care Rochester, Minn.
The purpose of this study is to conduct semi-structured interviews with patients who have primary and metastatic CNS tumors as well as caregivers of these patients.

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Optune® (TTFields, 200 kHz) Concomitant with Maintenance Temozolomide and Pembrolizumab Versus Optune® Concomitant with Maintenance Temozolomide and Placebo for the Treatment of Newly Diagnosed Glioblastoma (EF-41/KEYNOTE D58) Rochester, Minn., Jacksonville, Fla., Scottsdale/Phoenix, Ariz.
The purpose of this study is to compare overall survival (OS) for subjects treated with Optune concomitant with maintenance temozolomide (TMZ) plus pembrolizumab versus those treated with Optune concomitant with maintenance TMZ plus placebo
Hypothesis: Optune concomitant with maintenance TMZ plus pembrolizumab is superior to Optune concomitant with maintenance TMZ plus placebo with respect to OS

Neuro-Oncology Anywhere 242: Pilot Study Evaluating Telehealth and In-person Assessments in Patients with Glioma Receiving Oral Chemotherapy Rochester, Minn.
The purpose of this study is to evaluate the safety, feasibility and acceptability of telehealth assessments for patients with GBM receiving oral chemotherapy.